ES2355388T3 - Métodos para la detección precoz de cáncer. - Google Patents

Métodos para la detección precoz de cáncer. Download PDF

Info

Publication number
ES2355388T3
ES2355388T3 ES07706065T ES07706065T ES2355388T3 ES 2355388 T3 ES2355388 T3 ES 2355388T3 ES 07706065 T ES07706065 T ES 07706065T ES 07706065 T ES07706065 T ES 07706065T ES 2355388 T3 ES2355388 T3 ES 2355388T3
Authority
ES
Spain
Prior art keywords
cancer
sample
cells
protein
malignant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07706065T
Other languages
English (en)
Spanish (es)
Inventor
Nadir Arber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEDICAL RES FUND OF TEL AVIV SOURASKY MEDICAL CT
MEDICAL RESEARCH FUND OF TEL AVIV SOURASKY MEDICAL CENTER
Original Assignee
MEDICAL RES FUND OF TEL AVIV SOURASKY MEDICAL CT
MEDICAL RESEARCH FUND OF TEL AVIV SOURASKY MEDICAL CENTER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDICAL RES FUND OF TEL AVIV SOURASKY MEDICAL CT, MEDICAL RESEARCH FUND OF TEL AVIV SOURASKY MEDICAL CENTER filed Critical MEDICAL RES FUND OF TEL AVIV SOURASKY MEDICAL CT
Application granted granted Critical
Publication of ES2355388T3 publication Critical patent/ES2355388T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES07706065T 2006-01-31 2007-01-31 Métodos para la detección precoz de cáncer. Active ES2355388T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76337806P 2006-01-31 2006-01-31
US763378P 2006-01-31

Publications (1)

Publication Number Publication Date
ES2355388T3 true ES2355388T3 (es) 2011-03-25

Family

ID=38001788

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07706065T Active ES2355388T3 (es) 2006-01-31 2007-01-31 Métodos para la detección precoz de cáncer.

Country Status (12)

Country Link
US (1) US9394569B2 (https=)
EP (1) EP1994410B1 (https=)
JP (1) JP5091163B2 (https=)
AT (1) ATE486285T1 (https=)
DE (1) DE602007010108D1 (https=)
DK (1) DK1994410T3 (https=)
ES (1) ES2355388T3 (https=)
IL (1) IL193097A (https=)
PL (1) PL1994410T3 (https=)
PT (1) PT1994410E (https=)
SI (1) SI1994410T1 (https=)
WO (1) WO2007088537A2 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486285T1 (de) 2006-01-31 2010-11-15 Medical Res Fund Of Tel Aviv S Verfahren zur früherkennung von krebs
WO2009074988A1 (en) * 2007-12-10 2009-06-18 Medical Research Fund Of Tel Aviv Sourasky Medical Center Methods of diagnosing cancer
EP2358912B1 (en) * 2008-10-30 2016-10-12 Caris Life Sciences Switzerland Holdings GmbH Methods for assessing rna patterns
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
GB2463401B (en) * 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
US20140148348A1 (en) 2010-01-13 2014-05-29 Christine Kuslich Dectection of gastrointestinal disorders
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
AU2011256064B2 (en) 2010-05-21 2016-09-15 The Governors Of The University Of Alberta Methods for the assessment of colorectal cancer and colorectal polyps by measurement of metabolites in urine
EP3052651B1 (en) 2013-10-01 2019-11-27 Life Technologies Corporation Systems and methods for detecting structural variants
ES2939298T3 (es) 2017-05-21 2023-04-20 Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct Combinación de marcadores para el diagnóstico del cáncer
EP3447154A1 (en) * 2017-08-23 2019-02-27 Instytut Genetyki Sadowej Jolanta Powierska - Czarny Method for detection of mutations, polymorphisms and specific dna sequences on dna matrices with dna imaging techniques for the use in medical diagnostics and forensic genetics
US20200408761A1 (en) 2018-02-28 2020-12-31 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
JP7462632B2 (ja) 2018-11-30 2024-04-05 カリス エムピーアイ インコーポレイテッド 次世代分子プロファイリング
CN110777213A (zh) * 2019-11-05 2020-02-11 武汉科技大学 一种潜伏期胃癌诊断试剂盒
WO2021112918A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor
US11840720B2 (en) 2019-12-23 2023-12-12 Metabolomic Technologies Inc. Urinary metabolomic biomarkers for detecting colorectal cancer and polyps

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500411A (ja) * 1991-02-05 1995-01-12 ファロク セィディ 癌胎児性抗原を検出するための簡易検査法
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US7081516B2 (en) * 2002-08-26 2006-07-25 Case Western Reserve University Methods for categorizing patients
EP1497642A2 (en) * 2002-03-19 2005-01-19 Tularik, Inc. Gene amplification in cancer
US20040097448A1 (en) * 2002-11-19 2004-05-20 Isis Pharmaceuticals Inc. Modulation of CD24 expression
WO2005024603A2 (en) * 2003-09-10 2005-03-17 The Board Of Regents Of The University Of Texas System Methods for detecting, diagnosing and treating human renal cell carcinoma
CA2549913A1 (en) * 2003-11-26 2005-06-16 The Ohio State University Research Foundation Polymorphic cd24 genotypes that are predictive of multiple sclerosis risk and progression
CA2453198A1 (en) * 2004-01-07 2005-07-07 Wei-Ping Min Quantification and generation of immune suppressive exosomes
US7666583B2 (en) * 2004-02-19 2010-02-23 Yale University Identification of cancer protein biomarkers using proteomic techniques
ATE486285T1 (de) 2006-01-31 2010-11-15 Medical Res Fund Of Tel Aviv S Verfahren zur früherkennung von krebs

Also Published As

Publication number Publication date
IL193097A0 (en) 2009-02-11
EP1994410B1 (en) 2010-10-27
JP5091163B2 (ja) 2012-12-05
US9394569B2 (en) 2016-07-19
SI1994410T1 (sl) 2011-03-31
PL1994410T3 (pl) 2011-12-30
WO2007088537A2 (en) 2007-08-09
JP2009525041A (ja) 2009-07-09
DK1994410T3 (da) 2011-01-31
IL193097A (en) 2013-03-24
DE602007010108D1 (https=) 2010-12-09
US20100062450A1 (en) 2010-03-11
ATE486285T1 (de) 2010-11-15
WO2007088537A3 (en) 2007-10-25
EP1994410A2 (en) 2008-11-26
PT1994410E (pt) 2011-01-10

Similar Documents

Publication Publication Date Title
ES2355388T3 (es) Métodos para la detección precoz de cáncer.
Hlavata et al. The role of ABC transporters in progression and clinical outcome of colorectal cancer
ES2700877T3 (es) Fosfodiesterasa 4D7 como marcador de cáncer de próstata
ES2744244T3 (es) Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata usando c-MAF
ES2300176B1 (es) Metodo para el diagnostico molecular de cancer de prostata, kit para implementar el metodo.
KR102047502B1 (ko) 포타슘 채널 단백질을 이용한 암 진단용 조성물
US11022612B2 (en) BARD1 isoforms in lung and colorectal cancer and use thereof
US9034587B2 (en) Methods of diagnosing cancer
ES2861440T3 (es) Uso de complejos del factor de transcripción de nucleosomas para la detección del cáncer
US20140186837A1 (en) Methods For Diagnosing Cancer
WO2014198995A1 (es) Biomarcadores para el diagnóstico y respuesta al tratamiento en cáncer de páncreas
Mohajertehran et al. Overexpression of high-mobility motor box 1 in the blood and tissues of patients with head and neck squamous cell carcinoma
ES2906203T3 (es) Variante de CIP2A novedosa y usos de la misma
KR101388711B1 (ko) 암 진단 마커로서의 보체 c9
Smith et al. Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study
KR101058753B1 (ko) 대장암 마커로서의 esm-1 유전자 및 이를 이용한대장암의 진단 및 치료에의 용도
KR101289454B1 (ko) 소세포폐암 및 비소세포폐암 진단 마커로서의 보체 c9
US20150004621A1 (en) Biological marker for early cancer detection and methods for cancer detection (bf819)
US7759068B2 (en) Use of substances for treating tumors
TWI757285B (zh) 癌症偵測方法
Pavlovich et al. Prostate Cancer Detection by Molecular Urinalysis
GB2515530A (en) Method