ES2647348T3 - Procedimiento para la preparación de derivados de ácido 3,5-bis(fluoroalquil)pirazol-4-carboxílico y 3,5-bis(fluoroalquil)pirazoles - Google Patents
Procedimiento para la preparación de derivados de ácido 3,5-bis(fluoroalquil)pirazol-4-carboxílico y 3,5-bis(fluoroalquil)pirazoles Download PDFInfo
- Publication number
- ES2647348T3 ES2647348T3 ES13701669.7T ES13701669T ES2647348T3 ES 2647348 T3 ES2647348 T3 ES 2647348T3 ES 13701669 T ES13701669 T ES 13701669T ES 2647348 T3 ES2647348 T3 ES 2647348T3
- Authority
- ES
- Spain
- Prior art keywords
- mmol
- group
- chf2
- nmr
- ppm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12356001 | 2012-02-01 | ||
| EP12356001.3A EP2623496A1 (de) | 2012-02-01 | 2012-02-01 | Verfahren zur Herstellung von 3,5-bis (fluoralkyl)-pyrazol-4-carbonsäure-Derivaten und 3,5-bis(fluoralkyl)-pyrazolen |
| PCT/EP2013/051930 WO2013113829A1 (de) | 2012-02-01 | 2013-01-31 | Verfahren zur herstellung von 3,5-bis(fluoralkyl)-pyrazol-4-carbonsäure-derivaten und 3,5-bis(fluoralkyl)-pyrazolen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2647348T3 true ES2647348T3 (es) | 2017-12-21 |
Family
ID=47624109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13701669.7T Active ES2647348T3 (es) | 2012-02-01 | 2013-01-31 | Procedimiento para la preparación de derivados de ácido 3,5-bis(fluoroalquil)pirazol-4-carboxílico y 3,5-bis(fluoroalquil)pirazoles |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9309202B2 (enExample) |
| EP (2) | EP2623496A1 (enExample) |
| JP (1) | JP6155283B2 (enExample) |
| KR (1) | KR101861116B1 (enExample) |
| CN (1) | CN104245676B (enExample) |
| BR (1) | BR112014019036B1 (enExample) |
| DK (1) | DK2809653T3 (enExample) |
| ES (1) | ES2647348T3 (enExample) |
| IL (1) | IL233926B (enExample) |
| IN (1) | IN2014DN07129A (enExample) |
| MX (1) | MX362689B (enExample) |
| TW (1) | TWI609006B (enExample) |
| WO (1) | WO2013113829A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102233203B1 (ko) | 2013-05-22 | 2021-03-26 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 3,5-비스(플루오로알킬)피라졸 유도체의 제조방법 |
| TWI647215B (zh) * | 2013-11-11 | 2019-01-11 | 德商拜耳作物科學股份有限公司 | 自α,α－二鹵胺製備３,５－雙鹵烷基吡唑衍生物之方法 |
| BR112016021874B1 (pt) * | 2014-03-24 | 2021-03-23 | Bayer Cropscience Aktiengesellschaft | Processo para preparar derivados de 3,5-bis(haloalquil)pirazol a partir de alfa,alfa-dihaloaminas e cetiminas e compostos |
| EP3015458A1 (en) * | 2014-11-03 | 2016-05-04 | Bayer CropScience AG | Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines |
| ES2672581T3 (es) * | 2014-06-11 | 2018-06-15 | Bayer Cropscience Aktiengesellschaft | Proceso para la preparación de 3,5-bis(haloalquil)pirazoles por medio de la acilación de cetiminas |
| MX377282B (es) * | 2014-06-11 | 2025-03-07 | Bayer Cropscience Ag | Proceso para preparar derivados de 3,5-bis(haloalquil)pirazol por medio de la acilación de hidrazonas. |
| US10701937B2 (en) | 2015-02-11 | 2020-07-07 | Basf Se | Pesticidal mixture comprising a pyrazole compound, an insecticide and a fungicide |
| MX2017017140A (es) * | 2015-06-26 | 2018-03-09 | Bayer Cropscience Ag | Proceso para la preparacion de pirazoles sustituidos que contienen grupos haloalcoxi-y haloalquiltio a partir de a,a-dihaloalquilaminas y quetiminas. |
| TW202014410A (zh) | 2018-06-18 | 2020-04-16 | 德商拜耳廠股份有限公司 | 二取代的５（３）－吡唑羧酸酯及由烯醇鹽與氟烷基胺基試劑（ｆａｒ）製備其之方法 |
| EP3953336A4 (en) * | 2019-04-06 | 2023-05-03 | Trinapco, Inc | SULFONYLDIAZOLES AND N-(FLUOROSULFONYL)AZOLES AND PROCESS FOR THEIR PRODUCTION |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2004460A6 (es) * | 1987-07-29 | 1989-01-01 | Consejo Superior Investigacion | Procedimiento para la preparacion de derivados de 3-5-bis-(halometil) pirazol |
| JP3533134B2 (ja) * | 1999-02-15 | 2004-05-31 | 三井化学株式会社 | フッ素化剤及びその製法と使用 |
| JP2001192369A (ja) * | 2000-01-12 | 2001-07-17 | Mitsui Chemicals Inc | フッ素含有複素環式芳香族化合物の製造方法および新規ピラゾール環化合物 |
| DE10215292A1 (de) | 2002-02-19 | 2003-08-28 | Bayer Cropscience Ag | Disubstitutierte Pyrazolylcarbocanilide |
| US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
| DE10349500A1 (de) | 2003-10-23 | 2005-06-02 | Bayer Cropscience Ag | Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern |
| TW200738701A (en) * | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| GB0526044D0 (en) * | 2005-12-21 | 2006-02-01 | Syngenta Ltd | Novel herbicides |
| WO2008013622A2 (en) | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| DE102006039909A1 (de) | 2006-08-25 | 2008-03-13 | Bayer Cropscience Ag | Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten |
| WO2008091594A2 (en) * | 2007-01-24 | 2008-07-31 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
| EP2133341A1 (de) | 2008-02-25 | 2009-12-16 | Bayer CropScience AG | Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten |
| EP2100883A1 (de) | 2008-03-10 | 2009-09-16 | Bayer CropScience AG | Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4carbonsäure-Derivaten |
| JP2010083763A (ja) * | 2008-09-29 | 2010-04-15 | Mitsui Chemicals Inc | ピラゾール誘導体およびその製造方法、ならびに殺菌剤 |
-
2012
- 2012-02-01 EP EP12356001.3A patent/EP2623496A1/de not_active Withdrawn
-
2013
- 2013-01-31 WO PCT/EP2013/051930 patent/WO2013113829A1/de not_active Ceased
- 2013-01-31 KR KR1020147023406A patent/KR101861116B1/ko not_active Expired - Fee Related
- 2013-01-31 DK DK13701669.7T patent/DK2809653T3/da active
- 2013-01-31 CN CN201380007228.7A patent/CN104245676B/zh active Active
- 2013-01-31 BR BR112014019036-4A patent/BR112014019036B1/pt active IP Right Grant
- 2013-01-31 EP EP13701669.7A patent/EP2809653B1/de active Active
- 2013-01-31 MX MX2014009203A patent/MX362689B/es active IP Right Grant
- 2013-01-31 JP JP2014555208A patent/JP6155283B2/ja active Active
- 2013-01-31 US US14/375,450 patent/US9309202B2/en active Active
- 2013-01-31 IN IN7129DEN2014 patent/IN2014DN07129A/en unknown
- 2013-01-31 ES ES13701669.7T patent/ES2647348T3/es active Active
- 2013-02-01 TW TW102103944A patent/TWI609006B/zh active
-
2014
- 2014-08-03 IL IL233926A patent/IL233926B/en active IP Right Grant
-
2016
- 2016-03-03 US US15/059,759 patent/US10035773B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2623496A1 (de) | 2013-08-07 |
| US20150011779A1 (en) | 2015-01-08 |
| US9309202B2 (en) | 2016-04-12 |
| JP2015511227A (ja) | 2015-04-16 |
| US20160185731A1 (en) | 2016-06-30 |
| US10035773B2 (en) | 2018-07-31 |
| BR112014019036A2 (pt) | 2017-08-22 |
| TW201336826A (zh) | 2013-09-16 |
| MX362689B (es) | 2019-02-01 |
| KR20140128344A (ko) | 2014-11-05 |
| IL233926B (en) | 2018-08-30 |
| DK2809653T3 (da) | 2017-11-27 |
| IL233926A0 (en) | 2014-09-30 |
| CN104245676B (zh) | 2016-09-21 |
| TWI609006B (zh) | 2017-12-21 |
| WO2013113829A1 (de) | 2013-08-08 |
| MX2014009203A (es) | 2014-11-12 |
| CN104245676A (zh) | 2014-12-24 |
| IN2014DN07129A (enExample) | 2015-04-24 |
| BR112014019036B1 (pt) | 2019-10-08 |
| EP2809653A1 (de) | 2014-12-10 |
| JP6155283B2 (ja) | 2017-06-28 |
| EP2809653B1 (de) | 2017-08-16 |
| KR101861116B1 (ko) | 2018-05-25 |
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