ES2092523T3 - Ensayos que utilizan enlaces con recuperacion de conjugado. - Google Patents
Ensayos que utilizan enlaces con recuperacion de conjugado.Info
- Publication number
- ES2092523T3 ES2092523T3 ES91106593T ES91106593T ES2092523T3 ES 2092523 T3 ES2092523 T3 ES 2092523T3 ES 91106593 T ES91106593 T ES 91106593T ES 91106593 T ES91106593 T ES 91106593T ES 2092523 T3 ES2092523 T3 ES 2092523T3
- Authority
- ES
- Spain
- Prior art keywords
- conjugate
- analytics
- recovery
- place
- test sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000011084 recovery Methods 0.000 title abstract 4
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
LOS NUEVOS DISPOSITIVOS ANALITICOS Y METODOS DE ESTA INVENCION INCLUYEN UN MATERIAL DE FASE SOLIDA, TAL COMO UNA TIRA DE ENSAYO, A TRAVES DE LA CUAL UNA MUESTRA DE ENSAYO Y UN CONJUGADO VIAJAN Y CONTACTAN SECUENCIALMENTE AL MENOS DOS LUGARES DEFINIDOS PARA LA MUESTRA COMPARATIVA DE CONJUGADOS INMOVILIZADOS. LOS DOS LUGARES DEFINIDOS DE ESTA INVENCION INCLUYEN UN LUGAR DE CAPTURA AL CUAL ES UNIDO UN REACTIVO CAPTURADO Y UN LUGAR DE RECUPERACION CONJUGADO AL CUAL SE UNE UN REACTIVO DE RECUPERACION CONJUGADO. LA INMOVILIZACION DE CONJUGADOS EN ESTOS LUGARES ES RELATIVA A LA CANTIDAD DE ANALITICOS EN LA MUESTRA DE ENSAYO. CUANDO SE INCREMENTA LA CANTIDAD DE ANALITICOS EN LA MUESTRA, HAY UN DECRECIMIENTO EN LOS CONJUGADOS DETECTABLES EN EL LUGAR DE CAPTURA Y UN INCREMENTO CORRESPONDIENTE EN CONJUGADOS DETECTABLES EN EL LUGAR DE RECUPERACION DE CONJUGADOS. EL DISPOSITIVO Y LOS METODOS PUEDEN USARSE PARA DETECTAR LA PRESENCIA O CANTIDAD DE ANALITICA EN UNA MUESTRA DE ENSAYO CONTENIENDO O SOSPECHOSA DE CONTENER EL ANALITICO DE INTERES. OPCIONALMENTE SE PUEDE USAR UN CONJUGADO POLIVALENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52105390A | 1990-05-09 | 1990-05-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2092523T3 true ES2092523T3 (es) | 1996-12-01 |
Family
ID=24075136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91106593T Expired - Lifetime ES2092523T3 (es) | 1990-05-09 | 1991-04-24 | Ensayos que utilizan enlaces con recuperacion de conjugado. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0462376B1 (es) |
JP (1) | JPH04230857A (es) |
KR (1) | KR920005766A (es) |
AT (1) | ATE140794T1 (es) |
AU (1) | AU637489B2 (es) |
CA (1) | CA2041782A1 (es) |
DE (1) | DE69121021T2 (es) |
ES (1) | ES2092523T3 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6472160B2 (en) | 1919-09-08 | 2002-10-29 | Fujirebio Inc. | Immunoassay device and immunoassay method using the same |
AU659754B2 (en) * | 1992-09-04 | 1995-05-25 | Becton Dickinson & Company | Chromatographic antigen sandwich test for detection of specific antibody and device therefor |
AU660837B2 (en) * | 1992-09-04 | 1995-07-06 | Becton Dickinson & Company | Indirect chromatographic antigen sandwich test for detection of specific antibody and device therefor |
EP1701164B1 (en) * | 1997-07-16 | 2009-03-11 | Charm Sciences Inc. | Method for detecting the presence of a residue analyte in a sample |
US6436721B1 (en) | 1997-07-25 | 2002-08-20 | Bayer Corporation | Device and method for obtaining clinically significant analyte ratios |
SE9704933D0 (sv) | 1997-12-30 | 1997-12-30 | Pharmacia & Upjohn Diag Ab | Metod som utnyttjar en ny kalibrator och test kit som innehåller kalibratorn |
SE9704935D0 (sv) | 1997-12-30 | 1997-12-30 | Pharmacia & Upjohn Diag Ab | Analysmetod med partiklar |
US7713703B1 (en) | 2000-11-13 | 2010-05-11 | Biosite, Inc. | Methods for monitoring the status of assays and immunoassays |
US6183972B1 (en) | 1998-07-27 | 2001-02-06 | Bayer Corporation | Method for the determination of analyte concentration in a lateral flow sandwich immunoassay exhibiting high-dose hook effect |
US7640083B2 (en) | 2002-11-22 | 2009-12-29 | Monroe David A | Record and playback system for aircraft |
FR2788856B1 (fr) * | 1999-01-21 | 2001-07-13 | Adiatec Sa | Dispositif de test et procede pour la quantification de resultats obtenus par des methodes immunochromatographiques |
US6297020B1 (en) | 1999-03-01 | 2001-10-02 | Bayer Corporation | Device for carrying out lateral-flow assays involving more than one analyte |
SE0002820L (sv) * | 2000-08-04 | 2002-02-05 | Jordanian Pharmaceutical Mfg & | Medicinskt kit |
US6837171B1 (en) | 2002-04-29 | 2005-01-04 | Palmer/Snyder Furniture Company | Lightweight table with unitized table top |
US20030119203A1 (en) | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
EP1493029B1 (en) * | 2002-04-10 | 2010-03-31 | Response Biomedical Corporation | Sensitive immunochromatographic assay |
US7285424B2 (en) | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
US7247500B2 (en) | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
FR2853077B1 (fr) * | 2003-03-28 | 2005-12-30 | Vedalab | Procedes immunochromatographiques en phase solide |
US7851209B2 (en) | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
US20040197819A1 (en) | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
US8101429B2 (en) | 2003-06-03 | 2012-01-24 | Siemens Healthcare Diagnostics Inc. | Native analyte as a reference in lateral flow assays |
WO2005031351A1 (en) * | 2003-09-23 | 2005-04-07 | Oakville Hong Kong Co., Limited | Lateral flow assay devices and methods of use |
US20050112703A1 (en) | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
US7943089B2 (en) | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
US7521226B2 (en) | 2004-06-30 | 2009-04-21 | Kimberly-Clark Worldwide, Inc. | One-step enzymatic and amine detection technique |
GB2433989B (en) | 2004-07-01 | 2009-04-08 | Central Science Lab | Analyte detection system |
US7910381B2 (en) * | 2005-10-13 | 2011-03-22 | BioAssay Works | Immuno gold lateral flow assay |
EP2041567A4 (en) * | 2006-07-09 | 2011-04-13 | Infigo Diagnostics Ltd | QUICK DIAGNOSIS DEVICES BASED ON MOLECULAR PRESCRIPTION POLYMERS |
WO2008106021A1 (en) | 2007-02-26 | 2008-09-04 | Response Biomedical Corporation | Comparative multiple analyte assay |
GB0717043D0 (en) | 2007-04-10 | 2007-10-10 | Inverness Medical Switzerland | Assay device |
GB2460660B (en) | 2008-06-04 | 2013-05-22 | Alere Switzerland Gmbh | Assay reader device & method for measuring hCG |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4746631A (en) * | 1985-05-09 | 1988-05-24 | Ultra Diagnostics Corporation | Immunoassay method, device, and test kit |
JPS62231168A (ja) * | 1986-03-21 | 1987-10-09 | ハイブリテツク・インコ−ポレイテツド | アナライト−レセプタ−分析用内部標準を設けるための改良法 |
CA1303983C (en) * | 1987-03-27 | 1992-06-23 | Robert W. Rosenstein | Solid phase assay |
US5120643A (en) * | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
WO1991005262A1 (en) * | 1989-10-02 | 1991-04-18 | University Of Michigan | Bioanalytical detection system |
-
1991
- 1991-04-24 EP EP91106593A patent/EP0462376B1/en not_active Expired - Lifetime
- 1991-04-24 ES ES91106593T patent/ES2092523T3/es not_active Expired - Lifetime
- 1991-04-24 AT AT91106593T patent/ATE140794T1/de not_active IP Right Cessation
- 1991-04-24 DE DE69121021T patent/DE69121021T2/de not_active Expired - Fee Related
- 1991-04-26 AU AU75986/91A patent/AU637489B2/en not_active Ceased
- 1991-05-03 CA CA002041782A patent/CA2041782A1/en not_active Abandoned
- 1991-05-08 KR KR1019910007398A patent/KR920005766A/ko not_active IP Right Cessation
- 1991-05-09 JP JP3104167A patent/JPH04230857A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0462376A3 (en) | 1992-08-05 |
ATE140794T1 (de) | 1996-08-15 |
CA2041782A1 (en) | 1991-11-10 |
DE69121021T2 (de) | 1997-02-27 |
AU637489B2 (en) | 1993-05-27 |
DE69121021D1 (de) | 1996-08-29 |
KR920005766A (ko) | 1992-04-03 |
JPH04230857A (ja) | 1992-08-19 |
EP0462376A2 (en) | 1991-12-27 |
AU7598691A (en) | 1991-11-14 |
EP0462376B1 (en) | 1996-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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