ES2207868T3 - Metodo que usa un calibrador y un dispositivo y kit de ensayo que incluye el calibrador. - Google Patents
Metodo que usa un calibrador y un dispositivo y kit de ensayo que incluye el calibrador.Info
- Publication number
- ES2207868T3 ES2207868T3 ES98965943T ES98965943T ES2207868T3 ES 2207868 T3 ES2207868 T3 ES 2207868T3 ES 98965943 T ES98965943 T ES 98965943T ES 98965943 T ES98965943 T ES 98965943T ES 2207868 T3 ES2207868 T3 ES 2207868T3
- Authority
- ES
- Spain
- Prior art keywords
- calibrator
- reagent
- analyte
- matrix
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title claims abstract description 90
- 238000012360 testing method Methods 0.000 title description 19
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 236
- 239000012491 analyte Substances 0.000 claims abstract description 116
- 239000011159 matrix material Substances 0.000 claims abstract description 108
- 238000001514 detection method Methods 0.000 claims abstract description 60
- 230000008569 process Effects 0.000 claims abstract description 42
- 230000027455 binding Effects 0.000 claims abstract description 38
- 239000007788 liquid Substances 0.000 claims abstract description 19
- 239000011230 binding agent Substances 0.000 claims abstract description 13
- 238000006243 chemical reaction Methods 0.000 claims abstract description 13
- 239000002245 particle Substances 0.000 claims description 87
- 238000011144 upstream manufacturing Methods 0.000 claims description 25
- 239000000872 buffer Substances 0.000 claims description 21
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- 238000004458 analytical method Methods 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 206010020751 Hypersensitivity Diseases 0.000 claims description 3
- 230000007815 allergy Effects 0.000 claims description 3
- 208000023275 Autoimmune disease Diseases 0.000 claims description 2
- 208000026935 allergic disease Diseases 0.000 claims 1
- 238000003149 assay kit Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
- 239000000523 sample Substances 0.000 description 54
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 16
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 15
- 239000012528 membrane Substances 0.000 description 14
- 239000000126 substance Substances 0.000 description 14
- 239000004793 Polystyrene Substances 0.000 description 12
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 12
- 238000005859 coupling reaction Methods 0.000 description 12
- 229920002223 polystyrene Polymers 0.000 description 12
- 230000008878 coupling Effects 0.000 description 11
- 238000010168 coupling process Methods 0.000 description 11
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 9
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 8
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 8
- 229910052799 carbon Inorganic materials 0.000 description 8
- 239000011780 sodium chloride Substances 0.000 description 8
- 238000003756 stirring Methods 0.000 description 8
- 108010090804 Streptavidin Proteins 0.000 description 7
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 235000018185 Betula X alpestris Nutrition 0.000 description 5
- 235000018212 Betula X uliginosa Nutrition 0.000 description 5
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- 229930006000 Sucrose Natural products 0.000 description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 4
- 235000017557 sodium bicarbonate Nutrition 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 239000005720 sucrose Substances 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 3
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
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- 238000004873 anchoring Methods 0.000 description 3
- 235000003704 aspartic acid Nutrition 0.000 description 3
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 3
- 230000007717 exclusion Effects 0.000 description 3
- 235000013922 glutamic acid Nutrition 0.000 description 3
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- 230000001900 immune effect Effects 0.000 description 3
- 102000018358 immunoglobulin Human genes 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
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- 230000036963 noncompetitive effect Effects 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000002285 radioactive effect Effects 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- WBOURNUBSRYUJE-UHFFFAOYSA-M 4-(dimethylamino)pyridin-1-ium-1-carbonitrile;bromide Chemical compound [Br-].CN(C)C1=CC=[N+](C#N)C=C1 WBOURNUBSRYUJE-UHFFFAOYSA-M 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 239000012131 assay buffer Substances 0.000 description 2
- 230000006287 biotinylation Effects 0.000 description 2
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- 231100000673 dose–response relationship Toxicity 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000005111 flow chemistry technique Methods 0.000 description 2
- -1 for example Polymers 0.000 description 2
- 108010074605 gamma-Globulins Proteins 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
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- 239000002184 metal Substances 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 235000009109 Betula pendula Nutrition 0.000 description 1
- 241000219430 Betula pendula Species 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 235000010724 Wisteria floribunda Nutrition 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 125000003172 aldehyde group Chemical group 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 150000001720 carbohydrates Chemical group 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 229910052681 coesite Inorganic materials 0.000 description 1
- 238000012875 competitive assay Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000001268 conjugating effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
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- 229910052906 cristobalite Inorganic materials 0.000 description 1
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- 238000013461 design Methods 0.000 description 1
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- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000003891 environmental analysis Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 108091008039 hormone receptors Proteins 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- REKHIPAOQFESGJ-UHFFFAOYSA-N hydroxy(sulfo)carbamic acid Chemical group C(=O)(O)N(S(O)(=O)=O)O REKHIPAOQFESGJ-UHFFFAOYSA-N 0.000 description 1
- 230000000984 immunochemical effect Effects 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
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- 239000004005 microsphere Substances 0.000 description 1
- 239000003068 molecular probe Substances 0.000 description 1
- 150000002772 monosaccharides Chemical group 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000021309 simple sugar Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 229910052682 stishovite Inorganic materials 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- 150000005846 sugar alcohols Chemical class 0.000 description 1
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- 238000012546 transfer Methods 0.000 description 1
- 229910052905 tridymite Inorganic materials 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Test And Diagnosis Of Digital Computers (AREA)
- Debugging And Monitoring (AREA)
- Techniques For Improving Reliability Of Storages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704933 | 1997-12-30 | ||
| SE9704933A SE9704933D0 (sv) | 1997-12-30 | 1997-12-30 | Metod som utnyttjar en ny kalibrator och test kit som innehåller kalibratorn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2207868T3 true ES2207868T3 (es) | 2004-06-01 |
Family
ID=20409627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98965943T Expired - Lifetime ES2207868T3 (es) | 1997-12-30 | 1998-12-30 | Metodo que usa un calibrador y un dispositivo y kit de ensayo que incluye el calibrador. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6916666B1 (https=) |
| EP (1) | EP1044373B1 (https=) |
| JP (1) | JP4331895B2 (https=) |
| AT (1) | ATE249626T1 (https=) |
| AU (1) | AU748059B2 (https=) |
| CA (1) | CA2314872C (https=) |
| DE (1) | DE69818104T2 (https=) |
| DK (1) | DK1044373T3 (https=) |
| ES (1) | ES2207868T3 (https=) |
| PT (1) | PT1044373E (https=) |
| SE (1) | SE9704933D0 (https=) |
| WO (1) | WO1999036777A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60238699D1 (de) * | 2001-09-17 | 2011-02-03 | Phadia Ab | Mehrfachanalytassay-vorrichtung mit multi-spot-nachweiszone |
| BR0215327A (pt) * | 2001-12-24 | 2006-06-06 | Kimberly Clark Co | sistema de calibração interna para ensaios de circulação de fluxo |
| US20030119203A1 (en) * | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
| US6837171B1 (en) | 2002-04-29 | 2005-01-04 | Palmer/Snyder Furniture Company | Lightweight table with unitized table top |
| US7285424B2 (en) * | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
| US7314763B2 (en) | 2002-08-27 | 2008-01-01 | Kimberly-Clark Worldwide, Inc. | Fluidics-based assay devices |
| US7432105B2 (en) | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
| US20040092036A1 (en) * | 2002-09-11 | 2004-05-13 | Lattec I/S | Device for analysing analyte compounds and use hereof |
| US7781172B2 (en) | 2003-11-21 | 2010-08-24 | Kimberly-Clark Worldwide, Inc. | Method for extending the dynamic detection range of assay devices |
| US20040121334A1 (en) * | 2002-12-19 | 2004-06-24 | Kimberly-Clark Worldwide, Inc. | Self-calibrated flow-through assay devices |
| US7247500B2 (en) | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
| US7851209B2 (en) | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
| US20040197819A1 (en) | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
| US8101429B2 (en) | 2003-06-03 | 2012-01-24 | Siemens Healthcare Diagnostics Inc. | Native analyte as a reference in lateral flow assays |
| EP1646862B1 (en) * | 2003-06-03 | 2018-04-11 | Siemens Healthcare Diagnostics Inc. | Automatic identification of reagent test strips using reflectance values |
| WO2005031355A1 (en) | 2003-09-22 | 2005-04-07 | Quidel Corporation | Devices for the detection of multiple analytes in a sample |
| US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
| US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
| US20050112703A1 (en) | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
| ATE449337T1 (de) * | 2003-12-12 | 2009-12-15 | Inverness Medical Switzerland | Assay |
| US7943089B2 (en) | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
| US7521226B2 (en) | 2004-06-30 | 2009-04-21 | Kimberly-Clark Worldwide, Inc. | One-step enzymatic and amine detection technique |
| US7906276B2 (en) | 2004-06-30 | 2011-03-15 | Kimberly-Clark Worldwide, Inc. | Enzymatic detection techniques |
| CA2475456A1 (en) | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to optimize analyte and antibody substrate binding by least energy adsorption |
| CA2475240A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to measure dynamic internal calibration true dose response curves |
| US8101415B2 (en) * | 2005-07-05 | 2012-01-24 | Bayer Healthcare Llc | Calibration system for use with lateral flow assay test strips |
| WO2007149043A1 (en) * | 2006-06-20 | 2007-12-27 | Åmic AB | Assay device |
| CA2647953A1 (en) * | 2008-12-29 | 2010-06-29 | Sqi Diagnostics Systems Inc. | Multiplex analyte detection |
| DE102009010563A1 (de) | 2009-02-16 | 2010-08-26 | Matthias W. Engel | Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten |
| DE102009037791A1 (de) * | 2009-08-17 | 2011-02-24 | Dst Diagnostische Systeme & Technologien Gmbh | Testsystem zur visuellen Auswertung |
| US20120214230A1 (en) * | 2009-10-22 | 2012-08-23 | Ge Healthcare Bio-Sciences Ab | Cell culture/handling product and method for production and use thereof |
| US8486717B2 (en) | 2011-01-18 | 2013-07-16 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| AU2012309203B2 (en) * | 2011-09-14 | 2017-08-10 | Phadia Ab | Calibration reagent and method |
| US9874556B2 (en) | 2012-07-18 | 2018-01-23 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| US20140072959A1 (en) | 2012-09-12 | 2014-03-13 | Force Diagnostics, Inc. | Rapid tests for insurance underwriting |
| CN105102980B (zh) | 2013-02-26 | 2017-11-03 | 阿斯图特医药公司 | 具有试条保持件的横向流动测定法 |
| CN108051590B (zh) | 2013-09-13 | 2020-12-11 | Symbolics有限责任公司 | 运用二维试验和对照信号读出模式的侧向层析检测 |
| BR112017021305A2 (pt) | 2015-04-06 | 2018-06-26 | Bludiagnostics Inc | dispositivo de teste de fluxo lateral, e, método e kit para detecção quantitativa de um analito em uma amostra de saliva |
| WO2018039047A1 (en) | 2016-08-23 | 2018-03-01 | Qoolabs, Inc. | Lateral flow assay for assessing recombinant protein expression or reporter gene expression |
| KR102582297B1 (ko) | 2017-05-19 | 2023-09-25 | 필립모리스 프로덕츠 에스.에이. | 대상체의 흡연 상태를 구별하기 위한 진단 테스트 |
| EP3910335A1 (en) * | 2020-05-11 | 2021-11-17 | Koninklijke Philips N.V. | Calibration using a regenerative surface |
| US20220268765A1 (en) * | 2021-02-22 | 2022-08-25 | Waters Technologies Corporation | Methods and kits for universal calibration of lateral flow testing |
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| US4446231A (en) * | 1979-10-03 | 1984-05-01 | Self Colin H | Immunoassay using an amplified cyclic detection system |
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| DE3445816C1 (de) | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flaechenfoermiges diagnostisches Mittel |
| US4740468A (en) * | 1985-02-14 | 1988-04-26 | Syntex (U.S.A.) Inc. | Concentrating immunochemical test device and method |
| CA1272127A (en) | 1985-04-04 | 1990-07-31 | Hybritech Incorporated | Solid phase system for use in ligand-receptor assays |
| JPS62231168A (ja) * | 1986-03-21 | 1987-10-09 | ハイブリテツク・インコ−ポレイテツド | アナライト−レセプタ−分析用内部標準を設けるための改良法 |
| JPS63253464A (ja) | 1987-04-10 | 1988-10-20 | Hitachi Ltd | 計画作成支援システム |
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| DE3856421T2 (de) | 1987-04-27 | 2000-12-14 | Unilever Nv | Spezifische Bindungstestverfahren |
| US5120643A (en) | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
| US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
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-
1997
- 1997-12-30 SE SE9704933A patent/SE9704933D0/xx unknown
-
1998
- 1998-12-30 WO PCT/SE1998/002464 patent/WO1999036777A1/en not_active Ceased
- 1998-12-30 DE DE69818104T patent/DE69818104T2/de not_active Expired - Lifetime
- 1998-12-30 AT AT98965943T patent/ATE249626T1/de active
- 1998-12-30 AU AU21950/99A patent/AU748059B2/en not_active Expired
- 1998-12-30 PT PT98965943T patent/PT1044373E/pt unknown
- 1998-12-30 DK DK98965943T patent/DK1044373T3/da active
- 1998-12-30 EP EP98965943A patent/EP1044373B1/en not_active Expired - Lifetime
- 1998-12-30 CA CA002314872A patent/CA2314872C/en not_active Expired - Lifetime
- 1998-12-30 JP JP2000540438A patent/JP4331895B2/ja not_active Expired - Lifetime
- 1998-12-30 US US09/582,741 patent/US6916666B1/en not_active Expired - Lifetime
- 1998-12-30 ES ES98965943T patent/ES2207868T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU748059B2 (en) | 2002-05-30 |
| SE9704933D0 (sv) | 1997-12-30 |
| AU2195099A (en) | 1999-08-02 |
| DE69818104D1 (de) | 2003-10-16 |
| CA2314872A1 (en) | 1999-07-22 |
| ATE249626T1 (de) | 2003-09-15 |
| US6916666B1 (en) | 2005-07-12 |
| PT1044373E (pt) | 2003-12-31 |
| EP1044373B1 (en) | 2003-09-10 |
| DE69818104T2 (de) | 2004-07-15 |
| JP2002509252A (ja) | 2002-03-26 |
| WO1999036777A1 (en) | 1999-07-22 |
| EP1044373A1 (en) | 2000-10-18 |
| CA2314872C (en) | 2009-04-14 |
| JP4331895B2 (ja) | 2009-09-16 |
| DK1044373T3 (da) | 2004-01-12 |
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