ATE486285T1 - Verfahren zur früherkennung von krebs - Google Patents

Verfahren zur früherkennung von krebs

Info

Publication number
ATE486285T1
ATE486285T1 AT07706065T AT07706065T ATE486285T1 AT E486285 T1 ATE486285 T1 AT E486285T1 AT 07706065 T AT07706065 T AT 07706065T AT 07706065 T AT07706065 T AT 07706065T AT E486285 T1 ATE486285 T1 AT E486285T1
Authority
AT
Austria
Prior art keywords
cancer
determining
kits
subject
methods
Prior art date
Application number
AT07706065T
Other languages
English (en)
Inventor
Nadir Arber
Original Assignee
Medical Res Fund Of Tel Aviv S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Fund Of Tel Aviv S filed Critical Medical Res Fund Of Tel Aviv S
Application granted granted Critical
Publication of ATE486285T1 publication Critical patent/ATE486285T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT07706065T 2006-01-31 2007-01-31 Verfahren zur früherkennung von krebs ATE486285T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76337806P 2006-01-31 2006-01-31
PCT/IL2007/000122 WO2007088537A2 (en) 2006-01-31 2007-01-31 Methods and kits for early detection of cancer or predisposition thereto

Publications (1)

Publication Number Publication Date
ATE486285T1 true ATE486285T1 (de) 2010-11-15

Family

ID=38001788

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07706065T ATE486285T1 (de) 2006-01-31 2007-01-31 Verfahren zur früherkennung von krebs

Country Status (12)

Country Link
US (1) US9394569B2 (de)
EP (1) EP1994410B1 (de)
JP (1) JP5091163B2 (de)
AT (1) ATE486285T1 (de)
DE (1) DE602007010108D1 (de)
DK (1) DK1994410T3 (de)
ES (1) ES2355388T3 (de)
IL (1) IL193097A (de)
PL (1) PL1994410T3 (de)
PT (1) PT1994410E (de)
SI (1) SI1994410T1 (de)
WO (1) WO2007088537A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394569B2 (en) 2006-01-31 2016-07-19 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and kits for early detection of cancer or predisposition thereto
WO2009074988A1 (en) * 2007-12-10 2009-06-18 Medical Research Fund Of Tel Aviv Sourasky Medical Center Methods of diagnosing cancer
CN102308004A (zh) * 2008-10-30 2012-01-04 卡里斯生命科学卢森堡控股有限责任公司 评价rna图案的方法
CA2743211A1 (en) * 2008-11-12 2010-05-20 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Methods and systems of using exosomes for determining phenotypes
AU2011205230A1 (en) 2010-01-13 2012-08-02 Caris Life Sciences Switzerland Holdings Gmbh Detection of gastrointestinal disorders
US9128101B2 (en) 2010-03-01 2015-09-08 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
AU2011256064B2 (en) 2010-05-21 2016-09-15 The Governors Of The University Of Alberta Methods for the assessment of colorectal cancer and colorectal polyps by measurement of metabolites in urine
WO2015050919A1 (en) 2013-10-01 2015-04-09 Life Technologies Corporation Systems and methods for detecting structural variants
EP3652541B1 (de) * 2017-05-21 2022-12-14 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Kombination von markern zur diagnose von krebs
EP3447154A1 (de) * 2017-08-23 2019-02-27 Instytut Genetyki Sadowej Jolanta Powierska - Czarny Verfahren zur detektion von mutationen, polymorphismen und spezifischen dna-sequenzen auf dna-matrizen mit dna-bildgebungstechniken zur verwendung in der medizinischen diagnostik und forensischen genetik
US20200408761A1 (en) 2018-02-28 2020-12-31 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
WO2020113237A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
CN110777213A (zh) * 2019-11-05 2020-02-11 武汉科技大学 一种潜伏期胃癌诊断试剂盒
KR20260043144A (ko) 2019-12-02 2026-03-31 캐리스 엠피아이, 아이엔씨. 범-암 백금 반응 예측기
US11840720B2 (en) 2019-12-23 2023-12-12 Metabolomic Technologies Inc. Urinary metabolomic biomarkers for detecting colorectal cancer and polyps

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0571539A4 (en) * 1991-02-05 1994-06-29 Kamal Bahar Simple test for detecting carcinoembryonic antigen
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US7081516B2 (en) * 2002-08-26 2006-07-25 Case Western Reserve University Methods for categorizing patients
US6974672B2 (en) * 2002-03-19 2005-12-13 Amgen Inc. Gene amplification in cancer
US20040097448A1 (en) * 2002-11-19 2004-05-20 Isis Pharmaceuticals Inc. Modulation of CD24 expression
US20050130193A1 (en) * 2003-09-10 2005-06-16 Luxon Bruce A. Methods for detecting, diagnosing and treating human renal cell carcinoma
CA2549913A1 (en) * 2003-11-26 2005-06-16 The Ohio State University Research Foundation Polymorphic cd24 genotypes that are predictive of multiple sclerosis risk and progression
CA2453198A1 (en) 2004-01-07 2005-07-07 Wei-Ping Min Quantification and generation of immune suppressive exosomes
JP4912894B2 (ja) * 2004-02-19 2012-04-11 イェール ユニバーシティー プロテオーム技術を使用した癌タンパク質バイオマーカーの同定
US9394569B2 (en) 2006-01-31 2016-07-19 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and kits for early detection of cancer or predisposition thereto

Also Published As

Publication number Publication date
US20100062450A1 (en) 2010-03-11
PL1994410T3 (pl) 2011-12-30
IL193097A (en) 2013-03-24
US9394569B2 (en) 2016-07-19
WO2007088537A3 (en) 2007-10-25
JP2009525041A (ja) 2009-07-09
EP1994410B1 (de) 2010-10-27
DK1994410T3 (da) 2011-01-31
EP1994410A2 (de) 2008-11-26
SI1994410T1 (sl) 2011-03-31
WO2007088537A2 (en) 2007-08-09
DE602007010108D1 (de) 2010-12-09
PT1994410E (pt) 2011-01-10
ES2355388T3 (es) 2011-03-25
JP5091163B2 (ja) 2012-12-05
IL193097A0 (en) 2009-02-11

Similar Documents

Publication Publication Date Title
DK1994410T3 (da) Fremgangsmåder og kits til tidlig påvisning af cancer eller disposition derfor
BRPI0607508A2 (pt) métodos e ácidos nucléicos para análise de distúrbios proliferativos celulares
WO2010005991A3 (en) Circulating tumor and tumor stem cell detection using genomic specific probes
WO2008146309A3 (en) Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
WO2010056337A3 (en) Methods and systems of using exosomes for determining phenotypes
WO2013022995A3 (en) Biomarker compositions and methods
WO2007089911A3 (en) Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject
WO2012174282A3 (en) Biomarker compositions and methods
WO2010033371A3 (en) Molecular markers for lung and colorectal carcinomas
ATE522627T1 (de) Verfahren zur herstellung von nukleinsäuresonden
WO2009047756A3 (en) Methods and kits for diagnosing lung cancer
WO2013134786A3 (en) Biomarker compositions and methods
RU2013146242A (ru) Fgfr и его лиганды в качестве биомаркеров рака молочной железы у hr-положительных индивидуумов
MX2010010465A (es) Metodo para la deteccion de igf1r/chr 15 en celulas tumorales circulantes mediante hibridacion fluorescente in situ.
TW200643175A (en) Markers for prenatal diagnosis and monitoring
MX2009005651A (es) Marcadores geneticos para el manejo de riesgo de la arritmia cardiaca.
ATE488604T1 (de) System zum nachweis von polynukleotiden
EA200970695A1 (ru) Способы и нуклеиновые кислоты для анализов нарушений клеточной пролиферации
WO2008140463A3 (en) Biomarker panels for assessing radiation injury and exposure
BRPI0919882A8 (pt) Métodos para avaliar padrões de rna
WO2010020619A3 (en) Susceptibility to dasatinib
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
ATE555214T1 (de) Verfahren zur diagnose proliferativer erkrankungen durch detektion von genmethylierung
WO2006026074A3 (en) Atherosclerotic phenotype determinative genes and methods for using the same
ATE408712T1 (de) Verfahren zur bestimmung des wiederauftretens von prostata krebs

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1994410

Country of ref document: EP