ES2599304T3 - Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido - Google Patents

Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido Download PDF

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Publication number
ES2599304T3
ES2599304T3 ES03749157.8T ES03749157T ES2599304T3 ES 2599304 T3 ES2599304 T3 ES 2599304T3 ES 03749157 T ES03749157 T ES 03749157T ES 2599304 T3 ES2599304 T3 ES 2599304T3
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Spain
Prior art keywords
matrix
microprotuberances
stage
microprotube
fluid substance
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Expired - Lifetime
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ES03749157.8T
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Inventor
Alexander G. Lastovich
Jason B. Alarcon
John P. Dekker, Iii
M. Ishaq Haider
John A. Mikszta
Frank E. Martin
Scott A. O'connor
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Una matriz (101) de microprotuberancias para administrar por rotación una sustancia fluida a tejido, comprendiendo dicha matriz (101): al menos una platina circular (102), comprendiendo dicha platina circular (102) una superficie para microprotuberancias y un borde de platina (102) que tiene un grosor, en donde dicha superficie para microprotuberancias es adecuada para fijar una pluralidad de microprotuberancias (10) sobre la misma o en la misma; una pluralidad de microprotuberancias (10) fijadas en o sobre dicha superficie para microprotuberancias 10 de dicha platina circular (102) en una matriz radial (101), en donde cada una de dichas microprotuberancias (10) comprende al menos un borde raspante; y al menos un medio de retención de sustancia fluida, estando dicho medio de retención de sustancia seleccionado del grupo consistente en separación entre microprotuberancias, uno o más rebajes entre dichas microprotuberancias (10), una o más zonas desprovistas de microprotuberancias (10), una o más zonas con densidad reducida de microprotuberancias, una o más zonas con microprotuberancias (10) fijadas a la platina (102) siguiendo un patrón adaptado para dirigir dicha sustancia hacia el interior de dicha matriz (101), uno o más canales en la superficie para fijación de microprotuberancias de la platina (102), y sus combinaciones, en donde dicho medio de retención de sustancia fluida retiene de manera liberable dicha sustancia fluida cuando se utiliza la matriz (101), permitiendo de esta manera que cualquier sustancia fluida que no se administra inmediatamente al tejido permanezca en la matriz (101).

Description

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Claims (1)

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ES03749157.8T 2002-08-29 2003-08-27 Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido Expired - Lifetime ES2599304T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40669402P 2002-08-29 2002-08-29
US406694P 2002-08-29
PCT/US2003/026812 WO2004020015A2 (en) 2002-08-29 2003-08-27 Microprotrusion arrays and methods for using same to deliver substances into tissue

Publications (1)

Publication Number Publication Date
ES2599304T3 true ES2599304T3 (es) 2017-02-01

Family

ID=31978342

Family Applications (4)

Application Number Title Priority Date Filing Date
ES16169887.3T Expired - Lifetime ES2657432T3 (es) 2002-08-29 2003-08-27 Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido
ES03749156.0T Expired - Lifetime ES2537171T3 (es) 2002-08-29 2003-08-27 Micro-raspador con características de raspado controladas
ES03749157.8T Expired - Lifetime ES2599304T3 (es) 2002-08-29 2003-08-27 Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido
ES03751906.3T Expired - Lifetime ES2617576T3 (es) 2002-08-29 2003-08-27 Administración de sustancias mediante un sistema microabrasivo giratorio

Family Applications Before (2)

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ES16169887.3T Expired - Lifetime ES2657432T3 (es) 2002-08-29 2003-08-27 Matrices de microprotuberancias y métodos para utilizarlas para administrar sustancias a tejido
ES03749156.0T Expired - Lifetime ES2537171T3 (es) 2002-08-29 2003-08-27 Micro-raspador con características de raspado controladas

Family Applications After (1)

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ES03751906.3T Expired - Lifetime ES2617576T3 (es) 2002-08-29 2003-08-27 Administración de sustancias mediante un sistema microabrasivo giratorio

Country Status (7)

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US (5) US7316671B2 (es)
EP (4) EP1531896B1 (es)
JP (3) JP4460451B2 (es)
AU (3) AU2003268206B2 (es)
CA (3) CA2497103C (es)
ES (4) ES2657432T3 (es)
WO (3) WO2004020015A2 (es)

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