ES2594706T3 - Péptidos biológicamente activos - Google Patents

Péptidos biológicamente activos Download PDF

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Publication number
ES2594706T3
ES2594706T3 ES09743243.9T ES09743243T ES2594706T3 ES 2594706 T3 ES2594706 T3 ES 2594706T3 ES 09743243 T ES09743243 T ES 09743243T ES 2594706 T3 ES2594706 T3 ES 2594706T3
Authority
ES
Spain
Prior art keywords
seq
bls
peptide
ttds
wdlyfeivw
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09743243.9T
Other languages
English (en)
Spanish (es)
Inventor
Friedrich Scheiflinger
Michael Dockal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxalta GmbH
Baxalta Inc
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Application granted granted Critical
Publication of ES2594706T3 publication Critical patent/ES2594706T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
ES09743243.9T 2008-04-17 2009-04-16 Péptidos biológicamente activos Active ES2594706T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US932608P 2008-04-17 2008-04-17
US9326P 2008-04-17
US11305508P 2008-11-10 2008-11-10
US113055P 2008-11-10
PCT/US2009/040857 WO2009137256A1 (fr) 2008-04-17 2009-04-16 Peptides biologiquement actifs

Publications (1)

Publication Number Publication Date
ES2594706T3 true ES2594706T3 (es) 2016-12-22

Family

ID=40887122

Family Applications (2)

Application Number Title Priority Date Filing Date
ES16172509T Active ES2739676T3 (es) 2008-04-17 2009-04-16 Péptidos biológicamente activos
ES09743243.9T Active ES2594706T3 (es) 2008-04-17 2009-04-16 Péptidos biológicamente activos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES16172509T Active ES2739676T3 (es) 2008-04-17 2009-04-16 Péptidos biológicamente activos

Country Status (19)

Country Link
US (6) US8563688B2 (fr)
EP (2) EP3115370B1 (fr)
JP (3) JP6038452B2 (fr)
KR (2) KR101434712B1 (fr)
CN (2) CN102007140B (fr)
AR (1) AR071478A1 (fr)
AU (1) AU2009244635B2 (fr)
BR (1) BRPI0911203A2 (fr)
CA (1) CA2721694C (fr)
DK (2) DK2279200T3 (fr)
ES (2) ES2739676T3 (fr)
HK (2) HK1154255A1 (fr)
MX (1) MX2010011397A (fr)
NZ (1) NZ588200A (fr)
PL (1) PL2279200T3 (fr)
PT (1) PT2279200T (fr)
SG (2) SG10201809286XA (fr)
TW (2) TWI541020B (fr)
WO (1) WO2009137256A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI541020B (zh) * 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽
AU2010290077C1 (en) 2009-08-24 2015-12-03 Bioverativ Therapeutics Inc. Coagulation factor IX compositions and methods of making and using same
CN103262532B (zh) 2010-07-19 2018-03-09 杜比实验室特许公司 用于经采样复用的图像和视频数据的增强方法
PL2717898T3 (pl) 2011-06-10 2019-06-28 Bioverativ Therapeutics Inc. Związki o działaniu prokoagulacyjnym i sposoby ich stosowania
EP3549953A1 (fr) 2012-02-15 2019-10-09 Bioverativ Therapeutics Inc. Protéines de facteur viii de recombinaison
ES2771208T3 (es) 2012-02-15 2020-07-06 Bioverativ Therapeutics Inc Composiciones de factor VIII y métodos de preparación y uso de las mismas
JP6246894B2 (ja) * 2013-06-11 2017-12-13 シージェイ チェイルジェダング コーポレイション L−イソロイシンを生産する微生物及びこれを用いたl−イソロイシン製造方法
WO2015023891A2 (fr) 2013-08-14 2015-02-19 Biogen Idec Ma Inc. Fusions de facteur vii-xten et leurs utilisations
WO2015023894A1 (fr) 2013-08-14 2015-02-19 Biogen Idec Ma Inc. Protéines de facteur viii de recombinaison
EP3065769A4 (fr) 2013-11-08 2017-05-31 Biogen MA Inc. Composé de fusion procoagulant
US20160039876A1 (en) 2014-03-28 2016-02-11 Claresa Levetan Insulin independence among patients with diabetes utilizing an optimized hamster reg3 gamma peptide
JP6484468B2 (ja) * 2014-06-03 2019-03-13 AvanStrate株式会社 ガラス板製造方法およびガラス板製造装置
GB201410507D0 (en) * 2014-06-12 2014-07-30 Univ Bath Drug delivery enhancement agents
EA201890423A1 (ru) 2015-08-03 2018-07-31 Биовератив Терапьютикс Инк. Слитые белки фактора ix, способы их получения и применения
US11111271B2 (en) 2016-09-28 2021-09-07 Cohbar, Inc. Therapeutic peptides
AU2018215092A1 (en) 2017-01-31 2019-08-29 Bioverativ Therapeutics Inc. Factor IX fusion proteins and methods of making and using same

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447356A (en) * 1981-04-17 1984-05-08 Olivera Baldomero M Conotoxins
IT1190891B (it) 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
US5122614A (en) 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5093317A (en) * 1989-06-05 1992-03-03 Cephalon, Inc. Treating disorders by application of insulin-like growth factor
JPH0725794B2 (ja) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 新規なペプチド
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US6037452A (en) * 1992-04-10 2000-03-14 Alpha Therapeutic Corporation Poly(alkylene oxide)-Factor VIII or Factor IX conjugate
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
BR9405798A (pt) 1993-02-22 1995-12-12 Vivorx Pharmaceuticals Inc Métodos para liberação in vivo de material biológico e composições úteis dos mesmos
WO1996021024A1 (fr) * 1994-12-30 1996-07-11 Asgrow Seed Company Gene de replicase du virus de la decoloration foliaire de la papaye
US5532153A (en) * 1995-03-23 1996-07-02 New England Biolabs, Inc. Method for cloning and producing the SacI restriction endonuclease
US7279548B2 (en) * 1996-04-03 2007-10-09 Cytogen Corporation Identification and isolation of novel polypeptides having WW domains and methods of using same
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7109170B2 (en) 1999-06-16 2006-09-19 Saint Louis University Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor
US6624289B1 (en) * 1999-06-16 2003-09-23 Saint Louis University Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor
JP2003503426A (ja) 1999-07-02 2003-01-28 ジェネンテック・インコーポレーテッド FVIIaアンタゴニスト
AT411997B (de) 1999-09-14 2004-08-26 Baxter Ag Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
WO2001039799A2 (fr) * 1999-12-06 2001-06-07 Panacea Pharmaceuticals, Llc. Desensibilisation passive
US20020197266A1 (en) * 2000-02-08 2002-12-26 Waldemar Debinski Immunotherapy using interleukin 13 receptor subunit alpha 2
EP1385872A4 (fr) * 2001-05-11 2004-12-15 Res Dev Foundation Inhibiteurs de recepteur activateur de nf-kappa b et utilisations de ces inhibiteurs
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20060204503A1 (en) * 2005-01-31 2006-09-14 Biogen Idec Ma Inc. Treatment of cancer using antibodies to polypeptides differentially expressed in human lung tumors
WO2007065691A2 (fr) * 2005-12-07 2007-06-14 Technische Universität München Petits ligands d'affinite peptidiques et peptido-mimetiques pour le facteur viii et pour des proteines similaires au facteur viii
KR20080087148A (ko) 2006-01-04 2008-09-30 두-쿱 테크놀로지스 리미티드 저온보호 조성물 및 그 이용방법
TWI541020B (zh) * 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽

Also Published As

Publication number Publication date
TWI541020B (zh) 2016-07-11
SG10201809286XA (en) 2018-11-29
KR20130112959A (ko) 2013-10-14
ES2739676T3 (es) 2020-02-03
JP2014074052A (ja) 2014-04-24
DK3115370T3 (da) 2019-07-29
EP2279200B1 (fr) 2016-07-13
US20190225648A1 (en) 2019-07-25
US10822376B2 (en) 2020-11-03
MX2010011397A (es) 2010-11-12
CN105524163A (zh) 2016-04-27
EP3115370A1 (fr) 2017-01-11
EP3115370B1 (fr) 2019-06-26
TW200944226A (en) 2009-11-01
HK1154255A1 (zh) 2012-04-13
EP2279200A1 (fr) 2011-02-02
NZ588200A (en) 2012-11-30
US20160060295A1 (en) 2016-03-03
US20170174724A1 (en) 2017-06-22
US10287319B2 (en) 2019-05-14
US8563688B2 (en) 2013-10-22
US20100022445A1 (en) 2010-01-28
JP5977223B2 (ja) 2016-08-24
CA2721694C (fr) 2018-11-06
JP2017019797A (ja) 2017-01-26
US8822638B2 (en) 2014-09-02
DK2279200T3 (en) 2016-08-22
AR071478A1 (es) 2010-06-23
TWI573806B (zh) 2017-03-11
WO2009137256A1 (fr) 2009-11-12
CA2721694A1 (fr) 2009-11-12
US20120077749A1 (en) 2012-03-29
PL2279200T3 (pl) 2017-08-31
CN102007140B (zh) 2016-02-24
SG10201608071YA (en) 2016-11-29
US20150038676A1 (en) 2015-02-05
AU2009244635A1 (en) 2009-11-12
BRPI0911203A2 (pt) 2016-07-05
KR101606248B1 (ko) 2016-03-24
JP2011518179A (ja) 2011-06-23
JP6038452B2 (ja) 2016-12-07
US9598464B2 (en) 2017-03-21
TW201443085A (zh) 2014-11-16
AU2009244635B2 (en) 2012-04-19
KR20110005873A (ko) 2011-01-19
KR101434712B1 (ko) 2014-10-01
CN102007140A (zh) 2011-04-06
PT2279200T (pt) 2016-10-12
HK1223946A1 (zh) 2017-08-11
US9206234B2 (en) 2015-12-08

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