YU49287B - Soli derivata indola - Google Patents

Soli derivata indola

Info

Publication number
YU49287B
YU49287B YU56995A YU56995A YU49287B YU 49287 B YU49287 B YU 49287B YU 56995 A YU56995 A YU 56995A YU 56995 A YU56995 A YU 56995A YU 49287 B YU49287 B YU 49287B
Authority
YU
Yugoslavia
Prior art keywords
indole
salt derivatives
compound
infra
twelve
Prior art date
Application number
YU56995A
Other languages
English (en)
Other versions
YU56995A (sh
Inventor
Valerie Denise Harding
Ross James Macrae
Ronald James Ogilvie
Original Assignee
Pfizer Research And Development Company N.V./S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10760474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU49287(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Research And Development Company N.V./S.A. filed Critical Pfizer Research And Development Company N.V./S.A.
Publication of YU56995A publication Critical patent/YU56995A/sh
Publication of YU49287B publication Critical patent/YU49287B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Reciprocating, Oscillating Or Vibrating Motors (AREA)

Abstract

Jedinjenje formule (I): Kristalni, α-polimorfni oblik jedinjenja prema zahtevu 1, naznačen time, što ga karakteriše infra-crveni spektar koji pokazuje značajne apsorpcione trake ν=3371, 3293, 2713, 2524, 1419, 1343, 1307, 1264, 1151, 1086, 1020, 1008, 999, 922, 900, 805, 758, 740, 728, 689, 672, 652, 640, 598, 581, 573, 531, 498, 465, 457, 443, 428, 422, 414 i 399 cm-1. Prijava sadrži još tri nezavisna i dvanaest zavisnih patentnih zahteva.
YU56995A 1994-08-27 1995-08-25 Soli derivata indola YU49287B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9417310A GB9417310D0 (en) 1994-08-27 1994-08-27 Therapeutic agents

Publications (2)

Publication Number Publication Date
YU56995A YU56995A (sh) 1998-07-10
YU49287B true YU49287B (sh) 2005-03-15

Family

ID=10760474

Family Applications (1)

Application Number Title Priority Date Filing Date
YU56995A YU49287B (sh) 1994-08-27 1995-08-25 Soli derivata indola

Country Status (45)

Country Link
US (2) US6110940A (sh)
EP (1) EP0776323B1 (sh)
JP (1) JP2904588B2 (sh)
KR (1) KR100228952B1 (sh)
CN (1) CN1066727C (sh)
AP (1) AP576A (sh)
AT (1) ATE163182T1 (sh)
AU (1) AU691005B2 (sh)
BG (1) BG61840B1 (sh)
BR (1) BRPI9503812B1 (sh)
CA (1) CA2198599C (sh)
CO (1) CO4410334A1 (sh)
CZ (1) CZ287693B6 (sh)
DE (1) DE69501620T2 (sh)
DK (1) DK0776323T3 (sh)
DZ (1) DZ1923A1 (sh)
EG (1) EG23822A (sh)
ES (1) ES2112650T3 (sh)
FI (1) FI113768B (sh)
GB (1) GB9417310D0 (sh)
GR (1) GR3026475T3 (sh)
HR (1) HRP950460B1 (sh)
HU (1) HU227822B1 (sh)
IL (1) IL115013A (sh)
IS (1) IS1850B (sh)
LV (1) LV11800B (sh)
MA (1) MA23650A1 (sh)
MX (1) MX9701538A (sh)
MY (1) MY113733A (sh)
NO (1) NO311297B1 (sh)
NZ (1) NZ288210A (sh)
OA (1) OA10600A (sh)
PE (1) PE41596A1 (sh)
PL (1) PL180867B1 (sh)
RO (1) RO116400B1 (sh)
RU (1) RU2159241C2 (sh)
SA (1) SA95160156B1 (sh)
SI (1) SI9520091B (sh)
SK (1) SK282922B6 (sh)
TN (1) TNSN95092A1 (sh)
TR (1) TR199501061A2 (sh)
UA (1) UA45980C2 (sh)
WO (1) WO1996006842A1 (sh)
YU (1) YU49287B (sh)
ZA (1) ZA957142B (sh)

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GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9922963D0 (en) * 1999-09-28 1999-12-01 Pfizer Ltd Polymorphic salt
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
GB9923314D0 (en) 1999-10-01 1999-12-08 Pfizer Ltd Acylation process
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
US6977723B2 (en) 2000-01-07 2005-12-20 Transform Pharmaceuticals, Inc. Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
US7108970B2 (en) 2000-01-07 2006-09-19 Transform Pharmaceuticals, Inc. Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
GB0008563D0 (en) 2000-04-07 2000-05-24 Cambridge Discovery Chemistry Investigating different physical and/or chemical forms of materials
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
US20030166704A1 (en) * 2000-12-20 2003-09-04 Pfizer Inc. New process
US6579898B2 (en) 2001-03-01 2003-06-17 Pfizer Inc. Compositions having improved bioavailability
MXPA05010070A (es) 2003-04-11 2005-11-23 Pfizer Combinacion farmaceutica.
US7132549B2 (en) 2003-05-30 2006-11-07 Pfizer Inc. Process
GB0312478D0 (en) * 2003-05-30 2003-07-09 Pfizer Ltd Improved process
GB0317229D0 (en) * 2003-07-23 2003-08-27 Pfizer Ltd Improved process
US6927296B2 (en) 2003-07-23 2005-08-09 Pfizer Inc. Process
NZ561375A (en) * 2005-06-27 2011-06-30 Biovail Lab Int Srl Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound
CA2666149A1 (en) * 2006-10-19 2008-04-24 Auspex Pharmaceuticals, Inc. Substituted indoles
US20080139510A1 (en) * 2006-12-07 2008-06-12 Abe Rose Treatment of migraine headaches with sublingual amino acids
EP1956018A1 (de) * 2007-02-06 2008-08-13 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung eines Benzimidazolderivats
US20080287519A1 (en) * 2007-05-01 2008-11-20 Marioara Mendelovici Amorphous eletriptan hydrobromide and process for preparing it and other forms of eletriptan hydrobromide
US20080319205A1 (en) * 2007-05-29 2008-12-25 Roman Bednar Process for preparing 5-bromo-3-[(R)-1-methyl-pyrrolidin-2-ylmethyl]-1H-indole
US20100285075A1 (en) * 2007-12-17 2010-11-11 Actavis Group Ptc Ehf Novel Hemioxalate Salt of Eletriptan
WO2009142771A2 (en) * 2008-05-22 2009-11-26 Plus Chemicals, S.A. Salts of (r)-5-(2-phenylsulphonylethenyl)-3-(n- methylpyrrolidin-2-ylmethyl)-1h-indole, 5-bromo-3-[(r)-1- methyl-pyrrolidin-2- ylmethyl]-1h-indole and of eletriptan
US8349900B2 (en) * 2008-08-07 2013-01-08 Valeant International Bermuda Bupropion hydrobromide polymorphs
WO2010097703A1 (en) * 2009-02-25 2010-09-02 Actavis Group Ptc Ehf Highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan n-oxide impurity
WO2010116386A2 (en) * 2009-04-08 2010-10-14 Biophore India Pharmaceuticals Pvt. Ltd. Novel polymorph of eletriptan hydrobromide and process for the preparation thereof
IT1393700B1 (it) 2009-04-22 2012-05-08 F S I Fabbrica Italiana Sint Sintesi di 3-{[(2r)-1-metilpirrolidin-2-il]metil}-5-[2-(fenilsulfonil)etil]-1h-indolo
WO2011004391A2 (en) 2009-06-25 2011-01-13 Matrix Laboratories Ltd An improved process for the preparation of eletriptan and its salt thereof
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AU686654B2 (en) * 1993-08-31 1998-02-12 Pfizer Inc. 5-arylindole derivatives

Also Published As

Publication number Publication date
DE69501620D1 (de) 1998-03-19
SK24897A3 (en) 1998-08-05
SA95160156B1 (ar) 2005-05-30
DE69501620T2 (de) 1998-07-02
YU56995A (sh) 1998-07-10
AP576A (en) 1997-03-20
OA10600A (en) 2000-04-06
MY113733A (en) 2002-05-31
AU2735295A (en) 1996-03-22
EP0776323B1 (en) 1998-02-11
BR9503812A (pt) 1996-04-16
DK0776323T3 (da) 1998-03-30
CA2198599C (en) 2000-06-06
GB9417310D0 (en) 1994-10-19
CN1155886A (zh) 1997-07-30
KR970705557A (ko) 1997-10-09
CA2198599A1 (en) 1996-03-07
PL180867B1 (pl) 2001-04-30
IS1850B (is) 2003-02-07
US6110940A (en) 2000-08-29
SI9520091A (sl) 1998-02-28
HU227822B1 (en) 2012-03-28
PE41596A1 (es) 1996-10-12
SK282922B6 (sk) 2003-01-09
SI9520091B (sl) 2004-10-31
LV11800B (en) 1997-10-20
BG61840B1 (bg) 1998-07-31
NZ288210A (en) 1998-01-26
RO116400B1 (ro) 2001-01-30
JP2904588B2 (ja) 1999-06-14
HUT77310A (hu) 1998-03-30
IL115013A0 (en) 1995-12-08
RU2159241C2 (ru) 2000-11-20
EG23822A (en) 2007-09-19
IL115013A (en) 2000-11-21
ES2112650T3 (es) 1998-04-01
ATE163182T1 (de) 1998-02-15
DZ1923A1 (fr) 2002-02-17
CZ287693B6 (en) 2001-01-17
MX9701538A (es) 1997-05-31
TNSN95092A1 (fr) 1996-02-06
FI970800A0 (fi) 1997-02-26
US6380226B1 (en) 2002-04-30
NO970861D0 (no) 1997-02-26
WO1996006842A1 (en) 1996-03-07
EP0776323A1 (en) 1997-06-04
FI113768B (fi) 2004-06-15
NO970861L (no) 1997-02-26
GR3026475T3 (en) 1998-06-30
HRP950460A2 (en) 1997-08-31
HRP950460B1 (en) 2000-02-29
JPH09512283A (ja) 1997-12-09
CO4410334A1 (es) 1997-01-09
CZ56397A3 (cs) 1998-05-13
TR199501061A2 (tr) 1996-06-21
AP9500754A0 (en) 1995-07-31
UA45980C2 (uk) 2002-05-15
NO311297B1 (no) 2001-11-12
FI970800A (fi) 1997-02-26
BRPI9503812B1 (pt) 2017-04-18
IS4401A (is) 1996-12-19
PL318319A1 (en) 1997-06-09
MA23650A1 (fr) 1996-04-01
LV11800A (lv) 1997-06-20
AU691005B2 (en) 1998-05-07
KR100228952B1 (ko) 1999-11-01
BG101250A (en) 1997-09-30
CN1066727C (zh) 2001-06-06
ZA957142B (en) 1997-02-25

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