ES2218806T3 - Sialilacion practica in vitro de glicoproteinas recombinantes. - Google Patents
Sialilacion practica in vitro de glicoproteinas recombinantes.Info
- Publication number
- ES2218806T3 ES2218806T3 ES98904583T ES98904583T ES2218806T3 ES 2218806 T3 ES2218806 T3 ES 2218806T3 ES 98904583 T ES98904583 T ES 98904583T ES 98904583 T ES98904583 T ES 98904583T ES 2218806 T3 ES2218806 T3 ES 2218806T3
- Authority
- ES
- Spain
- Prior art keywords
- sialyltransferase
- glycoprotein
- sialylation
- sialic acid
- recombinant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 108090000288 Glycoproteins Proteins 0.000 claims abstract description 135
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- 238000000034 method Methods 0.000 claims abstract description 85
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims abstract description 48
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| AU736993B2 (en) * | 1997-01-16 | 2001-08-09 | Novo Nordisk A/S | Practical in vitro sialylation of recombinant glycoproteins |
| US6689604B1 (en) | 1998-03-20 | 2004-02-10 | National Research Council Of Canada | Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses |
| PT1137789E (pt) | 1998-12-09 | 2010-10-21 | Phyton Holdings Llc | Um método para produzir glicoproteínas possuindo glicosilação de tipo humano |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
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- 1998-01-15 JP JP51870998A patent/JP2001507215A/ja not_active Withdrawn
- 1998-01-15 IL IL13096498A patent/IL130964A0/xx not_active IP Right Cessation
- 1998-01-15 DE DE69823046T patent/DE69823046T2/de not_active Expired - Fee Related
- 1998-01-15 DK DK98904583T patent/DK1015622T3/da active
- 1998-01-15 EP EP98904583A patent/EP1015622B1/en not_active Expired - Lifetime
- 1998-01-15 WO PCT/US1998/000835 patent/WO1998031826A1/en not_active Ceased
- 1998-01-15 AT AT98904583T patent/ATE263841T1/de not_active IP Right Cessation
- 1998-01-15 US US09/007,741 patent/US6399336B1/en not_active Expired - Lifetime
- 1998-01-15 ES ES98904583T patent/ES2218806T3/es not_active Expired - Lifetime
- 1998-01-15 NZ NZ336780A patent/NZ336780A/xx unknown
- 1998-01-15 CA CA2278178A patent/CA2278178C/en not_active Expired - Fee Related
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- 2001-11-09 US US10/007,331 patent/US20020119516A1/en not_active Abandoned
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- 2002-02-21 US US10/081,456 patent/US20020160460A1/en not_active Abandoned
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| US20020142370A1 (en) | 2002-10-03 |
| IL130964A (en) | 2006-06-11 |
| US20030124645A1 (en) | 2003-07-03 |
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| DE69823046D1 (de) | 2004-05-13 |
| DE69823046T2 (de) | 2005-03-31 |
| US6399336B1 (en) | 2002-06-04 |
| EP1015622B1 (en) | 2004-04-07 |
| CA2278178A1 (en) | 1998-07-23 |
| AU6242798A (en) | 1998-08-07 |
| JP2011024597A (ja) | 2011-02-10 |
| EP1015622A1 (en) | 2000-07-05 |
| CA2278178C (en) | 2012-09-25 |
| IL130964A0 (en) | 2001-01-28 |
| ATE263841T1 (de) | 2004-04-15 |
| US20020119516A1 (en) | 2002-08-29 |
| EP1015622A4 (en) | 2002-06-19 |
| WO1998031826A1 (en) | 1998-07-23 |
| AU736993B2 (en) | 2001-08-09 |
| JP2001507215A (ja) | 2001-06-05 |
| US7220555B2 (en) | 2007-05-22 |
| DK1015622T3 (da) | 2004-08-02 |
| US20020160460A1 (en) | 2002-10-31 |
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