ES2116435T3 - Ligandos difosfinicos. - Google Patents

Ligandos difosfinicos.

Info

Publication number
ES2116435T3
ES2116435T3 ES93902011T ES93902011T ES2116435T3 ES 2116435 T3 ES2116435 T3 ES 2116435T3 ES 93902011 T ES93902011 T ES 93902011T ES 93902011 T ES93902011 T ES 93902011T ES 2116435 T3 ES2116435 T3 ES 2116435T3
Authority
ES
Spain
Prior art keywords
pct
formula
group
sec
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93902011T
Other languages
English (en)
Inventor
Emil Albin Broger
Marco Cereghetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2116435T3 publication Critical patent/ES2116435T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6568—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms
    • C07F9/65683—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms the ring phosphorus atom being part of a phosphine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5027—Polyphosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring

Abstract

SE DESCRIBEN NUEVOS COMPUESTOS DE FOSFORO OPTICAMENTE ACTIVOS Y RACEMICOS DE FORMULA (I).SIENDO;R ALQUILO DE BAJO NUMERO DE CARBONOS , ALCOXI DE BAJO NUMERO DE CARBONOS , HIDROXI O UN GRUPO HIDROXI PROTEGIDO Y R(1) Y R(2) DIFERENTES ENTRE SI Y REPRESENTAN ALQUILO DE BAJO NUMERO DE CARBONOS , CICLOALQUILO, ARILO , UN HETEROAROMATICO DE CINCO MIEMBROS O UN GRUPO DE FORMULA (A).LOS COMPUESTOS DE FORMULA (I) SE UTILIZAN EN FORMA DE COMPLEJOS CON UN METAL DEL GRUPO VIII COMO CATALIZADORES PARA HIDROGENACION ASIMETRICA Y DESPLAZAMIENTO ENANTIOSELECTIVO DE HIDROGENO EN SISTEMAS ALILICOS PROQUILARES
ES93902011T 1992-01-31 1993-01-22 Ligandos difosfinicos. Expired - Lifetime ES2116435T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH29092 1992-01-31
CH13293 1993-01-18

Publications (1)

Publication Number Publication Date
ES2116435T3 true ES2116435T3 (es) 1998-07-16

Family

ID=25683615

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93902011T Expired - Lifetime ES2116435T3 (es) 1992-01-31 1993-01-22 Ligandos difosfinicos.

Country Status (8)

Country Link
US (1) US5508438A (es)
EP (1) EP0582692B1 (es)
JP (1) JP3369560B2 (es)
AT (1) ATE165361T1 (es)
DE (1) DE59308424D1 (es)
DK (1) DK0582692T3 (es)
ES (1) ES2116435T3 (es)
WO (1) WO1993015089A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332846A (en) * 1993-06-01 1994-07-26 Eastman Kodak Company Hydroformylation process using novel phosphine-rhodium catalyst system
DE4333307A1 (de) * 1993-09-30 1995-04-06 Hoechst Ag Cyclische Verbindungen des dreiwertigen Phosphors
DK0647648T3 (da) * 1993-10-08 1999-09-27 Hoffmann La Roche Optisk aktive phosphorforbindelser
US5536858A (en) * 1994-02-12 1996-07-16 Hoffmann-La Roche Inc. Tetrasulfonated diphosphine compounds and metal complexes thereof for asymmetric catalytic reactions
IT1270082B (it) * 1994-07-12 1997-04-28 Univ Degli Studi Milano Difosfine eteroaromatiche come leganti chirali, complessi tra dette difosfine e metalli di transizione ed impiego di detti complessi come catalizzatori chirali
DE4434844A1 (de) * 1994-09-29 1996-04-04 Hoechst Ag Diphosphane und Verfahren zu ihrer Herstellung
DE19506279A1 (de) * 1995-02-23 1996-08-29 Hoechst Ag Sulfonierte Diphosphane und ein Verfahren zu ihrer Herstellung
JP3789508B2 (ja) * 1995-03-14 2006-06-28 高砂香料工業株式会社 光学活性非対称ジホスフィン及び該化合物の存在下にて光学活性体を得る方法
JP3338243B2 (ja) * 1995-07-21 2002-10-28 高砂香料工業株式会社 光学活性非対称ジホスフィン化合物及びその製造方法
CA2240107C (en) * 1997-07-02 2008-04-15 F. Hoffmann-La Roche Ag Novel diphenylarsines
US5886182A (en) * 1997-12-10 1999-03-23 The Hong Kong Polytechnic University Chiral pyridylphosphines and their application in asymmetric catalytic hydrogenation of 2-arylpropenoic acids
DE19838742A1 (de) * 1998-08-26 2000-03-02 Celanese Chem Europe Gmbh Valeraldehyd und Verfahren zu seiner Herstellung
FR2812638B1 (fr) * 2000-08-03 2003-04-25 Ppg Sipsy Utilisation de diphosphines chirales comme ligands optiquement actifs pour la preparation de complexes diphosphino-metalliques, les complexes ainsi obtenus et les procedes de catalyse asymetrique les mettant en oeuvre
DE10044793A1 (de) 2000-09-11 2002-04-04 Bayer Ag Diphosphine
AU2002216719A1 (en) 2000-11-17 2002-05-27 The Penn State Research Foundation Ortho substituted chiral phosphines and phosphinites and their use in asymmetriccatayltic reactions
DE102005005946A1 (de) * 2005-02-10 2006-08-17 Basf Ag Verfahren zur Herstellung tertiärer Phosphine
EP2231680B1 (en) * 2007-12-12 2018-03-28 Massachusetts Institute of Technology Ligands for transition-metal-catalyzed cross-couplings, and methods of use thereof
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
UA115025C2 (uk) 2010-07-16 2017-09-11 Еббві Айрленд Анлімітед Компані Спосіб одержання противірусних сполук
BR112013001138A2 (pt) 2010-07-16 2016-07-05 Abbvie Inc ligantes de fosfina para reações catalíticas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK350383A (da) * 1982-08-27 1984-02-28 Hoffmann La Roche Phosphorforbindelser
JPS6163690A (ja) * 1984-09-04 1986-04-01 Takasago Corp ルテニウム−ホスフイン錯体
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 ２，２’―ビス（ジシクロヘキシルホスフィノ）―６，６’―ジメチル―１，１’―ビフェニルを配位子とする錯体，およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
DE59205555D1 (de) * 1991-03-15 1996-04-11 Hoffmann La Roche Chirale phosphine

Also Published As

Publication number Publication date
JP3369560B2 (ja) 2003-01-20
DE59308424D1 (de) 1998-05-28
DK0582692T3 (da) 1999-01-25
ATE165361T1 (de) 1998-05-15
EP0582692B1 (de) 1998-04-22
JPH06506484A (ja) 1994-07-21
WO1993015089A1 (de) 1993-08-05
US5508438A (en) 1996-04-16
EP0582692A1 (de) 1994-02-16

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