ES2670580T3 - Procedimiento continuo para preparar partículas de polifluoroacrilato - Google Patents
Procedimiento continuo para preparar partículas de polifluoroacrilato Download PDFInfo
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- ES2670580T3 ES2670580T3 ES11711211.0T ES11711211T ES2670580T3 ES 2670580 T3 ES2670580 T3 ES 2670580T3 ES 11711211 T ES11711211 T ES 11711211T ES 2670580 T3 ES2670580 T3 ES 2670580T3
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- 230000013632 homeostatic process Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- MTNDZQHUAFNZQY-UHFFFAOYSA-N imidazoline Chemical compound C1CN=CN1 MTNDZQHUAFNZQY-UHFFFAOYSA-N 0.000 description 1
- 125000002883 imidazolyl group Chemical group 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 125000001041 indolyl group Chemical group 0.000 description 1
- 238000002354 inductively-coupled plasma atomic emission spectroscopy Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 229910001506 inorganic fluoride Inorganic materials 0.000 description 1
- 239000010954 inorganic particle Substances 0.000 description 1
- 238000005305 interferometry Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 125000002346 iodo group Chemical group I* 0.000 description 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- ZQMHJBXHRFJKOT-UHFFFAOYSA-N methyl 2-[(1-methoxy-2-methyl-1-oxopropan-2-yl)diazenyl]-2-methylpropanoate Chemical compound COC(=O)C(C)(C)N=NC(C)(C)C(=O)OC ZQMHJBXHRFJKOT-UHFFFAOYSA-N 0.000 description 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 1
- WVFLGSMUPMVNTQ-UHFFFAOYSA-N n-(2-hydroxyethyl)-2-[[1-(2-hydroxyethylamino)-2-methyl-1-oxopropan-2-yl]diazenyl]-2-methylpropanamide Chemical compound OCCNC(=O)C(C)(C)N=NC(C)(C)C(=O)NCCO WVFLGSMUPMVNTQ-UHFFFAOYSA-N 0.000 description 1
- QYZFTMMPKCOTAN-UHFFFAOYSA-N n-[2-(2-hydroxyethylamino)ethyl]-2-[[1-[2-(2-hydroxyethylamino)ethylamino]-2-methyl-1-oxopropan-2-yl]diazenyl]-2-methylpropanamide Chemical compound OCCNCCNC(=O)C(C)(C)N=NC(C)(C)C(=O)NCCNCCO QYZFTMMPKCOTAN-UHFFFAOYSA-N 0.000 description 1
- DVEKCXOJTLDBFE-UHFFFAOYSA-N n-dodecyl-n,n-dimethylglycinate Chemical compound CCCCCCCCCCCC[N+](C)(C)CC([O-])=O DVEKCXOJTLDBFE-UHFFFAOYSA-N 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 125000002868 norbornyl group Chemical group C12(CCC(CC1)C2)* 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- FVZVCSNXTFCBQU-UHFFFAOYSA-N phosphanyl Chemical group [PH2] FVZVCSNXTFCBQU-UHFFFAOYSA-N 0.000 description 1
- 125000005499 phosphonyl group Chemical group 0.000 description 1
- LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical group [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920001987 poloxamine Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 238000006479 redox reaction Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 108700004121 sarkosyl Proteins 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 125000003548 sec-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- BBMHARZCALWXSL-UHFFFAOYSA-M sodium dihydrogenphosphate monohydrate Chemical compound O.[Na+].OP(O)([O-])=O BBMHARZCALWXSL-UHFFFAOYSA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000010557 suspension polymerization reaction Methods 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- OPQYOFWUFGEMRZ-UHFFFAOYSA-N tert-butyl 2,2-dimethylpropaneperoxoate Chemical compound CC(C)(C)OOC(=O)C(C)(C)C OPQYOFWUFGEMRZ-UHFFFAOYSA-N 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 238000004876 x-ray fluorescence Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/10—Esters
- C08F20/22—Esters containing halogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/01—Processes of polymerisation characterised by special features of the polymerisation apparatus used
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F212/34—Monomers containing two or more unsaturated aliphatic radicals
- C08F212/36—Divinylbenzene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/22—Esters containing halogen
- C08F220/24—Esters containing halogen containing perhaloalkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
- C08F36/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F236/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F236/22—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having three or more carbon-to-carbon double bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31593710P | 2010-03-20 | 2010-03-20 | |
| US315937P | 2010-03-20 | ||
| PCT/US2011/028950 WO2011119422A1 (en) | 2010-03-20 | 2011-03-18 | Continuous process for preparing polyfluoroacrylate particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2670580T3 true ES2670580T3 (es) | 2018-05-31 |
Family
ID=43989862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11711211.0T Active ES2670580T3 (es) | 2010-03-20 | 2011-03-18 | Procedimiento continuo para preparar partículas de polifluoroacrilato |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9228028B2 (https=) |
| EP (1) | EP2550305B1 (https=) |
| JP (2) | JP6185836B2 (https=) |
| KR (1) | KR101839038B1 (https=) |
| CN (1) | CN102844334A (https=) |
| CA (1) | CA2793862C (https=) |
| ES (1) | ES2670580T3 (https=) |
| MX (1) | MX347224B (https=) |
| PL (1) | PL2550305T3 (https=) |
| PT (1) | PT2550305T (https=) |
| TR (1) | TR201807469T4 (https=) |
| WO (1) | WO2011119422A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014023826A1 (en) | 2012-08-09 | 2014-02-13 | Dsm Ip Assets B.V. | Process for drying polymeric materials |
| KR20210005314A (ko) | 2012-10-08 | 2021-01-13 | 리립사, 인크. | 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제 |
| WO2019220450A1 (en) | 2018-05-16 | 2019-11-21 | Solara Active Pharma Sciences Limited | Process for preparation of patiromer |
| CN113929925B (zh) * | 2020-07-13 | 2023-08-15 | 中国石油化工股份有限公司 | 一种自组装纳米粒子复合材料及其制备方法和应用 |
| CN116323717A (zh) * | 2021-09-13 | 2023-06-23 | 中美华世通生物医药科技(武汉)股份有限公司 | 治疗高钾血症的聚合物药物及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2694700A (en) | 1950-01-21 | 1954-11-16 | Peter L Shanta | Process of suspension polymerization |
| DE1111823B (de) | 1958-04-01 | 1961-07-27 | Gerhard Schwarz Dipl Chem | Verfahren und Vorrichtung zur kontinuierlichen Herstellung von ionenaustauschenden synthetischen stickstoffhaltigen Harzen in Kugelform |
| JPS5336510B2 (https=) | 1972-05-15 | 1978-10-03 | ||
| CA1166413A (en) * | 1980-10-30 | 1984-05-01 | Edward E. Timm | Process and apparatus for preparing uniform size polymer beads |
| US4487898A (en) * | 1981-06-12 | 1984-12-11 | Kanegafuchi Chemical Industry Co., Ltd. | Process of continuous suspension polymerization |
| JPH0632805A (ja) | 1992-07-17 | 1994-02-08 | Asahi Chem Ind Co Ltd | 連続重合プロセスの非定常運転時の制御方法 |
| JP2001055415A (ja) * | 1999-06-08 | 2001-02-27 | Kanegafuchi Chem Ind Co Ltd | イソブチレン系重合体の製造方法 |
| DE60041644D1 (de) | 1999-06-08 | 2009-04-09 | Kaneka Corp | Verfahren zur kontinuierlichen katonischen lebenden polymerisation |
| JP4509279B2 (ja) | 2000-02-02 | 2010-07-21 | 日東電工株式会社 | アクリル系感圧性接着剤の製造方法 |
| EP1411076A1 (en) * | 2002-10-15 | 2004-04-21 | Rohm And Haas Company | Continuous production of crosslinked polymer nanoparticles |
| JP4062121B2 (ja) | 2003-02-21 | 2008-03-19 | 旭硝子株式会社 | フルオロポリマーの製造方法 |
| BRPI0509365B8 (pt) | 2004-03-30 | 2021-05-25 | Ilypsa Inc | composição farmacêutica, kit farmacêutico, e, uso da referida composição |
| JP2009062478A (ja) | 2007-09-07 | 2009-03-26 | Dic Corp | 有機無機複合ヒドロゲルの連続製造方法 |
| US8586184B2 (en) * | 2007-12-13 | 2013-11-19 | Daikin Industries, Ltd. | Fluorine-containing polymer and aqueous treatment agent |
| CN101970504B (zh) | 2008-03-14 | 2013-01-02 | 柯尼卡美能达商用科技株式会社 | 管型流动反应装置、高分子树脂微粒的制造方法 |
| WO2010022381A1 (en) | 2008-08-22 | 2010-02-25 | Relypsa, Inc. | Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties |
| PT2365988E (pt) * | 2008-08-22 | 2015-10-22 | Relypsa Inc | Polímeros de permuta iónica reticulados, composições e uso no tratamento da hipercalemia |
| US8337824B2 (en) * | 2008-08-22 | 2012-12-25 | Relypsa, Inc. | Linear polyol stabilized polyfluoroacrylate compositions |
| US20100111892A1 (en) | 2008-08-22 | 2010-05-06 | Relypsa, Inc. | Crosslinked polyfluoroacrylic acid and processes for the preparation thereof |
-
2011
- 2011-03-18 KR KR1020127026246A patent/KR101839038B1/ko not_active Expired - Fee Related
- 2011-03-18 JP JP2013501329A patent/JP6185836B2/ja not_active Expired - Fee Related
- 2011-03-18 PL PL11711211T patent/PL2550305T3/pl unknown
- 2011-03-18 TR TR2018/07469T patent/TR201807469T4/tr unknown
- 2011-03-18 WO PCT/US2011/028950 patent/WO2011119422A1/en not_active Ceased
- 2011-03-18 MX MX2012010850A patent/MX347224B/es active IP Right Grant
- 2011-03-18 PT PT117112110T patent/PT2550305T/pt unknown
- 2011-03-18 CA CA2793862A patent/CA2793862C/en active Active
- 2011-03-18 US US13/636,162 patent/US9228028B2/en not_active Expired - Fee Related
- 2011-03-18 EP EP11711211.0A patent/EP2550305B1/en not_active Not-in-force
- 2011-03-18 ES ES11711211.0T patent/ES2670580T3/es active Active
- 2011-03-18 CN CN2011800184692A patent/CN102844334A/zh active Pending
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2015
- 2015-04-21 JP JP2015086796A patent/JP2015131974A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2793862C (en) | 2020-07-07 |
| EP2550305B1 (en) | 2018-03-07 |
| JP2013522448A (ja) | 2013-06-13 |
| MX347224B (es) | 2017-04-19 |
| KR20130016252A (ko) | 2013-02-14 |
| EP2550305A1 (en) | 2013-01-30 |
| US9228028B2 (en) | 2016-01-05 |
| MX2012010850A (es) | 2013-01-29 |
| CN102844334A (zh) | 2012-12-26 |
| WO2011119422A1 (en) | 2011-09-29 |
| JP2015131974A (ja) | 2015-07-23 |
| PT2550305T (pt) | 2018-04-20 |
| KR101839038B1 (ko) | 2018-03-16 |
| JP6185836B2 (ja) | 2017-08-23 |
| US20130197170A1 (en) | 2013-08-01 |
| PL2550305T3 (pl) | 2018-08-31 |
| CA2793862A1 (en) | 2011-09-29 |
| TR201807469T4 (tr) | 2018-06-21 |
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