JP2012526149A - ワクチン増強剤としてのαチモシンペプチド - Google Patents
ワクチン増強剤としてのαチモシンペプチド Download PDFInfo
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- JP2012526149A JP2012526149A JP2012510041A JP2012510041A JP2012526149A JP 2012526149 A JP2012526149 A JP 2012526149A JP 2012510041 A JP2012510041 A JP 2012510041A JP 2012510041 A JP2012510041 A JP 2012510041A JP 2012526149 A JP2012526149 A JP 2012526149A
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| JP2014532620A (ja) * | 2011-10-20 | 2014-12-08 | ノバルティス アーゲー | 小児の初回免疫のためのアジュバント添加インフルエンザｂウイルスワクチン |
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| CN101072582B (zh) * | 2004-12-06 | 2012-06-27 | 赛生制药有限公司 | 作为癌症疫苗佐剂的α胸腺肽 |
| EP2675272A4 (en) * | 2011-02-09 | 2015-03-11 | Sciclone Pharmaceuticals Inc | THYMOSINE ALPHA PEPTIDE FOR THE PREVENTION, TREATMENT AND TREATMENT OF INFECTIONS |
| US20130296223A1 (en) * | 2012-03-30 | 2013-11-07 | Sciclone Pharmaceuticals, Inc. | Use of thymosin alpha for the treatment of sepsis |
| CN103145853B (zh) * | 2013-03-05 | 2014-06-11 | 河南科技大学 | 重组Tα1-BP5融合肽、基因、工程菌及应用 |
| CN109793891A (zh) * | 2017-11-17 | 2019-05-24 | 韩震 | 多肽化合物在制备提高治疗性抗体疗效的佐剂中的应用与组合物及其制备方法 |
| CN112239784A (zh) * | 2019-07-19 | 2021-01-19 | 首都医科大学附属北京佑安医院 | Ifitm3多态性在制备检测老年肾透析患者分泌h3n2抗体水平产品中的应用 |
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| US8018A (en) * | 1851-04-01 | Improvement in seed-planters | ||
| JP2005506997A (ja) * | 2001-10-26 | 2005-03-10 | ロード・アイランド・ホスピタル | 遺伝的免疫化のチモシン増強 |
| JP2008523067A (ja) * | 2004-12-06 | 2008-07-03 | サイクローン・ファーマシューティカルズ・インコーポレイテッド | 癌ワクチンアジュバントとしてのαサイモシンペプチド |
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| US4077949A (en) | 1973-12-28 | 1978-03-07 | Sloan-Kettering Institute For Cancer Research | Polypeptide hormones of the thymus |
| DE2604845A1 (de) | 1976-02-07 | 1977-08-18 | Knoll Ag | Neue piperazinderivate |
| US4079127A (en) | 1976-10-28 | 1978-03-14 | Board Of Regents Of The University Of Texas | Thymosin alpha 1 |
| DE3100974A1 (de) | 1980-01-18 | 1982-01-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente |
| US4612365A (en) | 1980-03-25 | 1986-09-16 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften | Medicaments containing alpha 1-thymosin and having an immuno regulatory action and alpha 1-thymosin fragments |
| US4560676A (en) | 1980-04-07 | 1985-12-24 | The Rockefeller University | N.sup.α -desacetylthymosinα1 and process |
| US4293455A (en) | 1980-04-07 | 1981-10-06 | Rockefeller University | N.sup.α -Desacetylthymosinα1 and process |
| US4361673A (en) | 1980-09-19 | 1982-11-30 | American Home Products Corporation | Polypeptide compositions |
| US4444757A (en) | 1981-11-16 | 1984-04-24 | Research Corporation | Use of thymosin as an anti-diabetes and anti-hypertensive disease agent |
| US6106868A (en) | 1990-08-24 | 2000-08-22 | The Board Of Governors Of Wayne State University | Method for the treatment of hepatitis |
| TW224053B (OSRAM) | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
| US5308833A (en) | 1992-02-06 | 1994-05-03 | Sciclone Pharmaceuticals | Method for treating hepatitis B carriers with minimal disease |
| US5620896A (en) | 1992-03-23 | 1997-04-15 | University Of Massachusetts Medical Center | DNA vaccines against rotavirus infections |
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| CN1094310A (zh) | 1992-12-15 | 1994-11-02 | 托马斯·C·梅里根 | 人体免疫缺陷性病毒感染用组合式化学疗法 |
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| US5632983A (en) | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
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| US6172046B1 (en) | 1997-09-21 | 2001-01-09 | Schering Corporation | Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection |
| ATE206618T1 (de) | 1997-09-21 | 2001-10-15 | Schering Corp | Kombinationstherapie zur entfernung von nachweisbarer hcv-rns in patienten mit chronischer hepatitis c-infektion |
| CN1230198C (zh) | 1998-05-15 | 2005-12-07 | 先灵公司 | 给首次接受抗病毒疗法的G慢性丙型肝炎感染患者施用包括利巴韦林和α干扰素的联合疗法 |
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| US20050037018A1 (en) | 2003-06-20 | 2005-02-17 | Innogentics N.V. | HCV combination therapy |
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| US7208167B2 (en) | 2000-08-07 | 2007-04-24 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis C with thymosin and peptide combination therapy |
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| US20050020495A1 (en) | 2001-10-24 | 2005-01-27 | Martins Eduardo Bruno Guimaraes | Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors |
| EP1446159A4 (en) | 2001-10-26 | 2005-06-01 | Irx Therapeutics Inc | IMMUNOTHERAPY FOR REVERSING AN IMMUNE UPPRESSION |
| UA78726C2 (en) * | 2001-11-01 | 2007-04-25 | Sciclone Pharmaceuticals Inc | Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment |
| UA80957C2 (en) | 2001-11-01 | 2007-11-26 | Sciclone Pharmaceuticals Inc | Method of administering a thymosin alpha 1 peptide |
| EA009945B1 (ru) | 2003-04-23 | 2008-04-28 | Сциклон Фармасьютикалс, Инк. | Способ лечения или профилактики респираторной коронавирусной инфекции с использованием пептидов альфа-тимозина |
| US20100311656A1 (en) | 2003-04-23 | 2010-12-09 | Sciclone Pharmaceuticals, Inc. | Treatment or prevention of respiratory viral infections with alpha thymosin peptides |
| CN100341571C (zh) | 2005-09-16 | 2007-10-10 | 孙介光 | 一种治疗肿瘤的药物及该药物在制备治疗肿瘤药物中应用 |
| KR101380360B1 (ko) | 2006-05-02 | 2014-04-09 | 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. | 거대세포바이러스 감염의 치료를 위한, 단독으로 또는 피티엑스 3 또는 강시클로비어와 병용되는 티모신 알파1의 용도 |
| CA2648889C (en) | 2006-05-19 | 2016-02-23 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A | Use of thymosin alpha 1 for the treatment of immunological diseases |
| WO2009079338A1 (en) | 2007-12-14 | 2009-06-25 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa) |
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- 2010-05-10 JP JP2012510041A patent/JP2012526149A/ja not_active Withdrawn
- 2010-05-10 CN CN201080030714.7A patent/CN102458470B/zh active Active
- 2010-05-10 ES ES10772928.7T patent/ES2537785T3/es active Active
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2015
- 2015-03-20 JP JP2015057490A patent/JP5766894B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8018A (en) * | 1851-04-01 | Improvement in seed-planters | ||
| JP2005506997A (ja) * | 2001-10-26 | 2005-03-10 | ロード・アイランド・ホスピタル | 遺伝的免疫化のチモシン増強 |
| JP2008523067A (ja) * | 2004-12-06 | 2008-07-03 | サイクローン・ファーマシューティカルズ・インコーポレイテッド | 癌ワクチンアジュバントとしてのαサイモシンペプチド |
Non-Patent Citations (1)
| Title |
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| JPN6014024061; Ｗｉｌｌｉａｍ Ｂ． Ｅｒｓｈｌｅｒ ｅｔ ａｌ: Ａｎｎａｌｓ ｏｆ ｔｈｅ Ｎｅｗ Ｙｏｒｋ Ａｃａｄｅｍｙ ｏｆ Ｓｃｉｅｎｃｅｓ １１１２, 2007, ｐ．３７５-３８４ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014532620A (ja) * | 2011-10-20 | 2014-12-08 | ノバルティス アーゲー | 小児の初回免疫のためのアジュバント添加インフルエンザｂウイルスワクチン |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2427213B1 (en) | 2015-04-01 |
| ES2537785T3 (es) | 2015-06-12 |
| EP2427213A4 (en) | 2013-08-21 |
| WO2010129947A3 (en) | 2011-03-10 |
| US8716012B2 (en) | 2014-05-06 |
| EP2427213A2 (en) | 2012-03-14 |
| JP2015134808A (ja) | 2015-07-27 |
| US20100285060A1 (en) | 2010-11-11 |
| CN102458470A (zh) | 2012-05-16 |
| CN102458470B (zh) | 2016-01-20 |
| WO2010129947A2 (en) | 2010-11-11 |
| JP5766894B2 (ja) | 2015-08-19 |
| HK1170669A1 (zh) | 2013-03-08 |
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