ES2177246T3 - Formulacion farmaceutica que comprende un 2-((2-piridinil)metil)sulfinil)benzimidazol dotado de actividad antiulcerosa y procedimiento de preparacion de dicha formulacion. - Google Patents
Formulacion farmaceutica que comprende un 2-((2-piridinil)metil)sulfinil)benzimidazol dotado de actividad antiulcerosa y procedimiento de preparacion de dicha formulacion.Info
- Publication number
- ES2177246T3 ES2177246T3 ES99907346T ES99907346T ES2177246T3 ES 2177246 T3 ES2177246 T3 ES 2177246T3 ES 99907346 T ES99907346 T ES 99907346T ES 99907346 T ES99907346 T ES 99907346T ES 2177246 T3 ES2177246 T3 ES 2177246T3
- Authority
- ES
- Spain
- Prior art keywords
- formulation
- methyl
- coating
- coating layer
- benzimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Formulación farmacéutica oral que comprende 2-[[(2- piridinil)metil]sulfinil] benzimidazol como principio activo, que posee actividad antiulcerosa, comprendiendo dicha formulación gránulos que tienen una parte central sustancialmente inerte recubierta con: I) una capa interna de recubrimiento que comprende el benzimidazol, un disgregador y un tensioactivo en una matriz de una sustancia de recubrimiento fundida consistente esencialmente en uno o más ésteres de glicerol y ácidos grasos, II) una capa externa de recubrimiento que es un recubrimiento entérico, y III) una capa intermedia de recubrimiento que separa la capa de recubrimiento entérico de la capa interna de recubrimiento para la protección del benzimidazol contra la degradación por los ingredientes del recubrimiento entérico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK199800397A DK173431B1 (da) | 1998-03-20 | 1998-03-20 | Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2177246T3 true ES2177246T3 (es) | 2002-12-01 |
Family
ID=8093069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99907346T Expired - Lifetime ES2177246T3 (es) | 1998-03-20 | 1999-03-17 | Formulacion farmaceutica que comprende un 2-((2-piridinil)metil)sulfinil)benzimidazol dotado de actividad antiulcerosa y procedimiento de preparacion de dicha formulacion. |
Country Status (20)
Country | Link |
---|---|
US (1) | US6391342B1 (es) |
EP (1) | EP1061920B1 (es) |
AR (1) | AR014753A1 (es) |
AT (1) | ATE218863T1 (es) |
AU (1) | AU744596B2 (es) |
CA (1) | CA2323536C (es) |
CZ (1) | CZ291943B6 (es) |
DE (1) | DE69901804T2 (es) |
DK (2) | DK173431B1 (es) |
EA (1) | EA002502B1 (es) |
ES (1) | ES2177246T3 (es) |
HU (1) | HU226580B1 (es) |
IS (1) | IS2265B (es) |
NO (1) | NO20004667L (es) |
NZ (1) | NZ507115A (es) |
PL (1) | PL192437B1 (es) |
TR (1) | TR200002696T2 (es) |
TW (1) | TW529951B (es) |
WO (1) | WO1999048498A1 (es) |
ZA (1) | ZA200004757B (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020039597A1 (en) | 1998-04-20 | 2002-04-04 | Koji Ukai | Stabilized compositions containing benzimidazole-type compounds |
ZA9810765B (en) * | 1998-05-28 | 1999-08-06 | Ranbaxy Lab Ltd | Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole. |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
ATE300285T1 (de) | 1999-06-07 | 2005-08-15 | Altana Pharma Ag | Neue zubereitung und darreichungsform enthaltend einen säurelabilen protonenpumpeninhibitor |
EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
ES2168043B1 (es) | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
AR021347A1 (es) | 1999-10-20 | 2002-07-17 | Cipla Ltd | Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma |
WO2001032185A1 (en) * | 1999-11-02 | 2001-05-10 | Cipla Ltd. | A pharmaceutical composition containing bisphosphonic acid(s) or salt(s) thereof and a process of preparing thereof |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20060034937A1 (en) * | 1999-11-23 | 2006-02-16 | Mahesh Patel | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
DE19959419A1 (de) | 1999-12-09 | 2001-06-21 | Ratiopharm Gmbh | Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung |
ES2191521B1 (es) * | 2000-11-22 | 2005-02-16 | Laboratorios Belmac, S.A. | Nueva formulacion galenica del omeprazol en forma de comprimidos, procedimiento para su preparacion y aplicaciones en medicina humana y en veterinaria. |
MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
WO2004089333A2 (en) * | 2003-02-28 | 2004-10-21 | Cadila Healthcare Limited | A stable benzimidazole formulation |
ES2234393B2 (es) * | 2003-04-29 | 2006-09-01 | Laboratorios Belmac, S.A. | "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido". |
TWI372066B (en) | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
BRPI0415242B8 (pt) * | 2003-10-10 | 2021-05-25 | Ethypharm Sa | microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes |
EP1699458A4 (en) * | 2003-12-30 | 2012-04-25 | Reddys Lab Ltd Dr | PHARMACEUTICAL COMPOSITION |
US20050181052A1 (en) * | 2004-02-17 | 2005-08-18 | Patel Satishkumar A. | Lansoprazole microtablets |
US20050214371A1 (en) * | 2004-03-03 | 2005-09-29 | Simona Di Capua | Stable pharmaceutical composition comprising an acid labile drug |
RS52233B (en) | 2004-05-07 | 2012-10-31 | Nycomed Gmbh | THE PHARMACEUTICAL DOSAGE FORM CONTAINING GRANULES AND ITS PRODUCTION PROCEDURE |
EP1768668A2 (en) * | 2004-06-16 | 2007-04-04 | Tap Pharmaceutical Products, Inc. | Multiple ppi dosage form |
CA2633254A1 (en) * | 2005-12-16 | 2007-07-05 | Tap Pharmaceutical Products, Inc. | Pharmaceutical compositions of ilaprazole |
WO2007100984A2 (en) * | 2006-02-24 | 2007-09-07 | Allergan, Inc. | Beads containing pyridin-sulfinyl benzoimidazole sulfonyl phenoxy acetate derivatives |
US20100297226A1 (en) * | 2006-06-01 | 2010-11-25 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
US8486452B2 (en) | 2007-07-20 | 2013-07-16 | Mylan Pharmaceuticals Inc. | Stabilized tolterodine tartrate formulations |
US8110226B2 (en) * | 2007-07-20 | 2012-02-07 | Mylan Pharmaceuticals Inc. | Drug formulations having inert sealed cores |
US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
US20100239681A1 (en) * | 2009-03-20 | 2010-09-23 | Biokey, Inc. | Controlled Release Particulates Containing Water-Insoluble Drug |
WO2010122583A2 (en) | 2009-04-24 | 2010-10-28 | Rubicon Research Private Limited | Oral pharmaceutical compositions of acid labile substances |
EP2319504A1 (en) * | 2009-11-07 | 2011-05-11 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical solid dosage form |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
CN103202820B (zh) * | 2012-01-11 | 2016-03-30 | 浙江亚太药业股份有限公司 | 一种稳定的兰索拉唑肠溶胶囊及其制备方法 |
WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
WO2016033549A2 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CA3078723A1 (en) | 2016-11-28 | 2018-05-31 | Nachiappan Chidambaram | Oral testosterone undecanoate therapy |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
CA1327010C (en) | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
GB2189698A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
GB2189699A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
US5026560A (en) | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
ES2024993A6 (es) | 1990-12-31 | 1992-03-01 | Genesis Para La Investigacion | Procedimiento de obtencion de un preparado farmaceutico oral conteniendo omeprazol. |
TW209174B (es) | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
YU48263B (sh) | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
ATE156707T1 (de) * | 1991-06-21 | 1997-08-15 | Ilsan Ilac Ve Hammaddeleri San | Neues galenisches verfahren für omeprazol enthaltende pellets |
SE9200858L (sv) | 1992-03-20 | 1993-09-21 | Kabi Pharmacia Ab | Metod för framställning av pellets med fördröjd frisättning |
FR2692146B1 (fr) | 1992-06-16 | 1995-06-02 | Ethypharm Sa | Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention. |
AU4513393A (en) | 1992-07-17 | 1994-02-14 | Astra Aktiebolag | Pharmaceutical composition containing antiulcer agent |
ES2087823B1 (es) | 1994-07-13 | 1997-02-16 | Estudes Et Richerches Pharma E | Formulacion de microgranulos gastroresistentes de omeprazol y su procedimiento de fabricacion. |
ES2094694B1 (es) | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion. |
SE9500478D0 (sv) | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
CH687810A5 (de) | 1995-05-24 | 1997-02-28 | Mepha Ag | Pelletformulierung mit Omeprazol. |
DK0859612T3 (da) | 1995-09-21 | 2003-09-22 | Pharma Pass Ii Llc | Farmaceutisk sammensætning indeholdende en syre-labil omeprazol og fremgangsmåde til fremstilling deraf |
SE9600072D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
PT101826A (pt) | 1996-02-06 | 1997-09-30 | Medinfar Produtos Farmaceutico | Processo para a preparacao de microgranulos contendo omeprazole |
EP0968204A1 (en) | 1997-03-07 | 2000-01-05 | A/S GEA Farmaceutisk Fabrik | Process for the preparation of 2- (2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose |
-
1998
- 1998-03-20 DK DK199800397A patent/DK173431B1/da not_active IP Right Cessation
-
1999
- 1999-03-12 TW TW088103837A patent/TW529951B/zh active
- 1999-03-17 HU HU0101178A patent/HU226580B1/hu not_active IP Right Cessation
- 1999-03-17 CZ CZ20003458A patent/CZ291943B6/cs not_active IP Right Cessation
- 1999-03-17 AU AU27148/99A patent/AU744596B2/en not_active Ceased
- 1999-03-17 EA EA200000970A patent/EA002502B1/ru not_active IP Right Cessation
- 1999-03-17 EP EP99907346A patent/EP1061920B1/en not_active Expired - Lifetime
- 1999-03-17 PL PL342840A patent/PL192437B1/pl not_active IP Right Cessation
- 1999-03-17 US US09/646,486 patent/US6391342B1/en not_active Expired - Fee Related
- 1999-03-17 ES ES99907346T patent/ES2177246T3/es not_active Expired - Lifetime
- 1999-03-17 TR TR2000/02696T patent/TR200002696T2/xx unknown
- 1999-03-17 AT AT99907346T patent/ATE218863T1/de not_active IP Right Cessation
- 1999-03-17 DK DK99907346T patent/DK1061920T3/da active
- 1999-03-17 NZ NZ507115A patent/NZ507115A/xx unknown
- 1999-03-17 WO PCT/DK1999/000137 patent/WO1999048498A1/en active IP Right Grant
- 1999-03-17 DE DE69901804T patent/DE69901804T2/de not_active Expired - Fee Related
- 1999-03-17 CA CA002323536A patent/CA2323536C/en not_active Expired - Fee Related
- 1999-03-19 AR ARP990101230A patent/AR014753A1/es not_active Application Discontinuation
-
2000
- 2000-09-08 ZA ZA200004757A patent/ZA200004757B/xx unknown
- 2000-09-13 IS IS5628A patent/IS2265B/is unknown
- 2000-09-19 NO NO20004667A patent/NO20004667L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ20003458A3 (cs) | 2001-03-14 |
TR200002696T2 (tr) | 2000-12-21 |
TW529951B (en) | 2003-05-01 |
DE69901804T2 (de) | 2002-12-12 |
AR014753A1 (es) | 2001-03-28 |
AU744596B2 (en) | 2002-02-28 |
EP1061920A1 (en) | 2000-12-27 |
NZ507115A (en) | 2002-09-27 |
US6391342B1 (en) | 2002-05-21 |
DK1061920T3 (da) | 2002-07-15 |
PL192437B1 (pl) | 2006-10-31 |
EA200000970A1 (ru) | 2001-02-26 |
DE69901804D1 (de) | 2002-07-18 |
DK173431B1 (da) | 2000-10-23 |
EA002502B1 (ru) | 2002-06-27 |
ZA200004757B (en) | 2001-05-30 |
AU2714899A (en) | 1999-10-18 |
PL342840A1 (en) | 2001-07-16 |
NO20004667D0 (no) | 2000-09-19 |
CA2323536A1 (en) | 1999-09-30 |
CZ291943B6 (cs) | 2003-06-18 |
EP1061920B1 (en) | 2002-06-12 |
CA2323536C (en) | 2009-05-19 |
HUP0101178A2 (hu) | 2001-08-28 |
HU226580B1 (en) | 2009-04-28 |
NO20004667L (no) | 2000-11-09 |
IS2265B (is) | 2007-07-15 |
ATE218863T1 (de) | 2002-06-15 |
IS5628A (is) | 2000-09-13 |
DK39798A (da) | 1999-09-21 |
WO1999048498A1 (en) | 1999-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2177246T3 (es) | Formulacion farmaceutica que comprende un 2-((2-piridinil)metil)sulfinil)benzimidazol dotado de actividad antiulcerosa y procedimiento de preparacion de dicha formulacion. | |
EP1051174B1 (fr) | Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques | |
KR100755154B1 (ko) | 경구용 제약학적 서방형 투여 제형 | |
AR030920A1 (es) | Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones | |
ES2194732T3 (es) | Composiciones farmaceuticas orales de liberacion controlada de mesalazina. | |
CL2007002000A1 (es) | Preparacion farmaceutica para la administracion oral con liberacion controlada de ingrediente activo en el intestino delgado que comprende portadores inertes, ingredientes activo, una capa interna compuesta de 2 capas de difusion para controlar la liberacion y una capa gastrorresistente; metodo de preparacion. | |
ES2167891T3 (es) | Estabilizacion de bencimidazoles sensibles a los acidos con combinaciones amino/ciclodextrina. | |
DE60217880T2 (de) | Pflaster mit sertaconazol zur behandlung von nagelfunktionsstörungen und erkrankungen | |
AR100473A2 (es) | Un método para la manufactura de una preparación para administración oral | |
DK1086694T3 (da) | Oral farmaceutisk formulering i fast form med modificeret frigivelse, der indeholder en syrelabil benzimidazolforbindelse | |
BRPI0614417A2 (pt) | composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas | |
SE8004938L (sv) | Farmaceutisk kompositon av fast lekemedel med fordrojd frigoring | |
NZ596657A (en) | Self micro-emulsifying oral pharmaceutical composition of hydrophilic drug and preparation method thereof | |
WO2001022791A3 (en) | Controlled release compositions comprising nimesulide | |
KR20090086078A (ko) | 항부정맥제 및 오메가-3 지방산 및 이들의 조합 생성물로의 치료 | |
RS53201B (en) | BENDAMUSTIN ORAL DOSAGE FORMS | |
AR076305A1 (es) | Composiciones de capsulas biodisponibles de compuesto alfa-(n-sulfonamido) acetamida amorfo | |
UY26303A1 (es) | Composiciones farmacéuticas para administración oral y tópica | |
EP1178799B1 (fr) | Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques | |
PE20080313A1 (es) | Formulaciones de liberacion pulsada de fenilefrina y composiciones farmaceuticas | |
Devine et al. | Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole | |
PE20050335A1 (es) | Forma de dosificacion oral que comprende 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona y procedimiento para la preparacion | |
Ortiz et al. | Oxfendazole flukicidal activity in pigs | |
EE05231B1 (et) | Tramadoolvesinikkloriidi sisaldav toimeainet reguleeritult vabastav ravimkoostis ja meetod selle valmistamiseks | |
TR200200683T2 (tr) | Oral kontrollü salıverme formülasyonları. |