ES2384979T3 - Procedimiento para preparar compuestos de polietilenglicol - Google Patents

Procedimiento para preparar compuestos de polietilenglicol Download PDF

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Publication number
ES2384979T3
ES2384979T3 ES05798703T ES05798703T ES2384979T3 ES 2384979 T3 ES2384979 T3 ES 2384979T3 ES 05798703 T ES05798703 T ES 05798703T ES 05798703 T ES05798703 T ES 05798703T ES 2384979 T3 ES2384979 T3 ES 2384979T3
Authority
ES
Spain
Prior art keywords
polyethylene glycol
reaction mixture
compound
substituted
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES05798703T
Other languages
English (en)
Spanish (es)
Inventor
Edward D. Daugs
Robert Bruce Appell
Jeffrey G. Hippler
Brian T. Keen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories EU Ltd
Original Assignee
Dr Reddys Laboratories EU Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories EU Ltd filed Critical Dr Reddys Laboratories EU Ltd
Application granted granted Critical
Publication of ES2384979T3 publication Critical patent/ES2384979T3/es
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES05798703T 2004-09-28 2005-09-27 Procedimiento para preparar compuestos de polietilenglicol Active ES2384979T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US952198 2001-09-13
US10/952,198 US7199193B2 (en) 2004-09-28 2004-09-28 Polyethylene glycol compounds and process of making
PCT/US2005/034251 WO2006036825A1 (en) 2004-09-28 2005-09-27 Polyethylene glycol compounds and process for making

Publications (1)

Publication Number Publication Date
ES2384979T3 true ES2384979T3 (es) 2012-07-16

Family

ID=35432615

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05798703T Active ES2384979T3 (es) 2004-09-28 2005-09-27 Procedimiento para preparar compuestos de polietilenglicol

Country Status (8)

Country Link
US (2) US7199193B2 (enExample)
EP (1) EP1797131B1 (enExample)
JP (1) JP4987719B2 (enExample)
KR (1) KR101279664B1 (enExample)
CN (1) CN101031604B (enExample)
AT (1) ATE552286T1 (enExample)
ES (1) ES2384979T3 (enExample)
WO (1) WO2006036825A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004059489C5 (de) † 2004-12-10 2011-12-08 Clariant Produkte (Deutschland) Gmbh Verfahren zur Herstellung von reinen alpha-Alkoxy-omega-hydroxy-Polyalkylenglykolen
US20100172996A1 (en) * 2007-05-29 2010-07-08 Youl Chon Chemical Co., Ltd. Chain-End Functionalized Methoxy Poly(Ethylene Glycol) and Metal Nano-Particles Using the Same
TWI451876B (zh) 2008-06-13 2014-09-11 Lilly Co Eli 聚乙二醇化之離脯胰島素化合物
EP2348064B1 (en) * 2008-11-11 2013-08-07 NOF Corporation Method for producing polyalkylene glycol derivatives
JP5713274B2 (ja) * 2009-03-31 2015-05-07 日油株式会社 高分子量ポリオキシアルキレン誘導体の精製方法
JP5569787B2 (ja) * 2009-03-31 2014-08-13 日油株式会社 高分子量ポリエチレングリコール化合物の精製方法
EP2275470B1 (de) 2009-06-18 2012-02-15 Basf Se Verfahren zur Herstellung von Monohydroxypolyalkylenoxiden
CN104169327A (zh) * 2012-04-18 2014-11-26 旭硝子株式会社 聚醚类的制造方法
JP2016513082A (ja) 2013-01-28 2016-05-12 ニューヨーク・ユニバーシティ 無毒性神経毒誘導体を用いる治療方法
JP6106104B2 (ja) * 2014-01-16 2017-03-29 信越化学工業株式会社 末端にアミノ基を有する狭分散ポリアルキレングリコール誘導体の製造方法
US9708350B2 (en) 2014-12-04 2017-07-18 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator
JP6460937B2 (ja) 2014-12-04 2019-01-30 信越化学工業株式会社 末端にアミノ基を有するポリアルキレングリコール誘導体の製造方法
US10377775B2 (en) 2014-12-04 2019-08-13 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end
EP3230457B1 (en) 2014-12-09 2021-06-30 New York University Clostridial neurotoxin fusion proteins, propeptide fusions, their expression, and use
US11254787B2 (en) * 2017-08-17 2022-02-22 Sabic Global Technologies B.V. Method of preparing fatty acid monoester of polyoxyethylene, ester made therewith, and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911926A (en) 1988-11-16 1990-03-27 Mediventures Inc. Method and composition for reducing postsurgical adhesions
US6280745B1 (en) 1997-12-23 2001-08-28 Alliance Pharmaceutical Corp. Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
US6455639B1 (en) 1998-03-24 2002-09-24 Nof Corporation Oxirane derivative and process for the preparation thereof
JP3050228B2 (ja) * 1998-03-24 2000-06-12 日本油脂株式会社 オキシラン誘導体及びその製造方法
DE10121807A1 (de) * 2001-05-04 2002-11-07 Bayer Ag Verfahren zur Herstellung von Polyetherpolyolen
ATE460451T1 (de) 2003-07-22 2010-03-15 Nektar Therapeutics Verfahren zur herstellung von funktionalisierten polymeren aus polymeralkoholen

Also Published As

Publication number Publication date
CN101031604A (zh) 2007-09-05
US20070213479A1 (en) 2007-09-13
EP1797131A1 (en) 2007-06-20
EP1797131B1 (en) 2012-04-04
ATE552286T1 (de) 2012-04-15
US7199193B2 (en) 2007-04-03
WO2006036825A1 (en) 2006-04-06
JP2008514763A (ja) 2008-05-08
KR20070058534A (ko) 2007-06-08
CN101031604B (zh) 2010-08-11
JP4987719B2 (ja) 2012-07-25
US20060074200A1 (en) 2006-04-06
KR101279664B1 (ko) 2013-06-27

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