ES2525826T3 - Maleato de 6-amino-2-{[(1s)-1-metilbutil]-oxi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-ona - Google Patents
Maleato de 6-amino-2-{[(1s)-1-metilbutil]-oxi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-ona Download PDFInfo
- Publication number
- ES2525826T3 ES2525826T3 ES11709025.8T ES11709025T ES2525826T3 ES 2525826 T3 ES2525826 T3 ES 2525826T3 ES 11709025 T ES11709025 T ES 11709025T ES 2525826 T3 ES2525826 T3 ES 2525826T3
- Authority
- ES
- Spain
- Prior art keywords
- purin
- oxy
- pentyl
- dihydro
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30301010P | 2010-02-10 | 2010-02-10 | |
| US303010P | 2010-02-10 | ||
| PCT/EP2011/051830 WO2011098452A1 (en) | 2010-02-10 | 2011-02-08 | 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2525826T3 true ES2525826T3 (es) | 2014-12-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11709025.8T Active ES2525826T3 (es) | 2010-02-10 | 2011-02-08 | Maleato de 6-amino-2-{[(1s)-1-metilbutil]-oxi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-ona |
Country Status (23)
Families Citing this family (22)
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| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| AU2009323766B2 (en) | 2008-12-02 | 2016-10-06 | Wave Life Sciences Ltd. | Method for the synthesis of phosphorus atom modified nucleic acids |
| SG177564A1 (en) | 2009-07-06 | 2012-02-28 | Ontorii Inc | Novel nucleic acid prodrugs and methods of use thereof |
| SI2491035T1 (sl) | 2009-10-22 | 2017-10-30 | Gilead Sciences, Inc. | Derivati purina ali deazapurina uporabni za zdravljenje (med drugimi) virusnih okužb |
| EP2620428B1 (en) | 2010-09-24 | 2019-05-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| US9605019B2 (en) | 2011-07-19 | 2017-03-28 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| SMT201800642T1 (it) * | 2011-07-22 | 2019-01-11 | Glaxosmithkline Llc | Composizione |
| JP6246121B2 (ja) * | 2012-07-13 | 2017-12-13 | 株式会社新日本科学 | キラル核酸アジュバント |
| SG10201912895PA (en) | 2012-07-13 | 2020-02-27 | Wave Life Sciences Ltd | Chiral control |
| JP6268157B2 (ja) | 2012-07-13 | 2018-01-24 | 株式会社Ｗａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｊａｐａｎ | 不斉補助基 |
| HK1211029A1 (en) | 2012-08-24 | 2016-05-13 | Glaxosmithkline Llc | Pyrazolopyrimidine compounds |
| EP2922547B1 (en) | 2012-11-20 | 2017-03-08 | Glaxosmithkline LLC | Novel compounds |
| AU2013348217B2 (en) | 2012-11-20 | 2016-10-06 | Glaxosmithkline Llc | Novel compounds |
| SMT201700378T1 (it) | 2012-11-20 | 2017-09-07 | Glaxosmithkline Llc | Nuovi composti |
| JPWO2015108048A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| JPWO2015108047A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| EP3095460A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| PT3094728T (pt) | 2014-01-16 | 2022-05-19 | Wave Life Sciences Ltd | Desenho quiral |
| WO2016033540A1 (en) * | 2014-08-29 | 2016-03-03 | Corium International, Inc. | Microstructure array for delivery of active agents |
| US10584125B2 (en) * | 2014-11-13 | 2020-03-10 | Glaxosmithkline Biologicals Sa | Adenine derivatives which are useful in the treatment of allergic diseases or other inflammatory conditions |
| US12130267B2 (en) * | 2018-11-28 | 2024-10-29 | Shimadzu Corporation | Analyzing method for azo compound |
| KR20250106231A (ko) | 2023-12-29 | 2025-07-09 | (주)셀트리온 | 안정한 약제학적 제제 |
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| BR0206614A (pt) | 2001-01-22 | 2004-02-17 | Merck & Co Inc | Composto, composição farmacêutica, método para inibir a polimerase viral de rna dependente de rna e/ou inibir a replicação viral de rna dependente de rna, método para tratar uma infecção viral de rna dependente de rna, e, uso de um composto |
| CA2441162A1 (en) | 2001-03-19 | 2002-09-26 | Ono Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising, as an active ingredient, triazaspiro[5.5]undecane derivative |
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| CA2448737C (en) | 2001-07-20 | 2010-06-01 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
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| GB0423673D0 (en) | 2004-10-25 | 2004-11-24 | Glaxo Group Ltd | Compounds |
| CN101247807A (zh) | 2005-05-09 | 2008-08-20 | 艾其林医药公司 | 噻唑化合物及使用方法 |
| JPWO2007034881A1 (ja) | 2005-09-22 | 2009-03-26 | 大日本住友製薬株式会社 | 新規アデニン化合物 |
| GB0610666D0 (en) | 2006-05-30 | 2006-07-05 | Glaxo Group Ltd | Fluid dispenser |
| ATE490249T1 (de) | 2007-02-19 | 2010-12-15 | Glaxosmithkline Llc | Purinderivate als immunmodulatoren |
| DK2132209T3 (da) * | 2007-03-19 | 2014-04-14 | Astrazeneca Ab | 9-substituerede 8-oxo-adeninforbindelser som modulatorer af tlr7 (toll-like receptor 7) |
| UY31531A1 (es) * | 2007-12-17 | 2009-08-03 | Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr) | |
| US8777708B2 (en) | 2008-06-27 | 2014-07-15 | Microsoft Corporation | Targeting control in a simulated environment |
| UA103195C2 (uk) * | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
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2011
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- 2011-02-08 JP JP2012552369A patent/JP5922587B2/ja active Active
- 2011-02-08 PL PL11709025T patent/PL2534149T3/pl unknown
- 2011-02-08 AU AU2011214468A patent/AU2011214468B2/en not_active Ceased
- 2011-02-08 KR KR1020127023687A patent/KR101773541B1/ko not_active Expired - Fee Related
- 2011-02-08 SG SG2012051140A patent/SG182471A1/en unknown
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- 2011-02-08 RS RS20150005A patent/RS53745B1/sr unknown
- 2011-02-08 ME MEP-2014-154A patent/ME01926B/me unknown
- 2011-02-08 ES ES11709025.8T patent/ES2525826T3/es active Active
- 2011-02-08 HR HRP20141258AT patent/HRP20141258T1/hr unknown
- 2011-02-08 WO PCT/EP2011/051830 patent/WO2011098452A1/en not_active Ceased
- 2011-02-08 CN CN201180009082.0A patent/CN102753553B/zh not_active Expired - Fee Related
- 2011-02-08 US US13/578,020 patent/US8703754B2/en not_active Expired - Fee Related
- 2011-02-08 EP EP11709025.8A patent/EP2534149B1/en active Active
- 2011-02-08 PT PT117090258T patent/PT2534149E/pt unknown
- 2011-02-08 EA EA201290631A patent/EA021048B1/ru not_active IP Right Cessation
- 2011-02-08 SI SI201130364T patent/SI2534149T1/sl unknown
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2534149A1 (en) | 2012-12-19 |
| EA021048B1 (ru) | 2015-03-31 |
| MX2012009316A (es) | 2012-09-12 |
| CN102753553A (zh) | 2012-10-24 |
| US8703754B2 (en) | 2014-04-22 |
| ME01926B (me) | 2015-05-20 |
| WO2011098452A1 (en) | 2011-08-18 |
| ZA201205995B (en) | 2014-01-29 |
| SG182471A1 (en) | 2012-08-30 |
| AU2011214468B2 (en) | 2015-05-28 |
| IL220845A (en) | 2016-08-31 |
| RS53745B1 (sr) | 2015-06-30 |
| HRP20141258T1 (hr) | 2015-02-27 |
| BR112012018904A2 (pt) | 2020-09-01 |
| DK2534149T3 (da) | 2015-01-05 |
| US20120308609A1 (en) | 2012-12-06 |
| PT2534149E (pt) | 2014-12-23 |
| SI2534149T1 (sl) | 2015-02-27 |
| SMT201400196B (it) | 2015-01-15 |
| AU2011214468A1 (en) | 2012-08-09 |
| EA201290631A1 (ru) | 2013-03-29 |
| KR101773541B1 (ko) | 2017-08-31 |
| JP2013519645A (ja) | 2013-05-30 |
| CA2786973A1 (en) | 2011-08-18 |
| CN102753553B (zh) | 2016-03-30 |
| EP2534149B1 (en) | 2014-10-15 |
| CA2786973C (en) | 2018-04-10 |
| JP5922587B2 (ja) | 2016-05-24 |
| KR20120135408A (ko) | 2012-12-13 |
| PL2534149T3 (pl) | 2015-03-31 |
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