ES2435403T3 - Tratamiento de trastornos del sueño y vigilia - Google Patents
Tratamiento de trastornos del sueño y vigilia Download PDFInfo
- Publication number
- ES2435403T3 ES2435403T3 ES06772647T ES06772647T ES2435403T3 ES 2435403 T3 ES2435403 T3 ES 2435403T3 ES 06772647 T ES06772647 T ES 06772647T ES 06772647 T ES06772647 T ES 06772647T ES 2435403 T3 ES2435403 T3 ES 2435403T3
- Authority
- ES
- Spain
- Prior art keywords
- enantiomer
- formula
- group
- use according
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68863805P | 2005-06-08 | 2005-06-08 | |
| US688638P | 2005-06-08 | ||
| PCT/US2006/022407 WO2006133393A1 (en) | 2005-06-08 | 2006-06-07 | Treatment of sleep-wake disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2435403T3 true ES2435403T3 (es) | 2013-12-19 |
Family
ID=37085728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06772647T Active ES2435403T3 (es) | 2005-06-08 | 2006-06-07 | Tratamiento de trastornos del sueño y vigilia |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US8440715B2 (2) |
| EP (1) | EP1890684B1 (2) |
| JP (1) | JP5024635B2 (2) |
| KR (1) | KR101335941B1 (2) |
| CN (1) | CN101217949B (2) |
| AU (1) | AU2006254899B2 (2) |
| BE (1) | BE2020C004I2 (2) |
| BR (1) | BRPI0613697A2 (2) |
| CA (1) | CA2611713C (2) |
| DK (1) | DK1890684T3 (2) |
| ES (1) | ES2435403T3 (2) |
| FR (1) | FR20C1014I2 (2) |
| NL (1) | NL301037I2 (2) |
| PL (1) | PL1890684T3 (2) |
| RU (1) | RU2417077C2 (2) |
| TW (2) | TW201328689A (2) |
| WO (1) | WO2006133393A1 (2) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1890684B1 (en) | 2005-06-08 | 2013-08-14 | SK Biopharmaceuticals Co., Ltd. | Treatment of sleep-wake disorders |
| ES2344469T3 (es) * | 2005-06-22 | 2010-08-27 | Sk Holdings Co., Ltd. | Tratamiento de disfuncion sexual. |
| KR20120098578A (ko) | 2009-06-22 | 2012-09-05 | 에스케이바이오팜 주식회사 | 피로의 치료 또는 예방 방법 |
| US8232315B2 (en) * | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| BR112012010670A2 (pt) | 2009-11-06 | 2016-04-12 | Sk Biopharmaceuticals Co Ltd | métodos para tratamento de distúrbio de défict de atenção/hiperatividade |
| EP2496227B1 (en) * | 2009-11-06 | 2019-05-22 | SK Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
| US9610274B2 (en) * | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| US8623913B2 (en) * | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| CA2905457A1 (en) * | 2013-03-13 | 2014-10-09 | Aerial Biopharma, Llc | Treatment of cataplexy |
| CA2917702A1 (en) | 2013-07-18 | 2015-01-22 | Jazz Pharmaceuticals International Iii Limited | Treatment for obesity |
| US10888542B2 (en) | 2014-02-28 | 2021-01-12 | Sk Biopharmaceuticals Co., Ltd. | Aminocarbonylcarbamate compounds |
| TWI698415B (zh) * | 2014-02-28 | 2020-07-11 | 南韓商愛思開生物製藥股份有限公司 | 胺基羰基胺基甲酸酯化合物 |
| WO2016061488A1 (en) * | 2014-10-17 | 2016-04-21 | Concert Pharmaceuticals, Inc. | Amine reuptake inhibitors |
| JP6466792B2 (ja) * | 2015-07-03 | 2019-02-06 | エスケー バイオファーマスティカルズ カンパニー リミテッド | 注意欠陥／多動性障害（ａｄｈｄ）の治療方法 |
| TWI637765B (zh) * | 2016-05-10 | 2018-10-11 | 台灣共振波研發股份有限公司 | Soothing device for attention deficit hyperactivity disorder |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| MY197630A (en) | 2016-09-06 | 2023-06-29 | Sk Biopharmaceuticals Co Ltd | Solvate form of (r)-2-amino-3-phenylpropyl carbamate |
| ES2964943T3 (es) | 2016-10-06 | 2024-04-10 | Axsome Malta Ltd | Compuestos de carbamoilfenilalaninol para uso médico |
| BR112019025286A2 (pt) | 2017-06-02 | 2020-06-23 | Jazz Pharmaceuticals Ireland Limited | Métodos e composições para tratamento de sonolência excessiva |
| JP7366002B2 (ja) * | 2017-07-31 | 2023-10-20 | ジャズ ファーマシューティカルズ アイルランド リミテッド | カルバモイルフェニルアラニノール類縁体およびその使用 |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
| US11033214B1 (en) * | 2020-05-19 | 2021-06-15 | United Arab Emirates University | Wearable eye tracking system |
| KR102390194B1 (ko) * | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
| AU2023375326A1 (en) * | 2022-11-07 | 2025-05-22 | Axsome Therapeutics | Compositions and methods for treating insomnia |
| EP4626417A1 (en) * | 2022-11-30 | 2025-10-08 | Axsome Therapeutics | Methods and compositions for improving driving performance |
| KR20260033050A (ko) | 2023-06-29 | 2026-03-10 | 액섬 테라퓨틱스, 인크. | 수유 여성에게 솔리암페톨을 투여하는 방법 |
| WO2025165760A1 (en) * | 2024-01-29 | 2025-08-07 | Axsome Therapeutics, Inc. | Phenylalkylamino carbamates for use in the treatment of attention deficit/hyperactivity disorder |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2939660A1 (de) | 1979-09-29 | 1981-04-16 | Basf Ag, 6700 Ludwigshafen | Neue carbamate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| NZ260667A (en) | 1993-06-10 | 1997-05-26 | Lilly Co Eli | Preventing emesis or treating sexual dysfunction using tetrahydrobenz[cd]indole 6-carboxamides |
| KR100197892B1 (ko) * | 1994-09-09 | 1999-06-15 | 남창우 | 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법 |
| US5756817C1 (en) * | 1995-02-11 | 2001-04-17 | Sk Corp | O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same |
| KR0173862B1 (ko) | 1995-02-11 | 1999-04-01 | 조규향 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| KR0173863B1 (ko) | 1995-04-10 | 1999-04-01 | 조규향 | 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| DK0873308T3 (da) * | 1996-10-10 | 2002-04-22 | Sk Corp | O-Carbamoyl-phenylalaninol-forbindelser og deres farmaceutisk anvendelige salte |
| AU4674797A (en) | 1996-10-22 | 1998-05-15 | Ortho Pharmaceutical Corporation | Phenylalaninol derivatives for the treatment of central nervous system disorders |
| PT1411917E (pt) | 2001-02-27 | 2007-09-17 | Ortho Mcneil Pharm Inc | ''compostos carbamatos para utilização na prevenção ou tratamento de distúrbios do movimento'' |
| IL157594A0 (en) | 2001-02-27 | 2004-03-28 | Ortho Mcneil Pharm Inc | Carbamate compounds for use in preventing or treating anxiety disorders |
| ES2262801T3 (es) | 2001-02-27 | 2006-12-01 | Ortho-Mcneil Pharmaceutical, Inc. | Uso de un compuesto de carbamato para la prevencion o el tratamiento de trastorno bipolar. |
| US20050080268A1 (en) | 2003-10-08 | 2005-04-14 | Yong-Moon Choi | Process of preparing O-carbamoyl compounds in the presence of active amine group |
| US20050203130A1 (en) | 2003-12-02 | 2005-09-15 | Erik Buntinx | Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists |
| RU2007119648A (ru) | 2004-10-28 | 2008-12-10 | СК Холдингз Ко. | Способ лечения депрессии |
| EP1890684B1 (en) * | 2005-06-08 | 2013-08-14 | SK Biopharmaceuticals Co., Ltd. | Treatment of sleep-wake disorders |
| ES2344469T3 (es) | 2005-06-22 | 2010-08-27 | Sk Holdings Co., Ltd. | Tratamiento de disfuncion sexual. |
| ES2385087T3 (es) | 2005-07-26 | 2012-07-18 | Sk Biopharmaceuticals Co., Ltd | Procedimientos para tratar trastornos relacionados con sustancias |
| BRPI0719275A2 (pt) | 2006-10-13 | 2014-04-29 | Janssen Pharmaceutica Nv | Composições de carbamatos de fenil-alquil-amino |
| KR20120098578A (ko) | 2009-06-22 | 2012-09-05 | 에스케이바이오팜 주식회사 | 피로의 치료 또는 예방 방법 |
| US8232315B2 (en) | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| EP2496227B1 (en) | 2009-11-06 | 2019-05-22 | SK Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
| BR112012010670A2 (pt) | 2009-11-06 | 2016-04-12 | Sk Biopharmaceuticals Co Ltd | métodos para tratamento de distúrbio de défict de atenção/hiperatividade |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| KR102005483B1 (ko) | 2012-10-19 | 2019-07-31 | 삼성디스플레이 주식회사 | 박막 트랜지스터 기판 및 그의 수리 방법 |
| CA2905457A1 (en) * | 2013-03-13 | 2014-10-09 | Aerial Biopharma, Llc | Treatment of cataplexy |
-
2006
- 2006-06-07 EP EP06772647.1A patent/EP1890684B1/en active Active
- 2006-06-07 KR KR1020087000522A patent/KR101335941B1/ko active Active
- 2006-06-07 BR BRPI0613697-4A patent/BRPI0613697A2/pt not_active Application Discontinuation
- 2006-06-07 CN CN2006800253545A patent/CN101217949B/zh active Active
- 2006-06-07 TW TW101130937A patent/TW201328689A/zh unknown
- 2006-06-07 US US11/921,995 patent/US8440715B2/en active Active
- 2006-06-07 PL PL06772647T patent/PL1890684T3/pl unknown
- 2006-06-07 JP JP2008515949A patent/JP5024635B2/ja active Active
- 2006-06-07 CA CA2611713A patent/CA2611713C/en not_active Expired - Fee Related
- 2006-06-07 DK DK06772647.1T patent/DK1890684T3/da active
- 2006-06-07 WO PCT/US2006/022407 patent/WO2006133393A1/en not_active Ceased
- 2006-06-07 ES ES06772647T patent/ES2435403T3/es active Active
- 2006-06-07 TW TW095120134A patent/TWI419681B/zh active
- 2006-06-07 RU RU2008100019/15A patent/RU2417077C2/ru active
- 2006-06-07 AU AU2006254899A patent/AU2006254899B2/en active Active
-
2013
- 2013-01-23 US US13/747,508 patent/US8877806B2/en active Active
-
2014
- 2014-08-06 US US14/452,816 patent/US9604917B2/en active Active
-
2017
- 2017-02-15 US US15/433,660 patent/US10351517B2/en active Active
-
2019
- 2019-05-23 US US16/420,834 patent/US20190367448A1/en not_active Abandoned
-
2020
- 2020-03-30 NL NL301037C patent/NL301037I2/nl unknown
- 2020-04-16 FR FR20C1014C patent/FR20C1014I2/fr active Active
- 2020-05-07 BE BE2020C004C patent/BE2020C004I2/nl unknown
- 2020-09-28 US US17/034,564 patent/US11753368B2/en active Active
-
2023
- 2023-08-03 US US18/364,689 patent/US12209059B2/en active Active
-
2024
- 2024-12-13 US US18/979,843 patent/US20250109099A1/en active Pending
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