ES2185374T3 - Procedimiento de modulacion tisular para el analisis espectroscopico cuantitativo in vivo, no invasor de tejidos. - Google Patents

Procedimiento de modulacion tisular para el analisis espectroscopico cuantitativo in vivo, no invasor de tejidos.

Info

Publication number
ES2185374T3
ES2185374T3 ES99933705T ES99933705T ES2185374T3 ES 2185374 T3 ES2185374 T3 ES 2185374T3 ES 99933705 T ES99933705 T ES 99933705T ES 99933705 T ES99933705 T ES 99933705T ES 2185374 T3 ES2185374 T3 ES 2185374T3
Authority
ES
Spain
Prior art keywords
spectra
tissue
region
collected
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99933705T
Other languages
English (en)
Inventor
Joseph Chaiken
Charles M Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LighTouch Medical Inc
Original Assignee
LighTouch Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LighTouch Medical Inc filed Critical LighTouch Medical Inc
Application granted granted Critical
Publication of ES2185374T3 publication Critical patent/ES2185374T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/655—Stimulated Raman

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Un método no invasor para determinar la concentración de un analito en sangre de un sujeto, que comprende: a) irradiar una región de tejido del sujeto con un manantial de luz; b) recoger los espectros de fluorescencia emitidos por la región de tejido, siendo la cantidad de espectros de fluorescencia indicadora del volumen de sangre; c) recoger los espectros de Raman emitidos por la región de tejido para un margen de longitudes de onda que corresponda al analito, siendo la cantidad de espectros de Raman indicadora de la cantidad de analito; y d) dividir los espectros de Raman recogidos por los espectros de fluorescencia recogidos, para obtener un número proporcional a la concentración de analito por unidad de volumen de sangre.
ES99933705T 1998-07-07 1999-07-07 Procedimiento de modulacion tisular para el analisis espectroscopico cuantitativo in vivo, no invasor de tejidos. Expired - Lifetime ES2185374T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9189998P 1998-07-07 1998-07-07

Publications (1)

Publication Number Publication Date
ES2185374T3 true ES2185374T3 (es) 2003-04-16

Family

ID=22230207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99933705T Expired - Lifetime ES2185374T3 (es) 1998-07-07 1999-07-07 Procedimiento de modulacion tisular para el analisis espectroscopico cuantitativo in vivo, no invasor de tejidos.

Country Status (9)

Country Link
US (1) US6289230B1 (es)
EP (1) EP1094746B1 (es)
JP (1) JP4486253B2 (es)
AT (1) ATE225142T1 (es)
AU (1) AU4970499A (es)
CA (1) CA2333565C (es)
DE (1) DE69903306T2 (es)
ES (1) ES2185374T3 (es)
WO (1) WO2000001295A1 (es)

Families Citing this family (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6389306B1 (en) * 1998-04-24 2002-05-14 Lightouch Medical, Inc. Method for determining lipid and protein content of tissue
JP2000155090A (ja) * 1998-11-20 2000-06-06 Fuji Photo Film Co Ltd 血管の画像化装置
DE19937699C1 (de) * 1999-08-10 2001-11-22 Ges Foerderung Spektrochemie Verfahren und Vorrichtung zur nichtinvasiven Messung von Blutbestandteilen und klinischen Parametern
US20090059203A1 (en) * 2000-03-17 2009-03-05 Wei-Kung Wang Apparatus For Measuring Concentration of a Specific Ingredient In-Situ
US7389132B2 (en) * 2000-03-17 2008-06-17 Wei-Kung Wang Mold-in method and apparatus
US20060211931A1 (en) * 2000-05-02 2006-09-21 Blank Thomas B Noninvasive analyzer sample probe interface method and apparatus
US7519406B2 (en) * 2004-04-28 2009-04-14 Sensys Medical, Inc. Noninvasive analyzer sample probe interface method and apparatus
US7606608B2 (en) * 2000-05-02 2009-10-20 Sensys Medical, Inc. Optical sampling interface system for in-vivo measurement of tissue
DE10027100C2 (de) * 2000-05-31 2002-08-08 Klaus Mueller-Dethlefs Verfahren und Vorrichtung zum Nachweisen von Substanzen in Körperflüssigkeiten
US7050842B2 (en) * 2000-07-11 2006-05-23 Lightouch Medical, Inc. Method of tissue modulation for noninvasive measurement of an analyte
CA2435282A1 (en) * 2001-01-19 2002-07-25 General Instrument Corporation Voice menu controlled self-diagnostic method
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US20050187439A1 (en) * 2003-03-07 2005-08-25 Blank Thomas B. Sampling interface system for in-vivo estimation of tissue analyte concentration
US7697966B2 (en) * 2002-03-08 2010-04-13 Sensys Medical, Inc. Noninvasive targeting system method and apparatus
US8718738B2 (en) 2002-03-08 2014-05-06 Glt Acquisition Corp. Method and apparatus for coupling a sample probe with a sample site
US20070149868A1 (en) * 2002-03-08 2007-06-28 Blank Thomas B Method and Apparatus for Photostimulation Enhanced Analyte Property Estimation
US20050054908A1 (en) * 2003-03-07 2005-03-10 Blank Thomas B. Photostimulation method and apparatus in combination with glucose determination
EP1499231A4 (en) * 2002-03-08 2007-09-26 Sensys Medical Inc COMPACT DEVICE FOR NONINVASIVE MEASUREMENT OF GLUCOSE BY NEAR-INFRARED SPECTROSCOPY
US8504128B2 (en) * 2002-03-08 2013-08-06 Glt Acquisition Corp. Method and apparatus for coupling a channeled sample probe to tissue
CN1327812C (zh) 2002-03-25 2007-07-25 Tyt技研株式会社 不抽血的血液成分值测量装置
US7725144B2 (en) * 2002-04-04 2010-05-25 Veralight, Inc. Determination of disease state using raman spectroscopy of tissue
US8131332B2 (en) * 2002-04-04 2012-03-06 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites
US6711426B2 (en) 2002-04-09 2004-03-23 Spectros Corporation Spectroscopy illuminator with improved delivery efficiency for high optical density and reduced thermal load
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
JP2007518443A (ja) * 2003-07-09 2007-07-12 グルコン インク 装着可能なグルコメータ
US20050043597A1 (en) * 2003-07-31 2005-02-24 Skymoon Research And Development, Llc Optical vivo probe of analyte concentration within the sterile matrix under the human nail
US7266401B2 (en) * 2003-08-22 2007-09-04 C8 Medisensors Inc. Measuring analytes from an electromagnetic spectrum using a wavelength router
US20070234300A1 (en) * 2003-09-18 2007-10-04 Leake David W Method and Apparatus for Performing State-Table Driven Regression Testing
US20050187438A1 (en) * 2004-02-24 2005-08-25 Skymoon Research & Development, Llc Anti-stokes raman in vivo probe of analyte concentrations through the human nail
US8868147B2 (en) * 2004-04-28 2014-10-21 Glt Acquisition Corp. Method and apparatus for controlling positioning of a noninvasive analyzer sample probe
US20080033275A1 (en) * 2004-04-28 2008-02-07 Blank Thomas B Method and Apparatus for Sample Probe Movement Control
AT413446B (de) * 2004-07-05 2006-02-15 Austria Wirtschaftsserv Gmbh Verfahren und einrichtung zum durchführen von raman-spektroskopie
US20060063992A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes
US20060063993A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes
US20060063991A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes with dynamic spectral calibration
US8234923B2 (en) 2004-09-20 2012-08-07 Innervision Medical Technologies Inc. Systems and methods for ultrasound imaging
GB0426993D0 (en) 2004-12-09 2005-01-12 Council Cent Lab Res Councils Apparatus for depth-selective raman spectroscopy
US20080306363A1 (en) * 2005-01-06 2008-12-11 Lightouch Medical, Inc. Specialized Human Servo Device And Process For Tissue Modulation Of Human Fingerprints
US20060217602A1 (en) * 2005-03-04 2006-09-28 Alan Abul-Haj Method and apparatus for noninvasive targeting
US20060211926A1 (en) * 2005-03-21 2006-09-21 Dejin Yu Non-invasive Raman measurement apparatus with broadband spectral correction
JP5001934B2 (ja) * 2005-04-15 2012-08-15 バイエル・ヘルスケア・エルエルシー 体内グルコースを測定する非侵襲的システム及び方法
WO2006127766A1 (en) * 2005-05-25 2006-11-30 Bayer Healthcare Llc Methods of using raman spectral information in determining analyte concentrations
US7330747B2 (en) * 2005-06-07 2008-02-12 Chemimage Corporation Invasive chemometry
US7330746B2 (en) * 2005-06-07 2008-02-12 Chem Image Corporation Non-invasive biochemical analysis
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
US7813778B2 (en) 2005-07-29 2010-10-12 Spectros Corporation Implantable tissue ischemia sensor
EP2260756A1 (de) * 2005-08-09 2010-12-15 Flore, Ingo Medizinische Messvorrichtung
US8855738B2 (en) * 2005-08-18 2014-10-07 University Of Rochester Acoustically induced blood stasis and in vivo optical spectroscopy
EP1760440A1 (en) * 2005-08-31 2007-03-07 The Procter and Gamble Company Confocal raman spectroscopy for dermatological studies
US7914451B2 (en) * 2005-09-15 2011-03-29 Innervision Medical Technologies Inc. Determining attributes using ultrasound
EP1928302B1 (en) 2005-09-30 2012-08-01 Intuity Medical, Inc. Fully integrated wearable or handheld monitor
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
US7558619B2 (en) * 2005-10-04 2009-07-07 Nu Skin International, Inc. Raman instrument for measuring weak signals in the presence of strong background fluorescence
GB0606891D0 (en) * 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
WO2007092054A2 (en) 2006-02-06 2007-08-16 Specht Donald F Method and apparatus to visualize the coronary arteries using ultrasound
DE102006021343A1 (de) * 2006-05-05 2007-11-08 Mevitec Gmbh Vorrichtung zur optischen Untersuchung eines biologischen Gewebes
US20100030480A1 (en) * 2006-05-05 2010-02-04 Jahn Wolfgang Device and method for examination and evaluation of a biological active and/or biological activatable substance
EP1890133B1 (de) * 2006-08-16 2016-10-12 F. Hoffmann-La Roche AG Verfahren zum Untersuchen einer Probe einer Flüssigkeit
US7603151B2 (en) * 2006-08-22 2009-10-13 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
EP2077748A2 (en) * 2006-08-22 2009-07-15 Bayer Healthcare, LLC A method for correcting a spectral image for optical aberrations using software
EP2088932B1 (en) 2006-10-25 2020-04-08 Maui Imaging, Inc. Method and apparatus to produce ultrasonic images using multiple apertures
EP2076172A4 (en) * 2006-10-27 2012-03-21 Aretais Inc USE OF COHERENT RAMAN PROCEDURES FOR MEDICAL DIAGNOSTIC AND THERAPEUTIC PURPOSES AND CALIBRATION METHOD THEREFOR
EP2096989B1 (de) * 2006-11-23 2012-11-21 Flore, Ingo Medizinische messvorrichtung
US8157730B2 (en) 2006-12-19 2012-04-17 Valencell, Inc. Physiological and environmental monitoring systems and methods
US8652040B2 (en) 2006-12-19 2014-02-18 Valencell, Inc. Telemetric apparatus for health and environmental monitoring
WO2008085411A2 (en) * 2006-12-27 2008-07-17 Valencell, Inc. Multi-wavelength optical devices and methods of using same
KR100871074B1 (ko) * 2007-02-01 2008-11-28 삼성전자주식회사 비침습형 혈당 측정 장치 및 그 방법
KR101312259B1 (ko) * 2007-02-09 2013-09-25 삼성전자주식회사 박막 트랜지스터 및 그 제조방법
US7672702B2 (en) * 2007-03-13 2010-03-02 Samsung Electronics Co., Ltd. Noninvasive in vivo measuring system and noninvasive in vivo measuring method by correcting influence of Hemoglobin
US20090036759A1 (en) * 2007-08-01 2009-02-05 Ault Timothy E Collapsible noninvasive analyzer method and apparatus
EP2183382A1 (en) * 2007-08-08 2010-05-12 Chemimage Corporation Raman difference spectra based disease classification
WO2009033625A1 (de) * 2007-09-07 2009-03-19 Flore, Ingo Medizinische messvorrichtung zur bioelektrischen impedanzmessung
WO2009045374A2 (en) * 2007-09-28 2009-04-09 University Of Florida Research Foundation Inc. Novel methods and devices for noninvasive measurement of energy absorbers in blood
US9282945B2 (en) 2009-04-14 2016-03-15 Maui Imaging, Inc. Calibration of ultrasound probes
US8251903B2 (en) 2007-10-25 2012-08-28 Valencell, Inc. Noninvasive physiological analysis using excitation-sensor modules and related devices and methods
US9833183B2 (en) 2008-05-30 2017-12-05 Intuity Medical, Inc. Body fluid sampling device—sampling site interface
US8260402B2 (en) * 2008-06-06 2012-09-04 Longevity Link, Inc. Noninvasive measurement of carotenoids in biological tissue
CN101292875B (zh) * 2008-06-06 2010-07-14 天津市先石光学技术有限公司 利用基准波长测量成分浓度的方法
EP3639744B1 (en) 2008-06-06 2021-11-24 Intuity Medical, Inc. Blood glucose meter and method of operating
WO2009148624A1 (en) 2008-06-06 2009-12-10 Intuity Medical, Inc. Detection meter and mode of operation
US9814417B2 (en) * 2009-01-13 2017-11-14 Longevity Link Corporation Noninvasive measurement of flavonoid compounds in biological tissue
US8788002B2 (en) 2009-02-25 2014-07-22 Valencell, Inc. Light-guiding devices and monitoring devices incorporating same
EP3127476A1 (en) 2009-02-25 2017-02-08 Valencell, Inc. Light-guiding devices and monitoring devices incorporating same
US9750462B2 (en) 2009-02-25 2017-09-05 Valencell, Inc. Monitoring apparatus and methods for measuring physiological and/or environmental conditions
DE102009011381A1 (de) 2009-03-05 2010-09-09 Flore, Ingo, Dr. Diagnostische Messvorrichtung
KR101659723B1 (ko) 2009-04-14 2016-09-26 마우이 이미징, 인코포레이티드 복수 개구 초음파 어레이 정렬 설비
US8538499B2 (en) * 2009-09-23 2013-09-17 Lightouch Medical, Inc. Process and apparatus for non-invasive, continuous in vivo measurement of hematocrit
WO2011065981A1 (en) 2009-11-30 2011-06-03 Intuity Medical, Inc. Calibration material delivery devices and methods
US9603559B2 (en) 2009-12-24 2017-03-28 Children's Medical Center Corporation Capillary refill time diagnostic apparatus and methods
EP2536339B1 (en) 2010-02-18 2024-05-15 Maui Imaging, Inc. Point source transmission and speed-of-sound correction using multi-aperture ultrasound imaging
JP5441781B2 (ja) * 2010-03-25 2014-03-12 キヤノン株式会社 光音響イメージング装置、光音響イメージング方法及びプログラム
US8235897B2 (en) 2010-04-27 2012-08-07 A.D. Integrity Applications Ltd. Device for non-invasively measuring glucose
WO2011162823A1 (en) 2010-06-25 2011-12-29 Intuity Medical, Inc. Analyte monitoring methods and systems
US9662047B2 (en) 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
US10292589B2 (en) * 2010-09-20 2019-05-21 California Institute Of Technology Acoustic-assisted iterative wave form optimization for deep tissue focusing
US10216893B2 (en) 2010-09-30 2019-02-26 Fitbit, Inc. Multimode sensor devices
EP3563768A3 (en) 2010-10-13 2020-02-12 Maui Imaging, Inc. Concave ultrasound transducers and 3d arrays
WO2012051305A2 (en) 2010-10-13 2012-04-19 Mau Imaging, Inc. Multiple aperture probe internal apparatus and cable assemblies
US8888701B2 (en) 2011-01-27 2014-11-18 Valencell, Inc. Apparatus and methods for monitoring physiological data during environmental interference
WO2013016007A2 (en) 2011-07-25 2013-01-31 Valencell, Inc. Apparatus and methods for estimating time-state physiological parameters
EP2739207B1 (en) 2011-08-02 2017-07-19 Valencell, Inc. Systems and methods for variable filter adjustment by heart rate metric feedback
EP3750480B1 (en) 2011-08-03 2022-02-02 Intuity Medical, Inc. Body fluid sampling arrangement
JP6407719B2 (ja) 2011-12-01 2018-10-17 マウイ イマギング，インコーポレーテッド ピングベース及び多数開口ドップラー超音波を用いた運動の検出
JP2015503404A (ja) 2011-12-29 2015-02-02 マウイ イマギング，インコーポレーテッド 任意経路のｍモード超音波イメージング
CN104135937B (zh) 2012-02-21 2017-03-29 毛伊图像公司 使用多孔超声确定材料刚度
EP2833791B1 (en) 2012-03-26 2022-12-21 Maui Imaging, Inc. Methods for improving ultrasound image quality by applying weighting factors
US9044149B2 (en) 2012-06-22 2015-06-02 Fitbit, Inc. Heart rate data collection
US8948832B2 (en) * 2012-06-22 2015-02-03 Fitbit, Inc. Wearable heart rate monitor
US9005129B2 (en) 2012-06-22 2015-04-14 Fitbit, Inc. Wearable heart rate monitor
US9049998B2 (en) 2012-06-22 2015-06-09 Fitbit, Inc. Biometric monitoring device with heart rate measurement activated by a single user-gesture
IN2015DN00556A (es) 2012-08-10 2015-06-26 Maui Imaging Inc
EP3893022A1 (en) 2012-09-06 2021-10-13 Maui Imaging, Inc. Ultrasound imaging system memory architecture
KR101390090B1 (ko) * 2012-09-18 2014-05-27 한국과학기술원 카메라를 이용한 사용자 단말 센싱장치, 이를 이용한 센싱방법 및 제어방법
US9039614B2 (en) 2013-01-15 2015-05-26 Fitbit, Inc. Methods, systems and devices for measuring fingertip heart rate
ITMI20130104A1 (it) * 2013-01-24 2014-07-25 Empatica Srl Dispositivo, sistema e metodo per la rilevazione e il trattamento di segnali di battito cardiaco
EP2928364A4 (en) 2013-01-28 2015-11-11 Valencell Inc DEVICES FOR MONITORING PHYSIOLOGICAL FUNCTIONS WITH SENSOR ELEMENTS DIVIDED FROM BODY MOVEMENTS
US9510806B2 (en) 2013-03-13 2016-12-06 Maui Imaging, Inc. Alignment of ultrasound transducer arrays and multiple aperture probe assembly
JP2016522070A (ja) 2013-06-21 2016-07-28 インテュイティ メディカル インコーポレイテッド 可聴フィードバックを用いた分析物モニタリングシステム
US10512407B2 (en) 2013-06-24 2019-12-24 Fitbit, Inc. Heart rate data collection
US9883848B2 (en) 2013-09-13 2018-02-06 Maui Imaging, Inc. Ultrasound imaging using apparent point-source transmit transducer
WO2015104158A1 (de) 2014-01-07 2015-07-16 Opsolution Gmbh Vorrichtung und verfahren zur bestimmung einer konzentration in einer probe
US9538921B2 (en) 2014-07-30 2017-01-10 Valencell, Inc. Physiological monitoring devices with adjustable signal analysis and interrogation power and monitoring methods using same
EP3199100A1 (en) 2014-08-06 2017-08-02 Valencell, Inc. Earbud with a physiological information sensor module
KR102617888B1 (ko) 2014-08-18 2023-12-22 마우이 이미징, 인코포레이티드 네트워크-기반 초음파 이미징 시스템
US10709365B2 (en) 2014-08-21 2020-07-14 I. R. Med Ltd. System and method for noninvasive analysis of subcutaneous tissue
US10772541B2 (en) * 2014-08-21 2020-09-15 I. R. Med Ltd. System and method for noninvasive analysis of subcutaneous tissue
US9794653B2 (en) 2014-09-27 2017-10-17 Valencell, Inc. Methods and apparatus for improving signal quality in wearable biometric monitoring devices
GB201503911D0 (en) 2015-03-09 2015-04-22 Renishaw Plc Transmission raman spectroscopy
US9392946B1 (en) 2015-05-28 2016-07-19 Fitbit, Inc. Heart rate sensor with high-aspect-ratio photodetector element
US10610158B2 (en) 2015-10-23 2020-04-07 Valencell, Inc. Physiological monitoring devices and methods that identify subject activity type
US10945618B2 (en) 2015-10-23 2021-03-16 Valencell, Inc. Physiological monitoring devices and methods for noise reduction in physiological signals based on subject activity type
EP3170446A1 (de) * 2015-11-20 2017-05-24 NIRLUS Engineering AG Verfahren und vorrichtung zur nichtinvasiven optischen in-vivo-bestimmung der glukosekonzentration in fliessendem blut
US11206989B2 (en) 2015-12-10 2021-12-28 Fitbit, Inc. Light field management in an optical biological parameter sensor
US10568525B1 (en) 2015-12-14 2020-02-25 Fitbit, Inc. Multi-wavelength pulse oximetry
JP2019506205A (ja) 2015-12-31 2019-03-07 ウェア２ビー リミテッド 生理学的測定値の非侵襲的監視のための装置、システム、および方法
EP3408037A4 (en) 2016-01-27 2019-10-23 Maui Imaging, Inc. ULTRASONIC IMAGING WITH DISTRIBUTED NETWORK PROBES
US10433739B2 (en) 2016-04-29 2019-10-08 Fitbit, Inc. Multi-channel photoplethysmography sensor
WO2018009736A1 (en) 2016-07-08 2018-01-11 Valencell, Inc. Motion-dependent averaging for physiological metric estimating systems and methods
US11051706B1 (en) 2017-04-07 2021-07-06 Fitbit, Inc. Multiple source-detector pair photoplethysmography (PPG) sensor
EP3641634A4 (en) * 2017-06-20 2021-03-10 I.R Med Ltd SYSTEM AND METHOD OF NON-INVASIVE SUBCUTANEOUS TISSUE ANALYSIS
KR102408951B1 (ko) 2017-09-18 2022-06-13 삼성전자주식회사 글루코스 노출량 추정 장치 및 방법과, 글루코스 노출량 추정 모델 생성 장치 및 방법
KR20200097144A (ko) 2019-02-07 2020-08-18 삼성전자주식회사 생체정보 추정 장치 및 방법

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1909882B2 (de) 1969-02-27 1976-11-11 Arnold, Karl M., Dr., 8000 München; Beck, Harald, Prof., 6078 Neu-Isenburg Einrichtung zum messen von koerperfunktionen bei mensch und tier durch messung der optischen reflexionseigenschaften des wechselnd durchbluteten gewebes und verfahren zu ihrer herstellung
DE2424549A1 (de) 1973-05-23 1974-12-12 John Michael Prof Thompson Stroemungsmittelanalysiergeraet
DE2606991A1 (de) 1976-02-20 1977-08-25 Nils Dr Med Kaiser Geraet zur bestimmung des gehaltes von stoffwechselprodukten im blut
DE2934190A1 (de) 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
US4655225A (en) 1985-04-18 1987-04-07 Kurabo Industries Ltd. Spectrophotometric method and apparatus for the non-invasive
US4890619A (en) * 1986-04-15 1990-01-02 Hatschek Rudolf A System for the measurement of the content of a gas in blood, in particular the oxygen saturation of blood
AU1349388A (en) 1987-02-25 1988-09-26 Scientific Generics Limited In vivo blood testing
US5510894A (en) 1988-12-22 1996-04-23 Renishaw Plc Spectroscopic apparatus and methods
US5086229A (en) 1989-01-19 1992-02-04 Futrex, Inc. Non-invasive measurement of blood glucose
US5183042A (en) 1989-05-23 1993-02-02 Vivascan Corporation Electromagnetic method and apparatus to measure constituents of human or animal tissue
US4975581A (en) 1989-06-21 1990-12-04 University Of New Mexico Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
US5159929A (en) 1990-06-14 1992-11-03 Morris G Ronald Insulated rf shield
US5243983A (en) 1990-12-14 1993-09-14 Georgia Tech Research Corporation Non-invasive blood glucose measurement system and method using stimulated raman spectroscopy
US5261410A (en) 1991-02-07 1993-11-16 Alfano Robert R Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy
JPH06505183A (ja) 1991-02-26 1994-06-16 マサチユセツツ・インスチチユート・オブ・テクノロジー 組織を診断するための分子分光計のシステムおよび方法
US5194913A (en) 1991-03-20 1993-03-16 The United States Of America As Represented By The United States Department Of Energy Fiber-optic apparatus and method for measurement of luminescence and raman scattering
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
AU2245092A (en) * 1991-12-31 1993-07-28 Vivascan Corporation Blood constituent determination based on differential spectral analysis
US5370114A (en) 1992-03-12 1994-12-06 Wong; Jacob Y. Non-invasive blood chemistry measurement by stimulated infrared relaxation emission
IL107396A (en) 1992-11-09 1997-02-18 Boehringer Mannheim Gmbh Method and apparatus for analytical determination of glucose in a biological matrix
AU6186594A (en) 1993-05-07 1994-11-10 Diasense, Inc. Method for non-invasive measurement of concentration of analytes in blood
JPH0749309A (ja) 1993-08-05 1995-02-21 Kyoto Daiichi Kagaku:Kk 光散乱式成分濃度測定装置および方法
US5553616A (en) 1993-11-30 1996-09-10 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator
WO1997036540A1 (en) 1993-11-30 1997-10-09 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator
US5836317A (en) 1994-05-20 1998-11-17 Kunst; Hermann Transcutaneous non-bloody determination of the concentration of substances in the blood
US5553617A (en) 1995-01-20 1996-09-10 Hughes Aircraft Company Noninvasive method and apparatus for determining body chemistry
US5615673A (en) 1995-03-27 1997-04-01 Massachusetts Institute Of Technology Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
US5638816A (en) 1995-06-07 1997-06-17 Masimo Corporation Active pulse blood constituent monitoring
US5827181A (en) * 1995-09-07 1998-10-27 Hewlett-Packard Co. Noninvasive blood chemistry measurement method and system
DE19538372A1 (de) 1995-10-14 1997-04-17 Laser & Med Tech Gmbh Nicht invasive Glukosemessung
JP3592416B2 (ja) 1995-10-31 2004-11-24 晃敏 吉田 眼内物質の測定装置
US6232609B1 (en) 1995-12-01 2001-05-15 Cedars-Sinai Medical Center Glucose monitoring apparatus and method using laser-induced emission spectroscopy
WO1998003847A2 (en) 1996-07-19 1998-01-29 Mills Alexander K Device for noninvasive determination of blood parameters
KR101354333B1 (ko) 2012-02-24 2014-01-27 엘지디스플레이 주식회사 백라이트 디밍 방법과 이를 이용한 액정표시장치

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