ES2582652T3 - Anticuerpos anti-FGF19 y métodos de uso de los mismos - Google Patents

Anticuerpos anti-FGF19 y métodos de uso de los mismos Download PDF

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Publication number
ES2582652T3
ES2582652T3 ES07797128.1T ES07797128T ES2582652T3 ES 2582652 T3 ES2582652 T3 ES 2582652T3 ES 07797128 T ES07797128 T ES 07797128T ES 2582652 T3 ES2582652 T3 ES 2582652T3
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Spain
Prior art keywords
fgf19
antibody
cell
antibodies
cancer
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Active
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ES07797128.1T
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English (en)
Spanish (es)
Inventor
Luc Desnoyers
Dorothy French
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES07797128.1T 2006-02-10 2007-02-09 Anticuerpos anti-FGF19 y métodos de uso de los mismos Active ES2582652T3 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77231006P 2006-02-10 2006-02-10
US772310P 2006-02-10
US78060806P 2006-03-09 2006-03-09
US780608P 2006-03-09
US88586607P 2007-01-19 2007-01-19
US885866P 2007-01-19
PCT/US2007/061936 WO2007136893A2 (en) 2006-02-10 2007-02-09 Anti-fgf19 antibodies and methods using same

Publications (1)

Publication Number Publication Date
ES2582652T3 true ES2582652T3 (es) 2016-09-14

Family

ID=38723925

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07797128.1T Active ES2582652T3 (es) 2006-02-10 2007-02-09 Anticuerpos anti-FGF19 y métodos de uso de los mismos

Country Status (10)

Country Link
US (4) US7678373B2 (https=)
EP (1) EP1989230B1 (https=)
JP (1) JP5209505B2 (https=)
AR (1) AR059432A1 (https=)
AU (1) AU2007254005B2 (https=)
CA (1) CA2637988A1 (https=)
ES (1) ES2582652T3 (https=)
NZ (1) NZ569957A (https=)
TW (1) TWI388568B (https=)
WO (1) WO2007136893A2 (https=)

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US20140294820A1 (en) * 2011-06-24 2014-10-02 University Of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
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US10112987B2 (en) 2012-01-09 2018-10-30 Icb International, Inc. Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide
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Also Published As

Publication number Publication date
CA2637988A1 (en) 2007-11-29
US20120128675A1 (en) 2012-05-24
HK1120273A1 (zh) 2009-03-27
JP2009525764A (ja) 2009-07-16
TW200808827A (en) 2008-02-16
US8293241B2 (en) 2012-10-23
US20100129381A1 (en) 2010-05-27
TWI388568B (zh) 2013-03-11
AU2007254005B2 (en) 2012-11-29
EP1989230B1 (en) 2016-06-01
US7846691B2 (en) 2010-12-07
JP5209505B2 (ja) 2013-06-12
EP1989230A2 (en) 2008-11-12
US20110086032A1 (en) 2011-04-14
AR059432A1 (es) 2008-04-09
WO2007136893A3 (en) 2008-05-15
US20070248604A1 (en) 2007-10-25
WO2007136893A2 (en) 2007-11-29
US7678373B2 (en) 2010-03-16
AU2007254005A1 (en) 2007-11-29
NZ569957A (en) 2012-03-30
US8241633B2 (en) 2012-08-14

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