EA199800029A1 - СПОСОБ ПОЛУЧЕНИЯ БЕНЗО[b]ТИОФЕНОВ - Google Patents

СПОСОБ ПОЛУЧЕНИЯ БЕНЗО[b]ТИОФЕНОВ

Info

Publication number
EA199800029A1
EA199800029A1 EA199800029A EA199800029A EA199800029A1 EA 199800029 A1 EA199800029 A1 EA 199800029A1 EA 199800029 A EA199800029 A EA 199800029A EA 199800029 A EA199800029 A EA 199800029A EA 199800029 A1 EA199800029 A1 EA 199800029A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tiophenes
benzo
obtaining
obtaining benzo
arylbenzo
Prior art date
Application number
EA199800029A
Other languages
English (en)
Other versions
EA000377B1 (ru
Inventor
Дэвид В. Хоард
Уэйн Д. Льюк
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA199800029A1 publication Critical patent/EA199800029A1/ru
Publication of EA000377B1 publication Critical patent/EA000377B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

В настоящем изобретении предложен новый способ синтеза 2-арилбензо[b]тиофенов.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800029A 1995-06-07 1996-06-04 СПОСОБЫ ПОЛУЧЕНИЯ БЕНЗО[b]ТИОФЕНОВ EA000377B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/481,015 US5606075A (en) 1995-06-07 1995-06-07 Process for the synthesis of benzo[b]thiophenes
PCT/US1996/009477 WO1996040677A1 (en) 1995-06-07 1996-06-04 PROCESS FOR THE SYNTHESIS OF BENZO[b]THIOPHENES

Publications (2)

Publication Number Publication Date
EA199800029A1 true EA199800029A1 (ru) 1998-08-27
EA000377B1 EA000377B1 (ru) 1999-06-24

Family

ID=23910245

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800029A EA000377B1 (ru) 1995-06-07 1996-06-04 СПОСОБЫ ПОЛУЧЕНИЯ БЕНЗО[b]ТИОФЕНОВ

Country Status (17)

Country Link
US (1) US5606075A (ru)
EP (2) EP0830355A4 (ru)
JP (1) JPH11507347A (ru)
KR (1) KR19990022501A (ru)
CN (1) CN1192738A (ru)
AU (1) AU703017B2 (ru)
BR (1) BR9608851A (ru)
CA (1) CA2223709A1 (ru)
CZ (1) CZ387897A3 (ru)
EA (1) EA000377B1 (ru)
HU (1) HUP9900898A3 (ru)
IL (1) IL122128A (ru)
NO (1) NO975627L (ru)
NZ (1) NZ310248A (ru)
PL (1) PL323906A1 (ru)
TR (1) TR199701509T1 (ru)
WO (1) WO1996040677A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU717844B2 (en) * 1996-07-24 2000-04-06 Teikoku Hormone Mfg. Co., Ltd. Process for the preparation of 2,6-disubstituted benzothiophene compounds
MY118009A (en) * 1996-09-25 2004-08-30 Lilly Co Eli Process for the synthesis of benzothiophenes
ZA9710262B (en) * 1996-11-19 1999-05-13 Lilly Co Eli Process for the synthesis of benzothiophenes
US20040044224A1 (en) * 2001-08-21 2004-03-04 Conrad Preston Charles Process for preparing 2-phenyl-3-aminobenzothiophenes
EP1832582A1 (en) 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Novel raloxifene malonic acid addition salts and/or solvates thereof, and pharmaceutical compositions comprising these
GB2456096B (en) * 2006-10-17 2011-08-17 Cipla Ltd Crystalline form of benzothiophene compound and process for preparation thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2478914A (en) * 1948-03-23 1949-08-16 Shell Dev Production of benzothiophenes
US3271414A (en) * 1964-05-12 1966-09-06 Mobil Oil Corp Preparation of benzofuran, benzothiophene, and indoles
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
EP0433233B1 (de) * 1989-12-14 1995-01-25 Ciba-Geigy Ag Heterocyclische Verbindungen
US5169961A (en) * 1991-11-22 1992-12-08 Abbott Laboratories Process for the production of 2-acetylbenzo [β]thiophenes
DE4204969A1 (de) * 1992-02-19 1993-08-26 Basf Ag Verfahren zur herstellung von benzo(b)thiophenen
US5298630A (en) * 1992-06-03 1994-03-29 Sumitomo Seika Chemicals Co., Ltd. Processes for producing 2-substituted benzo[B]thiophene
FR2695930B1 (fr) * 1992-09-22 1994-12-23 Sanofi Elf Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
JP3337728B2 (ja) * 1992-11-20 2002-10-21 イハラケミカル工業株式会社 ２‐アセチルベンゾ［ｂ］チオフェンの製造方法
NZ250916A (en) * 1993-02-27 1995-08-28 Nihon Nohyaku Co Ltd N-heteroaryl-n'-phenylureas, their use as acat inhibitors
US5426191A (en) * 1993-12-03 1995-06-20 Warner-Lambert Company Process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides
US5466810A (en) * 1994-06-10 1995-11-14 Eli Lilly And Company 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes

Also Published As

Publication number Publication date
NO975627L (no) 1998-01-27
US5606075A (en) 1997-02-25
CN1192738A (zh) 1998-09-09
KR19990022501A (ko) 1999-03-25
AU703017B2 (en) 1999-03-11
EA000377B1 (ru) 1999-06-24
EP1092714A2 (en) 2001-04-18
MX9709129A (es) 1998-03-31
CZ387897A3 (cs) 1998-07-15
JPH11507347A (ja) 1999-06-29
NZ310248A (en) 1999-01-28
IL122128A0 (en) 1998-04-05
HUP9900898A3 (en) 2000-02-28
BR9608851A (pt) 1999-06-08
EP0830355A1 (en) 1998-03-25
NO975627D0 (no) 1997-12-04
WO1996040677A1 (en) 1996-12-19
IL122128A (en) 2001-08-08
CA2223709A1 (en) 1996-12-19
HUP9900898A2 (hu) 1999-07-28
TR199701509T1 (xx) 1998-03-21
PL323906A1 (en) 1998-04-27
EP1092714A3 (en) 2001-07-04
EP0830355A4 (en) 1998-09-30
AU6101096A (en) 1996-12-30

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU