DE69119323D1 - Fluoräthylcamptothecinderivate - Google Patents

Fluoräthylcamptothecinderivate

Info

Publication number
DE69119323D1
DE69119323D1 DE69119323T DE69119323T DE69119323D1 DE 69119323 D1 DE69119323 D1 DE 69119323D1 DE 69119323 T DE69119323 T DE 69119323T DE 69119323 T DE69119323 T DE 69119323T DE 69119323 D1 DE69119323 D1 DE 69119323D1
Authority
DE
Germany
Prior art keywords
fluoroethyl
camptothecin derivatives
camptothecin
derivatives
fluoroethyl camptothecin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69119323T
Other languages
English (en)
Other versions
DE69119323T2 (de
Inventor
Asahina Yoshikazu
Obi Kikoh
Oomori Yasuo
Okazaki Takashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69119323D1 publication Critical patent/DE69119323D1/de
Publication of DE69119323T2 publication Critical patent/DE69119323T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69119323T 1990-08-14 1991-08-14 Fluoräthylcamptothecinderivate Expired - Fee Related DE69119323T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21521490 1990-08-14

Publications (2)

Publication Number Publication Date
DE69119323D1 true DE69119323D1 (de) 1996-06-13
DE69119323T2 DE69119323T2 (de) 1996-11-14

Family

ID=16668588

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69119323T Expired - Fee Related DE69119323T2 (de) 1990-08-14 1991-08-14 Fluoräthylcamptothecinderivate

Country Status (7)

Country Link
EP (1) EP0471358B1 (de)
KR (1) KR960002854B1 (de)
CN (1) CN1031941C (de)
CA (1) CA2048896C (de)
DE (1) DE69119323T2 (de)
ES (1) ES2086442T3 (de)
HU (1) HU213136B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2848958B2 (ja) * 1990-09-28 1999-01-20 スミスクライン・ビーチャム・コーポレイション 水溶性カンプトテシン類似体、方法および手段
AP9300587A0 (en) * 1992-11-12 1995-05-05 Glaxo Inc Water soluble camptothecin derivatives.
US5663177A (en) * 1995-05-31 1997-09-02 Smithkline Beecham Corporation Water soluble camptothecin analogs
JPH08333370A (ja) * 1995-06-08 1996-12-17 Kyorin Pharmaceut Co Ltd 水に可溶な新規フルオロエチルカンプトテシン誘導体、及びその製造方法
SG104284A1 (en) 1996-10-30 2004-06-21 Tanabe Seiyaku Co S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof
IN189180B (de) * 1997-07-09 2003-01-04 Chong Kun Dang Corp
KR100895746B1 (ko) 2001-11-30 2009-04-30 추가이 세이야쿠 가부시키가이샤 헥사사이클릭 화합물
NZ550665A (en) 2004-04-09 2010-05-28 Chugai Pharmaceutical Co Ltd Novel water-soluble prodrugs of camptothecin derivatives
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
EP2124562B1 (de) 2007-03-09 2016-04-20 Second Genome, Inc. Bicycloheteroarylverbindungen als px27-modulatoren und ihre verwendungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3682874D1 (de) * 1985-10-21 1992-01-23 Daiichi Seiyaku Co Pyranoindolizinderivate und verfahren zu ihrer herstellung.
JPH0615547B2 (ja) * 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体

Also Published As

Publication number Publication date
AU8161891A (en) 1992-02-20
AU638347B2 (en) 1993-06-24
KR920004392A (ko) 1992-03-27
ES2086442T3 (es) 1996-07-01
DE69119323T2 (de) 1996-11-14
CN1031941C (zh) 1996-06-05
EP0471358A1 (de) 1992-02-19
CA2048896A1 (en) 1992-02-15
CN1060095A (zh) 1992-04-08
KR960002854B1 (ko) 1996-02-27
HUT63425A (en) 1993-08-30
CA2048896C (en) 1999-11-16
HU912639D0 (en) 1992-01-28
EP0471358B1 (de) 1996-05-08
HU213136B (en) 1997-02-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee