PL1824523T3 - Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu - Google Patents

Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu

Info

Publication number
PL1824523T3
PL1824523T3 PL05816233T PL05816233T PL1824523T3 PL 1824523 T3 PL1824523 T3 PL 1824523T3 PL 05816233 T PL05816233 T PL 05816233T PL 05816233 T PL05816233 T PL 05816233T PL 1824523 T3 PL1824523 T3 PL 1824523T3
Authority
PL
Poland
Prior art keywords
hyperpolarized
pyruvate
cardiac imaging
cardiac
imaging
Prior art date
Application number
PL05816233T
Other languages
English (en)
Inventor
Mathilde Lerche
René Zandt
Klaes Golman
Mikkel Thaning
Jan-Henrik Ardenkjær-Larsen
Stefan Petersson
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of PL1824523T3 publication Critical patent/PL1824523T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
PL05816233T 2004-11-19 2005-11-18 Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu PL1824523T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20045058 2004-11-19
EP05816233.0A EP1824523B1 (en) 2004-11-19 2005-11-18 Method of cardiac imaging with the use of hyperpolarized 13c-pyruvate
PCT/NO2005/000434 WO2006054903A2 (en) 2004-11-19 2005-11-18 Method of cardiac imaging with the use of hyperpolarized 13 c-pyruvate

Publications (1)

Publication Number Publication Date
PL1824523T3 true PL1824523T3 (pl) 2013-12-31

Family

ID=36182402

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05816233T PL1824523T3 (pl) 2004-11-19 2005-11-18 Sposób obrazowania serca przy zastosowaniu hiperspolaryzowanego 13C-pirogronianu

Country Status (13)

Country Link
US (1) US8980224B2 (pl)
EP (1) EP1824523B1 (pl)
JP (1) JP5456256B2 (pl)
KR (1) KR101249634B1 (pl)
CN (1) CN101102799B (pl)
AU (1) AU2005307194B2 (pl)
BR (1) BRPI0518302A2 (pl)
CA (1) CA2587795C (pl)
ES (1) ES2422558T3 (pl)
MX (1) MX2007006048A (pl)
PL (1) PL1824523T3 (pl)
RU (1) RU2391047C2 (pl)
WO (1) WO2006054903A2 (pl)

Families Citing this family (30)

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JP5102221B2 (ja) * 2005-12-16 2012-12-19 ジーイー・ヘルスケア・アクスイェ・セルスカプ 過分極カルボン酸塩の製造方法
US7202665B1 (en) * 2006-04-19 2007-04-10 Wisconsin Alumni Research Foundation Magnetic resonance spectroscopy of species with multiple peaks
US7754913B2 (en) 2006-07-11 2010-07-13 Cambridge Isotope Laboratories, Inc. Synthesis of isotopically labeled alpha-keto acids and esters
US20100178249A1 (en) * 2006-08-18 2010-07-15 Brindle Kevin M Imaging medium comprising lactate and hyperpolarised 13c-pyruvate
ES2381380T3 (es) * 2006-08-18 2012-05-25 Ge Healthcare As Formación de imagenes de 13C-RM o de espectroscopia de muerte celular
EP2057131B1 (en) 2006-08-30 2013-08-21 Ge Healthcare As Method of dynamic nuclear polarisation (dnp) and compounds and compositions for use in the method
AU2007322450A1 (en) * 2006-11-21 2008-05-29 Ge Healthcare As Method for managing patients with cancers
WO2008086534A1 (en) 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
US8483798B2 (en) * 2007-01-15 2013-07-09 General Electric Company System and method for metabolic MR imaging of a hyperpolarized agent
US11224635B2 (en) 2007-03-27 2022-01-18 Venturis Thereuptics, Inc. Therapeutic angiogenesis for treatment of the spine and other tissues
US8983570B2 (en) * 2007-03-27 2015-03-17 Cardiovascular Biotherapeutics, Inc. Therapeutic angiogenesis for treatment of the spine
US7470813B2 (en) 2007-03-30 2008-12-30 Ge Healthcare Limited Method for the production of pyruvic acid
KR20150053819A (ko) * 2007-05-17 2015-05-18 제너럴 일렉트릭 캄파니 과분극화 １３ｃ－피루베이트를 포함하는 영상화 매질을 사용하여 종양을 등급화하는 ｍｒ 방법
GB0713074D0 (en) 2007-07-05 2007-08-15 Univ London A method of hyperpolarising a magnetic resonance agent
US20100196283A1 (en) * 2007-07-26 2010-08-05 Lerche Matilde H Method and imaging medium for use in the method
EP2183591A1 (en) * 2007-09-07 2010-05-12 GE Healthcare UK Limited Method of determination of pdh activity and imaging media for use in said method
EP2902041A1 (en) 2007-12-19 2015-08-05 GE Healthcare Limited Composition and method for generating a metabolic profile using 13C-MR detection
WO2009129265A1 (en) 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
JP2011519554A (ja) 2008-05-02 2011-07-14 ゼネラル・エレクトリック・カンパニイ 過分極１３ｃ−ピルビン酸塩を用いた１３ｃ−ｍｒ検出によるアラニントランスアミナーゼ（ａｌｔ）活性の測定方法
KR101666239B1 (ko) 2009-04-02 2016-10-13 지이 헬쓰케어 리미티드 염증 또는 감염의 검출을 위한 과분극화 １３ｃ 피루베이트를 포함하는 자기 공명 영상화 매질의 용도
SG10201405591YA (en) * 2009-09-10 2014-10-30 Ge Healthcare Ltd 13c-mr detection using hyperpolarised 13c-fructose
EP2343568A1 (en) * 2009-12-30 2011-07-13 Koninklijke Philips Electronics N.V. Dynamic nuclear polarization apparatus with sample transport system
RU2547755C2 (ru) * 2010-02-22 2015-04-10 Конинклейке Филипс Электроникс Н.В. Rf антенное устройство и способ восстановления многоядерного mr изображения, включающий в себя параллельную mri
WO2012145733A1 (en) 2011-04-22 2012-10-26 Vanderbilt University Para-hydrogen polarizer
US9381257B2 (en) * 2012-07-13 2016-07-05 Bracco Imaging S.P.A. Triarylmethyl radicals
US9874622B2 (en) 2013-09-27 2018-01-23 General Electric Company Hyperpolarized media transport vessel
KR101516634B1 (ko) * 2014-07-09 2015-05-06 연세대학교 산학협력단 13c-자기공명분광영상을 이용한 암 환자의 치료 예후를 예측하는 방법
RU2622983C1 (ru) * 2016-07-25 2017-06-21 федеральное государственное бюджетное образовательное учреждение высшего образования "Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ интраоперационной визуализации ишемически-реперфузионного повреждения миокарда
WO2019159154A1 (en) * 2018-02-19 2019-08-22 Bruker France Sas Nuclear spin hyperpolarization in a porous matrix
US11350888B2 (en) * 2019-09-03 2022-06-07 Siemens Healthcare Gmbh Risk prediction for sudden cardiac death from image derived cardiac motion and structure features

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5597548A (en) * 1990-07-18 1997-01-28 Board Of Regents, The University Of Texas System 13 C Isotopomer analyses in intact tissue using (13 C) homonuclear decoupling
EP0951650B1 (en) * 1997-01-08 2003-12-10 Amersham Health AS Method of magnetic resonance imaging
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US6958244B2 (en) * 2002-04-12 2005-10-25 Bruker Biospin Corp. Low-conductivity buffers for magnetic resonance measurements

Also Published As

Publication number Publication date
AU2005307194B2 (en) 2011-02-10
EP1824523A2 (en) 2007-08-29
BRPI0518302A2 (pt) 2008-11-11
RU2391047C2 (ru) 2010-06-10
JP5456256B2 (ja) 2014-03-26
US20090162287A1 (en) 2009-06-25
ES2422558T3 (es) 2013-09-12
EP1824523B1 (en) 2013-05-01
CA2587795C (en) 2015-01-20
CN101102799B (zh) 2011-05-04
KR101249634B1 (ko) 2013-04-01
JP2008520335A (ja) 2008-06-19
CN101102799A (zh) 2008-01-09
AU2005307194A1 (en) 2006-05-26
MX2007006048A (es) 2007-07-25
WO2006054903A3 (en) 2007-03-15
KR20070089171A (ko) 2007-08-30
WO2006054903A2 (en) 2006-05-26
RU2007118383A (ru) 2008-12-27
CA2587795A1 (en) 2006-05-26
US8980224B2 (en) 2015-03-17

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