ES2357623T5 - Dispositivos oftálmicos para la liberación sostenida de compuestos activos - Google Patents
Dispositivos oftálmicos para la liberación sostenida de compuestos activos Download PDFInfo
- Publication number
- ES2357623T5 ES2357623T5 ES06742806.0T ES06742806T ES2357623T5 ES 2357623 T5 ES2357623 T5 ES 2357623T5 ES 06742806 T ES06742806 T ES 06742806T ES 2357623 T5 ES2357623 T5 ES 2357623T5
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- Prior art keywords
- contact lens
- prepolymer
- crosslinkable
- host substance
- lens
- Prior art date
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- 229920001721 polyimide Polymers 0.000 description 1
- 239000003505 polymerization initiator Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000001448 refractive index detection Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- FVEFRICMTUKAML-UHFFFAOYSA-M sodium tetradecyl sulfate Chemical compound [Na+].CCCCC(CC)CCC(CC(C)C)OS([O-])(=O)=O FVEFRICMTUKAML-UHFFFAOYSA-M 0.000 description 1
- BWYYYTVSBPRQCN-UHFFFAOYSA-M sodium;ethenesulfonate Chemical group [Na+].[O-]S(=O)(=O)C=C BWYYYTVSBPRQCN-UHFFFAOYSA-M 0.000 description 1
- JJMIAJGBZGZNHA-UHFFFAOYSA-N sodium;styrene Chemical group [Na].C=CC1=CC=CC=C1 JJMIAJGBZGZNHA-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 229920006301 statistical copolymer Polymers 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 125000004213 tert-butoxy group Chemical group [H]C([H])([H])C(O*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
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- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00865—Applying coatings; tinting; colouring
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Eyeglasses (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67796405P | 2005-05-05 | 2005-05-05 | |
| US677964P | 2005-05-05 | ||
| US71987805P | 2005-09-23 | 2005-09-23 | |
| US719878P | 2005-09-23 | ||
| PCT/EP2006/004193 WO2006117228A2 (en) | 2005-05-05 | 2006-05-04 | Ophthalmic devices for sustained delivery of active compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2357623T3 ES2357623T3 (es) | 2011-04-28 |
| ES2357623T5 true ES2357623T5 (es) | 2016-03-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES06742806.0T Active ES2357623T5 (es) | 2005-05-05 | 2006-05-04 | Dispositivos oftálmicos para la liberación sostenida de compuestos activos |
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| Country | Link |
|---|---|
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| EP (1) | EP1886169B2 (enExample) |
| JP (1) | JP5053261B2 (enExample) |
| CN (1) | CN101171531B (enExample) |
| AR (1) | AR055931A1 (enExample) |
| AT (1) | ATE493679T2 (enExample) |
| AU (1) | AU2006243345B2 (enExample) |
| BR (1) | BRPI0611434A2 (enExample) |
| CA (1) | CA2606073C (enExample) |
| DE (1) | DE602006019234D1 (enExample) |
| DK (1) | DK1886169T4 (enExample) |
| ES (1) | ES2357623T5 (enExample) |
| MX (1) | MX2007013739A (enExample) |
| NO (1) | NO340948B1 (enExample) |
| PL (1) | PL1886169T5 (enExample) |
| PT (1) | PT1886169E (enExample) |
| TW (1) | TWI375571B (enExample) |
| WO (1) | WO2006117228A2 (enExample) |
| ZA (1) | ZA200708953B (enExample) |
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| US20080152540A1 (en) * | 2006-12-22 | 2008-06-26 | Bausch & Lomb Incorporated | Packaging solutions |
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| TWI551305B (zh) | 2007-08-31 | 2016-10-01 | 諾華公司 | 相對黏稠封裝溶液之用途 |
| US20090182068A1 (en) * | 2008-01-14 | 2009-07-16 | Yuwen Liu | Polymerizable Contact Lens Formulations and Contact Lenses Obtained Therefrom |
| JP4869274B2 (ja) * | 2008-03-21 | 2012-02-08 | 株式会社メニコン | ソフトコンタクトレンズ包装製品及びソフトコンタクトレンズの包装方法 |
| EP2307189B1 (en) | 2008-07-21 | 2014-06-04 | Novartis AG | Silicone hydrogel contact lenses with convertible comfort agents |
| US20100106128A1 (en) * | 2008-10-23 | 2010-04-29 | Shane Mao | Contact lens cases for delivery of ophthalmic agents |
| TWI506333B (zh) * | 2008-12-05 | 2015-11-01 | Novartis Ag | 用以傳遞疏水性舒適劑之眼用裝置及其製造方法 |
| AU2012268828B2 (en) * | 2008-12-05 | 2013-09-05 | Alcon Inc. | Ophthalmic devices for delivery of hydrophobic comfort agents |
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| ES2634551T3 (es) * | 2010-04-03 | 2017-09-28 | Praful Doshi | Métodos para revestir una lente de contacto |
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| US9827250B2 (en) * | 2012-07-31 | 2017-11-28 | Johnson & Johnson Vision Care, Inc. | Lens incorporating myopia control optics and muscarinic agents |
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| HUE063934T2 (hu) | 2015-12-17 | 2024-02-28 | Alcon Inc | Újrahasználható lencseszerszámok, valamint eljárások azok használatára |
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| JP7518773B2 (ja) * | 2019-02-12 | 2024-07-18 | 株式会社クラレ | ポリマー組成物、ゲル、フィルムおよび粒子 |
| JP7704740B2 (ja) | 2019-09-16 | 2025-07-08 | アムジエン・インコーポレーテツド | 薬物送達デバイスの外部滅菌の方法 |
| KR20220034199A (ko) * | 2019-09-18 | 2022-03-17 | 알콘 인코포레이티드 | 습식-패킹 소프트 하이드로겔 안구 삽입물 |
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-
2006
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- 2006-05-03 AR ARP060101787A patent/AR055931A1/es active IP Right Grant
- 2006-05-03 TW TW095115677A patent/TWI375571B/zh active
- 2006-05-04 WO PCT/EP2006/004193 patent/WO2006117228A2/en not_active Ceased
- 2006-05-04 PL PL06742806T patent/PL1886169T5/pl unknown
- 2006-05-04 ES ES06742806.0T patent/ES2357623T5/es active Active
- 2006-05-04 AU AU2006243345A patent/AU2006243345B2/en active Active
- 2006-05-04 DK DK06742806.0T patent/DK1886169T4/en active
- 2006-05-04 EP EP06742806.0A patent/EP1886169B2/en active Active
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- 2006-05-04 CN CN2006800152347A patent/CN101171531B/zh active Active
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- 2006-05-04 MX MX2007013739A patent/MX2007013739A/es active IP Right Grant
- 2006-05-04 PT PT06742806T patent/PT1886169E/pt unknown
- 2006-05-04 BR BRPI0611434-2A patent/BRPI0611434A2/pt not_active Application Discontinuation
- 2006-05-04 JP JP2008509385A patent/JP5053261B2/ja active Active
-
2007
- 2007-10-18 ZA ZA200708953A patent/ZA200708953B/xx unknown
- 2007-12-04 NO NO20076252A patent/NO340948B1/no not_active IP Right Cessation
-
2017
- 2017-07-11 US US15/646,617 patent/US20170307780A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0611434A2 (pt) | 2010-09-08 |
| CN101171531A (zh) | 2008-04-30 |
| CN101171531B (zh) | 2010-06-16 |
| MX2007013739A (es) | 2008-01-21 |
| DK1886169T4 (en) | 2016-03-14 |
| AR055931A1 (es) | 2007-09-12 |
| ZA200708953B (en) | 2008-06-25 |
| WO2006117228A2 (en) | 2006-11-09 |
| PL1886169T3 (pl) | 2011-05-31 |
| EP1886169B2 (en) | 2015-12-09 |
| EP1886169B1 (en) | 2010-12-29 |
| US20060251696A1 (en) | 2006-11-09 |
| CA2606073C (en) | 2013-12-03 |
| AU2006243345A1 (en) | 2006-11-09 |
| AU2006243345B2 (en) | 2010-03-18 |
| DE602006019234D1 (de) | 2011-02-10 |
| TW200716201A (en) | 2007-05-01 |
| US9804295B2 (en) | 2017-10-31 |
| WO2006117228A3 (en) | 2007-02-01 |
| JP5053261B2 (ja) | 2012-10-17 |
| DK1886169T3 (da) | 2011-03-14 |
| JP2008539837A (ja) | 2008-11-20 |
| CA2606073A1 (en) | 2006-11-09 |
| TWI375571B (en) | 2012-11-01 |
| ES2357623T3 (es) | 2011-04-28 |
| EP1886169A2 (en) | 2008-02-13 |
| PT1886169E (pt) | 2011-03-07 |
| NO340948B1 (no) | 2017-07-24 |
| PL1886169T5 (pl) | 2016-05-31 |
| US20170307780A1 (en) | 2017-10-26 |
| NO20076252L (no) | 2008-02-05 |
| ATE493679T2 (de) | 2011-01-15 |
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