ES2521515T3 - Compuestos cíclicos peptidomiméticos con giro beta para tratar el ojo seco - Google Patents
Compuestos cíclicos peptidomiméticos con giro beta para tratar el ojo seco Download PDFInfo
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- ES2521515T3 ES2521515T3 ES09726969.0T ES09726969T ES2521515T3 ES 2521515 T3 ES2521515 T3 ES 2521515T3 ES 09726969 T ES09726969 T ES 09726969T ES 2521515 T3 ES2521515 T3 ES 2521515T3
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- dry eye
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- C—CHEMISTRY; METALLURGY
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Landscapes
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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| US208873P | 2009-02-27 | ||
| PCT/US2009/002121 WO2009123761A1 (en) | 2008-04-04 | 2009-04-03 | Beta-turn peptidomimetic cyclic compounds for treating dry eye |
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| ES2521515T3 true ES2521515T3 (es) | 2014-11-12 |
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| CA (1) | CA2720141C (enExample) |
| ES (1) | ES2521515T3 (enExample) |
| WO (1) | WO2009123761A1 (enExample) |
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| EP2271337B1 (en) * | 2008-04-04 | 2014-09-03 | Mimetogen Pharmaceuticals Inc. | Beta-turn peptidomimetic cyclic compounds for treating dry eye |
| EP2864347B1 (en) * | 2012-06-22 | 2020-10-28 | Mimetogen Pharmaceuticals, Inc. | Synthesis of beta-turn peptidomimetic cyclic compounds |
| KR20150004652A (ko) | 2013-07-03 | 2015-01-13 | 삼성디스플레이 주식회사 | 표시 패널, 이를 포함하는 표시 장치 및 이를 이용하는 영상 표시 방법 |
| JP6267003B2 (ja) * | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤 |
| CN113230021A (zh) | 2015-01-12 | 2021-08-10 | 科达莱昂治疗公司 | 微滴递送设备和方法 |
| EP3253433A4 (en) | 2015-04-10 | 2018-08-22 | Kedalion Therapeutics, Inc. | Piezoelectric dispenser with replaceable ampoule |
| AU2016290654C1 (en) * | 2015-07-09 | 2021-11-11 | Mimetogen Pharmaceuticals, Inc. | Solution phase synthesis and crystallization of beta-turn peptidomimetic cyclic salts |
| KR101718733B1 (ko) | 2015-08-21 | 2017-03-22 | 국제약품 주식회사 | 레바미피드의 가용화 방법 및 이에 의해 제조된 안구건조증 치료용 액제 |
| CA3016546A1 (en) | 2016-03-04 | 2017-09-08 | James M. Rynerson | Method of treating an eye disorder by inhibiting or disrupting bacterial biofilm formation |
| JP7768665B2 (ja) | 2017-01-20 | 2025-11-12 | ボシュ ＋ ロム アイルランド リミテッド | 圧電流体ディスペンサ |
| CA3083219A1 (en) | 2017-12-08 | 2019-06-13 | Reynaldo Quintana | Fluid delivery alignment system |
| CN110092799B (zh) * | 2018-01-29 | 2021-11-12 | 广州丹康医药生物有限公司 | 一种环状化合物、其制备方法和应用 |
| US12350194B1 (en) | 2018-04-12 | 2025-07-08 | Bausch + Lomb Ireland Limited | Topical ocular delivery of fluids with controlled mass dosing and wireless communication |
| US20190314197A1 (en) | 2018-04-12 | 2019-10-17 | Kedalion Therapeutics, Inc. | Topical Ocular Delivery Methods and Devices for Use in the Same |
| KR102827233B1 (ko) | 2018-07-03 | 2025-06-30 | 보슈 롬 아일랜드 리미티드 | 국소 안구 전달 디바이스들 및 이를 사용하기 위한 방법들 |
| US12097145B2 (en) | 2019-03-06 | 2024-09-24 | Bausch + Lomb Ireland Limited | Vented multi-dose ocular fluid delivery system |
| US11679028B2 (en) | 2019-03-06 | 2023-06-20 | Novartis Ag | Multi-dose ocular fluid delivery system |
| US12496218B1 (en) | 2019-11-12 | 2025-12-16 | Bausch + Lomb Ireland Limited | Fractionated topical ocular drug delivery methods and devices for use in the same |
| WO2021212038A1 (en) | 2020-04-17 | 2021-10-21 | Kedalion Therapeutics, Inc. | Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir |
| JP7711090B2 (ja) | 2020-04-17 | 2025-07-22 | ボシュ ＋ ロム アイルランド リミテッド | 流体力学的に起動される防腐剤無添加分注システム |
| US11938057B2 (en) | 2020-04-17 | 2024-03-26 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| US12290472B2 (en) | 2020-04-17 | 2025-05-06 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| CA3221772A1 (en) * | 2021-06-02 | 2022-12-08 | Kevin Burgess | Selective small molecule agonists and partial agonists of trk receptors |
| CA3234071A1 (en) * | 2021-10-20 | 2023-04-27 | Stealth Biotherapeutics Inc. | Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions |
| WO2023069255A1 (en) * | 2021-10-20 | 2023-04-27 | Stealth Biotherapeutics Inc. | Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions |
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| GB8917217D0 (en) * | 1989-07-27 | 1989-09-13 | Smith & Nephew | Ophthalmic compositions |
| US5545617A (en) * | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
| EP1041996A4 (en) * | 1997-12-22 | 2003-05-14 | Human Genome Sciences Inc | KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS |
| JP2001064198A (ja) | 1999-08-24 | 2001-03-13 | Teika Seiyaku Kk | 角膜疾患治療剤 |
| EP1265605B1 (en) * | 2000-01-18 | 2006-09-27 | McGILL UNIVERSITY | Pharmaceutical compositions comprising beta-turn peptidomimetic cyclic compounds |
| ATE423135T1 (de) * | 2005-06-13 | 2009-03-15 | Primm Srl | Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten |
| EP1921087A1 (en) | 2006-11-10 | 2008-05-14 | Primm S.R.L. | Process for the preparation of cyclic peptides |
| JP5576659B2 (ja) * | 2006-12-05 | 2014-08-20 | ザ ロイヤル インスティテューション フォー ジ アドバンスメント オブ ラーニング／ マギル ユニバーシティ | Ｔｒｋレセプター調節因子の使用方法 |
| EP2271337B1 (en) | 2008-04-04 | 2014-09-03 | Mimetogen Pharmaceuticals Inc. | Beta-turn peptidomimetic cyclic compounds for treating dry eye |
| ES2512717T3 (es) * | 2009-02-27 | 2014-10-24 | Mimetogen Pharmaceuticals Inc. | Compuestos cíclicos peptidomiméticos para el tratamiento de la retinitis pigmentosa |
| EP2864347B1 (en) * | 2012-06-22 | 2020-10-28 | Mimetogen Pharmaceuticals, Inc. | Synthesis of beta-turn peptidomimetic cyclic compounds |
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2009
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- 2009-04-03 CN CN2009801190689A patent/CN102046166B/zh active Active
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- 2009-04-03 WO PCT/US2009/002121 patent/WO2009123761A1/en not_active Ceased
- 2009-04-03 CA CA2720141A patent/CA2720141C/en active Active
- 2009-04-03 JP JP2011502992A patent/JP5480242B2/ja active Active
- 2009-04-03 AU AU2009232352A patent/AU2009232352B2/en active Active
- 2009-04-03 US US12/935,217 patent/US8293713B2/en active Active
- 2009-04-03 KR KR1020107024714A patent/KR101565185B1/ko active Active
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2012
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2014
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- 2014-05-29 US US14/290,845 patent/US9156882B2/en active Active
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Also Published As
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| JP2014080447A (ja) | 2014-05-08 |
| US20140274910A1 (en) | 2014-09-18 |
| HK1152898A1 (en) | 2012-03-16 |
| US20160082072A1 (en) | 2016-03-24 |
| EP2271337B1 (en) | 2014-09-03 |
| JP5870348B2 (ja) | 2016-02-24 |
| US20110105410A1 (en) | 2011-05-05 |
| US9156882B2 (en) | 2015-10-13 |
| US9707267B2 (en) | 2017-07-18 |
| KR101565185B1 (ko) | 2015-11-02 |
| CA2720141C (en) | 2014-01-28 |
| KR20110010712A (ko) | 2011-02-07 |
| US20120322747A1 (en) | 2012-12-20 |
| WO2009123761A1 (en) | 2009-10-08 |
| US8293713B2 (en) | 2012-10-23 |
| AU2009232352A1 (en) | 2009-10-08 |
| US8748391B2 (en) | 2014-06-10 |
| AU2009232352B2 (en) | 2013-09-05 |
| CN102046166A (zh) | 2011-05-04 |
| JP5480242B2 (ja) | 2014-04-23 |
| CA2720141A1 (en) | 2009-10-08 |
| JP2011516477A (ja) | 2011-05-26 |
| EP2271337A1 (en) | 2011-01-12 |
| CN102046166B (zh) | 2012-10-17 |
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