ES2287028T3 - Composiciones y metodos para la prevencion o el tratamiento de cancer y de la perdida osea asociada con el cancer. - Google Patents
Composiciones y metodos para la prevencion o el tratamiento de cancer y de la perdida osea asociada con el cancer. Download PDFInfo
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- ES2287028T3 ES2287028T3 ES00955737T ES00955737T ES2287028T3 ES 2287028 T3 ES2287028 T3 ES 2287028T3 ES 00955737 T ES00955737 T ES 00955737T ES 00955737 T ES00955737 T ES 00955737T ES 2287028 T3 ES2287028 T3 ES 2287028T3
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38954599A | 1999-09-03 | 1999-09-03 | |
| US389545 | 1999-09-03 |
Publications (1)
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|---|---|
| ES2287028T3 true ES2287028T3 (es) | 2007-12-16 |
Family
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Family Applications (1)
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| ES00955737T Expired - Lifetime ES2287028T3 (es) | 1999-09-03 | 2000-08-18 | Composiciones y metodos para la prevencion o el tratamiento de cancer y de la perdida osea asociada con el cancer. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060019887A1 (https=) |
| EP (2) | EP1140136B1 (https=) |
| JP (2) | JP2003508491A (https=) |
| KR (1) | KR20010085996A (https=) |
| CN (1) | CN1345246A (https=) |
| AT (1) | ATE362374T1 (https=) |
| AU (1) | AU6788900A (https=) |
| CA (1) | CA2349406C (https=) |
| DE (1) | DE60034871T2 (https=) |
| ES (1) | ES2287028T3 (https=) |
| HU (1) | HUP0104688A3 (https=) |
| IL (1) | IL142900A0 (https=) |
| WO (1) | WO2001017543A2 (https=) |
| ZA (1) | ZA200103565B (https=) |
Families Citing this family (26)
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| IL117175A (en) | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| DE69740107D1 (de) | 1996-12-23 | 2011-03-10 | Immunex Corp | Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie |
| ES2263204T5 (es) | 1997-04-15 | 2013-10-14 | Daiichi Sankyo Company, Limited | Nueva proteína y proceso para producir la misma |
| ES2284203T5 (es) | 1997-04-16 | 2016-03-11 | Amgen Inc. | Proteínas de unión a osteoprotegerina y sus receptores |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| AU762574B2 (en) | 1998-05-14 | 2003-06-26 | Immunex Corporation | Method of inhibiting osteoclast activity |
| HUP0104126A3 (en) * | 1998-10-28 | 2004-07-28 | Sankyo Company Ltd Chuo Ku | Remedies for bone metabolic errors |
| US20020090646A1 (en) * | 2000-05-03 | 2002-07-11 | Amgen Inc. | Calcitonin-related molecules |
| WO2002024896A2 (en) | 2000-09-22 | 2002-03-28 | Immunex Corporation | Screening assays for agonists or antagonists of receptor activat or of nf-kb |
| MXPA03011270A (es) * | 2001-06-06 | 2004-03-18 | Immunex Corp | Uso de antagonistas rank para tratar cancer. |
| EP1270015A3 (en) * | 2001-06-29 | 2004-02-25 | Sankyo Company Limited | A complex comprising OCIF and Polysaccharide |
| US7718776B2 (en) | 2002-04-05 | 2010-05-18 | Amgen Inc. | Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors |
| US7585840B2 (en) | 2002-04-10 | 2009-09-08 | Merck Serono S.A. | Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease |
| EP1515743A2 (en) | 2002-04-10 | 2005-03-23 | Applied Research Systems ARS Holding N.V. | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
| CA2487428A1 (en) * | 2002-06-07 | 2003-12-18 | Trillium Therapeutics Inc. | Cd200-receptor mediated modulation of bone development |
| BRPI0519008A2 (pt) * | 2004-12-13 | 2008-12-23 | Evogenix Ltd | proteÍnas variantes de osteoprotegerina |
| TW200714289A (en) * | 2005-02-28 | 2007-04-16 | Genentech Inc | Treatment of bone disorders |
| ES2699077T3 (es) * | 2009-06-12 | 2019-02-07 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| CN102242209B (zh) * | 2011-07-05 | 2013-12-11 | 北京大学人民医院 | 基于多个基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒 |
| AU2012375257B2 (en) * | 2012-03-31 | 2019-09-12 | R-Pharm International, Limited Liability Company | Osteoprotegerin derived composition and use thereof |
| KR20160127824A (ko) * | 2014-03-06 | 2016-11-04 | 알-팜 오버씨즈, 인코포레이티드 | 오스테오프로테게린 유래의 rankl 억제제 |
| KR101576904B1 (ko) * | 2014-07-31 | 2015-12-14 | (주)케어젠 | 파골세포 분화 및 활성 억제능을 갖는 펩타이드 및 이의 용도 |
| EP3535585A1 (en) * | 2016-11-04 | 2019-09-11 | Aarhus Universitet | Identification and treatment of tumors characterized by an overexpression of the neonatal fc receptor |
| CN110483647B (zh) * | 2019-08-19 | 2021-02-09 | 重庆大学附属肿瘤医院 | 一种抗肿瘤多肽及其应用 |
| JP2023525960A (ja) * | 2020-04-15 | 2023-06-20 | セラダプティブ インク | 骨に標的治療薬を送達するための組成物および方法 |
| KR20230118573A (ko) * | 2020-11-11 | 2023-08-11 | 에이치큐 한 | 액티빈/tgf-베타 및 rankl의 이작용성 길항제 및 이의 용도 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4710473A (en) * | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
| AU610083B2 (en) * | 1986-08-18 | 1991-05-16 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents |
| FR2640537B1 (fr) * | 1988-12-21 | 1992-02-21 | Levy Guy | Installation et procede utilisant l'effet laser, pour la coupe ou la vaporisation de materiaux et tissus divers |
| US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| JP3507486B2 (ja) * | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| ATE311895T1 (de) * | 1992-05-26 | 2005-12-15 | Immunex Corp | Neue zytokine die cd30 binden |
| US5457035A (en) * | 1993-07-23 | 1995-10-10 | Immunex Corporation | Cytokine which is a ligand for OX40 |
| US5843901A (en) * | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| US20050147611A1 (en) * | 1995-12-22 | 2005-07-07 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
| US20030207827A1 (en) * | 1995-12-22 | 2003-11-06 | William J. Boyle | Osteoprotegerin |
| US6369027B1 (en) * | 1995-12-22 | 2002-04-09 | Amgen Inc. | Osteoprotegerin |
| US6613544B1 (en) * | 1995-12-22 | 2003-09-02 | Amgen Inc. | Osteoprotegerin |
| US7005413B1 (en) * | 1995-12-22 | 2006-02-28 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
-
2000
- 2000-08-18 IL IL14290000A patent/IL142900A0/xx unknown
- 2000-08-18 JP JP2001521333A patent/JP2003508491A/ja not_active Withdrawn
- 2000-08-18 ES ES00955737T patent/ES2287028T3/es not_active Expired - Lifetime
- 2000-08-18 AT AT00955737T patent/ATE362374T1/de not_active IP Right Cessation
- 2000-08-18 KR KR1020017005606A patent/KR20010085996A/ko not_active Ceased
- 2000-08-18 AU AU67889/00A patent/AU6788900A/en not_active Abandoned
- 2000-08-18 HU HU0104688A patent/HUP0104688A3/hu unknown
- 2000-08-18 EP EP00955737A patent/EP1140136B1/en not_active Expired - Lifetime
- 2000-08-18 CN CN00802472A patent/CN1345246A/zh active Pending
- 2000-08-18 WO PCT/US2000/022806 patent/WO2001017543A2/en not_active Ceased
- 2000-08-18 CA CA2349406A patent/CA2349406C/en not_active Expired - Fee Related
- 2000-08-18 DE DE60034871T patent/DE60034871T2/de not_active Expired - Lifetime
- 2000-08-18 EP EP06022155A patent/EP1800691A3/en not_active Withdrawn
-
2001
- 2001-05-03 ZA ZA200103565A patent/ZA200103565B/en unknown
-
2004
- 2004-09-22 US US10/948,053 patent/US20060019887A1/en not_active Abandoned
-
2011
- 2011-06-01 JP JP2011123144A patent/JP2011225581A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL142900A0 (en) | 2002-04-21 |
| ZA200103565B (en) | 2002-05-03 |
| ATE362374T1 (de) | 2007-06-15 |
| EP1140136A2 (en) | 2001-10-10 |
| CA2349406A1 (en) | 2001-03-15 |
| HUP0104688A3 (en) | 2004-07-28 |
| HUP0104688A2 (hu) | 2002-03-28 |
| DE60034871D1 (de) | 2007-06-28 |
| AU6788900A (en) | 2001-04-10 |
| KR20010085996A (ko) | 2001-09-07 |
| CA2349406C (en) | 2011-01-11 |
| DE60034871T2 (de) | 2008-01-17 |
| WO2001017543A3 (en) | 2001-07-26 |
| WO2001017543A2 (en) | 2001-03-15 |
| JP2011225581A (ja) | 2011-11-10 |
| EP1140136B1 (en) | 2007-05-16 |
| US20060019887A1 (en) | 2006-01-26 |
| EP1800691A3 (en) | 2007-10-31 |
| EP1800691A2 (en) | 2007-06-27 |
| CN1345246A (zh) | 2002-04-17 |
| JP2003508491A (ja) | 2003-03-04 |
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