ES2131178T3 - Tecnica de tratamiento extracorporal de la sangre. - Google Patents

Tecnica de tratamiento extracorporal de la sangre.

Info

Publication number
ES2131178T3
ES2131178T3 ES94420030T ES94420030T ES2131178T3 ES 2131178 T3 ES2131178 T3 ES 2131178T3 ES 94420030 T ES94420030 T ES 94420030T ES 94420030 T ES94420030 T ES 94420030T ES 2131178 T3 ES2131178 T3 ES 2131178T3
Authority
ES
Spain
Prior art keywords
primary
blood
priming
chamber
circuit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94420030T
Other languages
English (en)
Other versions
ES2131178T5 (es
Inventor
Lori Truitt
Douglas P Miller
Steven H Johnson
Iii Frank Corbin
Keith Manica
Lawrence L Leppert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gambro Industries SAS
Original Assignee
Hospal Industrie SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21783342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2131178(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hospal Industrie SAS filed Critical Hospal Industrie SAS
Application granted granted Critical
Publication of ES2131178T3 publication Critical patent/ES2131178T3/es
Publication of ES2131178T5 publication Critical patent/ES2131178T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • A61M1/1643Constructional aspects thereof with weighing of fresh and used dialysis fluid
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403Regulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
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    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3431Substitution fluid path upstream of the filter
    • A61M1/3434Substitution fluid path upstream of the filter with pre-dilution and post-dilution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3437Substitution fluid path downstream of the filter, e.g. post-dilution with filtrate
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/3441Substitution rate control as a function of the ultrafiltration rate
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    • A61M1/3451Substitution rate control as a function of the ultrafiltration rate the difference in weight between both ultra-filtrate and substitution reservoir being used as control signal
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3643Priming, rinsing before or after use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/3621Extra-corporeal blood circuits
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    • A61M1/3644Mode of operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3643Priming, rinsing before or after use
    • A61M1/3644Mode of operation
    • A61M1/3646Expelling the residual body fluid after use, e.g. back to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3643Priming, rinsing before or after use
    • A61M1/3644Mode of operation
    • A61M1/365Mode of operation through membranes, e.g. by inverted trans-membrane pressure [TMP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672Means preventing coagulation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • GPHYSICS
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • A61M2205/00General characteristics of the apparatus
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    • A61M2205/3331Pressure; Flow
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    • Y10S210/00Liquid purification or separation
    • Y10S210/929Hemoultrafiltrate volume measurement or control processes

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  • Heart & Thoracic Surgery (AREA)
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  • Neurosurgery (AREA)

Abstract

EL APARATO LLEVA A CABO Y CONTROLA AUTOMATICAMENTE EL TRATAMIENTO EXTRACORPOREO DE LA SANGRE DE UN PACIENTE MEDIANTE UN TRATAMIENTO SELECCIONADO DE ENTRE UNA PLURALIDAD DE TRATAMIENTOS PREDETERMINADOS. CADA UNO DE LOS TRATAMIENTOS CONSISTE EN QUE LA SANGRE FLUYA DESDE EL PACIENTE A UNA CAMARA PRIMARIA (44) DE UNA UNIDAD DE FILTRACION (40), PASE A TRAVES DE UNA MEMBRANA SEMIPERMEABLE (42) QUE HAY COLOCADA EN LA UNIDAD DE FILTRACION (40) LA CUAL SEPARA LA CAMARA PRIMARIA (44) DE UNA CAMARA SECUNDARIA (46) DE LA UNIDAD DE FILTRACION (40), SALGA DE LA UNIDAD DE FILTRACION Y VUELVA AL PACIENTE. SE AÑADE SELECTIVAMENTE Y DE MANERA CONTROLADA UN FLUIDO DE SUSTITUCION A LA SANGRE, SEGUN SE REQUIERA PARA EL TRATAMIENTO SELECCIONADO. SE INTRODUCE DE MANERA SELECTIVA Y CONTROLADA UN FLUIDO SECUNDARIO EN LA CAMARA SECUNDARIA (46) DE UNA UNIDAD DE FILTRACION (40) PARA RECOGER DE MANERA CONTROLADA EL MATERIAL QUE PASA A TRAVES DE LA MEMBRANA SEMIPERMEABLE (42) DESDE LA SANGRE O PARA SUMINISTRAR MATERIALPARA QUE PASE A TRAVES DE LA MEMBRANA SEMIPERMEABLE (42) Y ENTRE EN LA SANGRE SEGUN SE REQUIERA PARA EL TRATAMIENTO SELECCIONADO. LOS MATERIALES SE RETIRAN DE LA CAMARA SECUNDARIA (46) Y SE RECOGEN SEGUN EL TRATAMIENTO SELECCIONADO. TRAS LA SELECCION DE UNO DE LOS TRATAMIENTOS DE ENTRE LA PLURALIDAD DE TRATAMIENTOS EXTRACORPOREOS DE LA SANGRE, SE DETERMINAN, ESTABLECEN Y CONTROLAN AUTOMATICAMENTE LAS VELOCIDADES DE CIRCULACION DE LA SANGRE, DE CIRCULACION DEL FLUIDO Y DE LA RECOGIDA DEL FLUIDO SEGUN EL TRATAMIENTO SELECCIONADO.
ES94420030T 1993-02-12 1994-02-01 Tecnica para el tratamiento extracorporeo de sangre. Expired - Lifetime ES2131178T5 (es)

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US17571 1993-02-12
US08/017,571 US5910252A (en) 1993-02-12 1993-02-12 Technique for extracorporeal treatment of blood

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ES97120159T Expired - Lifetime ES2163082T3 (es) 1993-02-12 1994-02-01 Metodo para cebar un circuito para multiples tratamientos extracorporeos de sangre.

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ATE205096T1 (de) 2001-09-15
CA2580848A1 (en) 1994-08-13
ES2163082T3 (es) 2002-01-16
US5776345A (en) 1998-07-07
US5762805A (en) 1998-06-09
EP0611228B2 (en) 2005-08-17
CA2580848C (en) 2008-12-23
GR3030578T3 (en) 1999-10-29
DE69417608D1 (de) 1999-05-12
US5679245A (en) 1997-10-21
DE69428220T2 (de) 2002-06-13
ES2131178T5 (es) 2006-04-01
EP0611228A2 (en) 1994-08-17
JP3591864B2 (ja) 2004-11-24
CA2444794C (en) 2007-06-19
DE69428220D1 (de) 2001-10-11
ATE178496T1 (de) 1999-04-15
CA2115414A1 (en) 1994-08-13
CA2444794A1 (en) 1994-08-13
DE69417608T3 (de) 2006-07-27
DE69417608T2 (de) 1999-09-30
US5910252A (en) 1999-06-08
EP0611228B1 (en) 1999-04-07
EP0829265B1 (en) 2001-09-05
CA2115414C (en) 2004-01-20
EP0611228A3 (en) 1994-12-21
JPH06315530A (ja) 1994-11-15
EP0829265A1 (en) 1998-03-18
DE9422431U1 (de) 2002-04-25

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