ES2227671T3 - Uso de una texafirina en la preparacion de un medicamento para usar con un agente quimioterapeutico en la quimiosensibilizacion del cancer. - Google Patents
Uso de una texafirina en la preparacion de un medicamento para usar con un agente quimioterapeutico en la quimiosensibilizacion del cancer.Info
- Publication number
- ES2227671T3 ES2227671T3 ES97903873T ES97903873T ES2227671T3 ES 2227671 T3 ES2227671 T3 ES 2227671T3 ES 97903873 T ES97903873 T ES 97903873T ES 97903873 T ES97903873 T ES 97903873T ES 2227671 T3 ES2227671 T3 ES 2227671T3
- Authority
- ES
- Spain
- Prior art keywords
- texaphyrin
- iii
- use according
- metal cation
- chemotherapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/591,318 US5776925A (en) | 1996-01-25 | 1996-01-25 | Methods for cancer chemosensitization |
US591318 | 1996-01-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2227671T3 true ES2227671T3 (es) | 2005-04-01 |
Family
ID=24366012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97903873T Expired - Lifetime ES2227671T3 (es) | 1996-01-25 | 1997-01-23 | Uso de una texafirina en la preparacion de un medicamento para usar con un agente quimioterapeutico en la quimiosensibilizacion del cancer. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5776925A (ko) |
EP (1) | EP0912196B9 (ko) |
JP (1) | JP2000503989A (ko) |
KR (1) | KR19990082024A (ko) |
CN (1) | CN1093766C (ko) |
AT (1) | ATE277637T1 (ko) |
AU (1) | AU715025B2 (ko) |
DE (1) | DE69730961T2 (ko) |
ES (1) | ES2227671T3 (ko) |
HK (1) | HK1018588A1 (ko) |
IL (1) | IL125459A0 (ko) |
NO (1) | NO983429L (ko) |
NZ (1) | NZ331513A (ko) |
WO (1) | WO1997026915A1 (ko) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US6482436B1 (en) | 1993-01-29 | 2002-11-19 | Ferx Incorporated | Magnetically responsive composition |
US6200547B1 (en) * | 1994-01-26 | 2001-03-13 | Ferx Incorporated | Magnetically responsive compositions for carrying biologically active substances and methods of production and use |
US5969111A (en) * | 1994-04-14 | 1999-10-19 | Board Of Regents, The University Of Texas System | Texaphyrins substituted with imidazole are provided |
RU2106146C1 (ru) | 1995-07-17 | 1998-03-10 | Институт элементоорганических соединений РАН | Средство для подавления опухолевого роста |
US6441025B2 (en) * | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
JPH10279502A (ja) * | 1997-03-31 | 1998-10-20 | Katsuro Tachibana | 光感受性物質の励起方法 |
US6022526A (en) * | 1997-07-30 | 2000-02-08 | Pharmacyclics, Inc. | Use of texaphyrins in detection of melanin and melanin metabolites diagnostic of melanotic melanoma |
JP4790911B2 (ja) | 1999-01-13 | 2011-10-12 | アルケミア オンコロジー ピーティワイ リミテッド | 薬物の効力を増強するための組成物および方法 |
EP2289549A3 (en) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunoconjugates for treating cancer |
US20030054977A1 (en) * | 1999-10-12 | 2003-03-20 | Cell Therapeutics, Inc. | Manufacture of polyglutamate-therapeutic agent conjugates |
AU1233701A (en) * | 1999-10-29 | 2001-05-14 | Board Of Regents, The University Of Texas System | Methods and compositions for treating atheroma, tumors and other neoplastic tissue |
US7579338B2 (en) * | 1999-10-29 | 2009-08-25 | Pharmacyclics, Inc. | Methods and compositions for treating atheroma, tumors and other neoplastic tissues |
US20030031676A1 (en) * | 1999-10-29 | 2003-02-13 | Pharmacyclics, Inc. | Conjugate compounds for treating atheroma and other diseases |
US20020077290A1 (en) * | 2000-03-17 | 2002-06-20 | Rama Bhatt | Polyglutamic acid-camptothecin conjugates and methods of preparation |
AUPQ879500A0 (en) * | 2000-07-14 | 2000-08-10 | Meditech Research Limited | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease |
US9066919B2 (en) * | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
AU2001290580A1 (en) * | 2000-08-30 | 2002-03-13 | Pharmacyclics, Inc. | Non-symmetric tripyrrannes in the synthesis of novel macrocycles |
US7449454B2 (en) * | 2000-08-30 | 2008-11-11 | Pharmacyclics, Inc. | Metallotexaphyrin derivatives |
US6638924B2 (en) | 2000-08-30 | 2003-10-28 | Pharmacyclics, Inc. | Metallotexaphyrin derivatives |
US20030188326A1 (en) | 2000-11-03 | 2003-10-02 | Dana Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective DNA repair mechanisms and treatment thereof |
JP2004513900A (ja) | 2000-11-17 | 2004-05-13 | ファーマサイクリクス,インコーポレイテッド | テキサフィリン配位化合物およびその使用 |
US20050013853A1 (en) * | 2000-11-29 | 2005-01-20 | Irit Gil-Ad | Anti-proliferative drugs |
IL139975A0 (en) * | 2000-11-29 | 2002-02-10 | Univ Ramot | Anti proliferative drugs |
US6630454B2 (en) | 2001-09-10 | 2003-10-07 | Ramot At Tel-Aviv University Ltd. | Method and pharmaceutical composition for the treatment of cancer |
EP1451343B1 (en) | 2001-11-02 | 2012-10-17 | Dana-Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof |
JP2005511719A (ja) * | 2001-12-13 | 2005-04-28 | ファーマサイクリクス,インコーポレイテッド | 神経性進行に影響を与えるためのプロセス |
CA2469615A1 (en) * | 2001-12-13 | 2003-06-19 | Qing Fan | Combination cancer therapy |
US6984734B2 (en) | 2002-02-26 | 2006-01-10 | Board Of Regents, The University Of Texas System | Cyclo[n]pyrroles and methods thereto |
US6723750B2 (en) | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
US20030224422A1 (en) * | 2002-04-08 | 2003-12-04 | St. Jude Children's Research Hospital, Inc. | Pre-and post therapy gene expression profiling to identify drug targets |
US20040010218A1 (en) * | 2002-07-11 | 2004-01-15 | Henderson Barbara W. | Photodynamic therapy for the enhancement of vascular permeability to aid in drug delivery to diseased tissues |
JP2004077714A (ja) * | 2002-08-15 | 2004-03-11 | Fuji Xerox Co Ltd | 光走査装置 |
US7981928B2 (en) * | 2002-09-05 | 2011-07-19 | Nanodynamics, Inc. | Chemotherapy method using x-rays |
WO2005112759A1 (en) * | 2004-05-20 | 2005-12-01 | Pharmacyclics, Inc. | A method of enhancing visualization of atherosclerotic plaque |
JP2006224318A (ja) * | 2005-02-15 | 2006-08-31 | Brother Ind Ltd | インクジェット記録装置 |
JP4972929B2 (ja) * | 2005-03-25 | 2012-07-11 | ニプロ株式会社 | 放射線増感剤 |
EP1704870A1 (en) | 2005-03-25 | 2006-09-27 | Nipro Corporation | Use of iron compounds as radiosensitizers |
AU2006274509B2 (en) * | 2005-07-27 | 2012-01-19 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
US8319625B2 (en) * | 2005-09-01 | 2012-11-27 | Simplexgrinnell Lp | Fire alarm textual notification related application |
EA013877B1 (ru) * | 2005-09-07 | 2010-08-30 | Алкемиа Онколоджи Пти Лимитед | Терапевтические композиции, содержащие гиалуроновую кислоту и терапевтические антитела, а также способы лечения |
US20070072838A1 (en) * | 2005-09-26 | 2007-03-29 | Pharmacyclics, Inc. | High-purity texaphyrin metal complexes |
US20070078119A1 (en) * | 2005-09-30 | 2007-04-05 | Pharmacyclics, Inc. | Storage system for texaphyrin pharmaceutical formulations |
JP5590882B2 (ja) | 2006-06-26 | 2014-09-17 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | 化学療法増感剤としてのシステインに富む酸性分泌タンパク質(sparc) |
US8287839B2 (en) * | 2006-12-04 | 2012-10-16 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US8444953B2 (en) * | 2007-03-22 | 2013-05-21 | Brookhaven Science Associates, Llc | Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof |
US20080279781A1 (en) * | 2007-05-10 | 2008-11-13 | Brookhaven Science Associates, Llc | Glycosylated Carboranylporphyrins and Uses Thereof |
TWI445696B (zh) | 2010-11-29 | 2014-07-21 | Univ Nat Yang Ming | 標靶人類胸線核苷酸激酶誘導惡性腫瘤中的dna修復毒性 |
US9662328B2 (en) | 2010-11-29 | 2017-05-30 | National Yang-Ming University | Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells |
US10406167B2 (en) | 2014-06-11 | 2019-09-10 | Board Of Regents, The University Of Texas System | Texaphyrin-Pt(IV) conjugates and compositions for use in overcoming platinum resistance |
EP3554475A4 (en) * | 2016-12-13 | 2020-08-19 | Health Research, Inc. | PHOTODYNAMIC THERAPY (PDT) IN THE NEAR INFRARED (NIR) IN COMBINATION WITH CHEMOTHERAPY |
KR20230067608A (ko) | 2020-08-14 | 2023-05-16 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 망간 화학 요법, 광음향 이미징, 및 광열 요법을 위한 텍사피린 유도체 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5559207A (en) * | 1989-03-06 | 1996-09-24 | Board Of Regents, University Of Texas | Texaphyrin metal complex mediated ester hydrolysis |
US5252720A (en) * | 1989-03-06 | 1993-10-12 | Board Of Regents, The University Of Texas System | Metal complexes of water soluble texaphyrins |
US5599923A (en) * | 1989-03-06 | 1997-02-04 | Board Of Regents, University Of Tx | Texaphyrin metal complexes having improved functionalization |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US4935498A (en) * | 1989-03-06 | 1990-06-19 | Board Of Regents, The University Of Texas System | Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
US5258453A (en) * | 1992-01-21 | 1993-11-02 | University Of Utah | Drug delivery system for the simultaneous delivery of drugs activatable by enzymes and light |
US5607924A (en) * | 1992-01-21 | 1997-03-04 | Pharmacyclics, Inc. | DNA photocleavage using texaphyrins |
US5714328A (en) * | 1995-06-07 | 1998-02-03 | Board Of Regents, The University Of Texas System | RNA photocleavage using texaphyrins |
-
1996
- 1996-01-25 US US08/591,318 patent/US5776925A/en not_active Expired - Lifetime
-
1997
- 1997-01-23 WO PCT/US1997/000907 patent/WO1997026915A1/en not_active Application Discontinuation
- 1997-01-23 CN CN97192481A patent/CN1093766C/zh not_active Expired - Fee Related
- 1997-01-23 AT AT97903873T patent/ATE277637T1/de not_active IP Right Cessation
- 1997-01-23 AU AU18333/97A patent/AU715025B2/en not_active Ceased
- 1997-01-23 NZ NZ331513A patent/NZ331513A/en unknown
- 1997-01-23 EP EP97903873A patent/EP0912196B9/en not_active Expired - Lifetime
- 1997-01-23 KR KR1019980705744A patent/KR19990082024A/ko not_active Application Discontinuation
- 1997-01-23 ES ES97903873T patent/ES2227671T3/es not_active Expired - Lifetime
- 1997-01-23 JP JP9526941A patent/JP2000503989A/ja active Pending
- 1997-01-23 DE DE69730961T patent/DE69730961T2/de not_active Expired - Fee Related
-
1998
- 1998-07-22 IL IL12545998A patent/IL125459A0/xx unknown
- 1998-07-24 NO NO983429A patent/NO983429L/no not_active Application Discontinuation
-
1999
- 1999-06-26 HK HK99102732A patent/HK1018588A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL125459A0 (en) | 1999-03-12 |
WO1997026915A1 (en) | 1997-07-31 |
US5776925A (en) | 1998-07-07 |
EP0912196B1 (en) | 2004-09-29 |
EP0912196A1 (en) | 1999-05-06 |
ATE277637T1 (de) | 2004-10-15 |
AU1833397A (en) | 1997-08-20 |
CN1093766C (zh) | 2002-11-06 |
CN1213313A (zh) | 1999-04-07 |
NO983429D0 (no) | 1998-07-24 |
AU715025B2 (en) | 2000-01-13 |
JP2000503989A (ja) | 2000-04-04 |
HK1018588A1 (en) | 1999-12-30 |
EP0912196B9 (en) | 2005-01-05 |
NO983429L (no) | 1998-09-24 |
DE69730961T2 (de) | 2005-11-24 |
KR19990082024A (ko) | 1999-11-15 |
DE69730961D1 (de) | 2004-11-04 |
NZ331513A (en) | 2001-10-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2227671T3 (es) | Uso de una texafirina en la preparacion de un medicamento para usar con un agente quimioterapeutico en la quimiosensibilizacion del cancer. | |
Gill et al. | Transition metal compounds as cancer radiosensitizers | |
ES2321283T3 (es) | Combinaciones de dmxaa y otros agentes anticancerigenos. | |
ES2307867T3 (es) | Preparacion combinada que comprende un derivado de morfolinil antraciclina y un inhibidor de topoisomerasa ii. | |
ES2880291T3 (es) | Nanopartículas conjugadas a un agente antinucleolina | |
US6207660B1 (en) | Texaphyrin conjugates and uses thereof | |
DuRoss et al. | Integrating nanomedicine into clinical radiotherapy regimens | |
JP7184775B2 (ja) | 黄体化ホルモン放出ホルモン受容体(lhrh-r)コンジュゲートおよびその使用 | |
ES2294756T3 (es) | Uso de et743 en terapia de combinacion con dexametasona para el tratamiento del cancer. | |
ES2913119T3 (es) | Cerdulatinib para tratar mieloma | |
Shi et al. | Evolving role of biomaterials in diagnostic and therapeutic radiation oncology | |
EA026168B1 (ru) | Способы лечения рака | |
EP2993983B1 (en) | Targeting corroles for tumor toxicity and mri | |
Wu et al. | Nanofibrillar peptide hydrogels for self-delivery of lonidamine and synergistic photodynamic therapy | |
Liu et al. | Cure of multidrug-resistant human B-cell lymphoma xenografts by combinations of anti-B4-blocked ricin and chemotherapeutic drugs | |
JP2010509241A (ja) | 膜貫通ペプチドからなる自己凝集性ナノ粒子および抗癌剤の特異的腫瘍内送達のためのその利用 | |
US6638924B2 (en) | Metallotexaphyrin derivatives | |
US20170165382A1 (en) | Nanocarriers for cancer treatment | |
KR20210107029A (ko) | 항암제 운반용 입체복합체 | |
CN113179632A (zh) | 原子量子簇的治疗用途 | |
CA2243392C (en) | Use of a texaphyrin in the preparation of a medicament for use with a chemotherapeutic agent in cancer chemosensitization | |
AU775680B2 (en) | Liposome composition and method for administration of a radiosensitizer | |
JP7204744B2 (ja) | c(RGD-ACP-K)修飾血中滞留型リポソーム | |
Sarfaraz et al. | Nanotechnology and it’s therapeutic application-a review | |
McGuire et al. | Phase II study of esorubicin (4′-deozydoxorubicin) in advanced epithelial carcinoma of the ovary: A Gynecologic Oncology Group study |