HUP0100419A2 - Átmenetifémekkel katalizált eljárás, a katalizátorokhoz alkalmazható királis ligandumok, és előállításuk - Google Patents

Átmenetifémekkel katalizált eljárás, a katalizátorokhoz alkalmazható királis ligandumok, és előállításuk

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Publication number
HUP0100419A2
HUP0100419A2 HU0100419A HUP0100419A HUP0100419A2 HU P0100419 A2 HUP0100419 A2 HU P0100419A2 HU 0100419 A HU0100419 A HU 0100419A HU P0100419 A HUP0100419 A HU P0100419A HU P0100419 A2 HUP0100419 A2 HU P0100419A2
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Hungary
Prior art keywords
catalyzes
preparation
transition metal
chiral ligands
catalyzed reaction
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HU0100419A
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English (en)
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Xumu Zhang
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The Penn State Research Foundation
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Publication of HUP0100419A2 publication Critical patent/HUP0100419A2/hu
Publication of HUP0100419A3 publication Critical patent/HUP0100419A3/hu

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    • B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
    • B01J31/181—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine
    • B01J31/1815—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine with more than one complexing nitrogen atom, e.g. bipyridyl, 2-aminopyridine
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A találmány szerinti oxazolini-amino-csoportokattartalmazó királis ligandumok az átmeneti fémekkel aszimmetrikusreakciókban megnövelt enantioszelektivitású katalizátort képeznek. Akirális ligandumok szerkezete (I), (II) (III) vagy (IV) általánosképletnek felel meg, ahol R, R1, R2, R3, R4, R5, R6 és R7 jelentéseegymástól függetlenül hidrogénatom, alkilcsoport, arilcsoport,helyettesített alkilcsoport vagy helyettesített arilcsoport, ahol R1,R2, R3 és R4 közül bármelyik két helyettesítő egymással gyűrűsszerkezetté kapcsolódhat össze, és ahol R5, R6 és R7 közül bármelyikkét helyettesítő egymással gyűrűs szerkezetté kapcsolódhat össze, és nértéke 1 vagy 2. A találmány szerint az aszimmetrikus reakcióbanmegnövelt enantioszelektivitású katalizátor előállítása során imidát-észtert királis alkohollal redukálnak. Ó
HU0100419A 1997-11-12 1998-11-12 Transition metal-catalyzed reaction, chiral ligands for these catalyzes and their preparation HUP0100419A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6550297P 1997-11-12 1997-11-12
PCT/US1998/024036 WO1999024410A1 (en) 1997-11-12 1998-11-12 Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands

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HUP0100419A2 true HUP0100419A2 (hu) 2001-05-28
HUP0100419A3 HUP0100419A3 (en) 2001-10-29

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US (2) US6255493B1 (hu)
EP (1) EP1030849A1 (hu)
JP (1) JP2001522838A (hu)
KR (1) KR20010031960A (hu)
CN (1) CN1278801A (hu)
AU (1) AU1398199A (hu)
BR (1) BR9814167A (hu)
CA (1) CA2308415A1 (hu)
HU (1) HUP0100419A3 (hu)
IL (1) IL135854A0 (hu)
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TR (1) TR200001333T2 (hu)
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EP1030849A1 (en) * 1997-11-12 2000-08-30 The Pennsylvania State University Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands
US6239285B1 (en) 1998-02-06 2001-05-29 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
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AU2002318538A1 (en) * 2002-07-15 2004-02-02 Nippon Soda Co., Ltd. Ruthenium compounds, diamine ligands, and process for preparation of optically active alcohols
CN100364981C (zh) * 2003-01-29 2008-01-30 北京大学 手性二苯并[a,c]环庚二烯双噁唑啉配体化合物及其制备与应用
GB0313661D0 (en) * 2003-06-13 2003-07-16 Avecia Ltd Process
GB0316439D0 (en) 2003-07-15 2003-08-20 Johnson Matthey Plc Catalysts
GB0329284D0 (en) * 2003-12-18 2004-01-21 Avecia Ltd Process
ITPD20040115A1 (it) * 2004-05-04 2004-08-04 Univ Degli Studi Udine Complessi di rutenio con 2-(amminometil)piridine e fosfine, loro preparazione ed uso come catalizzatori
CN100348597C (zh) * 2005-12-29 2007-11-14 上海交通大学 5，5’位连接的1, 1’－联苯类轴手性配体的合成方法
CN100425598C (zh) * 2006-09-09 2008-10-15 合肥工业大学 一种手性噁唑啉及其制备方法
ITPD20070237A1 (it) 2007-07-11 2009-01-12 Univ Degli Studi Udine Nuovi leganti della classe della benzo[h]chinolina e complessi di metalli di transizione che li contengono e uso di tali complessi come catalizzatori
CN101773856B (zh) * 2010-01-21 2012-06-27 北京理工大学 一种噁唑啉西佛碱配体金属络合物催化剂及其应用
CN102199130A (zh) * 2011-03-22 2011-09-28 罗梅 一种手性噁唑啉的制备及合成方法
CN102206212B (zh) * 2011-04-06 2013-07-03 罗梅 一种手性噁唑啉的制备及合成方法
CN104119288B (zh) * 2013-04-26 2016-05-25 中国科学院大连化学物理研究所 一种含氮四齿有机配体的合成方法
CN105481622A (zh) * 2015-12-14 2016-04-13 武汉凯特立斯科技有限公司 一种α-氧代-α,β-不饱和羧酸的不对称氢化方法
CN106588987B (zh) * 2016-11-30 2019-09-24 上海师范大学 一种手性噁唑啉类nnp型配体及其合成方法和应用

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US3192224A (en) * 1963-03-11 1965-06-29 Coastal Interchemical Company Aminomethyl oxazolines and process of preparing same
DE2220413A1 (de) * 1972-04-26 1973-11-15 Huels Chemische Werke Ag 2-aminoalkylsubstituierte cyclische imidsaeureester und verfahren zu deren herstellung
HU167760B (hu) * 1972-10-20 1975-12-25
PT77428B (fr) * 1982-10-05 1986-02-27 Cortial Procede pour preparer de nouvelles amino-2-substitue-5-oxazoli-nes-2 et des compositions les contenant
DE19548399A1 (de) * 1995-12-22 1997-06-26 Basf Ag Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen
EP1030849A1 (en) * 1997-11-12 2000-08-30 The Pennsylvania State University Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands

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US6451727B2 (en) 2002-09-17
WO1999024410A1 (en) 1999-05-20
CA2308415A1 (en) 1999-05-20
TR200001333T2 (tr) 2000-10-23
JP2001522838A (ja) 2001-11-20
IL135854A0 (en) 2001-05-20
US6255493B1 (en) 2001-07-03
KR20010031960A (ko) 2001-04-16
YU29300A (sh) 2003-08-29
EP1030849A1 (en) 2000-08-30
BR9814167A (pt) 2000-09-26
AU1398199A (en) 1999-05-31
HUP0100419A3 (en) 2001-10-29
US20010044546A1 (en) 2001-11-22
PL340767A1 (en) 2001-02-26

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