EA200970695A1 - Способы и нуклеиновые кислоты для анализов нарушений клеточной пролиферации - Google Patents

Способы и нуклеиновые кислоты для анализов нарушений клеточной пролиферации

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Publication number
EA200970695A1
EA200970695A1 EA200970695A EA200970695A EA200970695A1 EA 200970695 A1 EA200970695 A1 EA 200970695A1 EA 200970695 A EA200970695 A EA 200970695A EA 200970695 A EA200970695 A EA 200970695A EA 200970695 A1 EA200970695 A1 EA 200970695A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nucleic acids
analysis
methods
cell proliferation
proliferation disorders
Prior art date
Application number
EA200970695A
Other languages
English (en)
Other versions
EA018010B1 (ru
Inventor
Фолькер Либенберг
Юрген Дистлер
Йорн Левин
Фабиан Модель
Раймо Тетцнер
Рене Кортезе
Original Assignee
Эпигеномикс Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эпигеномикс Аг filed Critical Эпигеномикс Аг
Publication of EA200970695A1 publication Critical patent/EA200970695A1/ru
Publication of EA018010B1 publication Critical patent/EA018010B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

Изобретение относится к способам, нуклеиновым кислотам и наборам для обнаружения нарушений клеточной пролиферации. Изобретение раскрывает геномные последовательности, профили метилирования которых применимы для улучшенного обнаружения указанного нарушения, посредством чего обеспечивается более эффективная диагностика и лечение пациентов.
EA200970695A 2007-01-19 2008-01-18 Способы и нуклеиновые кислоты для анализов нарушений клеточной пролиферации EA018010B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07100829 2007-01-19
EP07110019 2007-06-11
EP07113449 2007-07-30
PCT/EP2008/000384 WO2008087040A2 (en) 2007-01-19 2008-01-18 Methods and nucleic acids for analyses of cell proliferative disorders

Publications (2)

Publication Number Publication Date
EA200970695A1 true EA200970695A1 (ru) 2010-02-26
EA018010B1 EA018010B1 (ru) 2013-04-30

Family

ID=39430717

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970695A EA018010B1 (ru) 2007-01-19 2008-01-18 Способы и нуклеиновые кислоты для анализов нарушений клеточной пролиферации

Country Status (15)

Country Link
EP (2) EP2115165B1 (ru)
JP (2) JP5342456B2 (ru)
AT (1) ATE549418T1 (ru)
AU (1) AU2008207110B2 (ru)
CA (2) CA2675895C (ru)
CY (1) CY1115439T1 (ru)
DK (1) DK2258871T3 (ru)
EA (1) EA018010B1 (ru)
ES (2) ES2486190T3 (ru)
HR (1) HRP20140692T1 (ru)
IL (2) IL199894A (ru)
PL (1) PL2258871T3 (ru)
PT (1) PT2258871E (ru)
SI (1) SI2258871T1 (ru)
WO (1) WO2008087040A2 (ru)

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CA2675895C (en) * 2007-01-19 2016-03-22 Epigenomics Ag Methods and nucleic acids for analyses of cell proliferative disorders
US8399193B2 (en) * 2007-08-30 2013-03-19 City Of Hope DNA methylation biomarkers for lung cancer
EP2302069A1 (en) * 2007-12-11 2011-03-30 Epigenomics AG Methods and nucleic acids for analyses of cell proliferative disorders
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AR077238A1 (es) * 2009-06-26 2011-08-10 Unilever Nv Composiciones para el cuidado bucal. uso de un polimero para fabricar la composicion
AU2012212148B8 (en) 2011-02-02 2017-07-06 University Of Washington Through Its Center For Commercialization Massively parallel contiguity mapping
JP2013074837A (ja) * 2011-09-30 2013-04-25 Sumitomo Chemical Co Ltd 哺乳動物由来の検体の癌化度を評価する方法
EP2970951B1 (en) 2013-03-13 2019-02-20 Illumina, Inc. Methods for nucleic acid sequencing
EP3083994B1 (en) 2013-12-20 2021-08-18 Illumina, Inc. Preserving genomic connectivity information in fragmented genomic dna samples
US11873480B2 (en) * 2014-10-17 2024-01-16 Illumina Cambridge Limited Contiguity preserving transposition
US10604759B2 (en) 2016-01-15 2020-03-31 City Of Hope Targeting glioblastoma stem cells through the TLX-TET3 axis
CN106222080A (zh) * 2016-08-12 2016-12-14 深圳市天元印科技有限公司 肺癌预测系统
US20220193113A1 (en) 2019-05-31 2022-06-23 Osaka University Novel therapeutic agent for gastrointestinal cancer and method for screening for the same
JP7469771B1 (ja) 2023-12-13 2024-04-17 １７Ｌｉｖｅ株式会社 サーバおよび方法

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Also Published As

Publication number Publication date
CA2675895A1 (en) 2008-07-24
JP5818374B2 (ja) 2015-11-18
PT2258871E (pt) 2014-08-27
WO2008087040A2 (en) 2008-07-24
CA2675895C (en) 2016-03-22
CA2921557A1 (en) 2008-07-24
JP2010516234A (ja) 2010-05-20
CY1115439T1 (el) 2017-01-04
JP5342456B2 (ja) 2013-11-13
ES2486190T3 (es) 2014-08-18
ATE549418T1 (de) 2012-03-15
IL233548A (en) 2015-07-30
EA018010B1 (ru) 2013-04-30
DK2258871T3 (da) 2014-08-11
AU2008207110A2 (en) 2009-09-03
IL199894A0 (en) 2010-04-15
ES2384071T3 (es) 2012-06-29
JP2013150611A (ja) 2013-08-08
CA2921557C (en) 2022-02-08
AU2008207110A1 (en) 2008-07-24
EP2115165A2 (en) 2009-11-11
EP2115165B1 (en) 2012-03-14
AU2008207110B2 (en) 2013-10-17
SI2258871T1 (sl) 2014-09-30
EP2258871B1 (en) 2014-05-14
HRP20140692T1 (hr) 2014-09-26
IL233548A0 (en) 2014-08-31
IL199894A (en) 2014-11-30
PL2258871T3 (pl) 2014-10-31
WO2008087040A3 (en) 2008-10-16
EP2258871A1 (en) 2010-12-08

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM