ES2628180T3 - Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa - Google Patents

Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa Download PDF

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Publication number
ES2628180T3
ES2628180T3 ES09794965.5T ES09794965T ES2628180T3 ES 2628180 T3 ES2628180 T3 ES 2628180T3 ES 09794965 T ES09794965 T ES 09794965T ES 2628180 T3 ES2628180 T3 ES 2628180T3
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ES
Spain
Prior art keywords
ddd
glucose
mmol
autophagy
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09794965.5T
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English (en)
Spanish (es)
Inventor
Waldemar Priebe
Marcin Cybulski
Izabela Fokt
Stainslaw Skora
Charles Conrad
Timothy Madden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
University of Texas at Austin
Original Assignee
University of Texas System
University of Texas at Austin
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Publication of ES2628180T3 publication Critical patent/ES2628180T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ES09794965.5T 2008-07-11 2009-06-25 Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa Active ES2628180T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7996808P 2008-07-11 2008-07-11
US79968P 2008-07-11
PCT/US2009/048675 WO2010005799A2 (en) 2008-07-11 2009-06-25 Novel acetates of 2-deoxy monosaccharides with anticancer activity

Publications (1)

Publication Number Publication Date
ES2628180T3 true ES2628180T3 (es) 2017-08-02

Family

ID=41507670

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09794965.5T Active ES2628180T3 (es) 2008-07-11 2009-06-25 Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa

Country Status (10)

Country Link
US (1) US8927506B2 (https=)
EP (1) EP2310020B1 (https=)
JP (2) JP5677951B2 (https=)
CN (1) CN102149388B (https=)
DK (1) DK2310020T3 (https=)
ES (1) ES2628180T3 (https=)
HU (1) HUE033210T2 (https=)
LT (1) LT2310020T (https=)
PL (1) PL2310020T3 (https=)
WO (1) WO2010005799A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9149489B2 (en) 2006-04-27 2015-10-06 Board Of Regents, University Of Texas System Inhibitors of glycolysis useful in the treatment of brain tumors
ES2628180T3 (es) 2008-07-11 2017-08-02 Board Of Regents, The University Of Texas System Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa
WO2012097052A2 (en) * 2011-01-11 2012-07-19 Intertech Bio, Llc Monosaccharide-based compounds for the treatment of proliferative and inflammatory dermatological diseases
WO2012142615A2 (en) * 2011-04-14 2012-10-18 Board Of Regents, The University Of Texas System Auranofin and auranofin analogs useful to treat proliferative disease and disorders
EP2837389A1 (en) * 2012-04-12 2015-02-18 Gifu University Medicinal composition for treating infarction
PL2981270T3 (pl) 2013-04-05 2022-05-09 Board Of Regents, The University Of Texas System Estry 2-deoksy-monosacharydów o działaniu przeciwproliferacyjnym
WO2020035782A1 (en) * 2018-08-13 2020-02-20 Dermin Sp. Z O.O. Molecular probes for analysis of metabolism of glycolysis inhibitors prodrugs and synthesis methods therefore
BR112022018536A2 (pt) * 2020-03-16 2022-11-29 Univ Texas Método para o tratamento de infecções virais com monossacarídeos tipo hexose e seus análogos

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56103197A (en) 1980-01-21 1981-08-18 Wakamoto Pharmaceut Co Ltd Novel d-glucose derivative and antitumor agent containing the same as active constitutent
JPS58167582A (ja) 1982-03-29 1983-10-03 Takeda Chem Ind Ltd 糖ケタ−ルの製造法
US6319695B1 (en) 1991-10-15 2001-11-20 The Scripps Research Insitute Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
ID16479A (id) 1995-06-23 1997-10-02 Oxford Glycosciences Uk Ltd Senyawa-senyawa pengobatan
EE200200565A (et) 2000-03-31 2004-06-15 Angiogene Pharmaceuticals Ltd. Vaskulaarse kahjustava toimega kombinatsioonravi
US6670330B1 (en) 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
JP2004536819A (ja) 2001-06-11 2004-12-09 トランジション・セラピューティックス・インコーポレーテッド ウイルス性、増殖性および炎症性の疾患の治療のためにビタミンｂ１２および治療薬を用いた複合治療
WO2003018598A2 (en) 2001-08-30 2003-03-06 University College Dublin Monosaccharide derivatives
WO2003082301A1 (en) 2002-03-29 2003-10-09 Threshold Pharmaceuticals, Inc. Compositions and methods for treating cancer
WO2004062604A2 (en) * 2003-01-10 2004-07-29 Threshold Pharmaceuticals, Inc. Treatment of cancer with 2-deoxyglucose
CA2431425A1 (en) 2003-06-05 2004-12-05 Angiogene, Inc. Epas1 gene transfer to improve cell therapy
US20050143336A1 (en) 2003-12-30 2005-06-30 Board Of Regents, The University Of Texas System Methods and compositions for improved non-viral gene therapy
WO2006024492A2 (en) 2004-08-30 2006-03-09 Interstitial Therapeutics Medical implant provided with inhibitors of atp synthesis
BRPI0708273A2 (pt) 2006-02-24 2011-05-24 Univ Texas uso de compostos de hexoses
WO2007100728A2 (en) 2006-02-24 2007-09-07 University Of Miami Mannose derivatives for killing tumor cells
US9149489B2 (en) 2006-04-27 2015-10-06 Board Of Regents, University Of Texas System Inhibitors of glycolysis useful in the treatment of brain tumors
EP1881000A1 (en) 2006-07-17 2008-01-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Conjugates of 2-fluoro-2-deoxy-glucose and their uses as anti cancer agents
WO2008131024A1 (en) 2007-04-17 2008-10-30 Board Of Regents, The University Of Texas System Iodo-hexose compounds useful to treat cancer
ES2628180T3 (es) 2008-07-11 2017-08-02 Board Of Regents, The University Of Texas System Nuevos acetatos de 2-desoxi monosacáridos con actividad anticancerosa
WO2012142615A2 (en) 2011-04-14 2012-10-18 Board Of Regents, The University Of Texas System Auranofin and auranofin analogs useful to treat proliferative disease and disorders

Also Published As

Publication number Publication date
EP2310020A2 (en) 2011-04-20
EP2310020A4 (en) 2012-04-25
JP5890043B2 (ja) 2016-03-22
JP2015091849A (ja) 2015-05-14
CN102149388B (zh) 2014-11-05
US20110160151A1 (en) 2011-06-30
JP5677951B2 (ja) 2015-02-25
US8927506B2 (en) 2015-01-06
CN102149388A (zh) 2011-08-10
PL2310020T3 (pl) 2017-10-31
JP2011527678A (ja) 2011-11-04
HUE033210T2 (hu) 2017-11-28
WO2010005799A2 (en) 2010-01-14
LT2310020T (lt) 2017-07-25
EP2310020B1 (en) 2017-03-15
DK2310020T3 (en) 2017-06-26
WO2010005799A3 (en) 2010-04-29

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