DK1091938T3 - Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disse - Google Patents
Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disseInfo
- Publication number
- DK1091938T3 DK1091938T3 DK99928753.5T DK99928753T DK1091938T3 DK 1091938 T3 DK1091938 T3 DK 1091938T3 DK 99928753 T DK99928753 T DK 99928753T DK 1091938 T3 DK1091938 T3 DK 1091938T3
- Authority
- DK
- Denmark
- Prior art keywords
- intermediates
- preparation
- piperidine derivatives
- antihistamine
- antihistamine piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/90—Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated
- C07C233/91—Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated with carbon atoms of the carboxamide groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10954298A | 1998-07-02 | 1998-07-02 | |
| PCT/US1999/013693 WO2000001671A2 (en) | 1998-07-02 | 1999-06-17 | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1091938T3 true DK1091938T3 (da) | 2011-02-07 |
Family
ID=22328222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99928753.5T DK1091938T3 (da) | 1998-07-02 | 1999-06-17 | Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disse |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1091938B1 (da) |
| JP (1) | JP2002519411A (da) |
| KR (2) | KR100707904B1 (da) |
| CN (3) | CN101311165B (da) |
| AR (1) | AR019197A1 (da) |
| AT (1) | ATE485271T1 (da) |
| AU (1) | AU769284B2 (da) |
| BR (1) | BR9911794A (da) |
| CA (1) | CA2336380C (da) |
| DE (1) | DE69942876D1 (da) |
| DK (1) | DK1091938T3 (da) |
| ES (1) | ES2354968T3 (da) |
| HK (3) | HK1034065A1 (da) |
| HU (1) | HUP0104159A3 (da) |
| IL (6) | IL140649A0 (da) |
| NO (1) | NO319534B1 (da) |
| NZ (2) | NZ508477A (da) |
| PT (1) | PT1091938E (da) |
| TW (1) | TW533197B (da) |
| WO (1) | WO2000001671A2 (da) |
| ZA (1) | ZA200007034B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040044038A1 (en) | 2002-06-10 | 2004-03-04 | Barnaba Krochmal | Polymorphic form XVI of fexofenadine hydrochloride |
| CN101585768B (zh) * | 2009-06-06 | 2012-01-04 | 浙江大学宁波理工学院 | 合成2-[4-(4-氯丁酰基)苯基]-2-甲基丙酸酯的方法 |
| CN101585764B (zh) * | 2009-06-06 | 2012-02-15 | 浙江大学宁波理工学院 | 合成2—［4—(4—氯丁酰基)苯基］—2—甲基丙酸的方法 |
| CN101585767B (zh) * | 2009-06-06 | 2012-02-15 | 浙江大学宁波理工学院 | 一种合成2—[4—(4—氯丁酰基)苯基]—2—甲基丙酸酯的方法 |
| CN101585763B (zh) * | 2009-06-06 | 2012-01-04 | 浙江大学宁波理工学院 | 一种合成2-[4-(4-氯丁酰基)苯基]-2-甲基丙酸的方法 |
| EP2289867A3 (en) * | 2009-08-19 | 2012-04-25 | Jubilant Organosys Limited | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof |
| JP6192554B2 (ja) * | 2014-02-03 | 2017-09-06 | 三菱電機株式会社 | 真空断熱材の製造方法 |
| CN112661693A (zh) * | 2021-01-27 | 2021-04-16 | 西北农林科技大学 | 一种非索非那定的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3839431A (en) * | 1970-07-13 | 1974-10-01 | Squibb & Sons Inc | Cyclopropylmethylphenylacetic acids and derivatives |
| US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| MX9302076A (es) * | 1992-04-10 | 1994-03-31 | Merrell Dow Pharma | Proceso novedoso para preparar derivados de piperidina. |
| US5654433A (en) * | 1993-01-26 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Process for piperidine derivatives |
| JP3034047B2 (ja) * | 1993-06-24 | 2000-04-17 | オールバニー・モレキュラー・リサーチ・インコーポレイテッド | ピペリジン誘導体及びそれらの製造法 |
| HU226037B1 (en) * | 1993-06-25 | 2008-03-28 | Aventis Inc | Process for producing antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives and novel intermediates |
| CA2216877A1 (en) * | 1995-05-08 | 1996-11-14 | Hoechst Marion Roussel, Inc. | Alpha-(substituted alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol derivatives, their preparation and their use as anti-histamines, anti-allergy agents and bronchodilators |
-
1999
- 1999-06-17 CN CN2008100922352A patent/CN101311165B/zh not_active Expired - Fee Related
- 1999-06-17 AU AU45746/99A patent/AU769284B2/en not_active Ceased
- 1999-06-17 WO PCT/US1999/013693 patent/WO2000001671A2/en not_active Application Discontinuation
- 1999-06-17 DK DK99928753.5T patent/DK1091938T3/da active
- 1999-06-17 IL IL14064999A patent/IL140649A0/xx active IP Right Grant
- 1999-06-17 NZ NZ508477A patent/NZ508477A/en not_active IP Right Cessation
- 1999-06-17 AT AT99928753T patent/ATE485271T1/de active
- 1999-06-17 JP JP2000558076A patent/JP2002519411A/ja active Pending
- 1999-06-17 CN CNB2006100036278A patent/CN100522921C/zh not_active Expired - Fee Related
- 1999-06-17 PT PT99928753T patent/PT1091938E/pt unknown
- 1999-06-17 KR KR1020007015062A patent/KR100707904B1/ko not_active IP Right Cessation
- 1999-06-17 KR KR1020067006908A patent/KR100682447B1/ko not_active IP Right Cessation
- 1999-06-17 NZ NZ528839A patent/NZ528839A/en not_active IP Right Cessation
- 1999-06-17 ES ES99928753T patent/ES2354968T3/es not_active Expired - Lifetime
- 1999-06-17 EP EP99928753A patent/EP1091938B1/en not_active Expired - Lifetime
- 1999-06-17 DE DE69942876T patent/DE69942876D1/de not_active Expired - Lifetime
- 1999-06-17 CN CNB998081329A patent/CN1246312C/zh not_active Expired - Fee Related
- 1999-06-17 BR BR9911794-0A patent/BR9911794A/pt not_active Application Discontinuation
- 1999-06-17 CA CA002336380A patent/CA2336380C/en not_active Expired - Fee Related
- 1999-06-17 HU HU0104159A patent/HUP0104159A3/hu unknown
- 1999-06-29 TW TW088111017A patent/TW533197B/zh not_active IP Right Cessation
- 1999-06-30 AR ARP990103193A patent/AR019197A1/es active IP Right Grant
-
2000
- 2000-11-29 ZA ZA200007034A patent/ZA200007034B/en unknown
- 2000-12-29 NO NO20006694A patent/NO319534B1/no not_active IP Right Cessation
- 2000-12-31 IL IL140649A patent/IL140649A/en not_active IP Right Cessation
-
2001
- 2001-04-23 HK HK01102844.3A patent/HK1034065A1/xx not_active IP Right Cessation
-
2005
- 2005-09-22 IL IL171062A patent/IL171062A/en not_active IP Right Cessation
- 2005-09-22 IL IL171063A patent/IL171063A/en not_active IP Right Cessation
- 2005-09-22 IL IL171061A patent/IL171061A/en not_active IP Right Cessation
- 2005-10-19 IL IL171479A patent/IL171479A/en not_active IP Right Cessation
-
2006
- 2006-11-01 HK HK06112043.6A patent/HK1091806A1/xx not_active IP Right Cessation
-
2009
- 2009-05-12 HK HK09104335.7A patent/HK1125382A1/xx not_active IP Right Cessation
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