ES2188953T3 - Procedimiento para la preparacion de ftalidas. - Google Patents
Procedimiento para la preparacion de ftalidas.Info
- Publication number
- ES2188953T3 ES2188953T3 ES97928217T ES97928217T ES2188953T3 ES 2188953 T3 ES2188953 T3 ES 2188953T3 ES 97928217 T ES97928217 T ES 97928217T ES 97928217 T ES97928217 T ES 97928217T ES 2188953 T3 ES2188953 T3 ES 2188953T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- ftalidas
- procedure
- preparation
- phthalide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION TRATA DE UN PROCEDIMIENTO PARA LA OBTENCION DE FTALUROS DE FORMULA GENERAL I, EN LA CUAL R 1 , R 2 , R 3 Y R 4 SON, INDEPENDIENTEMENTE UNO DEL OTRO, HIDROGENO, ALQUILO DE C 1 -C 4 O ALCOXI DE C SUB,1 -C 4 , MEDIANTE HIDROGENACION CATALITICA DE ANHIDRIDOS DE ACIDO FTALICO DE FORMULA GENERAL (II), EN LA CUAL LOS RADICALES R 1 , R 2 , R 3 Y R 4 TIENEN LOS SIGNIF ICADOS CITADOS ANTES, EN UN DISOLVENTE EN EL CUAL EL FTALURO (I), EL CUAL SE FORMA COMO PRODUCTO DE LA HIDROGENACION CATALITICA, SE UTILIZA COMO DISOLVENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19626659A DE19626659A1 (de) | 1996-07-03 | 1996-07-03 | Verfahren zur Herstellung von Phthaliden |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2188953T3 true ES2188953T3 (es) | 2003-07-01 |
Family
ID=7798741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97928217T Expired - Lifetime ES2188953T3 (es) | 1996-07-03 | 1997-06-17 | Procedimiento para la preparacion de ftalidas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6028204A (es) |
EP (1) | EP0912540B1 (es) |
JP (1) | JP2000513726A (es) |
CN (1) | CN1075496C (es) |
AT (1) | ATE229517T1 (es) |
DE (2) | DE19626659A1 (es) |
DK (1) | DK0912540T3 (es) |
ES (1) | ES2188953T3 (es) |
PT (1) | PT912540E (es) |
TW (1) | TW455585B (es) |
WO (1) | WO1998001437A1 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1129592C (zh) | 1998-10-20 | 2003-12-03 | H·隆德贝克有限公司 | 制备西酞普兰的方法 |
ES2195644T3 (es) | 1998-12-23 | 2003-12-01 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida. |
AR022329A1 (es) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida |
EP1173431B2 (en) * | 1999-04-14 | 2009-08-26 | H. Lundbeck A/S | Method for the preparation of citalopram |
ITMI991579A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
ITMI991581A1 (it) * | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
PT1228056E (pt) | 1999-10-25 | 2005-02-28 | Lundbeck & Co As H | Metodo de preparacao de citaloprame |
AU742554B2 (en) | 1999-10-25 | 2002-01-03 | H. Lundbeck A/S | Method for the preparation of citalopram |
AR026063A1 (es) * | 1999-11-01 | 2002-12-26 | Lundbeck & Co As H | Metodo para la preparacion de 5-carboxiftalida. |
AU778751B2 (en) | 1999-12-28 | 2004-12-16 | H. Lundbeck A/S | Method for the preparation of citalopram |
DK1246813T3 (da) | 1999-12-30 | 2004-03-01 | Lundbeck & Co As H | Fremgangsmåde til fremstilling af Citalopram |
TR200201783T2 (tr) * | 2000-01-14 | 2002-12-23 | H. Lundbeck A/S | 5-Siyanofatalid hazırlamak için yöntem |
NL1017415C1 (nl) | 2000-02-24 | 2001-05-18 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
NL1017417C1 (nl) | 2000-03-03 | 2001-03-16 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
JP2003527385A (ja) * | 2000-03-13 | 2003-09-16 | ハー・ルンドベック・アクチエゼルスカベット | 5−置換された1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフランの段階的アルキル化法 |
IES20010206A2 (en) | 2000-03-13 | 2002-03-06 | Lundbeck & Co As H | Method for the preparation of citalopram |
IL151490A0 (en) | 2000-03-13 | 2003-04-10 | Lundbeck & Co As H | Method for the preparation of citalopram |
TR200400611T4 (tr) | 2000-03-14 | 2004-04-21 | H.Lundbeck A/S | Sitalopramın preparasyon metodu |
CZ20023406A3 (cs) * | 2000-03-16 | 2003-01-15 | H. Lundbeck A/S | Způsob výroby 5-kyano-1-(4-fluorfenyl)-1,3-dihydroisobenzofuranu |
AR032455A1 (es) | 2000-05-12 | 2003-11-12 | Lundbeck & Co As H | Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva |
CN1182127C (zh) * | 2000-06-28 | 2004-12-29 | 中国医学科学院药物研究所 | 新的取代的2-苯并[c]呋喃酮化合物,其制备方法以及包含它们的药物组合物 |
CA2354877C (en) | 2000-08-18 | 2006-05-02 | H. Lundbeck A/S | Method for the preparation of citalopram |
EP1462447A3 (en) | 2000-12-22 | 2004-11-17 | H. Lundbeck A/S | Method for the preparation of pure citalopram |
AU3920201A (en) * | 2000-12-28 | 2001-07-09 | H. Lundbeck A/S | Process for the preparation of pure citalopram |
WO2004089924A1 (en) * | 2003-04-11 | 2004-10-21 | Bromine Compounds Ltd. | Process for the preparation of 5-bromophthalide |
CN101302209B (zh) * | 2008-06-13 | 2011-05-04 | 浙江工业大学 | 一种金基催化剂作用下苯酐液相加氢制备苯酞的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2079325A (en) * | 1935-03-30 | 1937-05-04 | Du Pont | Process for the preparation of lactones |
US2114696A (en) * | 1935-03-30 | 1938-04-19 | Du Pont | Process of producing phthalide |
DE2803319C2 (de) * | 1978-01-26 | 1986-11-13 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von Phthalid |
DE3201300A1 (de) * | 1982-01-18 | 1983-07-28 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur herstellung von phthalid |
DE4136992A1 (de) * | 1991-11-11 | 1993-05-13 | Basf Ag | Verfahren zur herstellung von phthaliden |
-
1996
- 1996-07-03 DE DE19626659A patent/DE19626659A1/de not_active Withdrawn
-
1997
- 1997-06-17 EP EP97928217A patent/EP0912540B1/de not_active Expired - Lifetime
- 1997-06-17 CN CN97194213A patent/CN1075496C/zh not_active Expired - Fee Related
- 1997-06-17 PT PT97928217T patent/PT912540E/pt unknown
- 1997-06-17 ES ES97928217T patent/ES2188953T3/es not_active Expired - Lifetime
- 1997-06-17 AT AT97928217T patent/ATE229517T1/de not_active IP Right Cessation
- 1997-06-17 DE DE59708958T patent/DE59708958D1/de not_active Expired - Fee Related
- 1997-06-17 US US09/202,478 patent/US6028204A/en not_active Expired - Fee Related
- 1997-06-17 WO PCT/EP1997/003137 patent/WO1998001437A1/de active IP Right Grant
- 1997-06-17 DK DK97928217T patent/DK0912540T3/da active
- 1997-06-17 JP JP10504700A patent/JP2000513726A/ja not_active Withdrawn
- 1997-07-03 TW TW086109390A patent/TW455585B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK0912540T3 (da) | 2003-01-06 |
CN1216987A (zh) | 1999-05-19 |
CN1075496C (zh) | 2001-11-28 |
WO1998001437A1 (de) | 1998-01-15 |
US6028204A (en) | 2000-02-22 |
TW455585B (en) | 2001-09-21 |
DE19626659A1 (de) | 1998-01-08 |
ATE229517T1 (de) | 2002-12-15 |
EP0912540A1 (de) | 1999-05-06 |
JP2000513726A (ja) | 2000-10-17 |
DE59708958D1 (de) | 2003-01-23 |
EP0912540B1 (de) | 2002-12-11 |
PT912540E (pt) | 2003-04-30 |
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