ES2086442T3 - Derivados de fluoroetilcamptotecina. - Google Patents

Derivados de fluoroetilcamptotecina.

Info

Publication number
ES2086442T3
ES2086442T3 ES91113652T ES91113652T ES2086442T3 ES 2086442 T3 ES2086442 T3 ES 2086442T3 ES 91113652 T ES91113652 T ES 91113652T ES 91113652 T ES91113652 T ES 91113652T ES 2086442 T3 ES2086442 T3 ES 2086442T3
Authority
ES
Spain
Prior art keywords
fluoroetilcamptotecina
derivatives
following general
derivative
piranoindolizine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91113652T
Other languages
English (en)
Inventor
Asahina Yoshikazu
Obi Kikoh
Oomori Yasuo
Okazaki Takashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2086442T3 publication Critical patent/ES2086442T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Abstract

UN NUEVO COMPUESTO REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL (I): EL COMPUESTO TIENE ACTIVIDADES ANTINEOPLASTICAS Y UNA BAJA TOXICIDAD. DERIVADO DE PIRANOINDOLIZINA QUE TIENE LAS SIGUIENTES FORMULAS GENERALES (II) O (III): Y UN PROCESO PARA LA PRODUCCION DEL DERIVADO DE PIRANOINDOLIZINA.
ES91113652T 1990-08-14 1991-08-14 Derivados de fluoroetilcamptotecina. Expired - Lifetime ES2086442T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21521490 1990-08-14

Publications (1)

Publication Number Publication Date
ES2086442T3 true ES2086442T3 (es) 1996-07-01

Family

ID=16668588

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91113652T Expired - Lifetime ES2086442T3 (es) 1990-08-14 1991-08-14 Derivados de fluoroetilcamptotecina.

Country Status (7)

Country Link
EP (1) EP0471358B1 (es)
KR (1) KR960002854B1 (es)
CN (1) CN1031941C (es)
CA (1) CA2048896C (es)
DE (1) DE69119323T2 (es)
ES (1) ES2086442T3 (es)
HU (1) HU213136B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT70024A (en) * 1990-09-28 1995-09-28 Smithkline Beecham Corp Process for preparing water soluble camptothecin analogs
AP9300587A0 (en) * 1992-11-12 1995-05-05 Glaxo Inc Water soluble camptothecin derivatives.
US5663177A (en) * 1995-05-31 1997-09-02 Smithkline Beecham Corporation Water soluble camptothecin analogs
JPH08333370A (ja) * 1995-06-08 1996-12-17 Kyorin Pharmaceut Co Ltd 水に可溶な新規フルオロエチルカンプトテシン誘導体、及びその製造方法
SG116433A1 (en) 1996-10-30 2005-11-28 Tanabe Seiyaku Co S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof.
IN189180B (es) * 1997-07-09 2003-01-04 Chong Kun Dang Corp
UA80409C2 (en) 2001-11-30 2007-09-25 Chugai Pharmaceutical Co Ltd Hexacyclic compounds
UA88008C2 (en) 2004-04-09 2009-09-10 Чугей Сейяку Кабусики Кайся Water-soluble prodrugs
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
US8093265B2 (en) 2007-03-09 2012-01-10 Renovis, Inc. Bicycloheteroaryl compounds as P2X7 modulators and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0220601B1 (en) * 1985-10-21 1991-12-11 Daiichi Seiyaku Co., Ltd. Pyranoindolizine derivatives and preparation process thereof
JPH0615547B2 (ja) * 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体

Also Published As

Publication number Publication date
AU638347B2 (en) 1993-06-24
AU8161891A (en) 1992-02-20
KR920004392A (ko) 1992-03-27
EP0471358B1 (en) 1996-05-08
DE69119323D1 (de) 1996-06-13
EP0471358A1 (en) 1992-02-19
HU213136B (en) 1997-02-28
KR960002854B1 (ko) 1996-02-27
HU912639D0 (en) 1992-01-28
CN1060095A (zh) 1992-04-08
CN1031941C (zh) 1996-06-05
DE69119323T2 (de) 1996-11-14
CA2048896A1 (en) 1992-02-15
HUT63425A (en) 1993-08-30
CA2048896C (en) 1999-11-16

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