MX9706283A - Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo. - Google Patents

Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo.

Info

Publication number
MX9706283A
MX9706283A MX9706283A MX9706283A MX9706283A MX 9706283 A MX9706283 A MX 9706283A MX 9706283 A MX9706283 A MX 9706283A MX 9706283 A MX9706283 A MX 9706283A MX 9706283 A MX9706283 A MX 9706283A
Authority
MX
Mexico
Prior art keywords
processs
employment
preparation
empiric formula
polyene antibiotics
Prior art date
Application number
MX9706283A
Other languages
English (en)
Other versions
MXPA97006283A (es
Inventor
Lssszlo Vertesy
Michael Kurz
Joachim Wink
Astrid Markus
Wilhelm Stahl
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MXPA97006283A publication Critical patent/MXPA97006283A/es
Publication of MX9706283A publication Critical patent/MX9706283A/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
    • Y10S435/892Streptomyces candidus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Compuestos de las formulas, 3874 H1, formula empírica: C58H86N2O18, PM 1099,3 3874 H2, formula empírica; C59H88N2O18, PM 1113,3 3874 H3, formula empírica: C57H87NO18, PM 1074, 3 3874 H4, formula empírica: C58H84N2O18, PM 1097, 3 3874 H5, formula empírica: C59H86N2O18, PM 1111, 3 3874 H6, formula empírica: C57H85NO18, PM 1072, 3, son adecuados para el tratamiento de enfermedades por hongos y para el tratamiento de enfermedades que van acompañadas de una concentracion incrementada de esteroides.
MX9706283A 1996-08-19 1997-08-18 Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo. MX9706283A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19633310.5 1996-08-19
DE19633310 1996-08-19
DE19649349.8 1996-11-28
DE19649349 1996-11-28

Publications (2)

Publication Number Publication Date
MXPA97006283A MXPA97006283A (es) 1998-02-01
MX9706283A true MX9706283A (es) 1998-02-28

Family

ID=26028529

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9706283A MX9706283A (es) 1996-08-19 1997-08-18 Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo.

Country Status (15)

Country Link
US (1) US5939399A (es)
EP (2) EP0829486A2 (es)
JP (1) JPH10120686A (es)
KR (1) KR19980018741A (es)
CN (1) CN1127508C (es)
AT (1) ATE233781T1 (es)
AU (1) AU721483B2 (es)
BR (1) BR9704385A (es)
CA (1) CA2213285A1 (es)
DE (1) DE59709428D1 (es)
DK (1) DK0829487T3 (es)
ES (1) ES2194152T3 (es)
MX (1) MX9706283A (es)
PT (1) PT829487E (es)
TW (1) TW514664B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051061A1 (en) 2000-01-14 2001-07-19 Intrabiotics Pharmaceuticals, Inc. Derivatives of polyene macrolides and preparation and use thereof
US20030104977A1 (en) * 2000-03-31 2003-06-05 Ugo Ripamonti Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
US6575926B2 (en) 2000-12-15 2003-06-10 Bonutti 2003 Trust-A Myofascial strap
US7654551B2 (en) * 2007-02-02 2010-02-02 Page James H Skid steer attachment system
US8608926B2 (en) * 2008-11-20 2013-12-17 Neroxis Sa Amperometric in-pipe electrochemical sensing probe
CN104745651B (zh) * 2015-03-30 2018-03-27 嘉应学院 用于多产色链霉菌发酵生产多烯大环内酯类抗真菌抗生素的发酵培养基及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4027015A (en) * 1974-03-11 1977-05-31 Schering Corporation Antibiotic 67-121, a polyene antifungal antibiotic produced by actinoplanes caeruleus
GB1485207A (en) * 1975-05-28 1977-09-08 Ucb Sa Anti-fungal agent lucknomycine
US4272525A (en) * 1978-10-23 1981-06-09 Schering Corporation Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
ZA795508B (en) * 1978-10-23 1981-05-27 Schering Corp Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
IT1243404B (it) * 1990-12-03 1994-06-10 Prodotti Antibiotici Spa Derivati della partricina
JP3188325B2 (ja) * 1992-10-28 2001-07-16 理化学研究所 ポリエンマクロライド物質、その製造法、及びこれを用いた抗菌剤と抗腫瘍剤
JPH06239848A (ja) * 1993-02-19 1994-08-30 Taisho Pharmaceut Co Ltd ポリエン系化合物

Also Published As

Publication number Publication date
AU3423097A (en) 1998-02-26
DE59709428D1 (de) 2003-04-10
PT829487E (pt) 2003-07-31
ATE233781T1 (de) 2003-03-15
CN1127508C (zh) 2003-11-12
EP0829487B1 (de) 2003-03-05
AU721483B2 (en) 2000-07-06
US5939399A (en) 1999-08-17
BR9704385A (pt) 1999-05-11
EP0829487A3 (de) 1998-09-09
JPH10120686A (ja) 1998-05-12
CN1177597A (zh) 1998-04-01
DK0829487T3 (da) 2003-06-23
ES2194152T3 (es) 2003-11-16
CA2213285A1 (en) 1998-02-19
EP0829487A2 (de) 1998-03-18
KR19980018741A (ko) 1998-06-05
TW514664B (en) 2002-12-21
EP0829486A2 (de) 1998-03-18

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