ES2292643T3 - Tratamiento de los efectos colaterales de la estatina. - Google Patents
Tratamiento de los efectos colaterales de la estatina. Download PDFInfo
- Publication number
- ES2292643T3 ES2292643T3 ES01998341T ES01998341T ES2292643T3 ES 2292643 T3 ES2292643 T3 ES 2292643T3 ES 01998341 T ES01998341 T ES 01998341T ES 01998341 T ES01998341 T ES 01998341T ES 2292643 T3 ES2292643 T3 ES 2292643T3
- Authority
- ES
- Spain
- Prior art keywords
- uridine
- statin
- salt
- alkyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Landscapes
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| WO2004105742A1 (en) * | 2003-06-02 | 2004-12-09 | Isis Innovation Limited | Treatment of muscle fatigue |
| US20060280721A1 (en) | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
| ES2631152T3 (es) | 2004-01-22 | 2017-08-28 | University Of Miami | Formulaciones de coenzima Q10 tópicas o intravenosas para su uso en el tratamiento del cáncer |
| EP1784172A4 (en) * | 2004-06-21 | 2007-12-19 | Hutchison Medipharma Entpr Ltd | CANCER CHEMOTHERAPY |
| WO2006009840A1 (en) * | 2004-06-21 | 2006-01-26 | Hutchison Medipharma Enterprises Limited | Benzoquinone compounds as a anti-cancer agents |
| JP4896501B2 (ja) * | 2004-11-26 | 2012-03-14 | 第一三共株式会社 | 血中遊離脂肪酸低下作用を有する医薬組成物 |
| WO2006057209A1 (ja) * | 2004-11-26 | 2006-06-01 | Sankyo Company, Limited | 血中遊離脂肪酸低下作用を有する医薬組成物 |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| EP2564843B1 (en) | 2005-06-01 | 2018-12-26 | Bioelectron Technology Corporation | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| CA2642761A1 (en) * | 2006-02-23 | 2007-08-30 | Iomedix Sleep International Srl | Compositions and methods for the induction and maintenance of quality sleep |
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| ES2836184T3 (es) * | 2006-05-02 | 2021-06-24 | Univ Miami | Formulaciones tópicas de co-enzima Q10 y tratamiento de heridas |
| CN106038532B (zh) | 2008-01-04 | 2019-05-14 | 牛津大学科技创新有限公司 | 用作降低血脂药剂的酮体和酮体酯 |
| KR101686917B1 (ko) | 2008-02-29 | 2016-12-15 | 바이오랩 세너스 팔마씨우티카 엘티디에이. | 라세탐 및 카르니틴을 포함하는 약학 조성물 및 그의 제조방법 |
| EP2271325A4 (en) | 2008-04-11 | 2011-11-09 | Cytotech Labs Llc | METHODS AND USE OF INDUCING APOPTOSIS IN CANCER CELLS |
| US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
| MX363223B (es) | 2008-09-10 | 2019-03-15 | Bioelectron Tech Corp | Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox. |
| JP5426918B2 (ja) * | 2009-04-20 | 2014-02-26 | 株式会社 伊藤園 | ウリジンを含有する抗疲労剤又は体力向上剤 |
| US10519504B2 (en) | 2009-05-11 | 2019-12-31 | Berg Llc | Methods for treatment of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
| US8557236B2 (en) * | 2010-02-09 | 2013-10-15 | Vascure Natural LLC | Cardiovascular support supplement and compositions and methods thereof |
| GB201002983D0 (en) | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
| EP2694463B8 (en) | 2011-04-04 | 2019-10-09 | Berg LLC | Treating central nervous system tumors with coenzyme q10 |
| MX2014001823A (es) | 2011-08-15 | 2014-08-21 | Technion Res & Dev Foundation | Combinaciones de corroles y estatinas. |
| TWI489982B (zh) * | 2012-09-18 | 2015-07-01 | Univ China Medical | 苯醌類化合物應用於抑制動脈粥狀血管硬化之用途 |
| TWI504390B (zh) * | 2012-09-18 | 2015-10-21 | Univ China Medical | 苯醌類化合物應用於抑制黑色素瘤細胞之Ｗｎｔ／β－ｃａｔｅｎｉｎ訊息途徑之用途 |
| DK2914251T3 (da) | 2012-11-05 | 2019-11-04 | Us Health | Ketonlegemer til beskyttelse af væv mod beskadigelse som følge af ioniseringsstråling |
| GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
| EP2984066B1 (en) | 2013-03-14 | 2017-02-01 | Oxford University Innovation Limited | Process for producing (r)-3-hydroxybutyl (r)-3-hydroxybutyrate |
| EA032775B1 (ru) | 2013-04-08 | 2019-07-31 | Берг Ллк | Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10 |
| WO2015003246A1 (en) * | 2013-07-09 | 2015-01-15 | Mcmaster University | Combination of a statin with an inflammasome inhibitor |
| WO2015035094A1 (en) | 2013-09-04 | 2015-03-12 | Berg Llc | Methods of treatment of cancer by continuous infusion of coenzyme q10 |
| WO2017087576A1 (en) | 2015-11-16 | 2017-05-26 | Berg Llc | Methods of treatment of temozolomide-resistant glioma using coenzyme q10 |
| WO2017106803A1 (en) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| KR102682716B1 (ko) | 2017-05-17 | 2024-07-08 | 비피지바이오, 인크. | 수포성 표피박리증의 치료 및 예방에서 조효소 q10 제형의 용도 |
| WO2018218287A1 (en) * | 2017-05-29 | 2018-12-06 | Woodlinda Pty Ltd | Treatment and/or prevention of neuropathic symptoms associated with diabetes mellitus type ii |
| WO2019071353A1 (en) * | 2017-10-13 | 2019-04-18 | Exerkine Corporation | USE OF XC-SYSTEM INHIBITOR FOR THE TREATMENT OF STATIN-INDUCED MYALGIA |
| KR102060722B1 (ko) * | 2017-11-06 | 2020-02-11 | 연세대학교 산학협력단 | 스타틴에 의한 약물유해반응용 동물 모델 및 이의 제조방법 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2462312A1 (de) * | 1974-03-04 | 1976-10-14 | Nadrol Chemie Pharma Keizer Kg | Arzneimittel zur behandlung von migraene-erkrankungen |
| SU988814A1 (ru) * | 1979-11-20 | 1983-01-15 | Филиал Всесоюзного научно-исследовательского химико-фармацевтического института им.Серго Орджоникидзе | Соли оротовой кислоты и @ -аминокислот, предупреждающие развитие утомлени при физических нагрузках |
| DE3110560A1 (de) * | 1981-03-18 | 1982-10-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben" |
| US4911917A (en) * | 1988-06-28 | 1990-03-27 | Hauser-Kuhrts, Inc. | Cholesterol-lowering combination comopsitions of magnesium salt and niacin |
| US4929437A (en) * | 1989-02-02 | 1990-05-29 | Merck & Co., Inc. | Coenzyme Q10 with HMG-CoA reductase inhibitors |
| CA2007983C (en) * | 1989-01-18 | 1996-12-10 | Michael S. Brown | Coenzyme q10 with hmg-coa reductase inhibitors |
| US5316765A (en) * | 1989-09-07 | 1994-05-31 | Karl Folkers Foundation For Biomedical And Clinical Research | Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies |
| ES2146228T3 (es) * | 1992-02-24 | 2000-08-01 | Univ East Carolina | Metodo para inhibir la carcinogenesis mediante tratamiento con deshidro-epiandrosterona y sus analogos. |
| BE1005939A6 (fr) * | 1992-05-14 | 1994-03-15 | Pirmez Thierry Dr | Utilisation des sels de l'acide orotique comme tranporteurs preferentiels d'oligo-elements. |
| WO1993024650A1 (en) * | 1992-05-28 | 1993-12-09 | Monash University | Therapeutic compositions |
| AT405477B (de) * | 1996-04-03 | 1999-08-25 | Norbert Mag Fuchs | Kombinationspräparat |
| US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
| US6245800B1 (en) * | 1999-06-08 | 2001-06-12 | Sigma-Tau | Method of preventing or treating statin-induced toxic effects using L-carnitine or an alkanoyl L-carnitine |
| IT1317008B1 (it) * | 2000-04-04 | 2003-05-26 | Sigma Tau Healthscience Spa | Integratore alimentare energizzante sulla muscolatura scheletrica eprotettivo sull'apparato cardiovascolare. |
| US6420342B1 (en) * | 2000-05-08 | 2002-07-16 | N.V. Nutricia | Nutritional preparation comprising ribose and medical use thereof |
-
2000
- 2000-11-29 AU AUPR1773A patent/AUPR177300A0/en not_active Abandoned
-
2001
- 2001-11-29 EP EP01998341A patent/EP1343488B1/en not_active Expired - Lifetime
- 2001-11-29 AU AU2330202A patent/AU2330202A/xx active Pending
- 2001-11-29 JP JP2002545692A patent/JP4596734B2/ja not_active Expired - Fee Related
- 2001-11-29 AU AU2002223302A patent/AU2002223302B2/en not_active Ceased
- 2001-11-29 CA CA2429979A patent/CA2429979C/en not_active Expired - Fee Related
- 2001-11-29 ES ES01998341T patent/ES2292643T3/es not_active Expired - Lifetime
- 2001-11-29 AT AT01998341T patent/ATE369845T1/de not_active IP Right Cessation
- 2001-11-29 NZ NZ526069A patent/NZ526069A/en not_active IP Right Cessation
- 2001-11-29 DE DE60130023T patent/DE60130023T2/de not_active Expired - Lifetime
- 2001-11-29 US US10/433,074 patent/US20040063661A1/en not_active Abandoned
- 2001-11-29 WO PCT/AU2001/001545 patent/WO2002043721A1/en not_active Ceased
-
2010
- 2010-02-16 US US12/706,257 patent/US20100144665A1/en not_active Abandoned
- 2010-07-02 JP JP2010151665A patent/JP2010248230A/ja active Pending
- 2010-08-04 US US12/849,943 patent/US20100323981A1/en not_active Abandoned
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| EP1343488A1 (en) | 2003-09-17 |
| AU2002223302B2 (en) | 2006-08-31 |
| DE60130023T2 (de) | 2008-05-08 |
| JP2010248230A (ja) | 2010-11-04 |
| US20100323981A1 (en) | 2010-12-23 |
| CA2429979A1 (en) | 2002-06-06 |
| AUPR177300A0 (en) | 2000-12-21 |
| NZ526069A (en) | 2006-11-30 |
| JP4596734B2 (ja) | 2010-12-15 |
| CA2429979C (en) | 2011-11-15 |
| AU2330202A (en) | 2002-06-11 |
| DE60130023D1 (de) | 2007-09-27 |
| US20100144665A1 (en) | 2010-06-10 |
| HK1059044A1 (en) | 2004-06-18 |
| JP2004531468A (ja) | 2004-10-14 |
| EP1343488B1 (en) | 2007-08-15 |
| ATE369845T1 (de) | 2007-09-15 |
| US20040063661A1 (en) | 2004-04-01 |
| EP1343488A4 (en) | 2005-05-04 |
| WO2002043721A1 (en) | 2002-06-06 |
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