ES2160668T3 - Procedimiento mejorado para preparar 3-(4-aminoetoxibenzoil)benzo(beta)tiofenos. - Google Patents

Procedimiento mejorado para preparar 3-(4-aminoetoxibenzoil)benzo(beta)tiofenos.

Info

Publication number
ES2160668T3
ES2160668T3 ES95305085T ES95305085T ES2160668T3 ES 2160668 T3 ES2160668 T3 ES 2160668T3 ES 95305085 T ES95305085 T ES 95305085T ES 95305085 T ES95305085 T ES 95305085T ES 2160668 T3 ES2160668 T3 ES 2160668T3
Authority
ES
Spain
Prior art keywords
benzo
thiophenes
pasta
aminoetoxibenzoil
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95305085T
Other languages
English (en)
Spanish (es)
Inventor
Charles Arthur Alt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2160668T3 publication Critical patent/ES2160668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Photoreceptors In Electrophotography (AREA)
ES95305085T 1994-07-22 1995-07-20 Procedimiento mejorado para preparar 3-(4-aminoetoxibenzoil)benzo(beta)tiofenos. Expired - Lifetime ES2160668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27945694A 1994-07-22 1994-07-22

Publications (1)

Publication Number Publication Date
ES2160668T3 true ES2160668T3 (es) 2001-11-16

Family

ID=23069049

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95305085T Expired - Lifetime ES2160668T3 (es) 1994-07-22 1995-07-20 Procedimiento mejorado para preparar 3-(4-aminoetoxibenzoil)benzo(beta)tiofenos.

Country Status (27)

Country Link
US (2) US5523416A (enEXAMPLES)
EP (1) EP0693488B1 (enEXAMPLES)
JP (1) JPH0853440A (enEXAMPLES)
KR (1) KR960004336A (enEXAMPLES)
CN (1) CN1116624A (enEXAMPLES)
AT (1) ATE205842T1 (enEXAMPLES)
AU (1) AU684181B2 (enEXAMPLES)
BR (1) BR9503408A (enEXAMPLES)
CA (1) CA2154319A1 (enEXAMPLES)
CO (1) CO4410192A1 (enEXAMPLES)
CZ (1) CZ189295A3 (enEXAMPLES)
DE (1) DE69522762T2 (enEXAMPLES)
DK (1) DK0693488T3 (enEXAMPLES)
ES (1) ES2160668T3 (enEXAMPLES)
FI (1) FI953513L (enEXAMPLES)
HU (1) HUT71596A (enEXAMPLES)
IL (1) IL114684A (enEXAMPLES)
MX (1) MXPA99010090A (enEXAMPLES)
MY (1) MY131787A (enEXAMPLES)
NO (1) NO952891L (enEXAMPLES)
NZ (1) NZ272609A (enEXAMPLES)
PE (1) PE34396A1 (enEXAMPLES)
PL (1) PL309694A1 (enEXAMPLES)
PT (1) PT693488E (enEXAMPLES)
RU (1) RU95113269A (enEXAMPLES)
TW (1) TW298592B (enEXAMPLES)
ZA (1) ZA956031B (enEXAMPLES)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4410190A1 (es) 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
IN183239B (enEXAMPLES) * 1996-09-25 1999-10-09 Lilly Co Eli
ZA9710262B (en) * 1996-11-19 1999-05-13 Lilly Co Eli Process for the synthesis of benzothiophenes
HUP0003187A3 (en) * 1997-04-30 2002-04-29 Lilly Co Eli Substituted benzothiophenes and process for preparing them
AU2002230409A1 (en) * 2000-11-27 2002-06-03 Eli Lilly And Company Process for preparing 3-aryl-benzo(b)thiophenes
EP1832582A1 (en) 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Novel raloxifene malonic acid addition salts and/or solvates thereof, and pharmaceutical compositions comprising these
ITMI20031333A1 (it) * 2003-06-30 2005-01-01 Erregierre Spa Processo di preparazione di raloxifene cloridrato.
GB2456096B (en) * 2006-10-17 2011-08-17 Cipla Ltd Crystalline form of benzothiophene compound and process for preparation thereof
CN101812002A (zh) * 2010-04-16 2010-08-25 山东新华制药股份有限公司 4-甲氧基-α-[(3-甲氧基苯基)硫代]苯乙酮的合成工艺
CN104496963A (zh) * 2014-12-02 2015-04-08 千辉药业（安徽）有限责任公司 一种盐酸雷洛昔芬的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509682B2 (en) * 1975-10-28 1980-05-22 Eli Lilly And Company 2-Aroyl-3-Phenylbenzothiophene Derivatives
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
AT364852B (de) * 1977-11-05 1981-11-25 Thomae Gmbh Dr K Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen
US4436748A (en) * 1980-10-20 1984-03-13 Hoechst-Roussel Pharmaceuticals Inc. Benzo[b]thiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
IL65378A (en) * 1981-04-03 1986-02-28 Lilly Co Eli Process for preparing 3-(4-aminoethoxybenzoyl)benzo-(b)thiophenes
IL65379A0 (en) * 1981-04-03 1982-05-31 Lilly Co Eli Process for preparing acylated benzothiophenes
EP0062503A1 (en) * 1981-04-03 1982-10-13 Eli Lilly And Company Benzothiophene compounds and process for preparing them
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4436740A (en) * 1982-07-26 1984-03-13 Merck & Co., Inc. 3-Cycloalkylamino-2-OR-propoxycyanopyridines
DE4204969A1 (de) * 1992-02-19 1993-08-26 Basf Ag Verfahren zur herstellung von benzo(b)thiophenen
US5298630A (en) * 1992-06-03 1994-03-29 Sumitomo Seika Chemicals Co., Ltd. Processes for producing 2-substituted benzo[B]thiophene
JP3337728B2 (ja) * 1992-11-20 2002-10-21 イハラケミカル工業株式会社 ２‐アセチルベンゾ［ｂ］チオフェンの製造方法
US5426191A (en) * 1993-12-03 1995-06-20 Warner-Lambert Company Process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides

Also Published As

Publication number Publication date
ATE205842T1 (de) 2001-10-15
HU9502176D0 (en) 1995-09-28
PL309694A1 (en) 1996-02-05
EP0693488A1 (en) 1996-01-24
HUT71596A (en) 1996-01-29
US5512684A (en) 1996-04-30
FI953513A7 (fi) 1996-01-23
BR9503408A (pt) 1996-02-27
DE69522762T2 (de) 2002-07-04
JPH0853440A (ja) 1996-02-27
EP0693488B1 (en) 2001-09-19
CZ189295A3 (en) 1996-02-14
NO952891L (no) 1996-01-23
FI953513A0 (fi) 1995-07-20
PE34396A1 (es) 1996-09-26
DE69522762D1 (de) 2001-10-25
US5523416A (en) 1996-06-04
MXPA99010090A (es) 2004-09-01
FI953513L (fi) 1996-01-23
AU2506895A (en) 1996-02-01
CA2154319A1 (en) 1996-01-23
ZA956031B (en) 1997-01-20
IL114684A (en) 1999-06-20
KR960004336A (ko) 1996-02-23
CO4410192A1 (es) 1997-01-09
DK0693488T3 (da) 2001-11-12
CN1116624A (zh) 1996-02-14
TW298592B (enEXAMPLES) 1997-02-21
NZ272609A (en) 1997-05-26
AU684181B2 (en) 1997-12-04
PT693488E (pt) 2002-02-28
MY131787A (en) 2007-08-30
IL114684A0 (en) 1995-11-27
NO952891D0 (no) 1995-07-20
RU95113269A (ru) 1997-06-10

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