ES2203449T3 - Tratamiento de la hipertension pulmonar por inhalacion de prostaglandinas de bencindeno. - Google Patents
Tratamiento de la hipertension pulmonar por inhalacion de prostaglandinas de bencindeno.Info
- Publication number
- ES2203449T3 ES2203449T3 ES00920253T ES00920253T ES2203449T3 ES 2203449 T3 ES2203449 T3 ES 2203449T3 ES 00920253 T ES00920253 T ES 00920253T ES 00920253 T ES00920253 T ES 00920253T ES 2203449 T3 ES2203449 T3 ES 2203449T3
- Authority
- ES
- Spain
- Prior art keywords
- pulmonary
- administration
- bencindene
- intravenously
- inhalation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12499999P | 1999-03-18 | 1999-03-18 | |
| US124999P | 1999-03-18 |
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| ES2203449T3 true ES2203449T3 (es) | 2004-04-16 |
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| EP (1) | EP1161234B1 (OSRAM) |
| JP (2) | JP4819224B2 (OSRAM) |
| KR (1) | KR100750384B1 (OSRAM) |
| CN (1) | CN1196479C (OSRAM) |
| AT (1) | ATE245979T1 (OSRAM) |
| AU (1) | AU4082700A (OSRAM) |
| CA (1) | CA2365890C (OSRAM) |
| DE (1) | DE60004181T2 (OSRAM) |
| DK (1) | DK1161234T3 (OSRAM) |
| ES (1) | ES2203449T3 (OSRAM) |
| PT (1) | PT1161234E (OSRAM) |
| WO (1) | WO2000054758A2 (OSRAM) |
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| US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
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| RU2593016C2 (ru) * | 2014-12-15 | 2016-07-27 | Федеральное государственное бюджетное учреждение науки Институт теоретической и прикладной механики им. С.А. Христиановича Сибирского отделения Российской академии наук (ИТПМ СО РАН) | Способ лечения артериальной гипертензии путем ингаляционного введения аэрозоля гипотензивного препарата |
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| JP7455144B2 (ja) | 2019-04-29 | 2024-03-25 | インスメッド インコーポレイテッド | トレプロスチニルプロドラッグの乾燥粉末組成物およびその使用方法 |
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| CN115916212A (zh) | 2020-04-17 | 2023-04-04 | 联合治疗公司 | 曲前列尼尔用于治疗间质性肺病 |
| AU2021289336B2 (en) | 2020-06-09 | 2025-08-28 | Mannkind Corporation | Fumaryl diketopiperidine prodrugs of treprostinil |
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| CN117479946A (zh) | 2021-03-03 | 2024-01-30 | 联合治疗公司 | 含曲前列环素及其前药并还包含(e)-3,6-双[4-(n-羰基-2-丙烯基)酰胺丁基]-2,5-二酮哌嗪(fdkp)的干粉组合物 |
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| US4338457A (en) * | 1980-02-28 | 1982-07-06 | The Upjohn Company | Composition and process |
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-
2000
- 2000-03-15 US US09/525,471 patent/US6521212B1/en not_active Expired - Lifetime
- 2000-03-17 AU AU40827/00A patent/AU4082700A/en not_active Abandoned
- 2000-03-17 ES ES00920253T patent/ES2203449T3/es not_active Expired - Lifetime
- 2000-03-17 AT AT00920253T patent/ATE245979T1/de active
- 2000-03-17 DE DE60004181T patent/DE60004181T2/de not_active Expired - Lifetime
- 2000-03-17 CN CNB008051089A patent/CN1196479C/zh not_active Expired - Lifetime
- 2000-03-17 JP JP2000604834A patent/JP4819224B2/ja not_active Expired - Lifetime
- 2000-03-17 KR KR1020017011610A patent/KR100750384B1/ko not_active Expired - Lifetime
- 2000-03-17 CA CA2365890A patent/CA2365890C/en not_active Expired - Lifetime
- 2000-03-17 PT PT00920253T patent/PT1161234E/pt unknown
- 2000-03-17 DK DK00920253T patent/DK1161234T3/da active
- 2000-03-17 WO PCT/US2000/040040 patent/WO2000054758A2/en not_active Ceased
- 2000-03-17 EP EP00920253A patent/EP1161234B1/en not_active Expired - Lifetime
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2002
- 2002-08-06 US US10/212,149 patent/US6756033B2/en not_active Expired - Lifetime
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2011
- 2011-05-30 JP JP2011119894A patent/JP2011201907A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60004181T2 (de) | 2004-04-15 |
| US6521212B1 (en) | 2003-02-18 |
| WO2000054758A3 (en) | 2001-02-08 |
| DK1161234T3 (da) | 2003-11-24 |
| JP4819224B2 (ja) | 2011-11-24 |
| AU4082700A (en) | 2000-10-04 |
| KR20010108352A (ko) | 2001-12-07 |
| EP1161234B1 (en) | 2003-07-30 |
| JP2011201907A (ja) | 2011-10-13 |
| JP2002539154A (ja) | 2002-11-19 |
| US6756033B2 (en) | 2004-06-29 |
| DE60004181D1 (de) | 2003-09-04 |
| ATE245979T1 (de) | 2003-08-15 |
| CN1196479C (zh) | 2005-04-13 |
| KR100750384B1 (ko) | 2007-08-17 |
| US20030053958A1 (en) | 2003-03-20 |
| CN1379665A (zh) | 2002-11-13 |
| CA2365890C (en) | 2010-09-21 |
| CA2365890A1 (en) | 2000-09-21 |
| EP1161234A2 (en) | 2001-12-12 |
| PT1161234E (pt) | 2003-12-31 |
| WO2000054758A2 (en) | 2000-09-21 |
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