DK1091938T3 - Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disse - Google Patents
Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disseInfo
- Publication number
- DK1091938T3 DK1091938T3 DK99928753.5T DK99928753T DK1091938T3 DK 1091938 T3 DK1091938 T3 DK 1091938T3 DK 99928753 T DK99928753 T DK 99928753T DK 1091938 T3 DK1091938 T3 DK 1091938T3
- Authority
- DK
- Denmark
- Prior art keywords
- intermediates
- preparation
- piperidine derivatives
- antihistamine
- antihistamine piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/90—Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated
- C07C233/91—Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated with carbon atoms of the carboxamide groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10954298A | 1998-07-02 | 1998-07-02 | |
| PCT/US1999/013693 WO2000001671A2 (en) | 1998-07-02 | 1999-06-17 | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1091938T3 true DK1091938T3 (da) | 2011-02-07 |
Family
ID=22328222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99928753.5T DK1091938T3 (da) | 1998-07-02 | 1999-06-17 | Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disse |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1091938B1 (da) |
| JP (1) | JP2002519411A (da) |
| KR (2) | KR100707904B1 (da) |
| CN (3) | CN1246312C (da) |
| AR (1) | AR019197A1 (da) |
| AT (1) | ATE485271T1 (da) |
| AU (1) | AU769284B2 (da) |
| BR (1) | BR9911794A (da) |
| CA (1) | CA2336380C (da) |
| DE (1) | DE69942876D1 (da) |
| DK (1) | DK1091938T3 (da) |
| ES (1) | ES2354968T3 (da) |
| HK (3) | HK1034065A1 (da) |
| HU (1) | HUP0104159A3 (da) |
| IL (6) | IL140649A0 (da) |
| NO (1) | NO319534B1 (da) |
| NZ (2) | NZ508477A (da) |
| PT (1) | PT1091938E (da) |
| TW (1) | TW533197B (da) |
| WO (1) | WO2000001671A2 (da) |
| ZA (1) | ZA200007034B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005532356A (ja) | 2002-06-10 | 2005-10-27 | テバ ファーマシューティカル インダストリーズ リミティド | 塩酸フェキソフェナジンの多型体ｘｖｉ |
| CN101585763B (zh) * | 2009-06-06 | 2012-01-04 | 浙江大学宁波理工学院 | 一种合成2-[4-(4-氯丁酰基)苯基]-2-甲基丙酸的方法 |
| CN101585768B (zh) * | 2009-06-06 | 2012-01-04 | 浙江大学宁波理工学院 | 合成2-[4-(4-氯丁酰基)苯基]-2-甲基丙酸酯的方法 |
| CN101585764B (zh) * | 2009-06-06 | 2012-02-15 | 浙江大学宁波理工学院 | 合成2—［4—(4—氯丁酰基)苯基］—2—甲基丙酸的方法 |
| CN101585767B (zh) * | 2009-06-06 | 2012-02-15 | 浙江大学宁波理工学院 | 一种合成2—[4—(4—氯丁酰基)苯基]—2—甲基丙酸酯的方法 |
| EP2289867A3 (en) * | 2009-08-19 | 2012-04-25 | Jubilant Organosys Limited | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof |
| JP6192554B2 (ja) * | 2014-02-03 | 2017-09-06 | 三菱電機株式会社 | 真空断熱材の製造方法 |
| CN112661693A (zh) * | 2021-01-27 | 2021-04-16 | 西北农林科技大学 | 一种非索非那定的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3839431A (en) * | 1970-07-13 | 1974-10-01 | Squibb & Sons Inc | Cyclopropylmethylphenylacetic acids and derivatives |
| US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| EP0635004B1 (en) * | 1992-04-10 | 2002-07-17 | Merrell Pharmaceuticals Inc. | 4-diphenylmethyl piperidine derivatives and process for their preparation |
| US5654433A (en) * | 1993-01-26 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Process for piperidine derivatives |
| EP0703902B1 (en) * | 1993-06-24 | 1998-12-16 | Albany Molecular Research, Inc. | Process for the production of piperidine derivatives |
| CA2362337C (en) * | 1993-06-25 | 2005-08-02 | Merrell Pharmaceuticals Inc. | Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives |
| CN1183769A (zh) * | 1995-05-08 | 1998-06-03 | 赫彻斯特马里恩鲁斯公司 | α-(取代的烷基苯基)-4-(羟基二苯基甲基)-1-哌啶丁醇衍生物,其制备和其用作抗组胺剂、抗变应性剂和支气管扩张药的用途 |
-
1999
- 1999-06-17 DK DK99928753.5T patent/DK1091938T3/da active
- 1999-06-17 CN CNB998081329A patent/CN1246312C/zh not_active Expired - Fee Related
- 1999-06-17 HU HU0104159A patent/HUP0104159A3/hu unknown
- 1999-06-17 CN CN2008100922352A patent/CN101311165B/zh not_active Expired - Fee Related
- 1999-06-17 EP EP99928753A patent/EP1091938B1/en not_active Expired - Lifetime
- 1999-06-17 CA CA002336380A patent/CA2336380C/en not_active Expired - Fee Related
- 1999-06-17 KR KR1020007015062A patent/KR100707904B1/ko not_active IP Right Cessation
- 1999-06-17 CN CNB2006100036278A patent/CN100522921C/zh not_active Expired - Fee Related
- 1999-06-17 PT PT99928753T patent/PT1091938E/pt unknown
- 1999-06-17 AT AT99928753T patent/ATE485271T1/de active
- 1999-06-17 AU AU45746/99A patent/AU769284B2/en not_active Ceased
- 1999-06-17 WO PCT/US1999/013693 patent/WO2000001671A2/en not_active Application Discontinuation
- 1999-06-17 NZ NZ508477A patent/NZ508477A/en not_active IP Right Cessation
- 1999-06-17 NZ NZ528839A patent/NZ528839A/en not_active IP Right Cessation
- 1999-06-17 KR KR1020067006908A patent/KR100682447B1/ko not_active IP Right Cessation
- 1999-06-17 ES ES99928753T patent/ES2354968T3/es not_active Expired - Lifetime
- 1999-06-17 IL IL14064999A patent/IL140649A0/xx active IP Right Grant
- 1999-06-17 DE DE69942876T patent/DE69942876D1/de not_active Expired - Lifetime
- 1999-06-17 BR BR9911794-0A patent/BR9911794A/pt not_active Application Discontinuation
- 1999-06-17 JP JP2000558076A patent/JP2002519411A/ja active Pending
- 1999-06-29 TW TW088111017A patent/TW533197B/zh not_active IP Right Cessation
- 1999-06-30 AR ARP990103193A patent/AR019197A1/es active IP Right Grant
-
2000
- 2000-11-29 ZA ZA200007034A patent/ZA200007034B/en unknown
- 2000-12-29 NO NO20006694A patent/NO319534B1/no not_active IP Right Cessation
- 2000-12-31 IL IL140649A patent/IL140649A/en not_active IP Right Cessation
-
2001
- 2001-04-23 HK HK01102844.3A patent/HK1034065A1/xx not_active IP Right Cessation
-
2005
- 2005-09-22 IL IL171061A patent/IL171061A/en not_active IP Right Cessation
- 2005-09-22 IL IL171062A patent/IL171062A/en not_active IP Right Cessation
- 2005-09-22 IL IL171063A patent/IL171063A/en not_active IP Right Cessation
- 2005-10-19 IL IL171479A patent/IL171479A/en not_active IP Right Cessation
-
2006
- 2006-11-01 HK HK06112043.6A patent/HK1091806A1/xx not_active IP Right Cessation
-
2009
- 2009-05-12 HK HK09104335.7A patent/HK1125382A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS5197A (is) | Nikótínamíð afleiður | |
| DK0975708T3 (da) | Fremgangsmåder og materialer til nedbrydning af xanthan | |
| DK1454907T3 (da) | Quninazolin og pyridopyrmidin-derivativer | |
| NO20000627D0 (no) | ForhÕndsbelagte kontrollert - frigjørings - gjødningsmidler og fremgangsmÕter for deres fremstilling | |
| IS6385A (is) | Ný notkun og nýjar N-asabísýkló-amíð afleiður | |
| DE69906311D1 (de) | Diarylbenzopyranderivate als cyclooxygenase-2-inhibitoren | |
| NO20003067D0 (no) | Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstilling | |
| ATE278695T1 (de) | Piperidinderivate | |
| DK1015444T3 (da) | Pyrimidinderivater og fremgangsmåder til fremstilling deraf | |
| IS6401A (is) | Efnafræðilegar aðferðir og milliefni | |
| DK1091938T3 (da) | Antihistamin piperidinderivativer og mellemprodukter til fremstilling af disse | |
| DK0999025T3 (da) | Fremgangsmåde til fremstilling af profilerede og laminerede materialer | |
| ATE225346T1 (de) | Fkbp inhibitoren | |
| DK0864564T3 (da) | Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater | |
| DK0983249T3 (da) | Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater | |
| ATE315025T1 (de) | Ethansulfonyl-piperidin-derivate | |
| DE59803628D1 (de) | Modulare brücke | |
| DE69918307D1 (de) | Modulare lesebrille | |
| NO20031177L (no) | Fremgangsmåter og sammensetninger for glykosidaseanalyser | |
| NO992302D0 (no) | Piperidin-derivater | |
| DK0930297T3 (da) | Fremgangsmåde til fremstilling af naphtyridoner og mellemprodukter | |
| NO20001778D0 (no) | Substituerte piperidinderivater | |
| NO993168L (no) | Broennramme | |
| DK92697A (da) | Redskab og fremgangsmåde til fremstilling af samme | |
| DK1037892T3 (da) | Piperidinderivater |