JP2003508491A - 癌および癌に関連する骨損失の予防または治療のための組成物および方法 - Google Patents
癌および癌に関連する骨損失の予防または治療のための組成物および方法Info
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- JP2003508491A JP2003508491A JP2001521333A JP2001521333A JP2003508491A JP 2003508491 A JP2003508491 A JP 2003508491A JP 2001521333 A JP2001521333 A JP 2001521333A JP 2001521333 A JP2001521333 A JP 2001521333A JP 2003508491 A JP2003508491 A JP 2003508491A
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38954599A | 1999-09-03 | 1999-09-03 | |
| US09/389,545 | 1999-09-03 | ||
| PCT/US2000/022806 WO2001017543A2 (en) | 1999-09-03 | 2000-08-18 | Compositions and methods for the prevention or treatment of cancer and bone loss associated with cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011123144A Division JP2011225581A (ja) | 1999-09-03 | 2011-06-01 | 癌および癌に関連する骨損失の予防または治療のための組成物および方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2003508491A true JP2003508491A (ja) | 2003-03-04 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001521333A Withdrawn JP2003508491A (ja) | 1999-09-03 | 2000-08-18 | 癌および癌に関連する骨損失の予防または治療のための組成物および方法 |
| JP2011123144A Pending JP2011225581A (ja) | 1999-09-03 | 2011-06-01 | 癌および癌に関連する骨損失の予防または治療のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011123144A Pending JP2011225581A (ja) | 1999-09-03 | 2011-06-01 | 癌および癌に関連する骨損失の予防または治療のための組成物および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060019887A1 (https=) |
| EP (2) | EP1140136B1 (https=) |
| JP (2) | JP2003508491A (https=) |
| KR (1) | KR20010085996A (https=) |
| CN (1) | CN1345246A (https=) |
| AT (1) | ATE362374T1 (https=) |
| AU (1) | AU6788900A (https=) |
| CA (1) | CA2349406C (https=) |
| DE (1) | DE60034871T2 (https=) |
| ES (1) | ES2287028T3 (https=) |
| HU (1) | HUP0104688A3 (https=) |
| IL (1) | IL142900A0 (https=) |
| WO (1) | WO2001017543A2 (https=) |
| ZA (1) | ZA200103565B (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2008522593A (ja) * | 2004-12-13 | 2008-07-03 | エヴォジェニックス・リミテッド | オステオプロテゲリン・バリアントタンパク質 |
| JP2017508792A (ja) * | 2014-03-06 | 2017-03-30 | アール−ファーム・オーバーシーズ・インコーポレイテッドＲ−Ｐｈａｒｍ Ｏｖｅｒｓｅａｓ， Ｉｎｃ． | オステオプロテゲリンはランケル・インヒビターを引き出した |
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| ES2263204T5 (es) | 1997-04-15 | 2013-10-14 | Daiichi Sankyo Company, Limited | Nueva proteína y proceso para producir la misma |
| ES2284203T5 (es) | 1997-04-16 | 2016-03-11 | Amgen Inc. | Proteínas de unión a osteoprotegerina y sus receptores |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| AU762574B2 (en) | 1998-05-14 | 2003-06-26 | Immunex Corporation | Method of inhibiting osteoclast activity |
| HUP0104126A3 (en) * | 1998-10-28 | 2004-07-28 | Sankyo Company Ltd Chuo Ku | Remedies for bone metabolic errors |
| US20020090646A1 (en) * | 2000-05-03 | 2002-07-11 | Amgen Inc. | Calcitonin-related molecules |
| WO2002024896A2 (en) | 2000-09-22 | 2002-03-28 | Immunex Corporation | Screening assays for agonists or antagonists of receptor activat or of nf-kb |
| MXPA03011270A (es) * | 2001-06-06 | 2004-03-18 | Immunex Corp | Uso de antagonistas rank para tratar cancer. |
| EP1270015A3 (en) * | 2001-06-29 | 2004-02-25 | Sankyo Company Limited | A complex comprising OCIF and Polysaccharide |
| US7718776B2 (en) | 2002-04-05 | 2010-05-18 | Amgen Inc. | Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors |
| US7585840B2 (en) | 2002-04-10 | 2009-09-08 | Merck Serono S.A. | Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease |
| EP1515743A2 (en) | 2002-04-10 | 2005-03-23 | Applied Research Systems ARS Holding N.V. | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
| CA2487428A1 (en) * | 2002-06-07 | 2003-12-18 | Trillium Therapeutics Inc. | Cd200-receptor mediated modulation of bone development |
| TW200714289A (en) * | 2005-02-28 | 2007-04-16 | Genentech Inc | Treatment of bone disorders |
| ES2699077T3 (es) * | 2009-06-12 | 2019-02-07 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| CN102242209B (zh) * | 2011-07-05 | 2013-12-11 | 北京大学人民医院 | 基于多个基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒 |
| AU2012375257B2 (en) * | 2012-03-31 | 2019-09-12 | R-Pharm International, Limited Liability Company | Osteoprotegerin derived composition and use thereof |
| KR101576904B1 (ko) * | 2014-07-31 | 2015-12-14 | (주)케어젠 | 파골세포 분화 및 활성 억제능을 갖는 펩타이드 및 이의 용도 |
| EP3535585A1 (en) * | 2016-11-04 | 2019-09-11 | Aarhus Universitet | Identification and treatment of tumors characterized by an overexpression of the neonatal fc receptor |
| CN110483647B (zh) * | 2019-08-19 | 2021-02-09 | 重庆大学附属肿瘤医院 | 一种抗肿瘤多肽及其应用 |
| JP2023525960A (ja) * | 2020-04-15 | 2023-06-20 | セラダプティブ インク | 骨に標的治療薬を送達するための組成物および方法 |
| KR20230118573A (ko) * | 2020-11-11 | 2023-08-11 | 에이치큐 한 | 액티빈/tgf-베타 및 rankl의 이작용성 길항제 및 이의 용도 |
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2000
- 2000-08-18 IL IL14290000A patent/IL142900A0/xx unknown
- 2000-08-18 JP JP2001521333A patent/JP2003508491A/ja not_active Withdrawn
- 2000-08-18 ES ES00955737T patent/ES2287028T3/es not_active Expired - Lifetime
- 2000-08-18 AT AT00955737T patent/ATE362374T1/de not_active IP Right Cessation
- 2000-08-18 KR KR1020017005606A patent/KR20010085996A/ko not_active Ceased
- 2000-08-18 AU AU67889/00A patent/AU6788900A/en not_active Abandoned
- 2000-08-18 HU HU0104688A patent/HUP0104688A3/hu unknown
- 2000-08-18 EP EP00955737A patent/EP1140136B1/en not_active Expired - Lifetime
- 2000-08-18 CN CN00802472A patent/CN1345246A/zh active Pending
- 2000-08-18 WO PCT/US2000/022806 patent/WO2001017543A2/en not_active Ceased
- 2000-08-18 CA CA2349406A patent/CA2349406C/en not_active Expired - Fee Related
- 2000-08-18 DE DE60034871T patent/DE60034871T2/de not_active Expired - Lifetime
- 2000-08-18 EP EP06022155A patent/EP1800691A3/en not_active Withdrawn
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2001
- 2001-05-03 ZA ZA200103565A patent/ZA200103565B/en unknown
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- 2004-09-22 US US10/948,053 patent/US20060019887A1/en not_active Abandoned
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- 2011-06-01 JP JP2011123144A patent/JP2011225581A/ja active Pending
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| JPH11507374A (ja) * | 1995-06-07 | 1999-06-29 | インディアナ ユニバーシティ ファウンデーション | Ｌｈｒｈ拮抗物質ペプチド |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008522593A (ja) * | 2004-12-13 | 2008-07-03 | エヴォジェニックス・リミテッド | オステオプロテゲリン・バリアントタンパク質 |
| JP4870683B2 (ja) * | 2004-12-13 | 2012-02-08 | セファロン・オーストラリア・（ヴィーアイシー）・ピーティーワイ・リミテッド | オステオプロテゲリン・バリアントタンパク質 |
| JP2017508792A (ja) * | 2014-03-06 | 2017-03-30 | アール−ファーム・オーバーシーズ・インコーポレイテッドＲ−Ｐｈａｒｍ Ｏｖｅｒｓｅａｓ， Ｉｎｃ． | オステオプロテゲリンはランケル・インヒビターを引き出した |
Also Published As
| Publication number | Publication date |
|---|---|
| IL142900A0 (en) | 2002-04-21 |
| ZA200103565B (en) | 2002-05-03 |
| ATE362374T1 (de) | 2007-06-15 |
| EP1140136A2 (en) | 2001-10-10 |
| CA2349406A1 (en) | 2001-03-15 |
| HUP0104688A3 (en) | 2004-07-28 |
| HUP0104688A2 (hu) | 2002-03-28 |
| DE60034871D1 (de) | 2007-06-28 |
| AU6788900A (en) | 2001-04-10 |
| KR20010085996A (ko) | 2001-09-07 |
| CA2349406C (en) | 2011-01-11 |
| DE60034871T2 (de) | 2008-01-17 |
| ES2287028T3 (es) | 2007-12-16 |
| WO2001017543A3 (en) | 2001-07-26 |
| WO2001017543A2 (en) | 2001-03-15 |
| JP2011225581A (ja) | 2011-11-10 |
| EP1140136B1 (en) | 2007-05-16 |
| US20060019887A1 (en) | 2006-01-26 |
| EP1800691A3 (en) | 2007-10-31 |
| EP1800691A2 (en) | 2007-06-27 |
| CN1345246A (zh) | 2002-04-17 |
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