ES2665953T3 - Inmunoensayos que emplean reactivos quimioluminiscentes no particulados - Google Patents
Inmunoensayos que emplean reactivos quimioluminiscentes no particulados Download PDFInfo
- Publication number
- ES2665953T3 ES2665953T3 ES10751173.5T ES10751173T ES2665953T3 ES 2665953 T3 ES2665953 T3 ES 2665953T3 ES 10751173 T ES10751173 T ES 10751173T ES 2665953 T3 ES2665953 T3 ES 2665953T3
- Authority
- ES
- Spain
- Prior art keywords
- analyte
- chemiluminescent
- group
- binding
- binding partner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/403,299 US9347947B2 (en) | 2009-03-12 | 2009-03-12 | Immunoassays employing non-particulate chemiluminescent reagent |
| US403299 | 2009-03-12 | ||
| PCT/US2010/025433 WO2010104683A1 (en) | 2009-03-12 | 2010-02-25 | Immunoassays employing non-particulate chemiluminescent reagent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2665953T3 true ES2665953T3 (es) | 2018-04-30 |
Family
ID=42728663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10751173.5T Active ES2665953T3 (es) | 2009-03-12 | 2010-02-25 | Inmunoensayos que emplean reactivos quimioluminiscentes no particulados |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9347947B2 (enExample) |
| EP (1) | EP2406630B1 (enExample) |
| JP (1) | JP2012520378A (enExample) |
| CN (1) | CN102348980B (enExample) |
| ES (1) | ES2665953T3 (enExample) |
| RU (1) | RU2559581C2 (enExample) |
| WO (1) | WO2010104683A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8153442B2 (en) * | 2009-10-21 | 2012-04-10 | Siemens Healthcare Diagnostics Inc. | Stabilization of signal generation in particles used in assays |
| JP5795184B2 (ja) * | 2011-04-22 | 2015-10-14 | 国立大学法人 奈良先端科学技術大学院大学 | 被検物質の電気化学的検出方法 |
| AU2013326786A1 (en) * | 2012-10-05 | 2015-04-30 | California Institute Of Technology | Methods and systems for microfluidics imaging and analysis |
| CN107325324B (zh) * | 2016-04-28 | 2019-08-20 | 中国石油化工股份有限公司 | 阻燃剂、阻燃防静电组合物和阻燃防静电聚丙烯发泡珠粒 |
| CN109470856B (zh) * | 2016-11-22 | 2022-01-25 | 科美博阳诊断技术(上海)有限公司 | 一种糖类抗原125的免疫测定方法及其系统 |
| CN111272997A (zh) * | 2017-11-27 | 2020-06-12 | 科美诊断技术股份有限公司 | 一种均相免疫检测试剂盒、检测方法及其应用 |
| CN108445216B (zh) * | 2018-02-11 | 2021-10-15 | 科美诊断技术股份有限公司 | 一种人抗缪勒氏管激素测定试剂盒及其制备方法与应用 |
| CN108169497A (zh) * | 2018-02-11 | 2018-06-15 | 北京科美生物技术有限公司 | 人泌乳素检测试剂盒及其制备方法与应用 |
| CN108445239B (zh) * | 2018-02-11 | 2021-11-02 | 科美诊断技术股份有限公司 | 检测β人绒毛膜促性腺激素的均相免疫检测试剂套装及其制备方法和应用 |
| CN114217075B (zh) * | 2018-02-11 | 2024-05-10 | 科美诊断技术股份有限公司 | 检测目标抗-Carp抗体的均相免疫检测试剂套装及其应用 |
| CN110161249A (zh) * | 2018-02-11 | 2019-08-23 | 北京科美生物技术有限公司 | 检测抗-Carp抗体的均相免疫检测试剂盒及其应用 |
| CN108445238A (zh) * | 2018-02-11 | 2018-08-24 | 北京科美生物技术有限公司 | 检测促黄体生成素的均相免疫检测试剂套装及其制备方法和应用 |
| CN117007811A (zh) * | 2018-02-11 | 2023-11-07 | 科美博阳诊断技术(上海)有限公司 | 一种人心肌肌钙蛋白i含量均相快速测定方法及其应用 |
| CN108490194A (zh) * | 2018-02-11 | 2018-09-04 | 北京科美生物技术有限公司 | 检测卵泡刺激素的均相免疫检测试剂套装及其制备方法和应用 |
| CN110161230A (zh) * | 2018-02-11 | 2019-08-23 | 博阳生物科技(上海)有限公司 | 快速检测降钙素原的均相免疫试剂盒、制备方法、检测方法和装置 |
| CN108982879A (zh) * | 2018-04-25 | 2018-12-11 | 上海铭源数康生物芯片有限公司 | 抗缪勒氏管激素光激发化学发光检测试剂盒制备方法及其试剂盒和使用方法 |
| CN116429757A (zh) * | 2018-08-13 | 2023-07-14 | 科美博阳诊断技术(上海)有限公司 | 一种均相化学发光检测试剂盒及其应用 |
| EP3856927B1 (en) * | 2018-09-25 | 2023-01-11 | Siemens Healthcare Diagnostics Inc. | Compositions, kits, and methods for multiplex assays to correct for biotin interference in target analyte measurements |
| CN111505302A (zh) * | 2019-01-31 | 2020-08-07 | 博阳生物科技(上海)有限公司 | 快速检测n末端b型脑钠肽的均相免疫试剂盒、制备方法、检测方法和装置 |
| CN111665236A (zh) * | 2019-03-08 | 2020-09-15 | 上海索昕生物科技有限公司 | 一种发光微阵列芯片的制备方法及其应用 |
| CN111665235A (zh) * | 2019-03-08 | 2020-09-15 | 上海索昕生物科技有限公司 | 一种化学发光微阵列芯片及其应用 |
| CN118150554A (zh) * | 2019-03-08 | 2024-06-07 | 上海索昕生物科技有限公司 | 一种化学发光微阵列芯片的应用 |
| CN116539866A (zh) * | 2019-07-19 | 2023-08-04 | 科美博阳诊断技术(上海)有限公司 | 一种均相化学发光分析的方法及其应用 |
| EP4408880A4 (en) * | 2021-09-30 | 2025-02-26 | Siemens Healthcare Diagnostics, Inc. | COMPOSITIONS, KITS AND METHODS FOR DUPLEX IMMUNOASSAY FOR ANTI-SARS-COV-2 ANTIBODIES |
| CN115947714B (zh) * | 2022-11-01 | 2024-05-14 | 上海泰辉生物科技有限公司 | 光化学缓存剂的合成方法 |
| CN118858262B (zh) * | 2024-07-03 | 2025-04-22 | 上海碧云天生物技术股份有限公司 | 高灵敏单组分化学发光底物、长效储存容器及其应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US4199559A (en) * | 1974-08-12 | 1980-04-22 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4261968A (en) * | 1979-05-10 | 1981-04-14 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| WO1989012232A1 (en) | 1988-06-08 | 1989-12-14 | London Diagnostics, Inc. | Assays utilizing sensitizer-induced production of detectable signals |
| JPH04134304A (ja) | 1990-09-26 | 1992-05-08 | Furukawa Electric Co Ltd:The | 光ファイバ用被覆除去装置 |
| US5578498A (en) * | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
| US6251581B1 (en) * | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| US5340716A (en) | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
| DE4221880A1 (de) * | 1992-07-03 | 1994-01-05 | Alfatec Pharma Gmbh | Feste und flüssige Lösungen von schwer wasserlöslichen Arzneistoffen |
| JPH07509245A (ja) * | 1992-07-20 | 1995-10-12 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 新規化学発光化合物およびその使用方法 |
| DK0653066T3 (da) * | 1992-07-31 | 1998-09-23 | Dade Behring Marburg Gmbh | Fotoaktiverbare kemiluminescerende matricer |
| US7569341B2 (en) * | 1994-01-31 | 2009-08-04 | Trustees Of Boston University | Nucleic acid directed immobilization arrays and methods of assembly |
| US6013439A (en) * | 1995-12-22 | 2000-01-11 | Dade Behring Marburg Gmbh | Detection of differences in nucleic acids |
| DE69736382T2 (de) * | 1996-05-01 | 2007-08-09 | Dade Behring Marburg Gmbh | Chemilumineszente zusammensetungen und ihre verwendung zum nachweis von wasserstoffperoxid |
| FR2750893B1 (fr) | 1996-07-12 | 1998-10-30 | Elf Aquitaine | Procede de synthese de zeolithe avec agitation homogene du milieu, dispositif et application |
| US6531278B1 (en) * | 1998-01-14 | 2003-03-11 | Utah State University | Ligand-DNA composition for capture and detection of contaminants on a solid surface |
| WO1999042838A1 (en) * | 1998-02-18 | 1999-08-26 | Dade Behring Inc. | Chemiluminescent compositions for use in detection of multiple analytes |
| US6365346B1 (en) * | 1998-02-18 | 2002-04-02 | Dade Behring Inc. | Quantitative determination of nucleic acid amplification products |
| DE19808226C1 (de) * | 1998-02-27 | 2000-03-02 | Bruker Analytik Gmbh | Anordnung und Verfahren zur Untersuchung von hydrophilen Makromolekülen in wässriger Lösung |
| US6783947B1 (en) * | 1999-09-09 | 2004-08-31 | Dade Behring Marburg Gmbh | Protecting groups for biological labeling |
| KR100542033B1 (ko) * | 1999-09-29 | 2006-01-10 | 재팬 사이언스 앤드 테크놀로지 에이젼시 | 고감도 면역분석 |
| US6703248B1 (en) * | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
| JP4134304B2 (ja) | 2000-01-14 | 2008-08-20 | 独立行政法人科学技術振興機構 | ラベル剤およびそれを用いた高感度分析方法 |
| US6346384B1 (en) * | 2000-03-27 | 2002-02-12 | Dade Behring Inc. | Real-time monitoring of PCR using LOCI |
| US6797481B1 (en) * | 2000-10-17 | 2004-09-28 | Dade Behring Marburg Gmbh | Simultaneous screening of multiple analytes |
| US7635571B2 (en) * | 2000-12-07 | 2009-12-22 | Siemens Healthcare Diagnostics Products Gmbh | Amplified signal in binding assays |
| IL164376A0 (en) * | 2002-04-03 | 2005-12-18 | Applied Research Systems | Ox4or binding agents, their preparation and pharmaceutical compositions containing them |
| RU2213974C1 (ru) | 2002-04-09 | 2003-10-10 | Баженов Алексей Иванович | Способ одновременного определения нескольких аналитов |
| US6924154B2 (en) * | 2002-08-20 | 2005-08-02 | Quest Diagnostics Investments Incorporated | Hydrophilic chemilumescent acridinium labeling reagents |
| WO2006034417A2 (en) * | 2004-09-17 | 2006-03-30 | Novartis Vaccines And Diagnostics Inc. | Trivalent metal mediated homogeneous luminescent proximity assay |
| US20060166376A1 (en) * | 2005-01-21 | 2006-07-27 | Craig Alan R | Compositions for use as a signal generation component and methods of using same |
| US7723472B2 (en) * | 2005-02-28 | 2010-05-25 | The Regents Of The University Of California | Extracellular matrix binding chimeric proteins and methods of use thereof |
| EP1808493A3 (en) * | 2006-01-13 | 2007-11-21 | Hybrigenics S.A. | Substrates and methods for assaying deubiquitinating enzymes activity |
-
2009
- 2009-03-12 US US12/403,299 patent/US9347947B2/en active Active
-
2010
- 2010-02-25 RU RU2011141265/15A patent/RU2559581C2/ru active
- 2010-02-25 JP JP2011554072A patent/JP2012520378A/ja active Pending
- 2010-02-25 ES ES10751173.5T patent/ES2665953T3/es active Active
- 2010-02-25 CN CN201080010999.8A patent/CN102348980B/zh active Active
- 2010-02-25 EP EP10751173.5A patent/EP2406630B1/en active Active
- 2010-02-25 WO PCT/US2010/025433 patent/WO2010104683A1/en not_active Ceased
-
2016
- 2016-04-18 US US15/131,120 patent/US9720004B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2406630A4 (en) | 2012-09-26 |
| EP2406630A1 (en) | 2012-01-18 |
| US20160231336A1 (en) | 2016-08-11 |
| EP2406630B1 (en) | 2018-01-17 |
| CN102348980A (zh) | 2012-02-08 |
| CN102348980B (zh) | 2015-05-27 |
| US20100233725A1 (en) | 2010-09-16 |
| WO2010104683A1 (en) | 2010-09-16 |
| US9347947B2 (en) | 2016-05-24 |
| RU2559581C2 (ru) | 2015-08-10 |
| JP2012520378A (ja) | 2012-09-06 |
| RU2011141265A (ru) | 2013-04-20 |
| US9720004B2 (en) | 2017-08-01 |
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