ES2537785T3 - Péptidos de alfa timosina como potenciadores de vacunas - Google Patents
Péptidos de alfa timosina como potenciadores de vacunas Download PDFInfo
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- ES2537785T3 ES2537785T3 ES10772928.7T ES10772928T ES2537785T3 ES 2537785 T3 ES2537785 T3 ES 2537785T3 ES 10772928 T ES10772928 T ES 10772928T ES 2537785 T3 ES2537785 T3 ES 2537785T3
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- vaccine
- thymosin peptide
- thymosin
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- vaccination
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| US17662509P | 2009-05-08 | 2009-05-08 | |
| US176625P | 2009-05-08 | ||
| US23793209P | 2009-08-28 | 2009-08-28 | |
| US32315510P | 2010-04-12 | 2010-04-12 | |
| PCT/US2010/034221 WO2010129947A2 (en) | 2009-05-08 | 2010-05-10 | Alpha thymosin peptides as vaccine enhancers |
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| EP2675272A4 (en) * | 2011-02-09 | 2015-03-11 | Sciclone Pharmaceuticals Inc | THYMOSINE ALPHA PEPTIDE FOR THE PREVENTION, TREATMENT AND TREATMENT OF INFECTIONS |
| AU2012324398A1 (en) * | 2011-10-20 | 2014-05-01 | Seqirus UK Limited | Adjuvanted influenza B virus vaccines for pediatric priming |
| US20130296223A1 (en) * | 2012-03-30 | 2013-11-07 | Sciclone Pharmaceuticals, Inc. | Use of thymosin alpha for the treatment of sepsis |
| CN103145853B (zh) * | 2013-03-05 | 2014-06-11 | 河南科技大学 | 重组Tα1-BP5融合肽、基因、工程菌及应用 |
| CN109793891A (zh) * | 2017-11-17 | 2019-05-24 | 韩震 | 多肽化合物在制备提高治疗性抗体疗效的佐剂中的应用与组合物及其制备方法 |
| CN112239784A (zh) * | 2019-07-19 | 2021-01-19 | 首都医科大学附属北京佑安医院 | Ifitm3多态性在制备检测老年肾透析患者分泌h3n2抗体水平产品中的应用 |
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| DE3100974A1 (de) | 1980-01-18 | 1982-01-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente |
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| US4560676A (en) | 1980-04-07 | 1985-12-24 | The Rockefeller University | N.sup.α -desacetylthymosinα1 and process |
| US4293455A (en) | 1980-04-07 | 1981-10-06 | Rockefeller University | N.sup.α -Desacetylthymosinα1 and process |
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| US4444757A (en) | 1981-11-16 | 1984-04-24 | Research Corporation | Use of thymosin as an anti-diabetes and anti-hypertensive disease agent |
| US6106868A (en) | 1990-08-24 | 2000-08-22 | The Board Of Governors Of Wayne State University | Method for the treatment of hepatitis |
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| US5620896A (en) | 1992-03-23 | 1997-04-15 | University Of Massachusetts Medical Center | DNA vaccines against rotavirus infections |
| US5432165A (en) | 1992-04-06 | 1995-07-11 | Oclassen Pharmaceuticals, Inc. | Methods for the treatment of infection caused by Hepatitis B virus (HBV) |
| AU4671193A (en) | 1992-07-13 | 1994-01-31 | Kenneth E. Sherman | Composition and method of treating hepatitis b |
| CN1094310A (zh) | 1992-12-15 | 1994-11-02 | 托马斯·C·梅里根 | 人体免疫缺陷性病毒感染用组合式化学疗法 |
| CN1072961C (zh) | 1993-03-05 | 2001-10-17 | 施塞克龙药品公司 | 治疗对干扰素治疗无反应者的丙型肝炎的方法 |
| US6200952B1 (en) | 1993-06-02 | 2001-03-13 | Sciclone Pharmaceuticals, Inc. | Combination therapy method for treating chronic hepatitis B |
| TW249754B (OSRAM) | 1993-10-26 | 1995-06-21 | Alpha I Biomedicals Inc | |
| WO1995012405A1 (en) | 1993-11-05 | 1995-05-11 | Alpha 1 Biomedicals, Inc. | Method and composition for treatment of patients having decompensated liver disease |
| US5750501A (en) | 1993-11-05 | 1998-05-12 | Alpha 1 Biomedicals, Inc. | Method and composition for treatment of patients having decompensated liver disease |
| US5888980A (en) | 1994-06-30 | 1999-03-30 | Bio-Logic Research And Development Corporation | Compositions for enhancing immune function |
| US5632983A (en) | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
| US5880980A (en) * | 1996-09-30 | 1999-03-09 | Rockwell International Corporation | Distributed decimation sample rate conversion |
| US5939423A (en) | 1997-04-16 | 1999-08-17 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir |
| US6172046B1 (en) | 1997-09-21 | 2001-01-09 | Schering Corporation | Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection |
| ATE206618T1 (de) | 1997-09-21 | 2001-10-15 | Schering Corp | Kombinationstherapie zur entfernung von nachweisbarer hcv-rns in patienten mit chronischer hepatitis c-infektion |
| CN1230198C (zh) | 1998-05-15 | 2005-12-07 | 先灵公司 | 给首次接受抗病毒疗法的G慢性丙型肝炎感染患者施用包括利巴韦林和α干扰素的联合疗法 |
| CN1170543C (zh) | 1998-06-08 | 2004-10-13 | 弗·哈夫曼-拉罗切有限公司 | PEG-IFN-α和三唑核苷在治疗慢性丙型肝炎中的用途 |
| US20050037018A1 (en) | 2003-06-20 | 2005-02-17 | Innogentics N.V. | HCV combination therapy |
| US6288033B1 (en) | 1998-09-25 | 2001-09-11 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir |
| US7208167B2 (en) | 2000-08-07 | 2007-04-24 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis C with thymosin and peptide combination therapy |
| EP1311279B1 (en) | 2000-08-07 | 2006-12-20 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis c with thymosin, interferon and ribavirin |
| US20050020495A1 (en) | 2001-10-24 | 2005-01-27 | Martins Eduardo Bruno Guimaraes | Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors |
| EP1446159A4 (en) | 2001-10-26 | 2005-06-01 | Irx Therapeutics Inc | IMMUNOTHERAPY FOR REVERSING AN IMMUNE UPPRESSION |
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| UA78726C2 (en) * | 2001-11-01 | 2007-04-25 | Sciclone Pharmaceuticals Inc | Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment |
| UA80957C2 (en) | 2001-11-01 | 2007-11-26 | Sciclone Pharmaceuticals Inc | Method of administering a thymosin alpha 1 peptide |
| EA009945B1 (ru) | 2003-04-23 | 2008-04-28 | Сциклон Фармасьютикалс, Инк. | Способ лечения или профилактики респираторной коронавирусной инфекции с использованием пептидов альфа-тимозина |
| US20100311656A1 (en) | 2003-04-23 | 2010-12-09 | Sciclone Pharmaceuticals, Inc. | Treatment or prevention of respiratory viral infections with alpha thymosin peptides |
| CN101072582B (zh) | 2004-12-06 | 2012-06-27 | 赛生制药有限公司 | 作为癌症疫苗佐剂的α胸腺肽 |
| CN100341571C (zh) | 2005-09-16 | 2007-10-10 | 孙介光 | 一种治疗肿瘤的药物及该药物在制备治疗肿瘤药物中应用 |
| KR101380360B1 (ko) | 2006-05-02 | 2014-04-09 | 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. | 거대세포바이러스 감염의 치료를 위한, 단독으로 또는 피티엑스 3 또는 강시클로비어와 병용되는 티모신 알파1의 용도 |
| CA2648889C (en) | 2006-05-19 | 2016-02-23 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A | Use of thymosin alpha 1 for the treatment of immunological diseases |
| WO2009079338A1 (en) | 2007-12-14 | 2009-06-25 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa) |
-
2010
- 2010-05-10 US US12/776,976 patent/US8716012B2/en active Active
- 2010-05-10 WO PCT/US2010/034221 patent/WO2010129947A2/en not_active Ceased
- 2010-05-10 EP EP10772928.7A patent/EP2427213B1/en active Active
- 2010-05-10 JP JP2012510041A patent/JP2012526149A/ja not_active Withdrawn
- 2010-05-10 CN CN201080030714.7A patent/CN102458470B/zh active Active
- 2010-05-10 ES ES10772928.7T patent/ES2537785T3/es active Active
-
2015
- 2015-03-20 JP JP2015057490A patent/JP5766894B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2427213B1 (en) | 2015-04-01 |
| EP2427213A4 (en) | 2013-08-21 |
| WO2010129947A3 (en) | 2011-03-10 |
| US8716012B2 (en) | 2014-05-06 |
| JP2012526149A (ja) | 2012-10-25 |
| EP2427213A2 (en) | 2012-03-14 |
| JP2015134808A (ja) | 2015-07-27 |
| US20100285060A1 (en) | 2010-11-11 |
| CN102458470A (zh) | 2012-05-16 |
| CN102458470B (zh) | 2016-01-20 |
| WO2010129947A2 (en) | 2010-11-11 |
| JP5766894B2 (ja) | 2015-08-19 |
| HK1170669A1 (zh) | 2013-03-08 |
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