ES2533079T3 - Isomerización de 1-cloro-3,3,3-trifIuoropropeno - Google Patents

Isomerización de 1-cloro-3,3,3-trifIuoropropeno Download PDF

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Publication number
ES2533079T3
ES2533079T3 ES09832509.5T ES09832509T ES2533079T3 ES 2533079 T3 ES2533079 T3 ES 2533079T3 ES 09832509 T ES09832509 T ES 09832509T ES 2533079 T3 ES2533079 T3 ES 2533079T3
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ES
Spain
Prior art keywords
chloro
trifluoropropene
mixture
metal oxide
packing material
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Application number
ES09832509.5T
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English (en)
Spanish (es)
Inventor
Ryan Hulse
Rajiv R. Singh
Konstantin Pokrovski
Hsueh Sung Tung
Daniel Merkel
Haiyou Wang
Michael Van Der Puy
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Honeywell International Inc
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Honeywell International Inc
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Application filed by Honeywell International Inc filed Critical Honeywell International Inc
Application granted granted Critical
Publication of ES2533079T3 publication Critical patent/ES2533079T3/es
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/35Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C07C17/358Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction by isomerisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/02Alkenes
    • C07C11/10Alkenes with five carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/12Alkadienes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/12Alkadienes
    • C07C11/16Alkadienes with four carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/21Alkatrienes; Alkatetraenes; Other alkapolyenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/22Aliphatic unsaturated hydrocarbons containing carbon-to-carbon triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00Aliphatic unsaturated hydrocarbons
    • C07C11/28Aliphatic unsaturated hydrocarbons containing carbon-to-carbon double bonds and carbon-to-carbon triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C13/00Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/38Separation; Purification; Stabilisation; Use of additives
    • C07C17/383Separation; Purification; Stabilisation; Use of additives by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C21/00Acyclic unsaturated compounds containing halogen atoms
    • C07C21/02Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
    • C07C21/18Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds containing fluorine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
ES09832509.5T 2008-12-12 2009-12-10 Isomerización de 1-cloro-3,3,3-trifIuoropropeno Active ES2533079T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12221808P 2008-12-12 2008-12-12
US122218P 2008-12-12
US12/633,420 US8217208B2 (en) 2008-12-12 2009-12-08 Isomerization of 1-chloro-3,3,3-trifluoropropene
US633420 2009-12-08
PCT/US2009/067420 WO2010068715A2 (en) 2008-12-12 2009-12-10 Isomerization of 1-chloro-3,3,3-trifluoropropene

Publications (1)

Publication Number Publication Date
ES2533079T3 true ES2533079T3 (es) 2015-04-07

Family

ID=42241324

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09832509.5T Active ES2533079T3 (es) 2008-12-12 2009-12-10 Isomerización de 1-cloro-3,3,3-trifIuoropropeno

Country Status (9)

Country Link
US (1) US8217208B2 (https=)
EP (1) EP2379474B1 (https=)
JP (3) JP5745425B2 (https=)
KR (2) KR101839442B1 (https=)
CN (1) CN102245548B (https=)
CA (1) CA2746089C (https=)
ES (1) ES2533079T3 (https=)
MX (1) MX2011006010A (https=)
WO (1) WO2010068715A2 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2937328B1 (fr) 2008-10-16 2010-11-12 Arkema France Procede de transfert de chaleur
US8217208B2 (en) * 2008-12-12 2012-07-10 Honeywell International, Inc. Isomerization of 1-chloro-3,3,3-trifluoropropene
FR2962442B1 (fr) 2010-07-09 2016-02-26 Arkema France Composition stable de 2,3,3,3-tetrafluoropropene
US8704017B2 (en) * 2010-09-03 2014-04-22 Honeywell International Inc. Continuous low-temperature process to produce trans-1-chloro-3,3,3-trifluoropropene
US8378158B2 (en) * 2010-12-03 2013-02-19 Honeywell International Inc. Azeotrope-like compositions of (Z)-1-chloro-3,3,3-trifluoropropene and hydrogen fluoride
US9156752B2 (en) * 2011-01-04 2015-10-13 Honeywell International Inc. High purity E-1-chloro-3,3,3-trifluoropropene and methods of making the same
JP5750917B2 (ja) * 2011-02-01 2015-07-22 セントラル硝子株式会社 シス−1−クロロ−3,3,3−トリフルオロプロペンの製造方法
US8404907B2 (en) 2011-02-18 2013-03-26 Honeywell International Inc. Process for cis-1-chloro-3,3,3-trifluoropropene
US8653309B2 (en) * 2011-04-20 2014-02-18 Honeywell International Inc. Process for producing trans-1233zd
US8436217B2 (en) * 2011-04-25 2013-05-07 Honeywell International Inc. Integrated process to co-produce 1,1,1,3,3-pentafluoropropane, trans-1-chloro-3,3,3-trifluoropropene and trans-1,3,3,3-tetrafluoropropene
JP5834791B2 (ja) * 2011-11-11 2015-12-24 セントラル硝子株式会社 (e)−1−クロロ−3,3,3−トリフルオロプロペンの製造方法
JP5790438B2 (ja) * 2011-11-21 2015-10-07 セントラル硝子株式会社 トランス−1−クロロ−3,3,3−トリフルオロプロペンの製造方法
US8754272B2 (en) 2011-12-07 2014-06-17 Honeywell International Inc. Process for cis-1-chloro-3,3,3-trifluoropropene
US8653310B2 (en) * 2011-12-07 2014-02-18 Honeywell International Inc. Process for making cis-1-chloro-3,3,3-trifluoropropene
JP5899974B2 (ja) 2012-02-02 2016-04-06 セントラル硝子株式会社 (e)−1−クロロ−3,3,3−トリフルオロプロペンの製造方法
WO2013130342A1 (en) * 2012-03-02 2013-09-06 Arkema Inc. Process for the removal of contaminant from a hydrochlorofluoroolefin by extractive distillation
US9000239B2 (en) * 2012-05-15 2015-04-07 Honeywell International Inc. Methods for producing 1-chloro-3,3,3-trifluoropropene from 2-chloro-3,3,3-trifluoropropene
JP6156374B2 (ja) 2012-06-13 2017-07-05 セントラル硝子株式会社 1−クロロ−3,3,3−トリフルオロ−1−プロペン及び1,3,3,3−テトラフルオロプロペンの製造方法
US20140275644A1 (en) * 2013-03-14 2014-09-18 Honeywell International Inc. Method to produce cis-1-chloro-3,3,3-trifluoropropene
US9162947B2 (en) * 2013-03-15 2015-10-20 Honeywell International Inc. High temperature isomerization of (E)-1-chloro-3,3,3-trifluoropropene to (Z)-1-chloro-3,3,3-trifluoropropene
WO2015060407A1 (ja) 2013-10-25 2015-04-30 三菱重工業株式会社 冷媒循環装置、冷媒循環方法および酸抑制方法
JP6381890B2 (ja) * 2013-10-25 2018-08-29 三菱重工サーマルシステムズ株式会社 冷媒循環装置、冷媒循環方法および異性化抑制方法
CN106715669B (zh) 2014-10-02 2019-05-10 中央硝子株式会社 含有2-氯-1,3,3,3-四氟丙烯和1-氯-3,3,3-三氟丙烯的类共沸组合物
FR3033791B1 (fr) 2015-03-18 2017-04-14 Arkema France Stabilisation du 1-chloro-3,3,3-trifluoropropene
JP2016222647A (ja) * 2015-06-02 2016-12-28 セントラル硝子株式会社 ハイドロハロフルオロオレフィンの製造方法
WO2017002925A1 (ja) * 2015-06-30 2017-01-05 旭硝子株式会社 ヒドロクロロフルオロオレフィンの製造方法、および2,3,3,3-テトラフルオロプロペンの製造方法
CN109689604A (zh) * 2016-09-12 2019-04-26 Agc株式会社 1-氯-2,3,3-三氟丙烯的制造方法
US20190016652A1 (en) * 2017-07-12 2019-01-17 Honeywell International Inc. Systems and methods for manufacturing and separating (z)-1-chloro-3,3,3-trifluoropropene
FR3070982B1 (fr) 2017-09-12 2019-08-30 Arkema France Composition a base d'hydrochlorofluoroolefine et d'huile minerale
US9994502B1 (en) 2018-01-30 2018-06-12 Honeywell International Inc. Process for the production of 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd)
US10000431B1 (en) 2018-01-30 2018-06-19 Honeywell International Inc. Process for the production of 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd)
US10717662B2 (en) 2018-02-07 2020-07-21 Honeywell International Inc. Process for the removal of iron and phosphate ions from a chlorinated hydrocarbon waste stream
JP6753434B2 (ja) 2018-06-13 2020-09-09 ダイキン工業株式会社 ジフルオロエチレンの製造方法
FR3086287B1 (fr) * 2018-09-26 2020-09-18 Arkema France Stabilisation du 1-chloro-3,3,3-trifluoropropene
CN111925274B (zh) * 2020-09-17 2021-03-02 北京宇极科技发展有限公司 Z-1-氯-3,3,3-三氟丙烯的制备方法
WO2022138675A1 (ja) * 2020-12-22 2022-06-30 セントラル硝子株式会社 不飽和クロロフルオロカーボンの製造方法、及び組成物
CN112811975B (zh) * 2021-04-22 2021-07-30 泉州宇极新材料科技有限公司 气相异构化制备z-1-r-3,3,3-三氟丙烯的方法
US20260042722A1 (en) * 2024-08-07 2026-02-12 Honeywell International Inc. METHOD FOR PRODUCING ISOMERS OF 1,2-CHLORO-2,3,3-TRIFLUORO-1-PROPENE (HCFO-1233yd)

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE536296A (https=) 1954-03-22
IT535373A (https=) 1954-06-10
US2846458A (en) 1956-05-23 1958-08-05 Dow Corning Organosiloxane ethers
US2889379A (en) 1957-02-06 1959-06-02 Dow Chemical Co Preparation of 3, 3, 3-trifluoropropene
US4465786A (en) 1982-09-27 1984-08-14 General Electric Company Catalyst composition for the preparation of 3,3,3-trifluoropropene
US4761308A (en) 1987-06-22 1988-08-02 General Electric Company Process for the preparation of reflective pyrolytic graphite
US4798818A (en) 1987-11-27 1989-01-17 Dow Corning Corporation Catalyst composition and process for its preparation
WO1990012841A1 (en) 1989-04-24 1990-11-01 Huetzen Hans Wilhelm Polyurethane foam material free of halogenated hydrocarbons and process for producing the same
DE3933335C2 (de) 1989-10-06 1998-08-06 Basf Ag Verfahren zur Herstellung von Polyurethan-Hartschaumstoffen mit geringer Wärmeleitfähigkeit und ihre Verwendung
EP0431542A3 (en) 1989-12-07 1991-12-27 Hoechst Aktiengesellschaft Process for the preparation of foams
KR100240375B1 (ko) 1994-07-11 2000-01-15 크리스 로저 에이치 1,1,1,3,3-펜타플루오로프로판의 제조방법
US6111150A (en) 1996-06-20 2000-08-29 Central Glass Company, Limited Method for producing 1,1,1,3,3,-pentafluoropropane
US5710352A (en) * 1996-09-19 1998-01-20 Alliedsignal Inc. Vapor phase process for making 1,1,1,3,3-pentafluoropropane and 1-chloro-3,3,3-trifluoropropene
US5900185A (en) 1996-09-27 1999-05-04 University Of New Mexico Tropodegradable bromine-containing halocarbon additives to decrease flammability of refrigerants, foam blowing agents, solvents, aerosol propellants, and sterilants
JP3031465B2 (ja) * 1998-02-26 2000-04-10 セントラル硝子株式会社 1,1,1,3,3−ペンタフルオロプロパンの製造方法
BE1011765A3 (fr) 1998-02-26 2000-01-11 Solvay Procede d'hydrofluoration d'hydrocarbures.
EP0939071B1 (en) * 1998-02-26 2003-07-30 Central Glass Company, Limited Method for producing fluorinated propane
JP3031464B2 (ja) * 1998-02-26 2000-04-10 セントラル硝子株式会社 1,1,1,3,3−ペンタフルオロプロパンの製造方法
US6124510A (en) 1998-07-21 2000-09-26 Elf Atochem North America, Inc. 1234ze preparation
US6583328B1 (en) * 1999-04-05 2003-06-24 Pcbu Services, Inc. Method for the preparation of 1,1,1,3,3-pentafluoropropene and 1,1,1,3,3-pentafluoropropane
EP1317406B2 (en) 2000-08-10 2012-11-14 Solvay Sa Process for obtaining a purified hydrofluoroalkane
DE10103708A1 (de) 2001-01-26 2002-08-01 Basf Ag Thermische Isomerisierung von Lycopin
US9005467B2 (en) 2003-10-27 2015-04-14 Honeywell International Inc. Methods of replacing heat transfer fluids
US7230146B2 (en) 2003-10-27 2007-06-12 Honeywell International Inc. Process for producing fluoropropenes
US9796848B2 (en) 2002-10-25 2017-10-24 Honeywell International Inc. Foaming agents and compositions containing fluorine substituted olefins and methods of foaming
US8444874B2 (en) 2002-10-25 2013-05-21 Honeywell International Inc. Heat transfer methods using heat transfer compositions containing trans-1,3,3,3-tetrafluoropropene
US9255046B2 (en) * 2003-07-25 2016-02-09 Honeywell International Inc. Manufacturing process for HFO-1234ze
US7563936B2 (en) 2006-10-27 2009-07-21 Honeywell International Inc Processes for geometric isomerization of halogenated olefins
US6844475B1 (en) 2003-08-08 2005-01-18 Honeywell International Business Machines Low temperature production of 1-chloro-3,3,3-trifluoropropene (HCFC-1233zd)
JP4864878B2 (ja) * 2004-04-29 2012-02-01 ハネウェル・インターナショナル・インコーポレーテッド 1,3,3,3−テトラフルオロプロペンの合成法
US8084653B2 (en) 2004-04-29 2011-12-27 Honeywell International, Inc. Method for producing fluorinated organic compounds
US7659434B2 (en) 2004-04-29 2010-02-09 Honeywell International Inc. Method for producing fluorinated organic compounds
TW201742908A (zh) * 2005-06-24 2017-12-16 哈尼威爾國際公司 含有經氟取代之烯烴之組合物
TW201336906A (zh) 2005-06-24 2013-09-16 Honeywell Int Inc 含有經氟取代之烯烴之發泡劑及組合物,及發泡方法
JP4314391B2 (ja) * 2005-07-07 2009-08-12 独立行政法人産業技術総合研究所 フッ素化触媒とその製造方法及びそれら触媒を用いたフッ素化合物の製造方法
US20080007788A1 (en) 2006-06-30 2008-01-10 Good Frederick L Smart page photo sizing, composing and cropping tool
US7485760B2 (en) * 2006-08-24 2009-02-03 Honeywell International Inc. Integrated HFC trans-1234ze manufacture process
US8067650B2 (en) 2006-08-24 2011-11-29 Honeywell International Inc. Process for the production of HFO trans-1234ze from HFC-245fa
ES2607226T3 (es) * 2007-03-29 2017-03-29 Arkema Inc. Espuma de células cerradas y procedimiento
GB0706978D0 (en) * 2007-04-11 2007-05-16 Ineos Fluor Holdings Ltd Process
JP5380882B2 (ja) * 2007-04-17 2014-01-08 セントラル硝子株式会社 3,3,3−トリフルオロプロピンの製造方法
US7829747B2 (en) 2008-04-24 2010-11-09 Honeywell International Inc. Process for dehydrofluorination of 3-chloro-1,1,1,3-tetrafluoropropane to 1-chloro-3,3,3-trifluoropropene
CN105646135A (zh) * 2008-11-19 2016-06-08 阿科玛股份有限公司 用于制造氢氯氟烯烃的方法
US8217208B2 (en) * 2008-12-12 2012-07-10 Honeywell International, Inc. Isomerization of 1-chloro-3,3,3-trifluoropropene

Also Published As

Publication number Publication date
CN102245548A (zh) 2011-11-16
CN102245548B (zh) 2015-02-04
WO2010068715A4 (en) 2010-11-04
WO2010068715A3 (en) 2010-09-16
EP2379474B1 (en) 2015-01-14
US20100152504A1 (en) 2010-06-17
WO2010068715A2 (en) 2010-06-17
CA2746089C (en) 2019-11-26
MX2011006010A (es) 2011-07-13
JP5745425B2 (ja) 2015-07-08
JP2015110648A (ja) 2015-06-18
JP2017110020A (ja) 2017-06-22
KR20170007862A (ko) 2017-01-20
KR20110106363A (ko) 2011-09-28
JP2012512160A (ja) 2012-05-31
CA2746089A1 (en) 2010-06-17
US8217208B2 (en) 2012-07-10
JP6082765B2 (ja) 2017-02-15
KR101698482B1 (ko) 2017-01-20
KR101839442B1 (ko) 2018-03-16
EP2379474A4 (en) 2012-07-25
EP2379474A2 (en) 2011-10-26

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