ES2183522T3 - Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo. - Google Patents
Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo.Info
- Publication number
- ES2183522T3 ES2183522T3 ES99910395T ES99910395T ES2183522T3 ES 2183522 T3 ES2183522 T3 ES 2183522T3 ES 99910395 T ES99910395 T ES 99910395T ES 99910395 T ES99910395 T ES 99910395T ES 2183522 T3 ES2183522 T3 ES 2183522T3
- Authority
- ES
- Spain
- Prior art keywords
- lactitol
- cristalino
- crystalization
- product
- microcrystals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Seasonings (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la cristalización de lactitol, que comprende: - establecer contacto de un líquido que contiene lactitol disuelto con finas partículas sólidas suspendidas en gas que contienen lactitol microcristalino; - provocar una eliminación sustancial del disolvente de dicho líquido y permitir que el lactitol resultante forme un compuesto esencialmente sólido de material que comprende una serie de microcristales de lactitol; y - provocar el acondicionamiento de dicha composición de lactitol durante una etapa adicional para proporcionar un producto que consiste esencialmente en la totalidad de su estructura en una serie de microcristales de lactitol aglomerado, unidos de forma al azar.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI980600A FI107732B (fi) | 1998-03-18 | 1998-03-18 | Laktitolin kiteyttäminen, kiteinen laktitolituote ja sen käyttö |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2183522T3 true ES2183522T3 (es) | 2003-03-16 |
Family
ID=8551308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99910395T Expired - Lifetime ES2183522T3 (es) | 1998-03-18 | 1999-03-17 | Cristalizacion de lactitol, producto de lactitol cristalino y utilizacion del mismo. |
Country Status (9)
Country | Link |
---|---|
US (1) | US6395893B1 (es) |
EP (1) | EP1064293B1 (es) |
JP (1) | JP2003525852A (es) |
AT (1) | ATE224906T1 (es) |
AU (1) | AU2936699A (es) |
DE (1) | DE69903141T2 (es) |
ES (1) | ES2183522T3 (es) |
FI (1) | FI107732B (es) |
WO (1) | WO1999047532A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19943496C1 (de) | 1999-09-10 | 2001-05-17 | Suedzucker Ag | Direkt verpressbarer Rohstoff für Komprimate |
US7118765B2 (en) * | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
FI20021312A (fi) | 2002-07-03 | 2004-01-04 | Danisco Sweeteners Oy | Polyolikoostumusten kiteyttäminen, kiteinen polyolikoostumustuote ja sen käyttö |
US20070059358A1 (en) * | 2003-07-02 | 2007-03-15 | Tianjin Tasly Pharmaceutical Co., Ltd., China | Matrix adjuvants and the drop pills prepared with them |
JP5800451B2 (ja) * | 2005-04-08 | 2015-10-28 | ピーティーシー セラピューティクス,インコーポレーテッド | ナンセンス突然変異抑制治療用の、経口的に活性な1,2,4−オキサジアゾール組成物 |
CN1891299B (zh) * | 2005-06-28 | 2012-06-27 | 上野制药株式会社 | 用于压片的糖醇组合物 |
EP2491788B1 (en) | 2011-02-25 | 2015-12-23 | Kraft Foods R & D, Inc. | Food product with a moulded body |
US10806743B1 (en) | 2017-05-12 | 2020-10-20 | Braintree Laboratories, Inc. | Method of administering lactitol to reduce plasma concentration of lactitol |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8002823A (nl) * | 1980-05-14 | 1981-12-16 | Amsterdam Chem Comb | Lactitolmonohydraat, alsmede werkwijze voor het bereiden van kristallijn lactitol. |
JPS5885900A (ja) * | 1981-11-17 | 1983-05-23 | セ−セ−ア−・ビオヘム・ベ−・ヴェ− | ラクチトール水和物結晶の製造方法 |
JPH0710343B2 (ja) | 1985-12-26 | 1995-02-08 | 株式会社林原生物化学研究所 | 無水ラクチト−ルによる含水物の脱水方法 |
DD252003B1 (de) * | 1986-08-01 | 1990-06-20 | Hydrierwerk Rodleben Veb | Verfahren zur herstellung eines trockensorbitols mit verbesserten anwendungstechnischen eigenschaften |
JPS6434261A (en) * | 1987-04-09 | 1989-02-03 | Takeda Chemical Industries Ltd | Production of sweetener |
JPH01206969A (ja) * | 1987-10-30 | 1989-08-21 | Takeda Chem Ind Ltd | 甘味料顆粒の製造法 |
FI83965C (fi) | 1988-12-01 | 1991-09-25 | Suomen Sokeri Oy | Kristallint laktitolmonohydrat och foerfarande foer dess framstaellning samt dess anvaendning. |
JPH02196794A (ja) * | 1989-01-24 | 1990-08-03 | Towa Kasei Kogyo Kk | 新規なラクチトール一水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法 |
JPH075624B2 (ja) | 1989-01-31 | 1995-01-25 | 東和化成工業株式会社 | ラクチトール三水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法 |
JP3060385B2 (ja) * | 1989-01-31 | 2000-07-10 | 東和化成工業株式会社 | 新規なラクチトール無水物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法 |
JPH02222663A (ja) * | 1989-02-27 | 1990-09-05 | Ajinomoto Co Inc | ラクチトール含有顆粒の製造法 |
JP3000283B2 (ja) * | 1989-03-29 | 2000-01-17 | 東和化成工業株式会社 | ラクチトール無水物結晶を含有する含密結晶の製造方法及び含密結晶組成物の製造方法 |
FI91261C (fi) * | 1991-03-22 | 1996-01-31 | Xyrofin Oy | Kiteinen, kidevedetön laktitoli ja menetelmä sen valmistamiseksi sekä sen käyttö |
FR2705207B1 (fr) | 1993-05-17 | 1995-07-28 | Roquette Freres | Procédé de dragéification dure sans sucre et produits ainsi obtenus. |
FR2728436A1 (fr) * | 1994-12-26 | 1996-06-28 | Roquette Freres | Sucre cuit et son procede de fabrication |
US5651988A (en) * | 1995-08-18 | 1997-07-29 | Xyrofin Oy | Combination osmotic and bulk forming laxatives |
JP4090529B2 (ja) * | 1996-01-24 | 2008-05-28 | フロイント産業株式会社 | 乳糖の球形粒及びその製造方法 |
JPH09216816A (ja) * | 1996-02-08 | 1997-08-19 | Nippon Shinyaku Co Ltd | 高水溶性固形医薬用速溶錠 |
DE19615418A1 (de) | 1996-04-22 | 1997-10-23 | Merck Patent Gmbh | Polyol-Zusammensetzung |
US5846568A (en) | 1996-09-19 | 1998-12-08 | Xyrofin Oy | Directly compressible lactitol and method |
FR2753972B1 (fr) | 1996-09-27 | 1998-12-04 | Roquette Freres | Composition de lactitol et son procede de preparation |
-
1998
- 1998-03-18 FI FI980600A patent/FI107732B/fi not_active IP Right Cessation
-
1999
- 1999-03-17 JP JP2000536727A patent/JP2003525852A/ja active Pending
- 1999-03-17 AU AU29366/99A patent/AU2936699A/en not_active Abandoned
- 1999-03-17 AT AT99910395T patent/ATE224906T1/de not_active IP Right Cessation
- 1999-03-17 US US09/646,411 patent/US6395893B1/en not_active Expired - Lifetime
- 1999-03-17 DE DE69903141T patent/DE69903141T2/de not_active Expired - Lifetime
- 1999-03-17 WO PCT/FI1999/000206 patent/WO1999047532A1/en active IP Right Grant
- 1999-03-17 ES ES99910395T patent/ES2183522T3/es not_active Expired - Lifetime
- 1999-03-17 EP EP99910395A patent/EP1064293B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI980600A0 (fi) | 1998-03-18 |
WO1999047532A1 (en) | 1999-09-23 |
AU2936699A (en) | 1999-10-11 |
FI980600A (fi) | 1999-09-19 |
FI107732B (fi) | 2001-09-28 |
ATE224906T1 (de) | 2002-10-15 |
DE69903141D1 (de) | 2002-10-31 |
JP2003525852A (ja) | 2003-09-02 |
EP1064293A1 (en) | 2001-01-03 |
US6395893B1 (en) | 2002-05-28 |
EP1064293B1 (en) | 2002-09-25 |
DE69903141T2 (de) | 2003-05-28 |
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