ES2176201T3 - Derivados de 4-difenilmetil piperidina y procedimiento de preparacion. - Google Patents
Derivados de 4-difenilmetil piperidina y procedimiento de preparacion.Info
- Publication number
- ES2176201T3 ES2176201T3 ES93907333T ES93907333T ES2176201T3 ES 2176201 T3 ES2176201 T3 ES 2176201T3 ES 93907333 T ES93907333 T ES 93907333T ES 93907333 T ES93907333 T ES 93907333T ES 2176201 T3 ES2176201 T3 ES 2176201T3
- Authority
- ES
- Spain
- Prior art keywords
- piperidine
- derivatives
- difenylmetil
- preparation procedure
- ch2oh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Abstract
LA PRESENTE INVENCION ES RELATIVA A UN NUEVO PROCESO PARA PREPARAR CIERTOS DERIVADOS DE PIPERIDINA DE FORMULA (I) Y (II) EN DONDE R1 REPRESENTA HIDROGENO O HIDROXI, R2 REPRESENTA HIDROGENO; O R1 Y R2 TOMADOS JUNTOS FORMAN UN SEGUNDO ENLACE ENTRE LOS ATOMOS DE CARBONO QUE SOPORTAN R1 Y R2; N ES UN ENTERO DE DESDE 1 A 5; R3 ES -CH2OH, -CH2OH, -COOH O -COOALQUILO EN DONDE EL ALQUILO CENTRAL TIENE DE 1 A 6 ATOMOS DE CARBONO Y ES LINEAL O RAMIFICADO; CADA A ES HIDROGENO O HIDROXI. Y SALES FARMACEUTICAMENTE ACEPTABLES E ISOMEROS OPTICOS INDIVIDUALES DE ELLOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86726192A | 1992-04-10 | 1992-04-10 | |
US1725193A | 1993-02-25 | 1993-02-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2176201T3 true ES2176201T3 (es) | 2002-12-01 |
Family
ID=26689638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93907333T Expired - Lifetime ES2176201T3 (es) | 1992-04-10 | 1993-03-10 | Derivados de 4-difenilmetil piperidina y procedimiento de preparacion. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0635004B1 (es) |
JP (3) | JP3686950B2 (es) |
KR (1) | KR100257805B1 (es) |
AR (1) | AR253777A1 (es) |
AT (1) | ATE220666T1 (es) |
AU (1) | AU671822B2 (es) |
CA (1) | CA2117892C (es) |
DE (1) | DE69332117T2 (es) |
DK (1) | DK0635004T3 (es) |
ES (1) | ES2176201T3 (es) |
FI (2) | FI106454B (es) |
HU (1) | HU226561B1 (es) |
IL (1) | IL105328A (es) |
MX (1) | MX9302076A (es) |
NO (5) | NO305076B1 (es) |
NZ (1) | NZ251132A (es) |
PT (1) | PT635004E (es) |
TW (1) | TW362096B (es) |
WO (1) | WO1993021156A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU226242B1 (en) * | 1992-08-03 | 2008-07-28 | Sepracor Inc | Use of terfenadin carboxylic acid, their salt and optically pure isomers for the preparation of pharmaceutical compositions, and pharmaceutical compositions against allergic disorders |
US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
DE69433346T2 (de) * | 1993-06-24 | 2004-09-09 | Albany Molecular Research, Inc. | Herstellung von Verbindungen, die in der Produktion von Piperidin-Derivaten nützlich sind |
AU699559B2 (en) | 1993-06-25 | 1998-12-10 | Aventisub Ii Inc. | Novel intermediates for the preparation of antihistaminic piperidine derivatives |
US6147216A (en) * | 1993-06-25 | 2000-11-14 | Merrell Pharmaceuticals Inc. | Intermediates useful for the preparation of antihistaminic piperidine derivatives |
CA2189007C (en) * | 1994-05-18 | 2004-03-02 | Daniel R. Henton | Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof |
ATE226819T1 (de) | 1995-02-28 | 2002-11-15 | Aventis Pharma Inc | Arzneizubereitungen für piperidinalkanolderivate |
US6201124B1 (en) | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
US6153754A (en) | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
BR9911794A (pt) * | 1998-07-02 | 2001-03-27 | Aventis Pharma Inc | Derivados anti-histamìnicos de piperidina e intermediários para a preparação dos mesmos |
PL366576A1 (en) * | 2001-04-09 | 2005-02-07 | Teva Pharmaceutical Industries Ltd. | Polymorphs of fexofenadine hydrochloride |
ITRM20010260A1 (it) | 2001-05-17 | 2002-11-18 | Dinamite Dipharma S P A In For | Processo per la preparazione della fexofenadina o acido 4 1-idrossi-4-4- (idrossidifenilmetil)-1-piperidinil|-butil|-alfa,alfa-dimetilbenz |
US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
EP1474392A1 (en) | 2002-06-10 | 2004-11-10 | Teva Pharmaceutical Industries Ltd. | Polymorphic form xvi of fexofenadine hydrochloride |
GB0319935D0 (en) * | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
ITMI20061492A1 (it) * | 2006-07-27 | 2008-01-28 | Archimica Srl | Processo per la preparazione di fexofenadina. |
ITMI20070987A1 (it) | 2007-05-16 | 2008-11-17 | Dipharma Francis Srl | Procedimento per la preparazione di composti chetonici |
EP2289867A3 (en) | 2009-08-19 | 2012-04-25 | Jubilant Organosys Limited | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US4254130A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
-
1993
- 1993-03-10 HU HU9402913A patent/HU226561B1/hu unknown
- 1993-03-10 NZ NZ251132A patent/NZ251132A/en not_active IP Right Cessation
- 1993-03-10 WO PCT/US1993/002103 patent/WO1993021156A1/en active IP Right Grant
- 1993-03-10 KR KR1019940703575A patent/KR100257805B1/ko not_active IP Right Cessation
- 1993-03-10 AU AU37973/93A patent/AU671822B2/en not_active Expired
- 1993-03-10 DK DK93907333T patent/DK0635004T3/da active
- 1993-03-10 JP JP51831393A patent/JP3686950B2/ja not_active Expired - Lifetime
- 1993-03-10 AT AT93907333T patent/ATE220666T1/de active
- 1993-03-10 EP EP93907333A patent/EP0635004B1/en not_active Expired - Lifetime
- 1993-03-10 CA CA002117892A patent/CA2117892C/en not_active Expired - Lifetime
- 1993-03-10 ES ES93907333T patent/ES2176201T3/es not_active Expired - Lifetime
- 1993-03-10 MX MX9302076A patent/MX9302076A/es unknown
- 1993-03-10 PT PT93907333T patent/PT635004E/pt unknown
- 1993-03-10 DE DE69332117T patent/DE69332117T2/de not_active Expired - Lifetime
- 1993-04-07 IL IL105328A patent/IL105328A/en not_active IP Right Cessation
- 1993-04-07 TW TW082102558A patent/TW362096B/zh not_active IP Right Cessation
- 1993-04-07 AR AR25377793A patent/AR253777A1/es unknown
-
1994
- 1994-10-07 FI FI944713A patent/FI106454B/fi not_active IP Right Cessation
- 1994-10-07 NO NO943794A patent/NO305076B1/no not_active IP Right Cessation
-
1998
- 1998-03-30 NO NO981433A patent/NO305024B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981432A patent/NO305077B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981434A patent/NO305025B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981431A patent/NO305023B1/no not_active IP Right Cessation
-
2000
- 2000-11-09 FI FI20002460A patent/FI20002460A/fi unknown
-
2004
- 2004-05-06 JP JP2004137675A patent/JP4266184B2/ja not_active Expired - Lifetime
-
2005
- 2005-04-01 JP JP2005105603A patent/JP2005213268A/ja active Pending
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