ES2393833T3 - Procedimiento de producir un agente de contraste hiperpolarizado - Google Patents

Procedimiento de producir un agente de contraste hiperpolarizado Download PDF

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Publication number
ES2393833T3
ES2393833T3 ES09009608T ES09009608T ES2393833T3 ES 2393833 T3 ES2393833 T3 ES 2393833T3 ES 09009608 T ES09009608 T ES 09009608T ES 09009608 T ES09009608 T ES 09009608T ES 2393833 T3 ES2393833 T3 ES 2393833T3
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ES
Spain
Prior art keywords
agent
polarization
contrast agent
solid
omri contrast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09009608T
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English (en)
Spanish (es)
Inventor
Jan Henrik Ardenkjaer-Larsen
Oskar Axelsson
Klaes Golman
Georg Hansson
Ib Leunbach
Stefan Petersson
Lars-Göran Wistrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9800158.9A external-priority patent/GB9800158D0/en
Priority claimed from GBGB9813795.3A external-priority patent/GB9813795D0/en
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Application granted granted Critical
Publication of ES2393833T3 publication Critical patent/ES2393833T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Magnetic Ceramics (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
ES09009608T 1998-01-05 1998-12-23 Procedimiento de producir un agente de contraste hiperpolarizado Expired - Lifetime ES2393833T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9800158.9A GB9800158D0 (en) 1998-01-05 1998-01-05 Method
GB9800158 1998-01-05
GB9813795 1998-06-25
GBGB9813795.3A GB9813795D0 (en) 1998-06-25 1998-06-25 Method

Publications (1)

Publication Number Publication Date
ES2393833T3 true ES2393833T3 (es) 2012-12-28

Family

ID=26312888

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09009608T Expired - Lifetime ES2393833T3 (es) 1998-01-05 1998-12-23 Procedimiento de producir un agente de contraste hiperpolarizado

Country Status (15)

Country Link
US (2) US6278893B1 (cg-RX-API-DMAC7.html)
EP (2) EP2119457B1 (cg-RX-API-DMAC7.html)
JP (1) JP4764548B2 (cg-RX-API-DMAC7.html)
KR (1) KR100699396B1 (cg-RX-API-DMAC7.html)
CN (2) CN1138154C (cg-RX-API-DMAC7.html)
AU (1) AU752308C (cg-RX-API-DMAC7.html)
BR (1) BRPI9813244B1 (cg-RX-API-DMAC7.html)
CA (1) CA2317526C (cg-RX-API-DMAC7.html)
ES (1) ES2393833T3 (cg-RX-API-DMAC7.html)
HU (1) HU229718B1 (cg-RX-API-DMAC7.html)
IL (1) IL136780A0 (cg-RX-API-DMAC7.html)
NO (1) NO334035B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ505151A (cg-RX-API-DMAC7.html)
RU (1) RU2221255C2 (cg-RX-API-DMAC7.html)
WO (1) WO1999035508A1 (cg-RX-API-DMAC7.html)

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