ES2275505T3 - Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores. - Google Patents

Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores. Download PDF

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Publication number
ES2275505T3
ES2275505T3 ES00921765T ES00921765T ES2275505T3 ES 2275505 T3 ES2275505 T3 ES 2275505T3 ES 00921765 T ES00921765 T ES 00921765T ES 00921765 T ES00921765 T ES 00921765T ES 2275505 T3 ES2275505 T3 ES 2275505T3
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ES
Spain
Prior art keywords
inhibitor
ras
cancer
receptor
additional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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ES00921765T
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English (en)
Spanish (es)
Inventor
Walter R. Bishop
Diana L. Brassard
Tattanahalli L. Nagabhushan
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Merck Sharp and Dohme LLC
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Schering Corp
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Publication of ES2275505T3 publication Critical patent/ES2275505T3/es
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES00921765T 1999-04-09 2000-04-06 Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores. Expired - Lifetime ES2275505T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/289,255 US6316462B1 (en) 1999-04-09 1999-04-09 Methods of inducing cancer cell death and tumor regression
US289255 1999-04-09

Publications (1)

Publication Number Publication Date
ES2275505T3 true ES2275505T3 (es) 2007-06-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES00921765T Expired - Lifetime ES2275505T3 (es) 1999-04-09 2000-04-06 Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores.

Country Status (24)

Country Link
US (1) US6316462B1 (OSRAM)
EP (1) EP1165078B1 (OSRAM)
JP (1) JP2003529540A (OSRAM)
CN (1) CN100421661C (OSRAM)
AR (1) AR023400A1 (OSRAM)
AT (1) ATE347360T1 (OSRAM)
AU (1) AU783177B2 (OSRAM)
BR (1) BR0009670A (OSRAM)
CA (1) CA2364675A1 (OSRAM)
CY (1) CY1107545T1 (OSRAM)
DE (1) DE60032226T2 (OSRAM)
DK (1) DK1165078T3 (OSRAM)
ES (1) ES2275505T3 (OSRAM)
HK (1) HK1038512B (OSRAM)
HU (1) HUP0200773A3 (OSRAM)
MX (1) MXPA01010211A (OSRAM)
MY (1) MY120841A (OSRAM)
NO (1) NO329133B1 (OSRAM)
NZ (1) NZ514628A (OSRAM)
PE (1) PE20010025A1 (OSRAM)
PT (1) PT1165078E (OSRAM)
TW (1) TWI255184B (OSRAM)
WO (1) WO2000061145A1 (OSRAM)
ZA (1) ZA200108258B (OSRAM)

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EP1165078A1 (en) 2002-01-02
MY120841A (en) 2005-11-30
NZ514628A (en) 2004-01-30
ATE347360T1 (de) 2006-12-15
HUP0200773A2 (hu) 2002-07-29
HUP0200773A3 (en) 2003-04-28
NO20014897D0 (no) 2001-10-08
HK1038512B (en) 2007-04-27
JP2003529540A (ja) 2003-10-07
CN1364084A (zh) 2002-08-14
CA2364675A1 (en) 2000-10-19
DE60032226T2 (de) 2007-10-11
AR023400A1 (es) 2002-09-04
CN100421661C (zh) 2008-10-01
CY1107545T1 (el) 2013-03-13
PT1165078E (pt) 2007-02-28
DK1165078T3 (da) 2007-04-16
US6316462B1 (en) 2001-11-13
WO2000061145A1 (en) 2000-10-19
PE20010025A1 (es) 2001-02-05
DE60032226D1 (de) 2007-01-18
EP1165078B1 (en) 2006-12-06
BR0009670A (pt) 2002-01-15
MXPA01010211A (es) 2002-09-18
AU783177B2 (en) 2005-09-29
ZA200108258B (en) 2003-03-26
NO20014897L (no) 2001-12-10
TWI255184B (en) 2006-05-21
NO329133B1 (no) 2010-08-30
HK1038512A1 (en) 2002-03-22
AU4204100A (en) 2000-11-14

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