ES2235941T3 - Granulos de quetiapina. - Google Patents

Granulos de quetiapina.

Info

Publication number
ES2235941T3
ES2235941T3 ES00960855T ES00960855T ES2235941T3 ES 2235941 T3 ES2235941 T3 ES 2235941T3 ES 00960855 T ES00960855 T ES 00960855T ES 00960855 T ES00960855 T ES 00960855T ES 2235941 T3 ES2235941 T3 ES 2235941T3
Authority
ES
Spain
Prior art keywords
formulation
granules
soluble
binder
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00960855T
Other languages
English (en)
Spanish (es)
Inventor
Daniel Boyd Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10861288&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2235941(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2235941T3 publication Critical patent/ES2235941T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
ES00960855T 1999-09-21 2000-09-18 Granulos de quetiapina. Expired - Lifetime ES2235941T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922271.3A GB9922271D0 (en) 1999-09-21 1999-09-21 Formulation
GB9922271 1999-09-21

Publications (1)

Publication Number Publication Date
ES2235941T3 true ES2235941T3 (es) 2005-07-16

Family

ID=10861288

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00960855T Expired - Lifetime ES2235941T3 (es) 1999-09-21 2000-09-18 Granulos de quetiapina.

Country Status (37)

Country Link
US (3) US6599897B1 (https=)
EP (1) EP1218009B1 (https=)
JP (1) JP2003509461A (https=)
KR (1) KR100748823B1 (https=)
CN (3) CN1899288A (https=)
AR (1) AR032596A1 (https=)
AT (1) ATE288272T1 (https=)
AU (1) AU776292B2 (https=)
BG (1) BG65469B1 (https=)
BR (1) BR0014107A (https=)
CA (1) CA2383131A1 (https=)
CO (1) CO5180585A1 (https=)
CZ (1) CZ301585B6 (https=)
DE (1) DE60017923T2 (https=)
DK (1) DK1218009T3 (https=)
EE (1) EE200200150A (https=)
EG (1) EG24226A (https=)
ES (1) ES2235941T3 (https=)
GB (2) GB9922271D0 (https=)
HK (1) HK1047706B (https=)
HU (1) HUP0203531A3 (https=)
IL (2) IL148440A0 (https=)
IS (1) IS2139B (https=)
MX (1) MXPA02002627A (https=)
MY (1) MY130208A (https=)
NO (1) NO320908B1 (https=)
NZ (1) NZ517549A (https=)
PL (1) PL198824B1 (https=)
PT (1) PT1218009E (https=)
RU (1) RU2256453C2 (https=)
SI (1) SI1218009T1 (https=)
SK (1) SK286884B6 (https=)
TR (1) TR200200716T2 (https=)
TW (1) TWI226832B (https=)
UA (1) UA73529C2 (https=)
WO (1) WO2001021179A1 (https=)
ZA (1) ZA200201709B (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation
SE0102855D0 (sv) * 2001-08-27 2001-08-27 Astrazeneca Ab Method of treatment
WO2003039516A1 (en) * 2001-11-07 2003-05-15 Fujisawa Pharmaceuticla Co., Ltd. Method for improving dissolution of poorly dispersible medicaments
JP4514473B2 (ja) * 2004-02-23 2010-07-28 富士通株式会社 コンピュータシステム、中央装置及びプログラム実行方法
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
UA88792C2 (ru) * 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
US8048876B2 (en) 2005-04-21 2011-11-01 Medichem S.A. Process for preparing quetiapine and quetiapine fumarate
US20100178333A1 (en) 2006-01-25 2010-07-15 Astron Research Limited Sustained release dosage form of phenothiazine derivatives containing channelizer
TWI389889B (zh) * 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
US8017785B2 (en) * 2006-05-09 2011-09-13 Astrazeneca Ab Salt forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)y1]-4-penten 2-amine
EP2063876A1 (en) * 2006-07-28 2009-06-03 Farmaprojects, S.A. Extended release pharmaceutical formulation of metoprolol and process for its preparation
US20080085888A1 (en) * 2006-09-15 2008-04-10 Breining Scott R Therapeutic Combinations
WO2008052354A1 (en) * 2006-11-03 2008-05-08 University Of Saskatchewan Method of treating demyelination diseases
WO2008091592A1 (en) * 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
DE602007009036D1 (de) 2007-02-14 2010-10-21 Lesvi Laboratorios Sl Pharmazeutische Zusammensetzungen mit Quetiapinfumarat
CN102014655B (zh) * 2008-02-27 2016-01-13 洲际大品牌有限责任公司 多区糖食
EP2262486B1 (en) 2008-08-01 2013-01-02 KRKA, Tovarna Zdravil, D.D., Novo Mesto Quetiapine composition
DE102008046650A1 (de) 2008-09-10 2010-03-11 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Quetiapin enthaltende Retardtablette
CN107714703A (zh) 2009-12-31 2018-02-23 凯姆制药公司 喹硫平的氨基酸缀合物、其制备和使用方法
EP3476218A1 (en) 2010-03-11 2019-05-01 Kempharm, Inc. Fatty acid conjugates of quetiapine, process for making and using the same
US8703802B2 (en) 2010-05-20 2014-04-22 Targacept, Inc. Process for the preparation of aryl substituted olefinic amines
DE102010033527A1 (de) 2010-08-05 2012-02-09 Acino Pharma Ag Quetiapin-Tabletten
DE102011115690A1 (de) 2011-10-11 2013-04-11 Acino Pharma Ag Quetiapin enthaltende Formulierungen
US9993486B1 (en) 2017-06-19 2018-06-12 Tlc Therapeutics, Llc Oral quetiapine suspension formulations with extended shelf life and enhanced bioavailability
EP4142735A4 (en) * 2020-04-29 2024-06-19 Stepan Company SOLID COMPOSITIONS CONTAINING AMINE, PROTONATED AMINE OR QUATERNARY AMMONIUM COMPOUNDS

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound
EP0416773B1 (en) * 1989-08-31 1993-03-03 Takeda Chemical Industries, Ltd. Vitamin b12 composition
IT1250701B (it) * 1991-07-24 1995-04-21 Angelini Francesco Ist Ricerca Composizione farmaceutica solida per uso orale a base di dapiprazolo
JPH06100602A (ja) * 1992-09-18 1994-04-12 Asahi Chem Ind Co Ltd 経口固形製剤およびその製造方法
US5397576A (en) * 1992-09-23 1995-03-14 Hoffmann-La Roche Inc. Spray triturated micronutrient compositions
KR100313649B1 (ko) * 1992-11-09 2002-02-28 더 부츠 캄파니 피엘씨 신경계질환치료제로서유용한1,4-벤조티아제핀,이의제조방법및이를포함하는약제학적조성물
ZA973433B (en) * 1996-04-24 1997-12-10 Shionogi & Co A sertindole-containing preparation and a method for producing the same.
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
GB9611328D0 (en) * 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
ID21762A (id) * 1996-09-24 1999-07-22 Lilly Co Eli Formulasi partikel bersaput
US7919119B2 (en) * 1999-05-27 2011-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation

Also Published As

Publication number Publication date
BG65469B1 (bg) 2008-09-30
EE200200150A (et) 2003-04-15
PL357369A1 (en) 2004-07-26
IS6308A (is) 2002-03-19
NZ517549A (en) 2003-10-31
NO20021394L (no) 2002-03-20
ATE288272T1 (de) 2005-02-15
CZ301585B6 (cs) 2010-04-21
NO20021394D0 (no) 2002-03-20
IL148440A0 (en) 2002-09-12
TR200200716T2 (tr) 2002-06-21
SI1218009T1 (en) 2005-06-30
PL198824B1 (pl) 2008-07-31
PT1218009E (pt) 2005-05-31
GB0021406D0 (en) 2000-10-18
CN1331472C (zh) 2007-08-15
AU776292B2 (en) 2004-09-02
CN1188130C (zh) 2005-02-09
WO2001021179A1 (en) 2001-03-29
KR20020033186A (ko) 2002-05-04
UA73529C2 (uk) 2005-08-15
CN1626094A (zh) 2005-06-15
BR0014107A (pt) 2002-08-20
MY130208A (en) 2007-06-29
HUP0203531A2 (hu) 2003-02-28
DK1218009T3 (da) 2005-05-09
EG24226A (en) 2008-11-10
BG106509A (en) 2002-12-29
NO320908B1 (no) 2006-02-13
AR032596A1 (es) 2003-11-19
CO5180585A1 (es) 2002-07-30
KR100748823B1 (ko) 2007-08-13
CA2383131A1 (en) 2001-03-29
US6599897B1 (en) 2003-07-29
HK1047706B (en) 2005-06-10
GB9922271D0 (en) 1999-11-17
IL148440A (en) 2007-07-04
US20040228914A1 (en) 2004-11-18
DE60017923T2 (de) 2006-01-12
DE60017923D1 (de) 2005-03-10
ZA200201709B (en) 2003-05-28
AU7302300A (en) 2001-04-24
HK1047706A1 (en) 2003-03-07
JP2003509461A (ja) 2003-03-11
EP1218009B1 (en) 2005-02-02
EP1218009A1 (en) 2002-07-03
US20060159768A1 (en) 2006-07-20
IS2139B (is) 2006-08-15
SK3722002A3 (en) 2002-07-02
TWI226832B (en) 2005-01-21
CN1899288A (zh) 2007-01-24
US7022692B2 (en) 2006-04-04
HUP0203531A3 (en) 2004-12-28
MXPA02002627A (es) 2002-07-30
RU2256453C2 (ru) 2005-07-20
SK286884B6 (sk) 2009-07-06
CZ2002974A3 (cs) 2002-06-12
CN1374867A (zh) 2002-10-16

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