ES2287161T3 - Analogos de trombomodulina para uso en la recuperacion de la lesion de la medula espinal. - Google Patents

Analogos de trombomodulina para uso en la recuperacion de la lesion de la medula espinal. Download PDF

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Publication number
ES2287161T3
ES2287161T3 ES01973674T ES01973674T ES2287161T3 ES 2287161 T3 ES2287161 T3 ES 2287161T3 ES 01973674 T ES01973674 T ES 01973674T ES 01973674 T ES01973674 T ES 01973674T ES 2287161 T3 ES2287161 T3 ES 2287161T3
Authority
ES
Spain
Prior art keywords
thrombomodulin
injury
amino acid
baselineskip
native
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01973674T
Other languages
English (en)
Spanish (es)
Inventor
Barry W. Festoff
Michael John Morser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Paion Deutschland GmbH
Original Assignee
Paion Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paion Deutschland GmbH filed Critical Paion Deutschland GmbH
Application granted granted Critical
Publication of ES2287161T3 publication Critical patent/ES2287161T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/366—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
  • Communication Cables (AREA)
  • Signal Processing Not Specific To The Method Of Recording And Reproducing (AREA)
  • Ropes Or Cables (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES01973674T 2000-08-31 2001-08-31 Analogos de trombomodulina para uso en la recuperacion de la lesion de la medula espinal. Expired - Lifetime ES2287161T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22971400P 2000-08-31 2000-08-31
US229714P 2000-08-31
US09/938,405 US20020111296A1 (en) 2000-08-31 2001-08-23 Thrombomodulin analogs for use in recovery of spinal cord injury
US938405 2001-08-23

Publications (1)

Publication Number Publication Date
ES2287161T3 true ES2287161T3 (es) 2007-12-16

Family

ID=26923554

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01973674T Expired - Lifetime ES2287161T3 (es) 2000-08-31 2001-08-31 Analogos de trombomodulina para uso en la recuperacion de la lesion de la medula espinal.

Country Status (13)

Country Link
US (3) US20020111296A1 (https=)
EP (1) EP1365788B1 (https=)
JP (1) JP2004521076A (https=)
AT (1) ATE361755T1 (https=)
AU (2) AU2001293229B2 (https=)
CA (1) CA2420900A1 (https=)
DE (1) DE60128399T2 (https=)
DK (1) DK1365788T3 (https=)
ES (1) ES2287161T3 (https=)
IL (2) IL154600A0 (https=)
NO (1) NO20030919L (https=)
PT (1) PT1365788E (https=)
WO (1) WO2002017953A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006005362A1 (en) * 2004-07-13 2006-01-19 Paion Deutschland Gmbh Production of mammalian proteins in plant cells
US20060148695A1 (en) * 2005-01-03 2006-07-06 National Cheng Kung University Novel angiogenic composition and use thereof
US8293710B2 (en) * 2005-01-03 2012-10-23 Blue Blood Biotech Corp. Method for treating wounds using an EGF-like domain of thrombomodulin
JP2009504636A (ja) * 2005-08-11 2009-02-05 メディジーンズ カンパニー リミテッド 血漿または血清を含む神経損傷治療用の医薬組成物
EP2014296A1 (en) * 2007-07-10 2009-01-14 PAION Deutschland GmbH Novel strategies for increasing the reperfusion in obstructed blood vessel
AR067345A1 (es) * 2007-07-10 2009-10-07 Paion Deutschland Gmbh Uso de trombomodulina para la preparacion de un medicamento trombolitico
EP2320936A1 (en) * 2008-07-16 2011-05-18 PAION Deutschland GmbH Prevention and treatment of radiation injury
WO2010006635A1 (en) * 2008-07-16 2010-01-21 Paion Deutschland Gmbh Treatment of inflammatory bowel disease
PL2857037T3 (pl) 2012-05-31 2019-12-31 Kinki University Środek do leczenia profilaktycznego i/lub terapeutycznego obwodowego bólu neuropatycznego wywoływanego przez środek przeciwnowotworowy
WO2020067389A1 (ja) * 2018-09-28 2020-04-02 旭化成ファーマ株式会社 抗悪性腫瘍剤による末梢神経障害の症状軽減及び／又は発症抑制のための医薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256770A (en) * 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
US5466668A (en) * 1989-04-28 1995-11-14 Schering Aktiengesellschaft Superior thrombomodulin analogs for pharmaceutical use
US6063763A (en) * 1989-04-28 2000-05-16 Schering Aktiengesellschaft Protease-resistant thrombomodulin analogs
JP3789147B2 (ja) * 1995-04-11 2006-06-21 旭化成ファーマ株式会社 脊髄損傷後の神経障害に対する治療剤

Also Published As

Publication number Publication date
US20040002446A1 (en) 2004-01-01
IL154600A (en) 2009-02-11
EP1365788B1 (en) 2007-05-09
DE60128399D1 (de) 2007-06-21
JP2004521076A (ja) 2004-07-15
US20020111296A1 (en) 2002-08-15
WO2002017953A3 (en) 2003-10-09
PT1365788E (pt) 2007-08-10
NO20030919L (no) 2003-04-10
IL154600A0 (en) 2003-09-17
US20090143281A1 (en) 2009-06-04
HK1062398A1 (en) 2004-11-05
ATE361755T1 (de) 2007-06-15
WO2002017953A2 (en) 2002-03-07
DK1365788T3 (da) 2007-09-17
AU9322901A (en) 2002-03-13
NO20030919D0 (no) 2003-02-27
DE60128399T2 (de) 2008-01-10
AU2001293229B2 (en) 2007-04-05
CA2420900A1 (en) 2002-03-07
EP1365788A2 (en) 2003-12-03

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