ES2264198T3 - Composiciones y metodos para tratar infecciones utilizando peptidos cationicos a solas o en combinacion con antibioticos. - Google Patents
Composiciones y metodos para tratar infecciones utilizando peptidos cationicos a solas o en combinacion con antibioticos.Info
- Publication number
- ES2264198T3 ES2264198T3 ES98907779T ES98907779T ES2264198T3 ES 2264198 T3 ES2264198 T3 ES 2264198T3 ES 98907779 T ES98907779 T ES 98907779T ES 98907779 T ES98907779 T ES 98907779T ES 2264198 T3 ES2264198 T3 ES 2264198T3
- Authority
- ES
- Spain
- Prior art keywords
- baselineskip
- arg
- peptide
- gly
- lys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
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- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4064997P | 1997-03-10 | 1997-03-10 | |
| US40649P | 1997-03-10 | ||
| US08/915,314 US6180604B1 (en) | 1996-08-21 | 1997-08-20 | Compositions and methods for treating infections using analogues of indolicidin |
| US915314 | 1997-08-20 | ||
| US6009997P | 1997-09-26 | 1997-09-26 | |
| US60099P | 1997-09-26 | ||
| US30619 | 1998-02-25 | ||
| US09/030,619 US6503881B2 (en) | 1996-08-21 | 1998-02-25 | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2264198T3 true ES2264198T3 (es) | 2006-12-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98907779T Expired - Lifetime ES2264198T3 (es) | 1997-03-10 | 1998-03-10 | Composiciones y metodos para tratar infecciones utilizando peptidos cationicos a solas o en combinacion con antibioticos. |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6503881B2 (enExample) |
| EP (1) | EP0966481B1 (enExample) |
| JP (1) | JP2002544759A (enExample) |
| AT (1) | ATE333464T1 (enExample) |
| AU (1) | AU6604798A (enExample) |
| CA (1) | CA2282807A1 (enExample) |
| DE (1) | DE69835279T2 (enExample) |
| ES (1) | ES2264198T3 (enExample) |
| WO (1) | WO1998040401A2 (enExample) |
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| US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| IN186245B (enExample) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
| US6172185B1 (en) * | 1998-05-20 | 2001-01-09 | University Of British Columbia | Antimicrobial cationic peptide derivatives of bactenecin |
| GB9818938D0 (en) | 1998-08-28 | 1998-10-21 | Alpharma As | Bioactive peptides |
| US8283315B2 (en) | 1998-08-28 | 2012-10-09 | Lytix Biopharma As | Inhibition of tumour growth |
| US6288212B1 (en) * | 1998-08-28 | 2001-09-11 | The University Of British Columbia | Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor |
| WO2000026344A1 (en) * | 1998-10-30 | 2000-05-11 | Interlink Biotechnologies Llc | Peptides with enhanced stability to protease degradation |
| US6946261B1 (en) | 1998-11-20 | 2005-09-20 | Migenix Inc. | Efficient methods for producing anti-microbial cationic peptides in host cells |
| CN1670217A (zh) * | 1999-02-03 | 2005-09-21 | 特瓦药厂有限公司 | 经微生物学方法制备假单胞菌酸a抗生素的方法 |
| US6399570B1 (en) * | 1999-02-05 | 2002-06-04 | Agennix, Inc. | Antimicrobial/endotoxin neutralizing polypeptide |
| US20030008369A1 (en) * | 1999-03-03 | 2003-01-09 | Board Of Regents, The University Of Texas System | Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases |
| EP1163352A1 (en) * | 1999-03-17 | 2001-12-19 | University Of Victoria Innovation And Development Corporation | Transgenic plants that are resistant to a broad spectrum of pathogens |
| US6835868B1 (en) | 1999-03-17 | 2004-12-28 | University Of Victoria Innovation And Development Corporation | Transgenic plants expressing dermaseptin peptides providing broad spectrum resistance to pathogens |
| EP1180013B1 (en) * | 1999-05-27 | 2006-03-08 | Biocompatibles UK Limited | Local drug delivery |
| US7015309B1 (en) | 1999-06-23 | 2006-03-21 | The Wistar Institute Of Anatomy And Biology | Pyrrhocoricin-derived peptides, and methods of use thereof |
| ES2231275T3 (es) | 1999-10-08 | 2005-05-16 | Affinium Pharmaceuticals, Inc. | Inhibidores de fab i. |
| AU782915B2 (en) * | 1999-12-20 | 2005-09-08 | Sa Majeste La Reine Du Chef Du Canada - Agriculture Et Agroalimentaire Canada | Method and composition for treatment and/or prevention of antibiotic-resistant microorganism infections |
| WO2001053509A2 (en) * | 2000-01-21 | 2001-07-26 | The Wistar Institute Of Anatomy And Biology | Biocidal molecules, macromolecular targets and methods of production and use |
| US8003595B2 (en) | 2000-03-01 | 2011-08-23 | Cellectis | Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei |
| US6632616B2 (en) * | 2000-03-16 | 2003-10-14 | Duke University | Compounds that selectively bind to expanded polyglutamine repeat domains and methods of use thereof |
| US6777592B2 (en) * | 2000-04-14 | 2004-08-17 | E.I. Du Pont Denemours And Company | Arthropod defensins of Scolopendra canidens, Vaejovis carolinianus, and Argiope spp. |
| DE10030781A1 (de) * | 2000-06-29 | 2002-01-17 | Hassan Jomaa | Kombinationspräparate von 3-N-Formylhydroxylaminopropylphosphonsäurederivaten oder 3-N-Acetylhydroxylaminopropylphosphonsäurederivaten mit spezielen pharmazeutischen Wirkstoffen |
| DE10042853A1 (de) * | 2000-08-30 | 2002-04-25 | Florian Lang | Nachweis und Beeinflußung der Expression oder Funktion von CD95/CD95L bei Infektionen |
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| EP0966481A2 (en) | 1999-12-29 |
| US20110150780A1 (en) | 2011-06-23 |
| US6503881B2 (en) | 2003-01-07 |
| AU6604798A (en) | 1998-09-29 |
| DE69835279T2 (de) | 2007-07-12 |
| WO1998040401A2 (en) | 1998-09-17 |
| US20020035061A1 (en) | 2002-03-21 |
| ATE333464T1 (de) | 2006-08-15 |
| HK1025103A1 (en) | 2000-11-03 |
| EP0966481B1 (en) | 2006-07-19 |
| CA2282807A1 (en) | 1998-09-17 |
| JP2002544759A (ja) | 2002-12-24 |
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