ES2188953T3 - Procedimiento para la preparacion de ftalidas. - Google Patents

Procedimiento para la preparacion de ftalidas.

Info

Publication number
ES2188953T3
ES2188953T3 ES97928217T ES97928217T ES2188953T3 ES 2188953 T3 ES2188953 T3 ES 2188953T3 ES 97928217 T ES97928217 T ES 97928217T ES 97928217 T ES97928217 T ES 97928217T ES 2188953 T3 ES2188953 T3 ES 2188953T3
Authority
ES
Spain
Prior art keywords
pct
ftalidas
procedure
preparation
phthalide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97928217T
Other languages
English (en)
Inventor
Klemens Massonne
Rainer Becker
Wolfgang Reif
Horst Neuhauser
Andreas Gieseler
Klaus Mundinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2188953T3 publication Critical patent/ES2188953T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE UN PROCEDIMIENTO PARA LA OBTENCION DE FTALUROS DE FORMULA GENERAL I, EN LA CUAL R 1 , R 2 , R 3 Y R 4 SON, INDEPENDIENTEMENTE UNO DEL OTRO, HIDROGENO, ALQUILO DE C 1 -C 4 O ALCOXI DE C SUB,1 -C 4 , MEDIANTE HIDROGENACION CATALITICA DE ANHIDRIDOS DE ACIDO FTALICO DE FORMULA GENERAL (II), EN LA CUAL LOS RADICALES R 1 , R 2 , R 3 Y R 4 TIENEN LOS SIGNIF ICADOS CITADOS ANTES, EN UN DISOLVENTE EN EL CUAL EL FTALURO (I), EL CUAL SE FORMA COMO PRODUCTO DE LA HIDROGENACION CATALITICA, SE UTILIZA COMO DISOLVENTE.
ES97928217T 1996-07-03 1997-06-17 Procedimiento para la preparacion de ftalidas. Expired - Lifetime ES2188953T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19626659A DE19626659A1 (de) 1996-07-03 1996-07-03 Verfahren zur Herstellung von Phthaliden

Publications (1)

Publication Number Publication Date
ES2188953T3 true ES2188953T3 (es) 2003-07-01

Family

ID=7798741

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97928217T Expired - Lifetime ES2188953T3 (es) 1996-07-03 1997-06-17 Procedimiento para la preparacion de ftalidas.

Country Status (11)

Country Link
US (1) US6028204A (es)
EP (1) EP0912540B1 (es)
JP (1) JP2000513726A (es)
CN (1) CN1075496C (es)
AT (1) ATE229517T1 (es)
DE (2) DE19626659A1 (es)
DK (1) DK0912540T3 (es)
ES (1) ES2188953T3 (es)
PT (1) PT912540E (es)
TW (1) TW455585B (es)
WO (1) WO1998001437A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA002977B1 (ru) 1998-10-20 2002-12-26 Х.Лундбекк А/С Способ получения циталопрама
WO2000039112A1 (en) 1998-12-23 2000-07-06 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) * 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
WO2000012044A2 (en) 1999-10-25 2000-03-09 H. Lundbeck A/S Method for the preparation of citalopram
ATE355268T1 (de) 1999-10-25 2006-03-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
SI1246812T1 (en) 1999-12-28 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
WO2001049672A1 (en) 1999-12-30 2001-07-12 H. Lundbeck A/S Method for the preparation of citalopram
CZ20022601A3 (cs) * 2000-01-14 2002-10-16 H. Lundbeck A/S Způsob výroby 5-kyanoftalidu
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EP1265883A1 (en) * 2000-03-13 2002-12-18 H. Lundbeck A/S Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EA200200968A1 (ru) * 2000-03-13 2003-02-27 Х.Лундбекк А/С Поэтапное алкилирование 5-замещенных 1-(4-фторфенил)-1,3-дигидроизобензофуранов
PT1265882E (pt) 2000-03-14 2004-06-30 Lundbeck & Co As H Metodo para preparacao de citalopram; composto e citalopram
CN1418206A (zh) * 2000-03-16 2003-05-14 H·隆德贝克有限公司 5－氰基－1－(4－氟苯基)－1,3－二氢异苯并呋喃的制备方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CN1182127C (zh) * 2000-06-28 2004-12-29 中国医学科学院药物研究所 新的取代的2-苯并[c]呋喃酮化合物,其制备方法以及包含它们的药物组合物
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
IL147226A (en) 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure cithalopram
ATE222899T1 (de) * 2000-12-28 2002-09-15 Lundbeck & Co As H Verfahren zur herstellung von reinem citalopram
AU2003214582A1 (en) * 2003-04-11 2004-11-01 Bromine Compounds Ltd. Process for the preparation of 5-bromophthalide
CN101302209B (zh) * 2008-06-13 2011-05-04 浙江工业大学 一种金基催化剂作用下苯酐液相加氢制备苯酞的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2114696A (en) * 1935-03-30 1938-04-19 Du Pont Process of producing phthalide
US2079325A (en) * 1935-03-30 1937-05-04 Du Pont Process for the preparation of lactones
DE2803319C2 (de) * 1978-01-26 1986-11-13 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Phthalid
DE3201300A1 (de) * 1982-01-18 1983-07-28 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur herstellung von phthalid
DE4136992A1 (de) * 1991-11-11 1993-05-13 Basf Ag Verfahren zur herstellung von phthaliden

Also Published As

Publication number Publication date
WO1998001437A1 (de) 1998-01-15
TW455585B (en) 2001-09-21
DE19626659A1 (de) 1998-01-08
PT912540E (pt) 2003-04-30
CN1075496C (zh) 2001-11-28
CN1216987A (zh) 1999-05-19
DE59708958D1 (de) 2003-01-23
ATE229517T1 (de) 2002-12-15
EP0912540B1 (de) 2002-12-11
DK0912540T3 (da) 2003-01-06
JP2000513726A (ja) 2000-10-17
US6028204A (en) 2000-02-22
EP0912540A1 (de) 1999-05-06

Similar Documents

Publication Publication Date Title
ES2188953T3 (es) Procedimiento para la preparacion de ftalidas.
ATE231140T1 (de) Verfahren zur herstellung von phthaliden
ATE191218T1 (de) Rapamycin-derivate als immunosuppressoren
ATE168416T1 (de) Zellfreie synthese und isolierung von genen und polypeptiden
BR9306794A (pt) Uso de zeólito beta contendo titánio como catalisador zeólito beta contendo titánio e processo para a produção de ácido adípico
ES2153202T3 (es) Derivado de 2-cloro-3,5-bis(trifluorometil)fenilbenzoil-urea y procedimiento para su preparacion.
ES2158511T3 (es) Procedimiento para la obtencion de ftaluros.
HUP0101322A2 (hu) Eljárás ciklohexilidén-aminok cisz-szelektív katalitikus hidrogénezésére
TR199801039T2 (xx) Yeni fenilamidin t�revlerinin elde edilmesine y�nelik usul.
AU8252787A (en) Process for the preparation of thienylethylamines and novel dithienylethylamines
NO991633D0 (no) FremgangsmÕte ved biotransformasjon av kolkisinforbindelser til de tilsvarende 3-glykosyl-derivater
ATE276986T1 (de) Verfahren zur herstellung von tetrahydrofuran
HUP9903481A1 (hu) Eljárás 1-aril-1-ciano-ciklobután-származékok előállítására
HUP0002351A2 (hu) Eljárás N-izoxazolil-bifenilszulfonamidok előállítására, köztitermékeik és eljárás ezek előállítására
DE60003807D1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
ES2153196T3 (es) Procedimiento para la obtencion de derivados del acido 2-fluor-1-ciclopropanocarboxilico por deshalogenacion reductora.
ATE131155T1 (de) Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidine.
ES2175337T3 (es) Compuesto bifenilicos y su utilizacion como agentes estrogenicos.
PT937094E (pt) Processo para a preparacao de ivermectina
IL109728A0 (en) Indoles
BR9301786A (pt) Processo para preparacao de 5-cloroxin-dol,e processo para preparacao de alquilesteres de acido cloronitrobenzenoacetico
ATE244217T1 (de) Herstellung von beta-mehtylcarbapenem- zwischenprodukten
DE3584791D1 (de) Verfahren zur herstellung von indolinen.
ES2126920T3 (es) Procedimiento para la obtencion de o-(2-hidroxialquil)-oximas.
MX9706960A (es) Proceso para sintetizar acidos benzoicos.