ES2183522T3 - Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo. - Google Patents

Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo.

Info

Publication number
ES2183522T3
ES2183522T3 ES99910395T ES99910395T ES2183522T3 ES 2183522 T3 ES2183522 T3 ES 2183522T3 ES 99910395 T ES99910395 T ES 99910395T ES 99910395 T ES99910395 T ES 99910395T ES 2183522 T3 ES2183522 T3 ES 2183522T3
Authority
ES
Spain
Prior art keywords
lactitol
cristalino
crystalization
product
microcrystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99910395T
Other languages
English (en)
Inventor
Heikki Heikkila
Johanna Nygren
Marja-Leena Sarkki
H Kan Gros
Olli-Pekka Eroma
Julita Pearson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco Sweeteners Oy
Original Assignee
Danisco Sweeteners Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Sweeteners Oy filed Critical Danisco Sweeteners Oy
Application granted granted Critical
Publication of ES2183522T3 publication Critical patent/ES2183522T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Seasonings (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la cristalización de lactitol, que comprende: - establecer contacto de un líquido que contiene lactitol disuelto con finas partículas sólidas suspendidas en gas que contienen lactitol microcristalino; - provocar una eliminación sustancial del disolvente de dicho líquido y permitir que el lactitol resultante forme un compuesto esencialmente sólido de material que comprende una serie de microcristales de lactitol; y - provocar el acondicionamiento de dicha composición de lactitol durante una etapa adicional para proporcionar un producto que consiste esencialmente en la totalidad de su estructura en una serie de microcristales de lactitol aglomerado, unidos de forma al azar.
ES99910395T 1998-03-18 1999-03-17 Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo. Expired - Lifetime ES2183522T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI980600A FI107732B (fi) 1998-03-18 1998-03-18 Laktitolin kiteyttäminen, kiteinen laktitolituote ja sen käyttö

Publications (1)

Publication Number Publication Date
ES2183522T3 true ES2183522T3 (es) 2003-03-16

Family

ID=8551308

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99910395T Expired - Lifetime ES2183522T3 (es) 1998-03-18 1999-03-17 Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo.

Country Status (9)

Country Link
US (1) US6395893B1 (es)
EP (1) EP1064293B1 (es)
JP (1) JP2003525852A (es)
AT (1) ATE224906T1 (es)
AU (1) AU2936699A (es)
DE (1) DE69903141T2 (es)
ES (1) ES2183522T3 (es)
FI (1) FI107732B (es)
WO (1) WO1999047532A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19943496C1 (de) 1999-09-10 2001-05-17 Suedzucker Ag Direkt verpressbarer Rohstoff für Komprimate
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
FI20021312A (fi) 2002-07-03 2004-01-04 Danisco Sweeteners Oy Polyolikoostumusten kiteyttäminen, kiteinen polyolikoostumustuote ja sen käyttö
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
JP5800451B2 (ja) * 2005-04-08 2015-10-28 ピーティーシー セラピューティクス,インコーポレーテッド ナンセンス突然変異抑制治療用の、経口的に活性な1,2,4−オキサジアゾール組成物
CN1891299B (zh) * 2005-06-28 2012-06-27 上野制药株式会社 用于压片的糖醇组合物
EP2491788B1 (en) 2011-02-25 2015-12-23 Kraft Foods R & D, Inc. Food product with a moulded body
US10806743B1 (en) 2017-05-12 2020-10-20 Braintree Laboratories, Inc. Method of administering lactitol to reduce plasma concentration of lactitol

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8002823A (nl) * 1980-05-14 1981-12-16 Amsterdam Chem Comb Lactitolmonohydraat, alsmede werkwijze voor het bereiden van kristallijn lactitol.
JPS5885900A (ja) * 1981-11-17 1983-05-23 セ−セ−ア−・ビオヘム・ベ−・ヴェ− ラクチトール水和物結晶の製造方法
JPH0710343B2 (ja) 1985-12-26 1995-02-08 株式会社林原生物化学研究所 無水ラクチト−ルによる含水物の脱水方法
DD252003B1 (de) * 1986-08-01 1990-06-20 Hydrierwerk Rodleben Veb Verfahren zur herstellung eines trockensorbitols mit verbesserten anwendungstechnischen eigenschaften
JPS6434261A (en) * 1987-04-09 1989-02-03 Takeda Chemical Industries Ltd Production of sweetener
JPH01206969A (ja) * 1987-10-30 1989-08-21 Takeda Chem Ind Ltd 甘味料顆粒の製造法
FI83965C (fi) 1988-12-01 1991-09-25 Suomen Sokeri Oy Kristallint laktitolmonohydrat och foerfarande foer dess framstaellning samt dess anvaendning.
JPH02196794A (ja) * 1989-01-24 1990-08-03 Towa Kasei Kogyo Kk 新規なラクチトール一水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法
JPH075624B2 (ja) 1989-01-31 1995-01-25 東和化成工業株式会社 ラクチトール三水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法
JP3060385B2 (ja) * 1989-01-31 2000-07-10 東和化成工業株式会社 新規なラクチトール無水物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法
JPH02222663A (ja) * 1989-02-27 1990-09-05 Ajinomoto Co Inc ラクチトール含有顆粒の製造法
JP3000283B2 (ja) * 1989-03-29 2000-01-17 東和化成工業株式会社 ラクチトール無水物結晶を含有する含密結晶の製造方法及び含密結晶組成物の製造方法
FI91261C (fi) * 1991-03-22 1996-01-31 Xyrofin Oy Kiteinen, kidevedetön laktitoli ja menetelmä sen valmistamiseksi sekä sen käyttö
FR2705207B1 (fr) 1993-05-17 1995-07-28 Roquette Freres Procédé de dragéification dure sans sucre et produits ainsi obtenus.
FR2728436A1 (fr) * 1994-12-26 1996-06-28 Roquette Freres Sucre cuit et son procede de fabrication
US5651988A (en) * 1995-08-18 1997-07-29 Xyrofin Oy Combination osmotic and bulk forming laxatives
JP4090529B2 (ja) * 1996-01-24 2008-05-28 フロイント産業株式会社 乳糖の球形粒及びその製造方法
JPH09216816A (ja) * 1996-02-08 1997-08-19 Nippon Shinyaku Co Ltd 高水溶性固形医薬用速溶錠
DE19615418A1 (de) 1996-04-22 1997-10-23 Merck Patent Gmbh Polyol-Zusammensetzung
US5846568A (en) 1996-09-19 1998-12-08 Xyrofin Oy Directly compressible lactitol and method
FR2753972B1 (fr) 1996-09-27 1998-12-04 Roquette Freres Composition de lactitol et son procede de preparation

Also Published As

Publication number Publication date
FI980600A0 (fi) 1998-03-18
WO1999047532A1 (en) 1999-09-23
AU2936699A (en) 1999-10-11
FI980600A (fi) 1999-09-19
FI107732B (fi) 2001-09-28
ATE224906T1 (de) 2002-10-15
DE69903141D1 (de) 2002-10-31
JP2003525852A (ja) 2003-09-02
EP1064293A1 (en) 2001-01-03
US6395893B1 (en) 2002-05-28
EP1064293B1 (en) 2002-09-25
DE69903141T2 (de) 2003-05-28

Similar Documents

Publication Publication Date Title
ES2168290T3 (es) Metodo para preparar una composicion de liberacion sostenida.
ES2134501T5 (es) Composicion farmaceutica conteniendo un soporte fundible y procedimiento para su fabricacion.
ES2520841T3 (es) Procedimiento para la producción de partículas
MA26562A1 (fr) Composes therapeutiquement actifs bases sur le remplacement bio-isosterique du catechol par l'indazole dans des inhibiteurs de pde4, leur procede de production et composition pharmaceutique les contenant.
ATE336589T1 (de) Deesterifizierte pectine, verfahren zur herstellung von diesen, und diese enthaltende stabilisierte saure flüssigkeitssysteme
DE3382587D1 (de) Injizierbares langwirkendes mikroteilchen-praeparat zur verabreichung entzuendungshemmender mittel.
AR012820A1 (es) Un proceso para la preparacion de microparticulas biodegradables y biocompatibles
BR0304937B1 (pt) composição de antiespumante de silicone encapsulado e processo para a produção de uma composição de antiespumante de silicone encapsulado.
ES2183522T3 (es) Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo.
CA2335270A1 (en) Electrochromic media with concentration-enhanced stability, process for the preparation thereof and use in electrochromic devices
BR0115346A (pt) Compostos intermetálicos
KR950031092A (ko) 스토마-주변 염증 질환 치료용 약제학적 조성물
BR9913720A (pt) Processo de purificação por cristalização ourecristalização de ácidos carboxìlicos
TW200736261A (en) Method of purifying episesamin
ES2186236T3 (es) Meetodos para producir subconjuntos solidos de material en particulas fluidificado para intercambio de iones.
BR0013562A (pt) Processo para a fabricação de grãos contendo uma substância ativa, grãos porosos de rápida desintegração e utilização dos grãos
RU96103974A (ru) Способ выделения синтетических ультрадисперсных алмазов
JP2002540257A5 (es)
AR000393A1 (es) Procedimiento para la preparación de un producto que contiene isobutano/isohexano
AU5985599A (en) Process for grinding noble metals in liquid medium
AU2001284476A1 (en) Novel crystals of 1,3,4-oxadiazole derivative, process for producing the crystals and medicines containing the same as the active ingredient
AU1138697A (en) A method for preparing a non-fibrous porous material
CO6160259A2 (es) Procesamiento de fundido de insecticidas fosforoamido (di) tioato
DE60103866D1 (de) Konfektionierung von neopentylglykol
Vajda et al. Freezing Effect on Chirality Amplification of L-Asparagine by Crystallization of the Racemate in Preferential Condition