ES2130321T3 - Compuestos de fosforo opticamente activos. - Google Patents

Compuestos de fosforo opticamente activos.

Info

Publication number
ES2130321T3
ES2130321T3 ES94114992T ES94114992T ES2130321T3 ES 2130321 T3 ES2130321 T3 ES 2130321T3 ES 94114992 T ES94114992 T ES 94114992T ES 94114992 T ES94114992 T ES 94114992T ES 2130321 T3 ES2130321 T3 ES 2130321T3
Authority
ES
Spain
Prior art keywords
compounds
phosphorus compounds
alcoxi
optically active
active phosphorus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94114992T
Other languages
English (en)
Inventor
Emil Albin Broger
Marco Cereghetti
Alain Rageot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2130321T3 publication Critical patent/ES2130321T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5027—Polyphosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6568—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms
    • C07F9/65683—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms the ring phosphorus atom being part of a phosphine

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS COMPUESTOS DE FOSFORO ACTIVOS OPTICOS DE LA FORMULA GENERAL DONDE R Y R1 DE FORMA INDEPENDIENTE UNO DE OTRO SIGNIFICAN HIDROXI, UN HIDROXI PROTEGIDO, ALQUIL INFERIOR O ALCOXI INFERIOR Y R2 HASTA R5 DE FORMA INDEPENDIENTE UNO DE OTRO SIGNIFICAN ALQUIL CON 3 HASTA 7 ATOMOS DE CARBONO, CICLOALQUIL O ARIL, O R2 Y R3 O R4 Y R5 CONJUNTAMENTE CON EL FOSFORO SIGNIFICAN UN GRUPO DE LA FORMULA CON LA CONDICION DE QUE AL MISMO TIEMPO NO SEAN IGUALES R2 Y R3 Y R4 Y R5, LA ELABORACION DE TALES COMPUESTOS, SU UTILIZACION PARA REACCIONES ENANTIOSELECTIVAS, COMO POR EJEMPLO HIDROGENACION ASIMETRICA, DESPLAZAMIENTO DE HIDROGENO ENANTIOSELECTIVO EN SISTEMA PROQUIRALES, ALILICOS Y SIMILARES, ASI COMO COMPLEJOS DE LOS COMPUESTOS DE LA FORMULA I CON METALES DEL GRUPO VIII.
ES94114992T 1993-10-08 1994-09-23 Compuestos de fosforo opticamente activos. Expired - Lifetime ES2130321T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH303893 1993-10-08

Publications (1)

Publication Number Publication Date
ES2130321T3 true ES2130321T3 (es) 1999-07-01

Family

ID=4247229

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94114992T Expired - Lifetime ES2130321T3 (es) 1993-10-08 1994-09-23 Compuestos de fosforo opticamente activos.

Country Status (7)

Country Link
US (1) US5516944A (es)
EP (1) EP0647648B1 (es)
JP (1) JP3723241B2 (es)
AT (1) ATE177427T1 (es)
DE (1) DE59407903D1 (es)
DK (1) DK0647648T3 (es)
ES (1) ES2130321T3 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19620023C2 (de) * 1996-05-17 2001-03-08 Celanese Chem Europe Gmbh Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane
US5874629A (en) * 1996-06-12 1999-02-23 Merck & Co., Inc. Chiral bisphosphines
FR2750423B1 (fr) * 1996-06-28 1998-08-14 Rhone Poulenc Chimie Procede d'hydrogenation asymetrique d'un compose cetonique
JP3493266B2 (ja) * 1996-08-27 2004-02-03 高砂香料工業株式会社 新規な光学活性ジホスフィン化合物、該化合物を製造す る方法、該化合物を配位子とする遷移金属錯体並びに該 錯体を用いた光学活性体の製造方法
JP3441605B2 (ja) * 1996-10-30 2003-09-02 高砂香料工業株式会社 新規光学活性ジホスフィン及び該化合物より得られる遷移金属錯体及び該錯体の存在下にて光学活性体を得る方法
US5936127A (en) * 1997-01-13 1999-08-10 The Penn State Research Foundation Asymmetric synthesis and catalysis with chiral heterocyclic compounds
US5874628A (en) * 1997-03-26 1999-02-23 Monsanto Company Method for preparation of tertiary phosphines via nickel-catalyzed cross coupling
US6207868B1 (en) * 1997-06-13 2001-03-27 The Penn State Research Foundation Asymmetric synthesis catalyzed by transition metal complexes with chiral ligands
US5886182A (en) * 1997-12-10 1999-03-23 The Hong Kong Polytechnic University Chiral pyridylphosphines and their application in asymmetric catalytic hydrogenation of 2-arylpropenoic acids
US6307087B1 (en) 1998-07-10 2001-10-23 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
ATE316532T1 (de) * 1998-07-10 2006-02-15 Massachusetts Inst Technology Liganden für metalle und metall-katalysiertes verfahren
US7223879B2 (en) 1998-07-10 2007-05-29 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
US6395916B1 (en) 1998-07-10 2002-05-28 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
DE19838742A1 (de) * 1998-08-26 2000-03-02 Celanese Chem Europe Gmbh Valeraldehyd und Verfahren zu seiner Herstellung
ATE243216T1 (de) 1998-11-19 2003-07-15 Solvias Ag Chirale diphenyldiphosphine und d-8 metall- komplexe davon
FR2812638B1 (fr) * 2000-08-03 2003-04-25 Ppg Sipsy Utilisation de diphosphines chirales comme ligands optiquement actifs pour la preparation de complexes diphosphino-metalliques, les complexes ainsi obtenus et les procedes de catalyse asymetrique les mettant en oeuvre
SG124249A1 (en) * 2001-12-07 2006-08-30 Sumitomo Chemical Co New polymer and polymer light-emitting device using the same
JP4231274B2 (ja) * 2002-11-12 2009-02-25 高砂香料工業株式会社 ホスフィン化合物、該化合物を配位子とする遷移金属錯体及び該錯体を含む不斉合成用触媒
DK2583958T3 (en) * 2002-12-09 2016-11-28 Massachusetts Inst Of Tech (Mit) LIGANDS OF METALS AND IMPROVED METAL catalyzed processes based thereon
DK1720852T3 (da) 2004-02-19 2012-10-22 Lonza Ag Fremgangsmåde til fremstilling af enantiomerrene 1-substituerede 3-aminoalkoholer
EP1609795A1 (en) * 2004-06-25 2005-12-28 Lonza AG Process for the preparation of asymmetrically substituted biaryldiphosphines
KR20070029264A (ko) * 2004-06-25 2007-03-13 론자 아게 비대칭 치환 비아릴디포스핀의 제조 방법
EP1761549A1 (en) * 2004-06-25 2007-03-14 Lonza Ag Process for the preparation of asymmetrically substituted biaryldiphosphines
JP5546781B2 (ja) * 2009-03-10 2014-07-09 日本化学工業株式会社 ２，２’−ビス（ジアルキルホスフィノ）ビフェニル化合物及びその製造方法並びに該化合物を配位子とする金属錯体
MX338725B (es) 2010-07-16 2016-04-28 Abbvie Bahamas Ltd Ligando de fosfina para reacciones cataliticas.
AU2014280934B2 (en) * 2010-07-16 2017-03-16 Abbvie Ireland Unlimited Company Phosphine ligands for catalytic reactions
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
MY167881A (en) 2010-07-16 2018-09-26 Abbvie Bahamas Ltd Process for preparing antiviral compounds
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
JP5634802B2 (ja) * 2010-09-02 2014-12-03 和光純薬工業株式会社 新規酸素架橋型超原子価ヨウ素化合物及びこれを含有する酸化剤
WO2016093175A1 (ja) * 2014-12-12 2016-06-16 国立大学法人名古屋大学 トリ（ヘテロ）アリールアセトニトリル化合物の製造方法
CN108659041B (zh) 2017-12-13 2020-04-10 浙江大学 基于四甲基螺二氢茚骨架的膦配体化合物及其中间体和制备方法与用途
CN108659045B (zh) 2018-01-03 2020-04-10 浙江大学 基于四甲基螺二氢茚骨架的膦-噁唑啉配体化合物及其制备方法和用途
CN108690074A (zh) * 2018-05-15 2018-10-23 东华大学 一种兼有磷中心手性和联萘轴手性的双膦手性化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK350383A (da) * 1982-08-27 1984-02-28 Hoffmann La Roche Phosphorforbindelser
US4694109A (en) * 1986-06-13 1987-09-15 Eastman Kodak Company Chelate ligands for low pressure hydroformylation catalyst and process employing same
JPH0733392B2 (ja) * 1989-06-16 1995-04-12 高砂香料工業株式会社 ２，２’―ビス〔ジー（ｍ―トリル）ホスフィノ〕―１，１’―ビナフチル
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 ２，２’―ビス（ジシクロヘキシルホスフィノ）―６，６’―ジメチル―１，１’―ビフェニルを配位子とする錯体，およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
JPH0474192A (ja) * 1990-07-12 1992-03-09 Takasago Internatl Corp ２，２′―ビス（ジシクロペンチルホスフィノ）―１，１′―ビナフチル及びこれれを配位子とする遷移金属錯体
US5302738A (en) * 1991-03-15 1994-04-12 Hoffmann-La Roche Inc. Chiral phosphines
ATE135008T1 (de) * 1991-03-15 1996-03-15 Hoffmann La Roche Chirale phosphine
WO1993015089A1 (de) * 1992-01-31 1993-08-05 F. Hoffmann-La Roche Ag Diphosphinliganden

Also Published As

Publication number Publication date
ATE177427T1 (de) 1999-03-15
JP3723241B2 (ja) 2005-12-07
JPH07149777A (ja) 1995-06-13
US5516944A (en) 1996-05-14
EP0647648B1 (de) 1999-03-10
DE59407903D1 (de) 1999-04-15
EP0647648A1 (de) 1995-04-12
DK0647648T3 (da) 1999-09-27

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