ES2312012T3 - Nuevos compuestos de telurio y su uso como inmunomodulares. - Google Patents
Nuevos compuestos de telurio y su uso como inmunomodulares. Download PDFInfo
- Publication number
- ES2312012T3 ES2312012T3 ES05779419T ES05779419T ES2312012T3 ES 2312012 T3 ES2312012 T3 ES 2312012T3 ES 05779419 T ES05779419 T ES 05779419T ES 05779419 T ES05779419 T ES 05779419T ES 2312012 T3 ES2312012 T3 ES 2312012T3
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- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/18—Antioxidants, e.g. antiradicals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C395/00—Compounds containing tellurium
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
- C07F11/005—Compounds containing elements of Groups 6 or 16 of the Periodic Table compounds without a metal-carbon linkage
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61066004P | 2004-09-17 | 2004-09-17 | |
| US610660P | 2004-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2312012T3 true ES2312012T3 (es) | 2009-02-16 |
Family
ID=35985262
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05779419T Expired - Lifetime ES2312012T3 (es) | 2004-09-17 | 2005-09-15 | Nuevos compuestos de telurio y su uso como inmunomodulares. |
| ES05779639.3T Expired - Lifetime ES2614113T3 (es) | 2004-09-17 | 2005-09-15 | Uso de tricloro (dioxietilen-O,O) telurato de amonio (AS101) para la inhibición de la enzima convertidora de interleucina-1 beta |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05779639.3T Expired - Lifetime ES2614113T3 (es) | 2004-09-17 | 2005-09-15 | Uso de tricloro (dioxietilen-O,O) telurato de amonio (AS101) para la inhibición de la enzima convertidora de interleucina-1 beta |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7709524B2 (enExample) |
| EP (3) | EP1791535B1 (enExample) |
| JP (1) | JP2008513439A (enExample) |
| AT (1) | ATE402709T1 (enExample) |
| AU (1) | AU2005283719A1 (enExample) |
| CA (3) | CA2580643C (enExample) |
| DE (1) | DE602005008622D1 (enExample) |
| ES (2) | ES2312012T3 (enExample) |
| PT (1) | PT1796660T (enExample) |
| WO (3) | WO2006030437A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005060341A2 (en) | 2003-12-18 | 2005-07-07 | Biomas, Ltd | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
| DK1715785T3 (da) * | 2004-01-22 | 2014-06-30 | Biomas Ltd | Terapeutiske fremgangsmåder og farmaceutiske sammensætninger tilbehandling af vorter med tellurforbindelser |
| WO2006030440A2 (en) * | 2004-09-17 | 2006-03-23 | Biomas Ltd. | Use of tellurium compounds as adjuvants |
| ES2312012T3 (es) * | 2004-09-17 | 2009-02-16 | Biomas Ltd. | Nuevos compuestos de telurio y su uso como inmunomodulares. |
| WO2006075314A2 (en) | 2005-01-11 | 2006-07-20 | Jemtex Ink Jet Printing Ltd. | Inkjet printer and method of controlling same |
| EP1924254A4 (en) * | 2005-09-15 | 2011-01-19 | Biomas Ltd | USE OF TELLURO COMPOUNDS FOR PROTECTION AGAINST ULTRAVIOLET RADIATION |
| EP1862166A1 (en) * | 2006-06-01 | 2007-12-05 | Yolanda Rodemer | Use of allopurinol for the treatment of palmar plantar erythrodysesthesia |
| PL2035006T3 (pl) * | 2006-06-01 | 2010-07-30 | Nobera Pharma Sl | Zastosowanie allopurynolu do leczenia erytrodyzestezji dłoniowo-podeszwowej |
| US9216197B2 (en) | 2006-09-11 | 2015-12-22 | Biomas Ltd. | Topical formulations of tellurium-containing compounds |
| WO2009066301A2 (en) * | 2007-11-23 | 2009-05-28 | Biomas Ltd. | Methods and compositions for treating pox virus with tellurium-containing compounds |
| LT2826371T (lt) | 2007-11-23 | 2019-06-25 | Feramda Ltd. | Būdai ir kompozicijos, skirti integrinų slopinimui naudojant telūro turinčius junginius |
| US20120035260A1 (en) * | 2009-01-08 | 2012-02-09 | Biomas Ltd. | Tellurium-containing compounds for affecting female's reproductive system following chemotherapy and/or radiotherapy |
| EP2385757A4 (en) * | 2009-01-08 | 2012-12-26 | Biomas Ltd | TELL-CONTAINING COMPOUNDS FOR MANIPULATING MALE FRUITABILITY AFTER CHEMOTHERAPY AND / OR RADIATION THERAPY |
| EP2246057A1 (en) | 2009-04-29 | 2010-11-03 | Nobera Pharma, S.L. | Use of allopurinol for the treatment of hand foot skin reaction |
| WO2010146547A1 (en) * | 2009-06-16 | 2010-12-23 | Biomas Ltd. | Tellurium-containing compounds for facilitating transplantation |
| EP2483406A2 (en) | 2009-09-30 | 2012-08-08 | President and Fellows of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products |
| WO2012065065A1 (en) * | 2010-11-12 | 2012-05-18 | Follica, Inc. | Methods and compositions for modulating hair growth, wound healing and scar revision |
| EP2648676A4 (en) | 2010-12-06 | 2016-05-04 | Follica Inc | METHODS FOR TREATING CALVITIA AND PROMOTING HAIR GROWTH |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| WO2017141243A1 (en) | 2016-02-18 | 2017-08-24 | Enlivex Therapeutics Ltd. | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11512289B2 (en) | 2015-02-18 | 2022-11-29 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| CN107708811B (zh) | 2015-04-21 | 2021-04-30 | 恩立夫克治疗有限责任公司 | 治疗性汇集的血液凋亡细胞制剂与其用途 |
| EP3617190B1 (en) * | 2017-04-28 | 2023-08-16 | Kyoto University | Organic tellurium compound, method for producing same, living radical polymerization initiator, method for producing vinyl polymer, and vinyl polymer |
| JP7221227B2 (ja) | 2017-06-30 | 2023-02-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 発毛を調節するための組成物及び方法 |
| WO2019067860A1 (en) * | 2017-09-29 | 2019-04-04 | The Regents Of The University Of California | COMPOSITIONS AND METHODS FOR MODULATION OF HAIR GROWTH |
| JP2021042161A (ja) * | 2019-09-11 | 2021-03-18 | 国立大学法人東海国立大学機構 | 脱毛剤、脱毛モデル動物及び白髪モデル動物 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3369550A (en) * | 1967-02-17 | 1968-02-20 | Thomas A. Armao | Cryogenic clamps |
| GB1427415A (en) | 1973-09-21 | 1976-03-10 | Armao T A | Cryosurgical instruments |
| US4139619A (en) * | 1976-05-24 | 1979-02-13 | The Upjohn Company | 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth |
| US4962207A (en) * | 1985-09-30 | 1990-10-09 | Bar-Ilan University | Organic derivatives of tellurium and selenium |
| US4761490A (en) * | 1985-03-15 | 1988-08-02 | Bar-Ilan University | Organic derivatives of tellurium and selenium and their use to stimulate cytokine production |
| US5102908A (en) * | 1985-03-15 | 1992-04-07 | Michael Albeck | Method of treating Acquired Immunedeficiency Syndrome (AIDS) using organic tellurium and selenium derivatives |
| US4752614A (en) * | 1985-09-30 | 1988-06-21 | Bar-Ilan University | Pharmaceutical compositions of tellerium and selenium compounds for the induction of in vivo and in vitro production of cytokines |
| US5093135A (en) | 1985-09-30 | 1992-03-03 | Michael Albeck | Compounds for the induction of in vivo and in vitro production of cytokines |
| US4764461A (en) * | 1985-09-30 | 1988-08-16 | Bar-Ilan University | Tellurium and selenium compounds for the induction of in vivo and in vitro production of cytokines |
| US4929739A (en) | 1988-03-24 | 1990-05-29 | Bar-Ilan University | Complexes of tellurium and selenium derivatives |
| DE4007473A1 (de) | 1990-03-09 | 1991-09-12 | Tomsk G Med I | Kryoskalpell |
| US5271925A (en) * | 1990-03-09 | 1993-12-21 | Benjamin Sredni | Method for protecting against the effects of radiation which is based on the administration of a selenium or tellurium based compound |
| US5213899A (en) * | 1990-12-17 | 1993-05-25 | General Electric Company | Room temperature vulcanizable silicone compositions |
| US5262149A (en) * | 1992-08-13 | 1993-11-16 | Benjamin Sredni | Method of treating or preventing alopecia |
| ATE175875T1 (de) | 1994-09-01 | 1999-02-15 | Upjohn Co | Tirilazad parentale formulierung mit einem co- lösungsmittel |
| US5576347A (en) | 1994-11-14 | 1996-11-19 | Sredni; Benjamin | Method of treating gastric ulcers |
| US5654328A (en) * | 1994-12-15 | 1997-08-05 | Sredni; Benjamin | Method and composition for reducing tumor development with a combination of platinum and tellurium or selenium compounds |
| AU699442B2 (en) | 1994-12-15 | 1998-12-03 | Baker Norton Pharmaceuticals, Inc. | Method and composition for reducing tumor development with a combination of a taxane compound and a tellurium and/or selenium compound |
| PT1064298E (pt) * | 1998-03-19 | 2009-01-02 | Vertex Pharma | Inibidores de caspasas |
| US6428534B1 (en) * | 1999-02-24 | 2002-08-06 | Cryovascular Systems, Inc. | Cryogenic angioplasty catheter |
| KR20020005665A (ko) * | 1999-04-09 | 2002-01-17 | 추후보정 | 카스파제 저해제 및 그것의 용도 |
| TR200200767T1 (tr) * | 2000-05-23 | 2002-09-23 | Vertex Pharmaceuticals Incorporated | Kaspaz engelleyiciler ve kullanımları |
| KR20030025235A (ko) * | 2000-06-07 | 2003-03-28 | 버텍스 파마슈티칼스 인코포레이티드 | 카스파제 억제제 및 이의 용도 |
| US6747008B1 (en) | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
| EP1292610A1 (en) | 2000-06-19 | 2003-03-19 | University Of Southern California | Methods for treating and preventing alopecia |
| DE60127860T2 (de) * | 2000-11-21 | 2008-01-17 | Vertex Pharmaceuticals Inc., Cambridge | Imidazol- und benzimidazol- caspase inhibitoren und deren verwendung |
| US20030148970A1 (en) | 2001-01-12 | 2003-08-07 | Besterman Jeffrey M. | Methods for specifically inhibiting histone deacetylase-4 |
| WO2002094263A2 (en) * | 2001-05-23 | 2002-11-28 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| US6472381B1 (en) * | 2001-10-12 | 2002-10-29 | Biomas Inc. | Method of treating psoriasis |
| IL146694A (en) | 2001-11-22 | 2010-12-30 | Biomas Ltd | Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament |
| WO2004002961A1 (en) * | 2002-06-28 | 2004-01-08 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| WO2004058718A1 (en) * | 2002-12-20 | 2004-07-15 | Vertex Pharmaceuticals Incorporated | 4-oxo-3-(1-oxo-1h-isoquinolin-2-ylacetylamino)-pentanoic acid ester and amide derivatives and their use as caspase inhibitors |
| WO2005060341A2 (en) | 2003-12-18 | 2005-07-07 | Biomas, Ltd | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
| CA2580399C (en) * | 2004-09-15 | 2015-07-07 | Itamar Medical Ltd. | Method and apparatus for non-invasively measuring physiological parameters, particularly blood flow and venous capacitance |
| ES2312012T3 (es) | 2004-09-17 | 2009-02-16 | Biomas Ltd. | Nuevos compuestos de telurio y su uso como inmunomodulares. |
| WO2006030440A2 (en) | 2004-09-17 | 2006-03-23 | Biomas Ltd. | Use of tellurium compounds as adjuvants |
-
2005
- 2005-09-15 ES ES05779419T patent/ES2312012T3/es not_active Expired - Lifetime
- 2005-09-15 DE DE602005008622T patent/DE602005008622D1/de not_active Expired - Lifetime
- 2005-09-15 CA CA2580643A patent/CA2580643C/en not_active Expired - Fee Related
- 2005-09-15 CA CA2580642A patent/CA2580642C/en not_active Expired - Fee Related
- 2005-09-15 AU AU2005283719A patent/AU2005283719A1/en not_active Abandoned
- 2005-09-15 EP EP05779419A patent/EP1791535B1/en not_active Expired - Lifetime
- 2005-09-15 JP JP2007531953A patent/JP2008513439A/ja active Pending
- 2005-09-15 EP EP05779639.3A patent/EP1796660B1/en not_active Expired - Lifetime
- 2005-09-15 ES ES05779639.3T patent/ES2614113T3/es not_active Expired - Lifetime
- 2005-09-15 PT PT57796393T patent/PT1796660T/pt unknown
- 2005-09-15 WO PCT/IL2005/000989 patent/WO2006030437A2/en not_active Ceased
- 2005-09-15 WO PCT/IL2005/000991 patent/WO2006030439A2/en not_active Ceased
- 2005-09-15 US US11/663,032 patent/US7709524B2/en not_active Expired - Fee Related
- 2005-09-15 CA CA002580804A patent/CA2580804A1/en not_active Abandoned
- 2005-09-15 US US11/663,031 patent/US7652065B2/en not_active Expired - Fee Related
- 2005-09-15 EP EP05784166A patent/EP1802292A4/en not_active Withdrawn
- 2005-09-15 US US11/662,743 patent/US20090269418A1/en not_active Abandoned
- 2005-09-15 WO PCT/IL2005/000990 patent/WO2006030438A2/en not_active Ceased
- 2005-09-15 AT AT05779419T patent/ATE402709T1/de not_active IP Right Cessation
-
2009
- 2009-12-02 US US12/629,071 patent/US20100081623A1/en not_active Abandoned
-
2010
- 2010-03-22 US US12/728,362 patent/US8623908B2/en not_active Expired - Fee Related
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