ES2167503T3 - Procedimiento para la preparacion de la amida de acido nicotinico. - Google Patents

Procedimiento para la preparacion de la amida de acido nicotinico.

Info

Publication number
ES2167503T3
ES2167503T3 ES96117280T ES96117280T ES2167503T3 ES 2167503 T3 ES2167503 T3 ES 2167503T3 ES 96117280 T ES96117280 T ES 96117280T ES 96117280 T ES96117280 T ES 96117280T ES 2167503 T3 ES2167503 T3 ES 2167503T3
Authority
ES
Spain
Prior art keywords
nicotinic acid
procedure
amic
preparation
transformed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96117280T
Other languages
English (en)
Inventor
Josef Dr Heveling
Erich Dr Armbruster
Lukas Dr Utiger
Markus Dr Rohner
Hans-Rudolf Dr Dettwiler
Roderick John Dr Chuck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2167503T3 publication Critical patent/ES2167503T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCEDIMIENTO PARA LA OBTENCION DE LA AMIDA DEL ACIDO NICOTINICO, EN EL CUAL EN UNA PRIMERA ETAPA 2METIL-1,5-DIAMINOPENTANO SE TRANSFORMA CATALITICAMENTE EN 3PICOLINA, LA 3-PICOLINA SE TRANSFORMA EN 3-CIANOPIRIDINA MEDIANTE UNA AMONOXIDACION, Y FINALMENTE LA 3-CIANOPIRIDINA SE TRANSFORMA MICROBIOLOGICAMENTE EN EL PRODUCTO FINAL.
ES96117280T 1995-11-01 1996-10-28 Procedimiento para la preparacion de la amida de acido nicotinico. Expired - Lifetime ES2167503T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH309095 1995-11-01

Publications (1)

Publication Number Publication Date
ES2167503T3 true ES2167503T3 (es) 2002-05-16

Family

ID=4248403

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96117280T Expired - Lifetime ES2167503T3 (es) 1995-11-01 1996-10-28 Procedimiento para la preparacion de la amida de acido nicotinico.

Country Status (28)

Country Link
US (1) US5719045A (es)
EP (1) EP0770687B1 (es)
JP (1) JP3911734B2 (es)
CN (1) CN1149199C (es)
AR (1) AR004260A1 (es)
AT (1) ATE212380T1 (es)
AU (1) AU700409B2 (es)
BG (1) BG63314B1 (es)
BR (1) BR9605410A (es)
CA (1) CA2187979C (es)
CZ (1) CZ290836B6 (es)
DE (1) DE59608641D1 (es)
DK (1) DK0770687T3 (es)
EE (1) EE03573B1 (es)
ES (1) ES2167503T3 (es)
HU (1) HU217689B (es)
IL (1) IL119402A (es)
MX (1) MX9605272A (es)
MY (1) MY119113A (es)
NO (1) NO318584B1 (es)
PL (1) PL185286B1 (es)
PT (1) PT770687E (es)
RU (1) RU2177474C2 (es)
SI (1) SI0770687T1 (es)
SK (1) SK283653B6 (es)
TR (1) TR199600857A2 (es)
TW (1) TW409148B (es)
ZA (1) ZA968485B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863750A (en) * 1996-12-18 1999-01-26 Cytec Tech Corp Methods for the detoxification of nitrile and/or amide compounds
JP4476390B2 (ja) * 1998-09-04 2010-06-09 株式会社半導体エネルギー研究所 半導体装置の作製方法
US20050089987A1 (en) * 2003-10-27 2005-04-28 Lonza Ltd. Polyacryamide beads containing encapsulated cells
WO2007093533A2 (de) * 2006-02-15 2007-08-23 Basf Se Verfahren zur dehydrierung
EP2049492B1 (en) * 2006-08-08 2010-01-27 Dow AgroSciences LLC Method of making cyanopyridines
EP2305377A1 (en) * 2009-09-29 2011-04-06 Lonza Ltd. Catalysts for the preparation of cyanopyridines and their use
EP2319833A1 (en) * 2009-10-16 2011-05-11 Lonza Ltd. Methods and devices for the production of aqueous solutions of cyanopyridines
EP2322273A1 (en) 2009-10-16 2011-05-18 Lonza Ltd. Catalysts for the preparation of methylpyridine
EP2319834A1 (en) * 2009-10-16 2011-05-11 Lonza Ltd. Methods and devices for the production of aqueous solutions of cyanopyridines
US8530664B2 (en) 2009-10-16 2013-09-10 Lonza Ltd. Catalysts for the preparation of methylpyridine
CN102219734B (zh) * 2011-05-10 2013-08-07 浙江爱迪亚营养科技开发有限公司 一种烟酰胺的制备方法
CN103804284B (zh) * 2013-01-07 2015-12-02 清华大学 用于制备3-甲基吡啶的系统
CN104844539B (zh) * 2014-02-17 2018-08-24 上海凯赛生物技术研发中心有限公司 一种哌啶的制备方法
CN104762340A (zh) * 2015-03-17 2015-07-08 安徽瑞邦生物科技有限公司 一种利用固定化细胞将烟腈转化为烟酰胺的方法
US11185545B2 (en) 2017-03-31 2021-11-30 Merck Patent Gmbh Crystalline monosodium salt of 5-methyl-(6S)-tetrahydrofolic acid
CN110461845B (zh) 2017-03-31 2023-05-12 默克专利股份有限公司 5-甲基-（6s）-四氢叶酸的结晶钠盐
CN112010802B (zh) * 2020-08-13 2022-03-29 浙江新和成股份有限公司 3-甲基吡啶的连续制备方法
CN111995572A (zh) * 2020-08-19 2020-11-27 广州黛诗莎化妆品有限公司 一种美白祛斑加强型的烟酰胺结晶提取工艺
CN117942976B (zh) * 2024-03-27 2024-06-14 北京弗莱明科技有限公司 一种氨氧化反应催化剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028713A (en) * 1983-12-08 1991-07-02 The Standard Oil Company Ammoxidation of methyl substituted heteroaromatics to make heteroaromatic nitriles
US5179014A (en) * 1985-01-08 1993-01-12 Nitto Chemical Industry Co., Ltd. Process for the preparation of amides using microorganisms
JPS61162193A (ja) * 1985-01-08 1986-07-22 Nitto Chem Ind Co Ltd 微生物によるアミド類の製造法
DD274631A5 (de) * 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
US5258305A (en) * 1991-09-13 1993-11-02 Nitto Chemical Industry Co., Ltd. Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi
GEP20012441B (en) * 1993-04-02 2001-05-25 Lonza Ag Process for Preparing 3-Methylpiperidine and 3-Methylpyridine
CZ338596A3 (en) * 1994-05-23 1997-07-16 Lonza Ag Catalytic mixture for oxidative amonolysis of alkyl pyridines, process of its preparation and use

Also Published As

Publication number Publication date
NO964611L (no) 1997-05-02
CA2187979C (en) 2007-04-17
DK0770687T3 (da) 2002-04-22
TW409148B (en) 2000-10-21
HUP9603029A2 (en) 1997-09-29
CZ317396A3 (en) 1997-05-14
SK140596A3 (en) 1997-07-09
PL185286B1 (pl) 2003-04-30
ATE212380T1 (de) 2002-02-15
IL119402A0 (en) 1997-01-10
SK283653B6 (sk) 2003-11-04
EP0770687B1 (de) 2002-01-23
TR199600857A2 (tr) 1997-05-21
CZ290836B6 (cs) 2002-10-16
EE03573B1 (et) 2001-12-17
CN1149199C (zh) 2004-05-12
BR9605410A (pt) 1998-08-04
US5719045A (en) 1998-02-17
AU700409B2 (en) 1999-01-07
PT770687E (pt) 2002-07-31
SI0770687T1 (en) 2002-04-30
IL119402A (en) 2000-10-31
RU2177474C2 (ru) 2001-12-27
DE59608641D1 (de) 2002-03-14
NO318584B1 (no) 2005-04-11
HU217689B (hu) 2000-03-28
HU9603029D0 (en) 1996-12-30
BG63314B1 (bg) 2001-09-28
AU7034896A (en) 1997-05-08
EP0770687A2 (de) 1997-05-02
CA2187979A1 (en) 1997-05-02
EE9600153A (et) 1997-06-16
ZA968485B (en) 1997-05-20
AR004260A1 (es) 1998-11-04
NO964611D0 (no) 1996-10-31
CN1154364A (zh) 1997-07-16
JP3911734B2 (ja) 2007-05-09
PL316778A1 (en) 1997-05-12
BG100942A (en) 1997-11-28
MX9605272A (es) 1997-05-31
MY119113A (en) 2005-03-31
JPH09163995A (ja) 1997-06-24
EP0770687A3 (de) 1998-08-19
HUP9603029A3 (en) 1999-03-01

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